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The map label for this gene is yegB [H]

Identifier: 29141245

GI number: 29141245

Start: 822836

End: 824248

Strand: Reverse

Name: yegB [H]

Synonym: t0743

Alternate gene names: 29141245

Gene position: 824248-822836 (Counterclockwise)

Preceding gene: 29141246

Following gene: 29141244

Centisome position: 17.2

GC content: 54.21

Gene sequence:

>1413_bases
ATGACAGAATTTCCTGACAACACCCGCTGGCAACTCTGGATTGTGGCATTCGGCTTTTTTATGCAGTCGCTGGATACCAC
CATCGTCAACACTGCGCTGCCTTCCATGGCGAAAAGCCTGGGGGAAAGCCCGCTGCATATGCACATGGTAGTGGTGTCAT
ATGTTCTCACCGTCGCCGTGATGCTCCCCGCCAGCGGCTGGCTGGCAGACAAAATCGGCGTGCGTAATATTTTCTTTGCC
GCCATCGTGCTGTTCACGCTGGGTTCGCTGTTTTGCGCCCTCTCCGGTACGCTTAATCAACTGGTATTAGCGCGAGTTTT
ACAAGGCGTAGGCGGCGCGATGATGGTGCCGGTCGGACGCCTGACGGTCATGAAAATCGTGCCGCGTGCGCAATATATGG
CGGCGATGACCTTCGTCGCCCTACCGGGACAGATCGGGCCGTTACTCGGCCCCGCGCTGGGCGGGGTGCTGGTGGAATAT
GCTTCATGGCACTGGATCTTTCTGATCAATATCCCGGTGGGAATTGTCGGCGCTATGGCGACCTTTATGCTGATGCCAAA
CTACACCATAGAGACCCGGCGCTTTGATCTGCCGGGGTTCCTGCTGTTAGCTATCGGCATGGCGGTACTCACGCTGGCGC
TGGACGGTAGTAAAAGCATGGGGATTTCGCCCTGGACATTAGCCGGACTTGCTGCGGGTGGCGCGGCAGCCATTCTGCTC
TATCTCTTCCATGCCAAAAAAAACTCAGGTGCGTTATTCAGCCTGCGATTGTTCCGCACGCCCACGTTTTCACTGGGGTT
GCTGGGCAGTTTTGCCGGGCGTATCGGCAGCGGTATGCTGCCGTTTATGACGCCGGTCTTTTTACAAATTGGTCTTGGTT
TTTCACCGTTTCATGCCGGTTTGATGATGATCCCCATGGTGCTGGGCAGCATGGGAATGAAGCGGATTGTGGTGCAGATA
GTTAACCGTTTTGGCTATCGTCGGGTTCTGGTAGCGACCACGCTCGGACTGGCATTGGTTAGCCTGTTGTTTATGTCGGT
CGCGCTGCTCGGCTGGTATTATCTCCTGCCGCTGGTACTGCTTTTGCAGGGAATGGTGAACTCGGCGCGCTTTTCTTCCA
TGAATACCTTAACGCTAAAAGACCTTCCCGATACGCTGGCCAGCAGCGGCAATAGCTTATTATCGATGATTATGCAGCTC
TCGATGAGTATTGGCGTCACTATTGCCGGAATGCTGCTGGGTATGTTTGGCCAACAGCATATCGGGATAGACAGTAGCGC
CACACATCACGTCTTTATGTACACCTGGTTATGTATGGCGGTTATTATCGCGCTACCGGCGATAATTTTTGCCCGCGTGC
CGAACGATACACAGCAAAACATGGTCATTTCACGGCGTAAAAGGAGCCTGTAA

Upstream 100 bases:

>100_bases
GCCAGCTCCTGACGCTCTATACCACGCCGGTGGTGTACCTCTTTTTCGACCGTCTGCGGCTGCGTTTTTCGCGTAAAAAT
AGCAAACCGGTAGTAGAGAT

Downstream 100 bases:

>100_bases
TGAAAGTCTGGCGGCCCGGAATCACCGGCAAGCTGTTTCTGGCGATTTTCGCCACCTGCATCGTGCTGCTGATCAGTATG
CATTGGGCCGTGCGCGTCAG

Product: multidrug efflux system protein MdtE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTEFPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAVMLPASGWLADKIGVRNIFFA
AIVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGRLTVMKIVPRAQYMAAMTFVALPGQIGPLLGPALGGVLVEY
ASWHWIFLINIPVGIVGAMATFMLMPNYTIETRRFDLPGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILL
YLFHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQI
VNRFGYRRVLVATTLGLALVSLLFMSVALLGWYYLLPLVLLLQGMVNSARFSSMNTLTLKDLPDTLASSGNSLLSMIMQL
SMSIGVTIAGMLLGMFGQQHIGIDSSATHHVFMYTWLCMAVIIALPAIIFARVPNDTQQNMVISRRKRSL

Sequences:

>Translated_470_residues
MTEFPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAVMLPASGWLADKIGVRNIFFA
AIVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGRLTVMKIVPRAQYMAAMTFVALPGQIGPLLGPALGGVLVEY
ASWHWIFLINIPVGIVGAMATFMLMPNYTIETRRFDLPGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILL
YLFHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQI
VNRFGYRRVLVATTLGLALVSLLFMSVALLGWYYLLPLVLLLQGMVNSARFSSMNTLTLKDLPDTLASSGNSLLSMIMQL
SMSIGVTIAGMLLGMFGQQHIGIDSSATHHVFMYTWLCMAVIIALPAIIFARVPNDTQQNMVISRRKRSL
>Mature_469_residues
TEFPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAVMLPASGWLADKIGVRNIFFAA
IVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGRLTVMKIVPRAQYMAAMTFVALPGQIGPLLGPALGGVLVEYA
SWHWIFLINIPVGIVGAMATFMLMPNYTIETRRFDLPGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILLY
LFHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQIV
NRFGYRRVLVATTLGLALVSLLFMSVALLGWYYLLPLVLLLQGMVNSARFSSMNTLTLKDLPDTLASSGNSLLSMIMQLS
MSIGVTIAGMLLGMFGQQHIGIDSSATHHVFMYTWLCMAVIIALPAIIFARVPNDTQQNMVISRRKRSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI1788392, Length=469, Percent_Identity=85.7142857142857, Blast_Score=774, Evalue=0.0,
Organism=Escherichia coli, GI1790195, Length=459, Percent_Identity=45.5337690631808, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI1789042, Length=401, Percent_Identity=27.6807980049875, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788710, Length=422, Percent_Identity=27.4881516587678, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87081983, Length=413, Percent_Identity=28.5714285714286, Blast_Score=131, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6322958, Length=174, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319770, Length=287, Percent_Identity=27.1777003484321, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321663, Length=150, Percent_Identity=30.6666666666667, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325455, Length=125, Percent_Identity=32, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323735, Length=164, Percent_Identity=28.0487804878049, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50785; Mature: 50654

Theoretical pI: Translated: 10.76; Mature: 10.76

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
7.2 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MLPASGWLADKIGVRNIFFAAIVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGR
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHH
LTVMKIVPRAQYMAAMTFVALPGQIGPLLGPALGGVLVEYASWHWIFLINIPVGIVGAMA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHH
TFMLMPNYTIETRRFDLPGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILL
HHHHCCCCEEECEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHH
YLFHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAG
HHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHH
LMMIPMVLGSMGMKRIVVQIVNRFGYRRVLVATTLGLALVSLLFMSVALLGWYYLLPLVL
HHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQGMVNSARFSSMNTLTLKDLPDTLASSGNSLLSMIMQLSMSIGVTIAGMLLGMFGQQH
HHHHHHHHHHHCCCCEEEHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IGIDSSATHHVFMYTWLCMAVIIALPAIIFARVPNDTQQNMVISRRKRSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TEFPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MLPASGWLADKIGVRNIFFAAIVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGR
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHH
LTVMKIVPRAQYMAAMTFVALPGQIGPLLGPALGGVLVEYASWHWIFLINIPVGIVGAMA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHH
TFMLMPNYTIETRRFDLPGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILL
HHHHCCCCEEECEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHH
YLFHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAG
HHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHH
LMMIPMVLGSMGMKRIVVQIVNRFGYRRVLVATTLGLALVSLLFMSVALLGWYYLLPLVL
HHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQGMVNSARFSSMNTLTLKDLPDTLASSGNSLLSMIMQLSMSIGVTIAGMLLGMFGQQH
HHHHHHHHHHHCCCCEEEHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IGIDSSATHHVFMYTWLCMAVIIALPAIIFARVPNDTQQNMVISRRKRSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA