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The map label for this gene is ubiG [H]

Identifier: 29141103

GI number: 29141103

Start: 666007

End: 666735

Strand: Reverse

Name: ubiG [H]

Synonym: t0588

Alternate gene names: 29141103

Gene position: 666735-666007 (Counterclockwise)

Preceding gene: 29141104

Following gene: 29141102

Centisome position: 13.91

GC content: 54.73

Gene sequence:

>729_bases
ATGAACACTGAAAAACCGTCGGTAGCTCACAACGTTGACCATAATGAAATCGCCAAATTCGAAGCCGTCGCGTCGCGCTG
GTGGGATCTGAAGGGCGAATTCAAGCCATTGCATCGCATCAACCCCCTACGCCTTGGCTACATTACTGAGCGCTCAGGCG
GCCTGTTCGGTAAAAAGGTGCTCGACGTCGGCTGTGGCGGCGGTATTCTGGCGGAGAGCATGGCGCGCGAAGGCGCTACC
GTTACCGGGCTGGATATGGGCTTTGAGCCTTTGCAGGTCGCCAAACTGCATGCGCTGGAAAGCGGCATTGAGGTAGAGTA
CGTGCAGGAGACGGTTGAGGAACATGCGGCAAAACACGCCCAGCAATACGACGTCGTCACCTGTATGGAAATGCTGGAGC
ACGTTCCCGATCCGCAATCGGTCGTCCACGCCTGCGCCCAACTGGTTAAACCCGGCGGCGAGGTGTTCTTCTCAACGTTG
AACCGCAATGGGAAATCCTGGCTGATGGCGGTCGTCGGCGCTGAGTATATTCTGCGCATGGTGCCAAAAGGCACGCACGA
CGTGAAGAAATTCATTAAGCCTGCTGAACTGTTAAGCTGGGTAGATGAAACCGTCCTGAAAGAGCAACATATCACCGGGC
TGCACTACAACCCGATAACCAATACTTTCAAACTCGGTCCCGGAGTAGACGTTAACTACATGTTGCATACCCGCGCTAAA
AAAGCCTGA

Upstream 100 bases:

>100_bases
CTTGCGCTGAAAGCGTAATAAAGACGGCAGTAGATATAACGCAGCGACTTTGCACCTGCTATACTGCCCCGATAGATCAA
TAGCGGAATCTCATGTACTC

Downstream 100 bases:

>100_bases
CATCAAAGAATTTTCCTATAAGGGTTGCGTTAGATCATCGGGCGCAACCTTTCTCTTCGATGAAAAAATCAGCATTCGAT
CAAATTTTGATTTTTTTATG

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNTEKPSVAHNVDHNEIAKFEAVASRWWDLKGEFKPLHRINPLRLGYITERSGGLFGKKVLDVGCGGGILAESMAREGAT
VTGLDMGFEPLQVAKLHALESGIEVEYVQETVEEHAAKHAQQYDVVTCMEMLEHVPDPQSVVHACAQLVKPGGEVFFSTL
NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLSWVDETVLKEQHITGLHYNPITNTFKLGPGVDVNYMLHTRAK
KA

Sequences:

>Translated_242_residues
MNTEKPSVAHNVDHNEIAKFEAVASRWWDLKGEFKPLHRINPLRLGYITERSGGLFGKKVLDVGCGGGILAESMAREGAT
VTGLDMGFEPLQVAKLHALESGIEVEYVQETVEEHAAKHAQQYDVVTCMEMLEHVPDPQSVVHACAQLVKPGGEVFFSTL
NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLSWVDETVLKEQHITGLHYNPITNTFKLGPGVDVNYMLHTRAK
KA
>Mature_242_residues
MNTEKPSVAHNVDHNEIAKFEAVASRWWDLKGEFKPLHRINPLRLGYITERSGGLFGKKVLDVGCGGGILAESMAREGAT
VTGLDMGFEPLQVAKLHALESGIEVEYVQETVEEHAAKHAQQYDVVTCMEMLEHVPDPQSVVHACAQLVKPGGEVFFSTL
NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLSWVDETVLKEQHITGLHYNPITNTFKLGPGVDVNYMLHTRAK
KA

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=236, Percent_Identity=35.1694915254237, Blast_Score=161, Evalue=4e-40,
Organism=Escherichia coli, GI1788564, Length=240, Percent_Identity=92.0833333333333, Blast_Score=462, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI115533050, Length=239, Percent_Identity=31.7991631799163, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324476, Length=252, Percent_Identity=30.5555555555556, Blast_Score=122, Evalue=4e-29,
Organism=Drosophila melanogaster, GI281365311, Length=244, Percent_Identity=34.0163934426229, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24585589, Length=242, Percent_Identity=33.8842975206612, Blast_Score=141, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 26853; Mature: 26853

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTEKPSVAHNVDHNEIAKFEAVASRWWDLKGEFKPLHRINPLRLGYITERSGGLFGKKV
CCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEEECCCCCCHHHHH
LDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIEVEYVQETVEEHAAKHA
HHCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QQYDVVTCMEMLEHVPDPQSVVHACAQLVKPGGEVFFSTLNRNGKSWLMAVVGAEYILRM
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VPKGTHDVKKFIKPAELLSWVDETVLKEQHITGLHYNPITNTFKLGPGVDVNYMLHTRAK
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEECCCCCCEECCCCCCEEEEECCCCC
KA
CC
>Mature Secondary Structure
MNTEKPSVAHNVDHNEIAKFEAVASRWWDLKGEFKPLHRINPLRLGYITERSGGLFGKKV
CCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEEECCCCCCHHHHH
LDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIEVEYVQETVEEHAAKHA
HHCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QQYDVVTCMEMLEHVPDPQSVVHACAQLVKPGGEVFFSTLNRNGKSWLMAVVGAEYILRM
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VPKGTHDVKKFIKPAELLSWVDETVLKEQHITGLHYNPITNTFKLGPGVDVNYMLHTRAK
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEECCCCCCEECCCCCCEEEEECCCCC
KA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA