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The map label for this gene is arnT [H]

Identifier: 29141077

GI number: 29141077

Start: 636507

End: 638153

Strand: Reverse

Name: arnT [H]

Synonym: t0562

Alternate gene names: 29141077

Gene position: 638153-636507 (Counterclockwise)

Preceding gene: 29141078

Following gene: 29141076

Centisome position: 13.32

GC content: 54.28

Gene sequence:

>1647_bases
ATGATGAAATCGATACGCTATTATCTGGCTTTCGCCGCGTTTATCGCGCTCTACTATGTTATTCCTGTCAACAGCCGCCT
GCTCTGGCAGCCGGATGAAACGCGCTATGCCGAAATAAGTCGGGAGATGCTGGCGTCTGGCGACTGGATCGTGCCGCATT
TTCTGGGATTACGTTATTTTGAAAAACCGATAGCCGGTTACTGGATAAACAGTCTGGGTCAGTGGCTTTTTGGCGCTACC
AATTTTGGCGTGCGGGCCGGCGCTATTTTAACGACATTGCTGGCCGCAGCGCTGGTGGCGTGGCTGACGTTCCGCTTATG
GCGGGATAAACGTACCGCGTTGCTCGCCTCCGTGATCTTTCTCTCCCTCTTTGCCGTTTACAGTATCGGGACGTATGCGG
TACTCGACCCGATGATCGCGCTTTGGCTTACGGCCGGGATGTGTTGTTTCTGGCAGGGGATGCAGGCCACGACCCGAACG
GGCAAGATTGGGATGTTTTTGCTACTGGGCGCAACCTGCGGTCTGGGTGTATTAACTAAAGGGTTCCTCGCCCTGGCCGT
ACCGGTGGTGAGCGTGCTGCCGTGGGTTATTGTTCAGAAACGCTGGAAGGACTTTTTGCTTTACGGCTGGCTGGCGGTCT
TGAGCTGCTTTGTGGTTGTCCTTCCCTGGGCGATCGCCATTGCGCGACGCGAAGCCGATTTCTGGCATTACTTTTTCTGG
GTGGAGCATATCCAGCGATTCGCCATGAGCGATGCCCAGCATAAAGCCCCTTTCTGGTACTATCTGCCGGTGCTGCTCGC
GGGAAGTTTACCGTGGCTGGGGTTACTGCCTGGCGCGCTTAAACTGGGCTGGCGCGAGCGAAACGGCGCATTCTATTTGC
TCGGATGGACGATCATGCCGCTTCTCTTTTTCAGCATTGCGAAAGGGAAACTGCCCACCTATGTTCTTTCCTGTTTCGCA
CCGATAGCGATACTCATGGCGCGCTTCGTCCTGCATAACGTAAAAGAAGGCGTCGCCGCGCTACGTGTCAACGGCGGGAT
CAACCTGGTGTTCGGGATAATCGGGATCGTCGCGGCGTTTGTCGTCTCCTCATGGGGCCCGCTGAAATCGCCGGTGTGGA
CGCATATCGAAACCTATAAAGTGTTTTGCGTCTGGGGCGTCTTTACTGTTTGGGCGTTTGTGGGCTGGTATAGCCTCTGT
CATAGCCCAAAATACCTATTACCCGCGTTTTGTCCGCTGGGACTGGCGCTGCTGTTCGGCTTTTCCGTCCCCGACAGGGT
GATGGAGTCCAAACAGCCACAGTTTTTTGTCGAAATGACCCAGGCGCCTTTGGCATCAAGCCGCTATATTCTTGCCGACA
GCGTGGGCGTCGCCGCCGGGCTGGCCTGGAGTCTGAAACGAGACGATATTATGCTCTACGGACACGCGGGCGAACTCAGG
TATGGTCTTAGCTATCCTGATGTACAGAATAAATTCGTTAAAGCCGACGATTTTAACGCCTGGCTCAACCAACATCGTCA
GGAGGGCATTATTACGCTAGTACTTTCAATAGACAAAGACGAAGACATCAGCGCACTTTCCCTTCCCCCTGCGGACAATG
TTGATTATCAGGGGCGTCTGGTGTTAATTCAGTATCGGCCTAAATGA

Upstream 100 bases:

>100_bases
TGCCGGCATCGCCTGAGTCTCTGCCGTTGGGGCAAATTGTACGTGGACACATCCCTGGCCGTGAAGGTTGGCTGGGGTGT
CAACAGGCAGTGAGCGCCTC

Downstream 100 bases:

>100_bases
TCGGCATCGTTCTGGTGCTTGCCAGTCTGCTCAGCGTTGGCGGTCAGCTCTGCCAGAAGCAAGCGACACGGCCATTGACG
ACGGGCGGACGCCGCCGTCA

Product: 4-amino-4-deoxy-L-arabinose transferase

Products: NA

Alternate protein names: 4-amino-4-deoxy-L-arabinose lipid A transferase; Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase; Undecaprenyl phosphate-alpha-L-Ara4N transferase [H]

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MMKSIRYYLAFAAFIALYYVIPVNSRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPIAGYWINSLGQWLFGAT
NFGVRAGAILTTLLAAALVAWLTFRLWRDKRTALLASVIFLSLFAVYSIGTYAVLDPMIALWLTAGMCCFWQGMQATTRT
GKIGMFLLLGATCGLGVLTKGFLALAVPVVSVLPWVIVQKRWKDFLLYGWLAVLSCFVVVLPWAIAIARREADFWHYFFW
VEHIQRFAMSDAQHKAPFWYYLPVLLAGSLPWLGLLPGALKLGWRERNGAFYLLGWTIMPLLFFSIAKGKLPTYVLSCFA
PIAILMARFVLHNVKEGVAALRVNGGINLVFGIIGIVAAFVVSSWGPLKSPVWTHIETYKVFCVWGVFTVWAFVGWYSLC
HSPKYLLPAFCPLGLALLFGFSVPDRVMESKQPQFFVEMTQAPLASSRYILADSVGVAAGLAWSLKRDDIMLYGHAGELR
YGLSYPDVQNKFVKADDFNAWLNQHRQEGIITLVLSIDKDEDISALSLPPADNVDYQGRLVLIQYRPK

Sequences:

>Translated_548_residues
MMKSIRYYLAFAAFIALYYVIPVNSRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPIAGYWINSLGQWLFGAT
NFGVRAGAILTTLLAAALVAWLTFRLWRDKRTALLASVIFLSLFAVYSIGTYAVLDPMIALWLTAGMCCFWQGMQATTRT
GKIGMFLLLGATCGLGVLTKGFLALAVPVVSVLPWVIVQKRWKDFLLYGWLAVLSCFVVVLPWAIAIARREADFWHYFFW
VEHIQRFAMSDAQHKAPFWYYLPVLLAGSLPWLGLLPGALKLGWRERNGAFYLLGWTIMPLLFFSIAKGKLPTYVLSCFA
PIAILMARFVLHNVKEGVAALRVNGGINLVFGIIGIVAAFVVSSWGPLKSPVWTHIETYKVFCVWGVFTVWAFVGWYSLC
HSPKYLLPAFCPLGLALLFGFSVPDRVMESKQPQFFVEMTQAPLASSRYILADSVGVAAGLAWSLKRDDIMLYGHAGELR
YGLSYPDVQNKFVKADDFNAWLNQHRQEGIITLVLSIDKDEDISALSLPPADNVDYQGRLVLIQYRPK
>Mature_548_residues
MMKSIRYYLAFAAFIALYYVIPVNSRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPIAGYWINSLGQWLFGAT
NFGVRAGAILTTLLAAALVAWLTFRLWRDKRTALLASVIFLSLFAVYSIGTYAVLDPMIALWLTAGMCCFWQGMQATTRT
GKIGMFLLLGATCGLGVLTKGFLALAVPVVSVLPWVIVQKRWKDFLLYGWLAVLSCFVVVLPWAIAIARREADFWHYFFW
VEHIQRFAMSDAQHKAPFWYYLPVLLAGSLPWLGLLPGALKLGWRERNGAFYLLGWTIMPLLFFSIAKGKLPTYVLSCFA
PIAILMARFVLHNVKEGVAALRVNGGINLVFGIIGIVAAFVVSSWGPLKSPVWTHIETYKVFCVWGVFTVWAFVGWYSLC
HSPKYLLPAFCPLGLALLFGFSVPDRVMESKQPQFFVEMTQAPLASSRYILADSVGVAAGLAWSLKRDDIMLYGHAGELR
YGLSYPDVQNKFVKADDFNAWLNQHRQEGIITLVLSIDKDEDISALSLPPADNVDYQGRLVLIQYRPK

Specific function: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG1807

COG function: function code M; 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 83 family [H]

Homologues:

Organism=Escherichia coli, GI1788591, Length=550, Percent_Identity=71.2727272727273, Blast_Score=825, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022839
- InterPro:   IPR003342 [H]

Pfam domain/function: PF02366 PMT [H]

EC number: =2.4.2.43 [H]

Molecular weight: Translated: 61763; Mature: 61763

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEECCC
>Mature Secondary Structure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EEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA