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The map label for this gene is pgtA [H]

Identifier: 29140983

GI number: 29140983

Start: 536267

End: 537514

Strand: Direct

Name: pgtA [H]

Synonym: t0462

Alternate gene names: 29140983

Gene position: 536267-537514 (Clockwise)

Preceding gene: 29140982

Following gene: 29140984

Centisome position: 11.19

GC content: 51.92

Gene sequence:

>1248_bases
ATGTTGAATGATGAATGTTCTATTTTGCTGATTGATGATGACGTTGATGTACTTGACGCCTATACCCAAATGCTTGAGCA
GGCAGGCTACCGCGTGCGTGGCTTTACCCATCCTTTCGAGGCCAAAGAGTGGGTAAAAGCGGATTGGGAGGGGATCGTTT
TGAGCGATGTGTGTATGCCGGGGTGTTCCGGTATCGATCTTATGACGCTGTTTCATCAGGATGACGATCAACTGCCAATC
TTATTGATTACCGGACATGGCGATGTACCGATGGCGGTTGATGCGGTGAAAAAGGGCGCCTGGGATTTTCTGCAAAAACC
CGTCGATCCGGGCAAACTGTTGATATTAATTGAAGACGCGCTACGCCAGCGCCGGTCGGTTATTGCACGGCGGCAATATT
GCCAGCAGACGTTACAGGTTGACCTGATTGGGCGCAGCGAGTGGATGAATCAGTTTCGACAACGGTTACAACAACTGGCG
GAAACGGACATTGCCGTATGGTTTTACGGTGAGCATGACACAGGACGTATGACTGGCGCCCGTTATCTCCATCAGCTGGG
GCGTAACGCGAAAGGGCCGTTTGTTCGCTATGAACTCACGCCGGAGAATGCCGGGCAGTTGGAGACATTCATCGACCAGG
CGCAAGGAGGCACGCTGGTGTTGAGTTATCCCGAATATCTGACACGCGAACAGCAGCACCATCTGGCGCGTTTACAAAGC
CTGGAGCATCGGCCTTTTCGTTTGGTGGGCGTTGGCAGCGCTTCGCTGGTGGAGCAGGCGGCAGCTAACCAGATAGCGGC
CGAGCTTTACTACTGTTTCGCCATGACCCAAATCGCCTGCCAGTCTCTTTCTCAGCGACCGGATGATATCGAGCCGTTAT
TTCGCCATTATCTTCGAAAAGCCTGCCTGCGACTCAATCATCCAGTGCCGGAAATAGCGGGGGAATTACTGAAAGGAATA
ATGCGACGCGCCTGGCCAAGCAATGTGCGCGAACTGGCCAATGCGGCGGAGCTTTTTGCTGTCGGCGTGCTGCCGCTGGC
GGAAACGGTCAACCCGCAGTTGCTTCTGCAGGAGCCGACCCCGCTTGACCGGCGCGTTGAAGAGTATGAGCGACAAATTA
TTACCGAAGCATTAAATATTCATCAGGGACGAATTAATGAAGTGGCGGAGTACTTGCAAATTCCCCGTAAAAAACTTTAT
CTGCGCATGAAAAAATATGGTCTAAGTAAAGAGCATTATAAATTCTGA

Upstream 100 bases:

>100_bases
GTGTCGCTGATGGCGCAAATGAAGGGCGACCTGCGTCTGGCGTCGACGCTGACGCGTAATGCTTGCGTGGTGCTGCAATT
CTCGGTAACGGATGTCGATG

Downstream 100 bases:

>100_bases
TATTACAGTTACTTTCAATCTGGCTGACAACAACAGCAACGATGTCGTTAGCCAGATAACGTCGCATTACCGTAATGGTA
AATCATTCCATTATGATTAT

Product: phosphoglycerate transport system transcriptional regulator PgtA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MLNDECSILLIDDDVDVLDAYTQMLEQAGYRVRGFTHPFEAKEWVKADWEGIVLSDVCMPGCSGIDLMTLFHQDDDQLPI
LLITGHGDVPMAVDAVKKGAWDFLQKPVDPGKLLILIEDALRQRRSVIARRQYCQQTLQVDLIGRSEWMNQFRQRLQQLA
ETDIAVWFYGEHDTGRMTGARYLHQLGRNAKGPFVRYELTPENAGQLETFIDQAQGGTLVLSYPEYLTREQQHHLARLQS
LEHRPFRLVGVGSASLVEQAAANQIAAELYYCFAMTQIACQSLSQRPDDIEPLFRHYLRKACLRLNHPVPEIAGELLKGI
MRRAWPSNVRELANAAELFAVGVLPLAETVNPQLLLQEPTPLDRRVEEYERQIITEALNIHQGRINEVAEYLQIPRKKLY
LRMKKYGLSKEHYKF

Sequences:

>Translated_415_residues
MLNDECSILLIDDDVDVLDAYTQMLEQAGYRVRGFTHPFEAKEWVKADWEGIVLSDVCMPGCSGIDLMTLFHQDDDQLPI
LLITGHGDVPMAVDAVKKGAWDFLQKPVDPGKLLILIEDALRQRRSVIARRQYCQQTLQVDLIGRSEWMNQFRQRLQQLA
ETDIAVWFYGEHDTGRMTGARYLHQLGRNAKGPFVRYELTPENAGQLETFIDQAQGGTLVLSYPEYLTREQQHHLARLQS
LEHRPFRLVGVGSASLVEQAAANQIAAELYYCFAMTQIACQSLSQRPDDIEPLFRHYLRKACLRLNHPVPEIAGELLKGI
MRRAWPSNVRELANAAELFAVGVLPLAETVNPQLLLQEPTPLDRRVEEYERQIITEALNIHQGRINEVAEYLQIPRKKLY
LRMKKYGLSKEHYKF
>Mature_415_residues
MLNDECSILLIDDDVDVLDAYTQMLEQAGYRVRGFTHPFEAKEWVKADWEGIVLSDVCMPGCSGIDLMTLFHQDDDQLPI
LLITGHGDVPMAVDAVKKGAWDFLQKPVDPGKLLILIEDALRQRRSVIARRQYCQQTLQVDLIGRSEWMNQFRQRLQQLA
ETDIAVWFYGEHDTGRMTGARYLHQLGRNAKGPFVRYELTPENAGQLETFIDQAQGGTLVLSYPEYLTREQQHHLARLQS
LEHRPFRLVGVGSASLVEQAAANQIAAELYYCFAMTQIACQSLSQRPDDIEPLFRHYLRKACLRLNHPVPEIAGELLKGI
MRRAWPSNVRELANAAELFAVGVLPLAETVNPQLLLQEPTPLDRRVEEYERQIITEALNIHQGRINEVAEYLQIPRKKLY
LRMKKYGLSKEHYKF

Specific function: Member of the two-component regulatory system pgtB/pgtA that regulates the inducible phosphoglycerate transport system. When activated by pgtB it acts in conjunction with sigma-54 as a transcriptional activator [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=446, Percent_Identity=26.6816143497758, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1790299, Length=469, Percent_Identity=24.9466950959488, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788905, Length=450, Percent_Identity=26.2222222222222, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788550, Length=455, Percent_Identity=23.7362637362637, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1789233, Length=320, Percent_Identity=26.5625, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789087, Length=314, Percent_Identity=28.6624203821656, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082117, Length=322, Percent_Identity=25.4658385093168, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87081858, Length=299, Percent_Identity=24.7491638795987, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787583, Length=308, Percent_Identity=24.025974025974, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 47596; Mature: 47596

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNDECSILLIDDDVDVLDAYTQMLEQAGYRVRGFTHPFEAKEWVKADWEGIVLSDVCMP
CCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHCCCCCEEEHHHHCC
GCSGIDLMTLFHQDDDQLPILLITGHGDVPMAVDAVKKGAWDFLQKPVDPGKLLILIEDA
CCCCCHHHEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEHHH
LRQRRSVIARRQYCQQTLQVDLIGRSEWMNQFRQRLQQLAETDIAVWFYGEHDTGRMTGA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHH
RYLHQLGRNAKGPFVRYELTPENAGQLETFIDQAQGGTLVLSYPEYLTREQQHHLARLQS
HHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHH
LEHRPFRLVGVGSASLVEQAAANQIAAELYYCFAMTQIACQSLSQRPDDIEPLFRHYLRK
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ACLRLNHPVPEIAGELLKGIMRRAWPSNVRELANAAELFAVGVLPLAETVNPQLLLQEPT
HHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
PLDRRVEEYERQIITEALNIHQGRINEVAEYLQIPRKKLYLRMKKYGLSKEHYKF
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLNDECSILLIDDDVDVLDAYTQMLEQAGYRVRGFTHPFEAKEWVKADWEGIVLSDVCMP
CCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHCCCCCEEEHHHHCC
GCSGIDLMTLFHQDDDQLPILLITGHGDVPMAVDAVKKGAWDFLQKPVDPGKLLILIEDA
CCCCCHHHEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEHHH
LRQRRSVIARRQYCQQTLQVDLIGRSEWMNQFRQRLQQLAETDIAVWFYGEHDTGRMTGA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHH
RYLHQLGRNAKGPFVRYELTPENAGQLETFIDQAQGGTLVLSYPEYLTREQQHHLARLQS
HHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHH
LEHRPFRLVGVGSASLVEQAAANQIAAELYYCFAMTQIACQSLSQRPDDIEPLFRHYLRK
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ACLRLNHPVPEIAGELLKGIMRRAWPSNVRELANAAELFAVGVLPLAETVNPQLLLQEPT
HHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
PLDRRVEEYERQIITEALNIHQGRINEVAEYLQIPRKKLYLRMKKYGLSKEHYKF
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3023201; 11677609; 2842311 [H]