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The map label for this gene is gntP [C]

Identifier: 29140893

GI number: 29140893

Start: 435969

End: 437237

Strand: Direct

Name: gntP [C]

Synonym: t0366

Alternate gene names: 29140893

Gene position: 435969-437237 (Clockwise)

Preceding gene: 29140892

Following gene: 29140894

Centisome position: 9.1

GC content: 56.26

Gene sequence:

>1269_bases
ATGACGTCGATATCCACCTTGGGAGCCATTGCCGCATTGGTTGTGGCCATCGTATTAATTTTAAGAAAAGTGTCGCCAGC
CTACGGCATGATGGCGGGCGCGCTGGTCGGCGGTTTGATTGGCGGCGCCGATCTTCTGCAAACCGTGTCGCTGATGGTGT
CAGGCGCGCAGGGCATCGTTAATGCCGTATTGCGTATTCTGGCCGCAGGCGTACTGGCGGGCGTATTAATTGAGTCCGGG
GCGGCGAATACGATTGCTGAGACGATTGTCCGCAAAGTGGGGGAAACCCGGGCATTATTGGCATTAGCCATTGCCACACT
ATGTTTGACCGCCGTCGGCGTATTTATTGATGTGGCGGTGATTACCGTCGCGCCGATTGCGCTGTCGATTGCGCGTAATG
CAGGCCTGTCAAAAAGCGCTATTCTGCTGGCGATGGTCGGCGGCGGCAAAGCGGGTAACGTGATGTCACCTAACCCGAAC
GCTATTGCCGCCTCCGATGCGTTTCATGTTCCTCTTACCTCTATTATGCTGGCGGGCGTGGTTCCGGGCATCGTTGGGCT
TATTATCGCCTATCTGTTAGCGAAACGGCTGAATAATAAAGGCGCGGGCGTCGCCGATCATGAAGTGACTCACCATGATG
ACTCTGTCGCCAGGCCCGGTTTTCTGGTGGCGATTAGCGCGCCGCTGGTCGCTATTTTCCTGCTTTCTCTCCGTCCGTTT
GTCGGCATTTCCATTGACCCGTTAATTGCCCTGCCCGTAGGGGGATTGGTCGGTCTGCTGTTGATGGGACGCGCGCGCCA
CTGTAACCAGTACATGGTCGCCGGTCTGATGCGTATGGCGCCTGTCGCTATTATGTTGCTGGGAACCGGTACGCTGGCCG
GCATTATCGCTAATTCCGAACTTAAAGATGTCCTGATTCATGGCCTCACCGCTTCGGGATTGCCGTCCTGGCTGCTGGCG
CCCGTGTCTGGCGCCATGATGTCAATGGCGACGGCCTCAACCACAGCGGGAACGGCGGTGGCGTCCGGCGTTTTCTCTCC
CACGTTACTTGAACTTGGCGTTTCCGCCCTGGCGGGAGCCGCTATGATCCATGCGGGCGCCACGGTGCTGGACCATCTGC
CGCATGGCAGCTTTTTCCACGCGACGGGCGGCAGCGTCAATATGCAAATTCATGAACGTTTAAAGCTAATGCCGTATGAA
ACGCTGGTGGGGTTAGCCATTACCTTTATTTCTACTCTGATGTTCGGTTTCTTTGGTTTTGCAGGATAA

Upstream 100 bases:

>100_bases
TTACCGCTGCCTGGTCGAATCGAAATTTGTTGAAAGCTCCAGCGGATTTTTAGGCGGTTTTTTCCATACTGCGCGCTCCA
TGTTAAAGGAGGCGCAGTAT

Downstream 100 bases:

>100_bases
TCCCTATGAAAATTGTTATTGCTCCTGATTCATTTAAAGAAAGTTTGTCCGCAATGGCGGTCGCTGAGGCGATAGAAAAG
GGGTTCCGCGAAATTTATCC

Product: permease

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MTSISTLGAIAALVVAIVLILRKVSPAYGMMAGALVGGLIGGADLLQTVSLMVSGAQGIVNAVLRILAAGVLAGVLIESG
AANTIAETIVRKVGETRALLALAIATLCLTAVGVFIDVAVITVAPIALSIARNAGLSKSAILLAMVGGGKAGNVMSPNPN
AIAASDAFHVPLTSIMLAGVVPGIVGLIIAYLLAKRLNNKGAGVADHEVTHHDDSVARPGFLVAISAPLVAIFLLSLRPF
VGISIDPLIALPVGGLVGLLLMGRARHCNQYMVAGLMRMAPVAIMLLGTGTLAGIIANSELKDVLIHGLTASGLPSWLLA
PVSGAMMSMATASTTAGTAVASGVFSPTLLELGVSALAGAAMIHAGATVLDHLPHGSFFHATGGSVNMQIHERLKLMPYE
TLVGLAITFISTLMFGFFGFAG

Sequences:

>Translated_422_residues
MTSISTLGAIAALVVAIVLILRKVSPAYGMMAGALVGGLIGGADLLQTVSLMVSGAQGIVNAVLRILAAGVLAGVLIESG
AANTIAETIVRKVGETRALLALAIATLCLTAVGVFIDVAVITVAPIALSIARNAGLSKSAILLAMVGGGKAGNVMSPNPN
AIAASDAFHVPLTSIMLAGVVPGIVGLIIAYLLAKRLNNKGAGVADHEVTHHDDSVARPGFLVAISAPLVAIFLLSLRPF
VGISIDPLIALPVGGLVGLLLMGRARHCNQYMVAGLMRMAPVAIMLLGTGTLAGIIANSELKDVLIHGLTASGLPSWLLA
PVSGAMMSMATASTTAGTAVASGVFSPTLLELGVSALAGAAMIHAGATVLDHLPHGSFFHATGGSVNMQIHERLKLMPYE
TLVGLAITFISTLMFGFFGFAG
>Mature_421_residues
TSISTLGAIAALVVAIVLILRKVSPAYGMMAGALVGGLIGGADLLQTVSLMVSGAQGIVNAVLRILAAGVLAGVLIESGA
ANTIAETIVRKVGETRALLALAIATLCLTAVGVFIDVAVITVAPIALSIARNAGLSKSAILLAMVGGGKAGNVMSPNPNA
IAASDAFHVPLTSIMLAGVVPGIVGLIIAYLLAKRLNNKGAGVADHEVTHHDDSVARPGFLVAISAPLVAIFLLSLRPFV
GISIDPLIALPVGGLVGLLLMGRARHCNQYMVAGLMRMAPVAIMLLGTGTLAGIIANSELKDVLIHGLTASGLPSWLLAP
VSGAMMSMATASTTAGTAVASGVFSPTLLELGVSALAGAAMIHAGATVLDHLPHGSFFHATGGSVNMQIHERLKLMPYET
LVGLAITFISTLMFGFFGFAG

Specific function: High-Affinity Gluconate Transporter With Fairly Broad Specificity, Including Low Affinity For Glucuronate, Several Disaccharides, And Some Hexoses, But Not Glucose. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Escherichia coli, GI1790776, Length=436, Percent_Identity=25, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 42517; Mature: 42386

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSISTLGAIAALVVAIVLILRKVSPAYGMMAGALVGGLIGGADLLQTVSLMVSGAQGIV
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCHHHHH
NAVLRILAAGVLAGVLIESGAANTIAETIVRKVGETRALLALAIATLCLTAVGVFIDVAV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
ITVAPIALSIARNAGLSKSAILLAMVGGGKAGNVMSPNPNAIAASDAFHVPLTSIMLAGV
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHH
VPGIVGLIIAYLLAKRLNNKGAGVADHEVTHHDDSVARPGFLVAISAPLVAIFLLSLRPF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHH
VGISIDPLIALPVGGLVGLLLMGRARHCNQYMVAGLMRMAPVAIMLLGTGTLAGIIANSE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCH
LKDVLIHGLTASGLPSWLLAPVSGAMMSMATASTTAGTAVASGVFSPTLLELGVSALAGA
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHH
AMIHAGATVLDHLPHGSFFHATGGSVNMQIHERLKLMPYETLVGLAITFISTLMFGFFGF
HHHHHHHHHHHHCCCCCEEECCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
AG
CC
>Mature Secondary Structure 
TSISTLGAIAALVVAIVLILRKVSPAYGMMAGALVGGLIGGADLLQTVSLMVSGAQGIV
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCHHHHH
NAVLRILAAGVLAGVLIESGAANTIAETIVRKVGETRALLALAIATLCLTAVGVFIDVAV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
ITVAPIALSIARNAGLSKSAILLAMVGGGKAGNVMSPNPNAIAASDAFHVPLTSIMLAGV
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHH
VPGIVGLIIAYLLAKRLNNKGAGVADHEVTHHDDSVARPGFLVAISAPLVAIFLLSLRPF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHH
VGISIDPLIALPVGGLVGLLLMGRARHCNQYMVAGLMRMAPVAIMLLGTGTLAGIIANSE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCH
LKDVLIHGLTASGLPSWLLAPVSGAMMSMATASTTAGTAVASGVFSPTLLELGVSALAGA
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHH
AMIHAGATVLDHLPHGSFFHATGGSVNMQIHERLKLMPYETLVGLAITFISTLMFGFFGF
HHHHHHHHHHHHCCCCCEEECCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]