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The map label for this gene is engA [H]

Identifier: 29140869

GI number: 29140869

Start: 387670

End: 389142

Strand: Direct

Name: engA [H]

Synonym: t0337

Alternate gene names: 29140869

Gene position: 387670-389142 (Clockwise)

Preceding gene: 29140868

Following gene: 29140870

Centisome position: 8.09

GC content: 54.38

Gene sequence:

>1473_bases
ATGGTACCTGTGGTCGCGCTTGTCGGGCGCCCTAACGTCGGAAAATCCACGCTATTTAACCGTCTGACCCGCACCCGAGA
TGCGTTGGTTGCGGATTTCCCGGGTCTGACTCGTGACCGTAAGTACGGTCGTGCGGAGGTTGAAGGCCGCGAGTTTATCT
GTATCGACACCGGCGGTATTGACGGCACCGAAGACGGCGTCGAAACGCGGATGGCGGAACAGTCGCTGCTGGCGATTGAA
GAAGCGGATGTGGTGTTATTCATGGTAGATGCGCGCGCTGGTCTGATGCCGGCGGATGAAGCGATTGCCAAACATCTGCG
CTCCCGTGAAAAACCGACCTTCCTGGTGGCGAATAAAACGGATGGTCTCGATCCCGATCAGGCGGTTGTCGATTTTTACT
CGCTGGGATTAGGCGAAATTTATCCTATCGCCGCCTCACATGGTCGCGGCGTATTGAGCCTGCTGGAACATGTGCTTCTG
CCGTGGATGGATGATGTCGCACCGCAGGAAGAAGTGGATGAAGACGCGGAATACTGGGCGCAGTTCGAGGCGGAACAAAA
TGGCGAAGAAGCGCCGGAAGATGATTTTGACCCGCAAAGCCTGCCGATAAAGCTAGCGATTGTCGGTCGCCCGAACGTAG
GTAAGTCCACACTCACTAACCGTATTCTCGGCGAAGAGCGCGTGGTGGTATACGACATGCCGGGCACCACTCGCGACAGT
ATTTATATCCCGATGGAACGCGACGAACGGGAATATGTGCTGATTGACACGGCGGGGGTGCGTAAGCGCGGAAAAATCAC
CGATGCGGTAGAAAAGTTCTCGGTGATTAAAACGTTACAGGCGATTGAAGACGCTAACGTCGTACTGTTGGTTATCGATG
CGCGCGAGGGGATCTCTGACCAGGATTTGTCTCTGCTGGGCTTTATCCTCAATAGTGGGCGCTCACTCGTTATCGTAGTC
AACAAATGGGATGGCCTGAGCCAGGAAGTCAAAGAGCAGGTGAAAGAGACGCTGGATTTCCGTCTGGGCTTTATTGATTT
TGCCCGCGTGCACTTTATCTCTGCGCTGCACGGCAGCGGTGTCGGGAACCTGTTTGAGTCCGTACGCGAGGCTTACGACA
GTTCCACTCGCCGGGTGAGCACTGCGATGCTGACCCGTATCATGACGATGGCGGTGGAAGATCATCAGCCGCCGCTAGTG
CGCGGTCGCCGTGTGAAGCTGAAATATGCCCACACTGGCGGCTATAACCCGCCGATTGTGGTTATTCACGGCAACCAGGT
AAAAGATCTGCCAGACTCCTATAAGCGCTATCTGATGAACTACTTCCGCAAGTCGTTGGAAGTGATGGGTACGCCGATTC
GCATTCAGTTTAAAGAAGGGGAGAACCCGTATGCGAACAAGCGTAACACACTGACGCCAACGCAAATGCGCAAACGTAAG
CGTCTGATGAAGCATATCAAGAAAAGCAAGTAA

Upstream 100 bases:

>100_bases
TGAAAAAACGGCTCCTGGTGTAGGGGCCGTTTTCCTGTTTTTAACAACGGCGTAAAAATGACGCGCGTTGTCTGATGATT
TTTTAAATGAGGCTTTAAAC

Downstream 100 bases:

>100_bases
TGCTTTTTCAGTAATATTCCAGGCCTGATAAGCGCAGCGCTATCAGGCCTTTCAAGTAAAAGCGAGTCACGCGCCTGAGG
AGAATGTTATGGAAATAATC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVEGREFICIDTGGIDGTEDGVETRMAEQSLLAIE
EADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLL
PWMDDVAPQEEVDEDAEYWAQFEAEQNGEEAPEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDS
IYIPMERDEREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVIVV
NKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVSTAMLTRIMTMAVEDHQPPLV
RGRRVKLKYAHTGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLEVMGTPIRIQFKEGENPYANKRNTLTPTQMRKRK
RLMKHIKKSK

Sequences:

>Translated_490_residues
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVEGREFICIDTGGIDGTEDGVETRMAEQSLLAIE
EADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLL
PWMDDVAPQEEVDEDAEYWAQFEAEQNGEEAPEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDS
IYIPMERDEREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVIVV
NKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVSTAMLTRIMTMAVEDHQPPLV
RGRRVKLKYAHTGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLEVMGTPIRIQFKEGENPYANKRNTLTPTQMRKRK
RLMKHIKKSK
>Mature_490_residues
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVEGREFICIDTGGIDGTEDGVETRMAEQSLLAIE
EADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLL
PWMDDVAPQEEVDEDAEYWAQFEAEQNGEEAPEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDS
IYIPMERDEREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVIVV
NKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVSTAMLTRIMTMAVEDHQPPLV
RGRRVKLKYAHTGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLEVMGTPIRIQFKEGENPYANKRNTLTPTQMRKRK
RLMKHIKKSK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=490, Percent_Identity=97.1428571428571, Blast_Score=958, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=40.2173913043478, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=162, Percent_Identity=33.9506172839506, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 55003; Mature: 55003

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVEGREFICIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCC
DGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKT
CCCCHHHHHHHHHHHHHEEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECC
DGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMDDVAPQEEVDEDAEYWA
CCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHH
QFEAEQNGEEAPEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDS
HHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCC
IYIPMERDEREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVLLVIDAREGISD
EEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
QDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSG
CHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VGNLFESVREAYDSSTRRVSTAMLTRIMTMAVEDHQPPLVRGRRVKLKYAHTGGYNPPIV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCEE
VIHGNQVKDLPDSYKRYLMNYFRKSLEVMGTPIRIQFKEGENPYANKRNTLTPTQMRKRK
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHH
RLMKHIKKSK
HHHHHHHHCC
>Mature Secondary Structure
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVEGREFICIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCC
DGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKT
CCCCHHHHHHHHHHHHHEEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECC
DGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMDDVAPQEEVDEDAEYWA
CCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHH
QFEAEQNGEEAPEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDS
HHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCC
IYIPMERDEREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVLLVIDAREGISD
EEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
QDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSG
CHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VGNLFESVREAYDSSTRRVSTAMLTRIMTMAVEDHQPPLVRGRRVKLKYAHTGGYNPPIV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCEE
VIHGNQVKDLPDSYKRYLMNYFRKSLEVMGTPIRIQFKEGENPYANKRNTLTPTQMRKRK
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHH
RLMKHIKKSK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA