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The map label for this gene is cadC [H]

Identifier: 29140833

GI number: 29140833

Start: 342575

End: 344119

Strand: Reverse

Name: cadC [H]

Synonym: t0299

Alternate gene names: 29140833

Gene position: 344119-342575 (Counterclockwise)

Preceding gene: 29140834

Following gene: 29140832

Centisome position: 7.18

GC content: 47.64

Gene sequence:

>1545_bases
ATGCAGCAACCTGTTGTACGCATTGGAGAGTGGCTGGTTACACCTTCTGTTAATCAGATCAGTCGTCAGGGACGCCAGAT
TACTCTTGAACCACGGCTGATCGATCTTCTGATGTATTTTGCGCATCATCCGGATGAAGTGTTAAGCCGGGATAACATTA
TTGATCATGTCTGGATGCGCACCATCGTGACCAACCATGTTGTCACCCAAAGCATTTCTGAACTACGCAAATCATTAAGA
GATGGCGGAGACAGCAATGCTGAATACATCGTTACCGTACCTAAACGCGGCTATAAGCTGACGGCGCCGGTTATCTGGTG
CGAAGAAAATAGCGATGAGATCGATAATTTATCAACGTCGCCGCCGCCGCCGATCGCAGCGACGAATGCAGAACCGACAG
AGGGGGTTCCTGCCGCTGCGCCTGTGCCGCCCGCCTCTTTGCAAACGCCGACTAAAAAGGCGAAAAAGCCGCGTATCGCC
GCTTTCTGGACGTGGGTGATGTTCCTGCTCTCGCTGGCGACGCTGGTGGTGTTTATCGTGATGTCGGTGGTAGATCATAA
TGCCGCGGTAACAAAAACGCGGTTATTACTTAACCCACGAGATATAGATGTTCGTTTTGAAGGCGGCAATTCCTGTAATA
ACTGGGTCTCGCAGGAGTCCTACGCCATCGGTCTGGGCGGCTTAATCACCGACCTGCTGAACACCTACTCGACCTTTATG
GTGCACGATAAAACCAATTACCGGGTCAATGAGCCAAGCAACTCCGGTAAGACGTTAACCATTCAGTTTGTCAATCAGCG
CCACTATCGGGCGCAGCAGTGCTTTATGTCTGTGGTGCTCATTGATAACGCCGATGGTTCAACCATGCTGGATAAGCGTT
ATTTCGTCACCAATACTAACCAGTTGTCCATCCAGGATGATCTGTTTAATAGCCTGTCTTTCGTTTTAACACAGCCCTGG
CCTAATCGTATGCGAGAACAACTGGCCCTGTTCAGAACGCCGCAAAATACCGCGCTGATGCGTTTTTATGAGGCGCGCCA
GCTTATTCTGAGCGGCGATGCGCAGGCGCTAAGTAAAGCCGGCGATATTCTGAATGGCATTATTAAGGAAACGCCTGATT
TCAACTATGCCTATGAATATAAAGTGCTGGTAGATGTATTACGGCAATCACAACAGCCGTTTGATAAAGAACAAGTGGCT
GCGCTGAACGAAGAGTTTAAAAAAATAGATCAAATTCCGGGCGTTGAGAAAACGTCTGTTTATTATAAAATCAAGACCGT
TGATCTTTTGGGCAAAGGTGATATCGATGCAGCGTATGAGGAAATCAATAAAAGCATCGAGCTTGAAATGTCGTGGTTTA
ACTATGTCCTGTTGGGGAAAGTTTACGAAATGAAAGGTGAGAATCGTCTGGCCGCTGATGCCTATCTGACCGCCTTTAAT
TTACGTCCAGGTGAAAATACGCTGTACTGGATCGAGAACGGCGTATTTCAGACATCCGTTCAGAAAATTGTCCCTTATCT
GAATAGTTTTCTGGCAGAAGATTAA

Upstream 100 bases:

>100_bases
CTGCTTTTTATGCCTTTCTTTTACAAAAAAGGGGAATAAAAAAGTCTGTGCAAATCGTGTTATTATTAACGTTTGACTTA
GCTCGTTAGGGCATCTTTTT

Downstream 100 bases:

>100_bases
ATTTAACGCTGAACCATGACAAATAAAAGCGAAAAGATATTAAATTTTTCGCTTTTATTTTGTGAAAAATATGTTGCAAA
AAATAGCTTATGTTAATTTT

Product: DNA-binding transcriptional activator CadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MQQPVVRIGEWLVTPSVNQISRQGRQITLEPRLIDLLMYFAHHPDEVLSRDNIIDHVWMRTIVTNHVVTQSISELRKSLR
DGGDSNAEYIVTVPKRGYKLTAPVIWCEENSDEIDNLSTSPPPPIAATNAEPTEGVPAAAPVPPASLQTPTKKAKKPRIA
AFWTWVMFLLSLATLVVFIVMSVVDHNAAVTKTRLLLNPRDIDVRFEGGNSCNNWVSQESYAIGLGGLITDLLNTYSTFM
VHDKTNYRVNEPSNSGKTLTIQFVNQRHYRAQQCFMSVVLIDNADGSTMLDKRYFVTNTNQLSIQDDLFNSLSFVLTQPW
PNRMREQLALFRTPQNTALMRFYEARQLILSGDAQALSKAGDILNGIIKETPDFNYAYEYKVLVDVLRQSQQPFDKEQVA
ALNEEFKKIDQIPGVEKTSVYYKIKTVDLLGKGDIDAAYEEINKSIELEMSWFNYVLLGKVYEMKGENRLAADAYLTAFN
LRPGENTLYWIENGVFQTSVQKIVPYLNSFLAED

Sequences:

>Translated_514_residues
MQQPVVRIGEWLVTPSVNQISRQGRQITLEPRLIDLLMYFAHHPDEVLSRDNIIDHVWMRTIVTNHVVTQSISELRKSLR
DGGDSNAEYIVTVPKRGYKLTAPVIWCEENSDEIDNLSTSPPPPIAATNAEPTEGVPAAAPVPPASLQTPTKKAKKPRIA
AFWTWVMFLLSLATLVVFIVMSVVDHNAAVTKTRLLLNPRDIDVRFEGGNSCNNWVSQESYAIGLGGLITDLLNTYSTFM
VHDKTNYRVNEPSNSGKTLTIQFVNQRHYRAQQCFMSVVLIDNADGSTMLDKRYFVTNTNQLSIQDDLFNSLSFVLTQPW
PNRMREQLALFRTPQNTALMRFYEARQLILSGDAQALSKAGDILNGIIKETPDFNYAYEYKVLVDVLRQSQQPFDKEQVA
ALNEEFKKIDQIPGVEKTSVYYKIKTVDLLGKGDIDAAYEEINKSIELEMSWFNYVLLGKVYEMKGENRLAADAYLTAFN
LRPGENTLYWIENGVFQTSVQKIVPYLNSFLAED
>Mature_514_residues
MQQPVVRIGEWLVTPSVNQISRQGRQITLEPRLIDLLMYFAHHPDEVLSRDNIIDHVWMRTIVTNHVVTQSISELRKSLR
DGGDSNAEYIVTVPKRGYKLTAPVIWCEENSDEIDNLSTSPPPPIAATNAEPTEGVPAAAPVPPASLQTPTKKAKKPRIA
AFWTWVMFLLSLATLVVFIVMSVVDHNAAVTKTRLLLNPRDIDVRFEGGNSCNNWVSQESYAIGLGGLITDLLNTYSTFM
VHDKTNYRVNEPSNSGKTLTIQFVNQRHYRAQQCFMSVVLIDNADGSTMLDKRYFVTNTNQLSIQDDLFNSLSFVLTQPW
PNRMREQLALFRTPQNTALMRFYEARQLILSGDAQALSKAGDILNGIIKETPDFNYAYEYKVLVDVLRQSQQPFDKEQVA
ALNEEFKKIDQIPGVEKTSVYYKIKTVDLLGKGDIDAAYEEINKSIELEMSWFNYVLLGKVYEMKGENRLAADAYLTAFN
LRPGENTLYWIENGVFQTSVQKIVPYLNSFLAED

Specific function: Required for Pcad induction, a promoter upstream of cadB that is responsible for the pH-regulated expression of cadA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790576, Length=522, Percent_Identity=58.0459770114943, Blast_Score=590, Evalue=1e-170,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011990
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 58251; Mature: 58251

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQPVVRIGEWLVTPSVNQISRQGRQITLEPRLIDLLMYFAHHPDEVLSRDNIIDHVWMR
CCCCHHHHCCEEECCCHHHHHHCCCEEEECHHHHHHHHHHHCCCHHHHHHCCHHHHHHHH
TIVTNHVVTQSISELRKSLRDGGDSNAEYIVTVPKRGYKLTAPVIWCEENSDEIDNLSTS
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCEEEECCCCCCCCCCCCC
PPPPIAATNAEPTEGVPAAAPVPPASLQTPTKKAKKPRIAAFWTWVMFLLSLATLVVFIV
CCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
MSVVDHNAAVTKTRLLLNPRDIDVRFEGGNSCNNWVSQESYAIGLGGLITDLLNTYSTFM
HHHHCCCCHHEEEEEEECCCCEEEEECCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHEEE
VHDKTNYRVNEPSNSGKTLTIQFVNQRHYRAQQCFMSVVLIDNADGSTMLDKRYFVTNTN
EECCCCEEECCCCCCCCEEEEEEECCHHHHHHHHHEEEEEEECCCCCCEECCEEEEECCC
QLSIQDDLFNSLSFVLTQPWPNRMREQLALFRTPQNTALMRFYEARQLILSGDAQALSKA
EEEEHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
GDILNGIIKETPDFNYAYEYKVLVDVLRQSQQPFDKEQVAALNEEFKKIDQIPGVEKTSV
HHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEE
YYKIKTVDLLGKGDIDAAYEEINKSIELEMSWFNYVLLGKVYEMKGENRLAADAYLTAFN
EEEEEEEEEECCCCHHHHHHHCCCCEEEEEHHHHEEHHHHHHHHCCCCCEEHHHEEEEEE
LRPGENTLYWIENGVFQTSVQKIVPYLNSFLAED
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQQPVVRIGEWLVTPSVNQISRQGRQITLEPRLIDLLMYFAHHPDEVLSRDNIIDHVWMR
CCCCHHHHCCEEECCCHHHHHHCCCEEEECHHHHHHHHHHHCCCHHHHHHCCHHHHHHHH
TIVTNHVVTQSISELRKSLRDGGDSNAEYIVTVPKRGYKLTAPVIWCEENSDEIDNLSTS
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCEEEECCCCCCCCCCCCC
PPPPIAATNAEPTEGVPAAAPVPPASLQTPTKKAKKPRIAAFWTWVMFLLSLATLVVFIV
CCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
MSVVDHNAAVTKTRLLLNPRDIDVRFEGGNSCNNWVSQESYAIGLGGLITDLLNTYSTFM
HHHHCCCCHHEEEEEEECCCCEEEEECCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHEEE
VHDKTNYRVNEPSNSGKTLTIQFVNQRHYRAQQCFMSVVLIDNADGSTMLDKRYFVTNTN
EECCCCEEECCCCCCCCEEEEEEECCHHHHHHHHHEEEEEEECCCCCCEECCEEEEECCC
QLSIQDDLFNSLSFVLTQPWPNRMREQLALFRTPQNTALMRFYEARQLILSGDAQALSKA
EEEEHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
GDILNGIIKETPDFNYAYEYKVLVDVLRQSQQPFDKEQVAALNEEFKKIDQIPGVEKTSV
HHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEE
YYKIKTVDLLGKGDIDAAYEEINKSIELEMSWFNYVLLGKVYEMKGENRLAADAYLTAFN
EEEEEEEEEECCCCHHHHHHHCCCCEEEEEHHHHEEHHHHHHHHCCCCCEEHHHEEEEEE
LRPGENTLYWIENGVFQTSVQKIVPYLNSFLAED
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370290; 7610040; 9278503 [H]