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The map label for this gene is pssA [H]

Identifier: 29140793

GI number: 29140793

Start: 295239

End: 296594

Strand: Reverse

Name: pssA [H]

Synonym: t0258

Alternate gene names: 29140793

Gene position: 296594-295239 (Counterclockwise)

Preceding gene: 29140794

Following gene: 29140792

Centisome position: 6.19

GC content: 49.71

Gene sequence:

>1356_bases
ATGTTGTCAAAATTTAAGCGTAATAAACATCAACAACACCTTGCCCAACTCCCTAAGATTTCTCAGTCAGTTGATGATGT
AGATTTCTTTTATACTCCTGCTACTTTTCGGGAGACACTGCTGGAGAAAATCGCCAGCGCGACGCAGCGTATTTGTATCG
TTGCCCTGTATCTGGAACAGGACGATGGGGGTAAAGGTATACTCGACGCGCTCTATGCGGCTAAACGGCAGCGTCCTGAA
CTGGACGTGAGGGTGCTGGTCGACTGGCATCGCGCGCAACGCGGGCGCATTGGCGCAGCGGCCTCGAATACCAATGCAGA
CTGGTATTGCCGACTGGCGCAGGAAAACCCCGGCATTGATGTCCCGGTTTACGGCGTGCCGATTAATACGCGAGAAGCGC
TTGGCGTACTGCATTTTAAAGGCTTTATCATTGATGATAGCGTCCTGTACAGCGGCGCCAGCCTGAACGATGTCTATCTC
CATCAGCATGACAAATATCGCTACGATCGCTACCAGCTGATTCGCAATCGGCAAATGGCAGACATCATGTTTGACTGGGT
GACGCAAAATCTGATGAATGGCCGTGGTGTGAATCGTCTGGATAATACCCAGCGGCCGAAAAGCCCGGAGATTAAAAACG
ATATCCGCTTATACCGTCAGGAGCTGCGTGATGCGTCATATCATTTTCAGGGTGACGCTAATGACGAGCAGCTCTCCGTT
ACGCCGCTGGTCGGGCTTGGAAAATCCAGTCTGCTGAACAAAACCATTTTCCATCTCATGCCCTGTGCGGAGCATAAGCT
CACCATTTGTACCCCTTACTTCAATCTACCAGCGGTACTGGTGCGGAATATTATTCAGCTACTGCGCGACGGAAAGAAAG
TCGAAATCATTGTTGGCGATAAAACCGCGAATGATTTTTACATTCCGGAAGATGAACCGTTCAAGATCATTGGCGCGCTG
CCCTATCTCTATGAGATTAACCTGCGCCGCTTCCTGAGCCGTTTACAGTATTACGTCAATACCGATCAGCTTGTGGTGCG
TCTGTGGAAAGATGACGACAATACCTATCATTTGAAAGGGATGTGGGTAGATGATAAATGGATGCTACTCACCGGCAACA
ATCTGAATCCTCGCGCCTGGCGTCTGGATCTGGAAAACGCCATTCTGATCCACGATCCTAAGCAAGAGCTTGCCCCTCAG
CGGGAAAAAGAGCTGGAACTTATCCGAACGCACACAACCATCGTAAAACATTATCGTGACCTGCAGAGCATTGCCGACTA
TCCGATAAAAGTGCGTAAATTGATTCGCCGTCTGCGCCGGATCCGCATCGACAGATTAATTAGCCGTATCCTGTAA

Upstream 100 bases:

>100_bases
ATGTTGACCACTTTAACGGGTACTGATGTTATTATTGCTCGCTTATGTCGTCTGCATAGCACAGAGGACCCTTCAATGAA
CAGAGAAGAAATGCACTGTG

Downstream 100 bases:

>100_bases
TCGAAGCCCCGTCCTGTACGGGGTTTTCTCTTAGGAGTGAACTGGTGCGCGTGTTGATTCCTTTTACGGTGTTGTTTCTC
TCCGGGTGCAGCCATCTGGC

Product: phosphatidylserine synthase

Products: NA

Alternate protein names: Phosphatidylserine synthase [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYTPATFRETLLEKIASATQRICIVALYLEQDDGGKGILDALYAAKRQRPE
LDVRVLVDWHRAQRGRIGAAASNTNADWYCRLAQENPGIDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
HQHDKYRYDRYQLIRNRQMADIMFDWVTQNLMNGRGVNRLDNTQRPKSPEIKNDIRLYRQELRDASYHFQGDANDEQLSV
TPLVGLGKSSLLNKTIFHLMPCAEHKLTICTPYFNLPAVLVRNIIQLLRDGKKVEIIVGDKTANDFYIPEDEPFKIIGAL
PYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLLTGNNLNPRAWRLDLENAILIHDPKQELAPQ
REKELELIRTHTTIVKHYRDLQSIADYPIKVRKLIRRLRRIRIDRLISRIL

Sequences:

>Translated_451_residues
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYTPATFRETLLEKIASATQRICIVALYLEQDDGGKGILDALYAAKRQRPE
LDVRVLVDWHRAQRGRIGAAASNTNADWYCRLAQENPGIDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
HQHDKYRYDRYQLIRNRQMADIMFDWVTQNLMNGRGVNRLDNTQRPKSPEIKNDIRLYRQELRDASYHFQGDANDEQLSV
TPLVGLGKSSLLNKTIFHLMPCAEHKLTICTPYFNLPAVLVRNIIQLLRDGKKVEIIVGDKTANDFYIPEDEPFKIIGAL
PYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLLTGNNLNPRAWRLDLENAILIHDPKQELAPQ
REKELELIRTHTTIVKHYRDLQSIADYPIKVRKLIRRLRRIRIDRLISRIL
>Mature_451_residues
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYTPATFRETLLEKIASATQRICIVALYLEQDDGGKGILDALYAAKRQRPE
LDVRVLVDWHRAQRGRIGAAASNTNADWYCRLAQENPGIDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
HQHDKYRYDRYQLIRNRQMADIMFDWVTQNLMNGRGVNRLDNTQRPKSPEIKNDIRLYRQELRDASYHFQGDANDEQLSV
TPLVGLGKSSLLNKTIFHLMPCAEHKLTICTPYFNLPAVLVRNIIQLLRDGKKVEIIVGDKTANDFYIPEDEPFKIIGAL
PYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLLTGNNLNPRAWRLDLENAILIHDPKQELAPQ
REKELELIRTHTTIVKHYRDLQSIADYPIKVRKLIRRLRRIRIDRLISRIL

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI87082134, Length=431, Percent_Identity=93.5034802784223, Blast_Score=848, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25143331, Length=458, Percent_Identity=24.4541484716157, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319842, Length=284, Percent_Identity=25, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016270
- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: =2.7.8.8 [H]

Molecular weight: Translated: 52734; Mature: 52734

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYTPATFRETLLEKIASATQRICIVALYLEQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHCEEEEEEEEEC
DDGGKGILDALYAAKRQRPELDVRVLVDWHRAQRGRIGAAASNTNADWYCRLAQENPGID
CCCCCHHHHHHHHHHHCCCCCCEEEEEEEHHHCCCCCCCCCCCCCCCEEEEEECCCCCCC
VPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYLHQHDKYRYDRYQLIRNRQMA
CEEEECCCCCHHHHEEEEEEEEEEECHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCHHH
DIMFDWVTQNLMNGRGVNRLDNTQRPKSPEIKNDIRLYRQELRDASYHFQGDANDEQLSV
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCEEEE
TPLVGLGKSSLLNKTIFHLMPCAEHKLTICTPYFNLPAVLVRNIIQLLRDGKKVEIIVGD
EEEECCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECC
KTANDFYIPEDEPFKIIGALPYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKG
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEE
MWVDDKWMLLTGNNLNPRAWRLDLENAILIHDPKQELAPQREKELELIRTHTTIVKHYRD
EEECCEEEEEECCCCCCCEEEEECCCEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHH
LQSIADYPIKVRKLIRRLRRIRIDRLISRIL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYTPATFRETLLEKIASATQRICIVALYLEQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHCEEEEEEEEEC
DDGGKGILDALYAAKRQRPELDVRVLVDWHRAQRGRIGAAASNTNADWYCRLAQENPGID
CCCCCHHHHHHHHHHHCCCCCCEEEEEEEHHHCCCCCCCCCCCCCCCEEEEEECCCCCCC
VPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYLHQHDKYRYDRYQLIRNRQMA
CEEEECCCCCHHHHEEEEEEEEEEECHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCHHH
DIMFDWVTQNLMNGRGVNRLDNTQRPKSPEIKNDIRLYRQELRDASYHFQGDANDEQLSV
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCEEEE
TPLVGLGKSSLLNKTIFHLMPCAEHKLTICTPYFNLPAVLVRNIIQLLRDGKKVEIIVGD
EEEECCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECC
KTANDFYIPEDEPFKIIGALPYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKG
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEE
MWVDDKWMLLTGNNLNPRAWRLDLENAILIHDPKQELAPQREKELELIRTHTTIVKHYRD
EEECCEEEEEECCCCCCCEEEEECCCEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHH
LQSIADYPIKVRKLIRRLRRIRIDRLISRIL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2002065; 9205837; 9278503; 1323044 [H]