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The map label for this gene is kdgT

Identifier: 29140707

GI number: 29140707

Start: 192379

End: 193332

Strand: Direct

Name: kdgT

Synonym: t0166

Alternate gene names: 29140707

Gene position: 192379-193332 (Clockwise)

Preceding gene: 29140706

Following gene: 29140708

Centisome position: 4.01

GC content: 57.65

Gene sequence:

>954_bases
ATGAACATCAAAAAAGCAATAGAGCGCGTACCCGGCGGCATGATGGTCGTACCGCTCGTTATTGGCGCAGTCATTAACAC
CTTCGCCCCGCAGGCGCTTGAGATTGGCGGTTTTACCACTGCCTTATTTAAAAACGGCGCGGCGCCGCTGATTGGCGCTT
TTCTGCTGTGTATGGGAGCCGGTATCAGTGTGAAAGCCGCGCCCCAGGCGTTATTGCAGGGCGGGACGATTACGCTCACT
AAGTTGCTTGTCGCCATCGGCATTGGCCTGGGCGTGGAGCATCTTTTCGGCGCGGAGGGTATTTTTGGCCTGAGCGGCGT
GGCGATTATCGCGGCGATGAGCAATTCGAATGGCGGACTTTATGCTGCGTTGGTAGGCGAATTCGGCAATGAGCGCGACG
TCGGCGCTATCTCTATTTTGTCTCTTAATGATGGCCCTTTCTTTACGATGATTGCGCTGGGCGCGGCAGGGATGGCGAAC
ATTCCCATTATGGCGCTGGTGGCGGTGCTGGTTCCGCTGGTTGTCGGCATGATCCTCGGCAATCTTGATCCTCATATGCG
CGATTTTTTGACCAAAGGCGGCCCGCTGCTCATTCCTTTCTTTGCTTTTGCGCTGGGGGCGGGCATCAACCTGGAAATGT
TACTGCAAGGCGGACTTGCCGGAATTCTGCTCGGCGTGCTGACAACGTTCGTTGGCGGTTTCTTTAATATTCGCGCAGAT
CGTCTGGTTGGCGGAACTGGCATTGCCGGGGCGGCGGCCTCCAGCACTGCGGGTAATGCCGTTGCGACGCCGCTGGCTAT
TGCGCAGGCCGACCCTTCGCTCGCCGAGGTGGCCGCTGCTGCCGCTCCGCTGATTGCCGCCTCGGTGATCACCACGGCAA
TCCTGACGCCAGTGTTGACCTCCTGGGTTGCGAAAAAACAGGCGCGTCAGGCTTCTTTGGAGAAAAACGCATGA

Upstream 100 bases:

>100_bases
TCATTTTAAAACTGTGATCTGACGCGTTTGTGATCTTAATTTGATTGAATATAATCGTTATGATTTTATTCAATCACAAC
AAGCAACAGGCGGTAAGACC

Downstream 100 bases:

>100_bases
AAATGATGGTTATCGCCGATGATTTTACCGGATCGAATGATACCGGCGTCCAGTTGGCGAAGAAGGGGGCGAGAACGGAA
GTCATGTTGAGCGCGTCGCA

Product: 2-keto-3-deoxygluconate permease

Products: Proton [Cytoplasm]; 2-dehydro-3-deoxy-D-gluconate [Cytoplasm] [C]

Alternate protein names: KDG permease 1

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNIKKAIERVPGGMMVVPLVIGAVINTFAPQALEIGGFTTALFKNGAAPLIGAFLLCMGAGISVKAAPQALLQGGTITLT
KLLVAIGIGLGVEHLFGAEGIFGLSGVAIIAAMSNSNGGLYAALVGEFGNERDVGAISILSLNDGPFFTMIALGAAGMAN
IPIMALVAVLVPLVVGMILGNLDPHMRDFLTKGGPLLIPFFAFALGAGINLEMLLQGGLAGILLGVLTTFVGGFFNIRAD
RLVGGTGIAGAAASSTAGNAVATPLAIAQADPSLAEVAAAAAPLIAASVITTAILTPVLTSWVAKKQARQASLEKNA

Sequences:

>Translated_317_residues
MNIKKAIERVPGGMMVVPLVIGAVINTFAPQALEIGGFTTALFKNGAAPLIGAFLLCMGAGISVKAAPQALLQGGTITLT
KLLVAIGIGLGVEHLFGAEGIFGLSGVAIIAAMSNSNGGLYAALVGEFGNERDVGAISILSLNDGPFFTMIALGAAGMAN
IPIMALVAVLVPLVVGMILGNLDPHMRDFLTKGGPLLIPFFAFALGAGINLEMLLQGGLAGILLGVLTTFVGGFFNIRAD
RLVGGTGIAGAAASSTAGNAVATPLAIAQADPSLAEVAAAAAPLIAASVITTAILTPVLTSWVAKKQARQASLEKNA
>Mature_317_residues
MNIKKAIERVPGGMMVVPLVIGAVINTFAPQALEIGGFTTALFKNGAAPLIGAFLLCMGAGISVKAAPQALLQGGTITLT
KLLVAIGIGLGVEHLFGAEGIFGLSGVAIIAAMSNSNGGLYAALVGEFGNERDVGAISILSLNDGPFFTMIALGAAGMAN
IPIMALVAVLVPLVVGMILGNLDPHMRDFLTKGGPLLIPFFAFALGAGINLEMLLQGGLAGILLGVLTTFVGGFFNIRAD
RLVGGTGIAGAAASSTAGNAVATPLAIAQADPSLAEVAAAAAPLIAASVITTAILTPVLTSWVAKKQARQASLEKNA

Specific function: The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdgT transporter family

Homologues:

Organism=Escherichia coli, GI87082349, Length=322, Percent_Identity=45.0310559006211, Blast_Score=224, Evalue=7e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDGT1_SALTI (P65208)

Other databases:

- EMBL:   AL627265
- EMBL:   AE014613
- RefSeq:   NP_454774.1
- RefSeq:   NP_804049.1
- GeneID:   1067751
- GeneID:   1246677
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t0166
- KEGG:   sty:STY0183
- HOGENOM:   HBG322377
- OMA:   MIEYNRY
- ProtClustDB:   PRK12460
- BioCyc:   SENT209261:T0166-MONOMER
- BioCyc:   SENT220341:STY0183-MONOMER
- HAMAP:   MF_00070
- InterPro:   IPR004684
- ProDom:   PD024513

Pfam domain/function: PF03812 KdgT

EC number: NA

Molecular weight: Translated: 31679; Mature: 31679

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0xc382950)-; HASH(0xc23e4fc)-; HASH(0xbde6388)-; HASH(0xc3e0334)-; HASH(0xc409788)-; HASH(0xb9dfab4)-; HASH(0xb136d40)-; HASH(0x41f8da88)-; HASH(0x41fa6a54)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKKAIERVPGGMMVVPLVIGAVINTFAPQALEIGGFTTALFKNGAAPLIGAFLLCMGA
CCHHHHHHHCCCCEEHHHHHHHHHHHHCCCCHHHHCCHHHHHHHCCCHHHHHHHHHHHCC
GISVKAAPQALLQGGTITLTKLLVAIGIGLGVEHLFGAEGIFGLSGVAIIAAMSNSNGGL
CCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCEEHEEEEECCCCCE
YAALVGEFGNERDVGAISILSLNDGPFFTMIALGAAGMANIPIMALVAVLVPLVVGMILG
EEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHC
NLDPHMRDFLTKGGPLLIPFFAFALGAGINLEMLLQGGLAGILLGVLTTFVGGFFNIRAD
CCCHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHCHHHHEEHH
RLVGGTGIAGAAASSTAGNAVATPLAIAQADPSLAEVAAAAAPLIAASVITTAILTPVLT
HEECCCCCCCCCCCCCCCCHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SWVAKKQARQASLEKNA
HHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MNIKKAIERVPGGMMVVPLVIGAVINTFAPQALEIGGFTTALFKNGAAPLIGAFLLCMGA
CCHHHHHHHCCCCEEHHHHHHHHHHHHCCCCHHHHCCHHHHHHHCCCHHHHHHHHHHHCC
GISVKAAPQALLQGGTITLTKLLVAIGIGLGVEHLFGAEGIFGLSGVAIIAAMSNSNGGL
CCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCEEHEEEEECCCCCE
YAALVGEFGNERDVGAISILSLNDGPFFTMIALGAAGMANIPIMALVAVLVPLVVGMILG
EEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHC
NLDPHMRDFLTKGGPLLIPFFAFALGAGINLEMLLQGGLAGILLGVLTTFVGGFFNIRAD
CCCHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHCHHHHEEHH
RLVGGTGIAGAAASSTAGNAVATPLAIAQADPSLAEVAAAAAPLIAASVITTAILTPVLT
HEECCCCCCCCCCCCCCCCHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SWVAKKQARQASLEKNA
HHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 2-dehydro-3-deoxy-D-gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 2-dehydro-3-deoxy-D-gluconate [Periplasm] = Proton [Cytoplasm] + 2-dehydro-3-deoxy-D-gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504