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The map label for this gene is coaE [H]

Identifier: 29140687

GI number: 29140687

Start: 166345

End: 166965

Strand: Reverse

Name: coaE [H]

Synonym: t0146

Alternate gene names: 29140687

Gene position: 166965-166345 (Counterclockwise)

Preceding gene: 29140689

Following gene: 29140686

Centisome position: 3.48

GC content: 54.27

Gene sequence:

>621_bases
ATGAGGTATACCGTAGCCTTAACCGGCGGTATTGGCAGCGGTAAAAGTACCGTCGCTGATGCCTTCGCTGACCTCGGAAT
AACCGTCATCGACGCGGATATTATCGCGCGCCAGATGGTTGAGCCAGGGCAGCCCGCCCTGAACGCAATAGCGGAACATT
TTGGTTCTGAACTTATCGCCGCCGACGGCACGTTACGTCGCCGGGCACTGCGTGAGCGTATTTTTTCGCATCCGGAAGAA
AAAGCCTGGCTTAACGCTCTGCTTCATCCCTTAATTCAGCAGGAAACCCAACGACAGTTTCAACAGGCTACGTCGCCCTA
TGTGTTATGGGTTGTGCCTCTGCTGGTTGAAAACAGGTTGTATCAAAAAGCCAACCGCGTACTGGTGGTTGACGTTACGC
CCGAAACGCAGCTCATACGCACAATGCAGCGTGATGATGTTACGCGCGAGCATGTTGAACACATTCTCGCTGCGCAGGCG
ACGCGTGAAGCGCGCCTTGCCGTGGCGGACGATGTTATTGATAATAACGGCGCACCGGATGCTATCGCATCAGATGTGGC
CCGCCTGCACGCCAGTTATCTTAAGCTCGCGTCGCAGTTTGTCTCACAGGAAAAACCGTAA

Upstream 100 bases:

>100_bases
TTACCTGGCGAATAGTAGGTTAATGCTCAGAGCATATCGTCTTTGTATGTTTAAAATTTAACCTTTTGATTATCAAACTA
AAATTCCGGAAGCTGGAGAT

Downstream 100 bases:

>100_bases
TGCACACCCAGGTCCTATTTGAACACCCTCTCAATGAGAAGATGCGTACGTGGCTGCGCATAGAGTTTTTGATCCAACAG
CTCTCCATCAACCTGCCAAT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MRYTVALTGGIGSGKSTVADAFADLGITVIDADIIARQMVEPGQPALNAIAEHFGSELIAADGTLRRRALRERIFSHPEE
KAWLNALLHPLIQQETQRQFQQATSPYVLWVVPLLVENRLYQKANRVLVVDVTPETQLIRTMQRDDVTREHVEHILAAQA
TREARLAVADDVIDNNGAPDAIASDVARLHASYLKLASQFVSQEKP

Sequences:

>Translated_206_residues
MRYTVALTGGIGSGKSTVADAFADLGITVIDADIIARQMVEPGQPALNAIAEHFGSELIAADGTLRRRALRERIFSHPEE
KAWLNALLHPLIQQETQRQFQQATSPYVLWVVPLLVENRLYQKANRVLVVDVTPETQLIRTMQRDDVTREHVEHILAAQA
TREARLAVADDVIDNNGAPDAIASDVARLHASYLKLASQFVSQEKP
>Mature_206_residues
MRYTVALTGGIGSGKSTVADAFADLGITVIDADIIARQMVEPGQPALNAIAEHFGSELIAADGTLRRRALRERIFSHPEE
KAWLNALLHPLIQQETQRQFQQATSPYVLWVVPLLVENRLYQKANRVLVVDVTPETQLIRTMQRDDVTREHVEHILAAQA
TREARLAVADDVIDNNGAPDAIASDVARLHASYLKLASQFVSQEKP

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=193, Percent_Identity=36.2694300518135, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI191252795, Length=193, Percent_Identity=36.2694300518135, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI110227607, Length=164, Percent_Identity=28.6585365853659, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI110227605, Length=164, Percent_Identity=28.6585365853659, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI110227603, Length=164, Percent_Identity=28.6585365853659, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI110227601, Length=164, Percent_Identity=28.6585365853659, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI205277394, Length=164, Percent_Identity=28.6585365853659, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1786292, Length=206, Percent_Identity=88.8349514563107, Blast_Score=354, Evalue=3e-99,
Organism=Caenorhabditis elegans, GI17554944, Length=192, Percent_Identity=35.9375, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6320402, Length=208, Percent_Identity=35.0961538461538, Blast_Score=102, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24644728, Length=192, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24658602, Length=162, Percent_Identity=30.2469135802469, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22795; Mature: 22795

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYTVALTGGIGSGKSTVADAFADLGITVIDADIIARQMVEPGQPALNAIAEHFGSELIA
CEEEEEEECCCCCCHHHHHHHHHHCCHHEEHHHHHHHHHCCCCCHHHHHHHHHHCCHHHH
ADGTLRRRALRERIFSHPEEKAWLNALLHPLIQQETQRQFQQATSPYVLWVVPLLVENRL
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
YQKANRVLVVDVTPETQLIRTMQRDDVTREHVEHILAAQATREARLAVADDVIDNNGAPD
HHHHCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
AIASDVARLHASYLKLASQFVSQEKP
HHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRYTVALTGGIGSGKSTVADAFADLGITVIDADIIARQMVEPGQPALNAIAEHFGSELIA
CEEEEEEECCCCCCHHHHHHHHHHCCHHEEHHHHHHHHHCCCCCHHHHHHHHHHCCHHHH
ADGTLRRRALRERIFSHPEEKAWLNALLHPLIQQETQRQFQQATSPYVLWVVPLLVENRL
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
YQKANRVLVVDVTPETQLIRTMQRDDVTREHVEHILAAQATREARLAVADDVIDNNGAPD
HHHHCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
AIASDVARLHASYLKLASQFVSQEKP
HHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA