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The map label for this gene is est [H]

Identifier: 28377649

GI number: 28377649

Start: 732496

End: 733245

Strand: Direct

Name: est [H]

Synonym: lp_0796

Alternate gene names: 28377649

Gene position: 732496-733245 (Clockwise)

Preceding gene: 28377648

Following gene: 28377650

Centisome position: 22.14

GC content: 45.33

Gene sequence:

>750_bases
ATGATGCTGAAACAACCGGAACCGTTTTTCTTTGAACATGGCCAACATGCCGTCATTTTATTGCACGCCTATGCGGGAAG
TGCCAATGATGTGCGGATGTTAGCACGAGCATTAGAACGGGAAGATTATACAGTTTATGGCCCCCAATTCAGTGGACACG
CGACTGATGATCCACGAGATATTCTCGCACAGACGCCGGCGCAATGGTGGCAAGATACGCAACAAGCAATATCATTTATG
CGGCAAAAAGGCTATACTAAAATTAGTATCTTTGGCTTATCATTAGGTGGTATTTTTGCGACGGCGGCCTTGGAGCGTGA
TCCTCAGTTGCTAGGTGGTGGCACGTTTAGTTCACCACTATTTGCTGGTAATCGTAGTGACGTTGCTGAAATGTTTATCA
CGCTGAGTCACCATCAACTGGCGCACAGTCAATTTTCAATTGCCGAGCGTGAACAGATCTTAATGACGTTGCCGGAACTG
GTTCAGCGGCAATTGCAGGCAGTCAATACCTTTACTACGACAGAGGTTACGAGTCACCTCAGCGCTGTGACCCAACCTTT
CTTCATTGGTCAGGGTGGGCAAGATGAATTAATTGATGCGACGGTGGCGCGACAATTACGTGATCAATTACCACAAGTAC
CAGTTGATTTTCATTGGTATGCTGATGCTGGACACGTGATTACCGTCAACAGTGCGCATCACCAATTGGAACAAGATGTT
TTAACATATTTAAAAACTATTTATAAATGA

Upstream 100 bases:

>100_bases
AATCGCATTCTTTATCCTGGCGTTAGCTCTAGCATGGTACTCATCGAAGTAATTGACCGTCCTCCTGTGATTTCAGGAGG
CTTTTTTTTAAGGTGGTGTA

Downstream 100 bases:

>100_bases
GGTAAATAATGTCAGAAGCAAACTTACAAGAACAAATCCTGACTTTTTTGCAAGCTCATCCCGATCGCACGTATAGTGTT
GAACAACTAACGGATGAATT

Product: carboxylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MMLKQPEPFFFEHGQHAVILLHAYAGSANDVRMLARALEREDYTVYGPQFSGHATDDPRDILAQTPAQWWQDTQQAISFM
RQKGYTKISIFGLSLGGIFATAALERDPQLLGGGTFSSPLFAGNRSDVAEMFITLSHHQLAHSQFSIAEREQILMTLPEL
VQRQLQAVNTFTTTEVTSHLSAVTQPFFIGQGGQDELIDATVARQLRDQLPQVPVDFHWYADAGHVITVNSAHHQLEQDV
LTYLKTIYK

Sequences:

>Translated_249_residues
MMLKQPEPFFFEHGQHAVILLHAYAGSANDVRMLARALEREDYTVYGPQFSGHATDDPRDILAQTPAQWWQDTQQAISFM
RQKGYTKISIFGLSLGGIFATAALERDPQLLGGGTFSSPLFAGNRSDVAEMFITLSHHQLAHSQFSIAEREQILMTLPEL
VQRQLQAVNTFTTTEVTSHLSAVTQPFFIGQGGQDELIDATVARQLRDQLPQVPVDFHWYADAGHVITVNSAHHQLEQDV
LTYLKTIYK
>Mature_249_residues
MMLKQPEPFFFEHGQHAVILLHAYAGSANDVRMLARALEREDYTVYGPQFSGHATDDPRDILAQTPAQWWQDTQQAISFM
RQKGYTKISIFGLSLGGIFATAALERDPQLLGGGTFSSPLFAGNRSDVAEMFITLSHHQLAHSQFSIAEREQILMTLPEL
VQRQLQAVNTFTTTEVTSHLSAVTQPFFIGQGGQDELIDATVARQLRDQLPQVPVDFHWYADAGHVITVNSAHHQLEQDV
LTYLKTIYK

Specific function: Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones [H]

COG id: COG1647

COG function: function code R; Esterase/lipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012354
- InterPro:   IPR001375 [H]

Pfam domain/function: PF00326 Peptidase_S9 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 27926; Mature: 27926

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLKQPEPFFFEHGQHAVILLHAYAGSANDVRMLARALEREDYTVYGPQFSGHATDDPRD
CCCCCCCCHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHH
ILAQTPAQWWQDTQQAISFMRQKGYTKISIFGLSLGGIFATAALERDPQLLGGGTFSSPL
HHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCC
FAGNRSDVAEMFITLSHHQLAHSQFSIAEREQILMTLPELVQRQLQAVNTFTTTEVTSHL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAVTQPFFIGQGGQDELIDATVARQLRDQLPQVPVDFHWYADAGHVITVNSAHHQLEQDV
HHHHCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEECCHHHHHHHHH
LTYLKTIYK
HHHHHHHCC
>Mature Secondary Structure
MMLKQPEPFFFEHGQHAVILLHAYAGSANDVRMLARALEREDYTVYGPQFSGHATDDPRD
CCCCCCCCHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHH
ILAQTPAQWWQDTQQAISFMRQKGYTKISIFGLSLGGIFATAALERDPQLLGGGTFSSPL
HHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCC
FAGNRSDVAEMFITLSHHQLAHSQFSIAEREQILMTLPELVQRQLQAVNTFTTTEVTSHL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAVTQPFFIGQGGQDELIDATVARQLRDQLPQVPVDFHWYADAGHVITVNSAHHQLEQDV
HHHHCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEECCHHHHHHHHH
LTYLKTIYK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1369099 [H]