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The map label for this gene is surA [H]

Identifier: 28199704

GI number: 28199704

Start: 2147700

End: 2149091

Strand: Reverse

Name: surA [H]

Synonym: PD1835

Alternate gene names: 28199704

Gene position: 2149091-2147700 (Counterclockwise)

Preceding gene: 28199705

Following gene: 28199703

Centisome position: 85.29

GC content: 53.16

Gene sequence:

>1392_bases
ATGACCAGATATTTTTCTATTGTTCTCTCTTTGCTGTTGGCTGTGTCCTGCGTGTTTTTGCCGGTGGCGTCAGCACGACA
GCAACAACATCAACCGCTTGATCGCATTGTTGCTGTGGTTGATGACAATGTGGTCTTGAAAAGCGAGCTTGATCGCGCGA
TTCACAATGTCAAATCACAGTATGTTGGCCATGAAGGCCAGTTACCGCCGGATGAAGTGTTGCAGCGCCAAGTGTTAGAA
CGCTTGATTTTGATCAAGCTGCAAGTTGCGCGGGCGCAGACCAATGGCATCCGCGTCAGTGACGATGAGCTGAATCAGGC
CATTTCCAGCATTGCTGAGAATAATAAGACCAGTGTTGATGGTCTTCGCCAAAAATTAGTTGCCGAAGGGATTTCTTTCC
CCGAATTCCGCCAGTCAGTGCGTGATGAGATTACCGTGCATCATTTGCGCCAAGGCTTTGCGCAGAGCCGTATTGTGGTC
AGTGAAGGTGAAGTGGATACCGCACTCGCGCAGGCCAACAGCGGTGCCCAGTATCATCTACAGCACATCTTGGTTTCCTT
GCCTGACGGGGCAACCTCCGAACAGATTGCGATTGCCCAGAAAAAAATCAATGGCATTAAGAGTGTGATCGATAAAGGCG
AACTTGCCTTTTCCGCTGCCGCAGTACGTTATTCCGATAGTCCCAACGCGCTTGAAAGTGGTGATTTGGGCTGGCGTAGC
CTTGACGAGATTCCCGAAGCATTTGCGCAGATGGTTCAAACCATGAAGCCTGGCCAGATCGTTGGTCCGCTGCGTGGCAC
CAGCGGTTTTCAGCTGCTTAAGCTCGTAGAAGTTCGCGATAGTACTGCTGCGGCGGGTCCGCGGCAGATGGCGACCGAAT
ACCACGCCCGCCACATTCTGGTTCGTATTACTGATAAACAGAAAGAAGCGCAAGCCAAGGCCAAAATCGACACCCTGCGT
GCTCGTATCGCTGGTGGTGCGGATTTCCAGACCGTTGCTCGAGAATCCTCAGAGGACGCTAACAACAGTAACCAGGGTGG
GGATCTTGGTTGGTTCCCGTCCGATGCGTTTGGGGCTGACTTTGGCAACCATGTTAAAGCGCTTGCTGACGGCAACGTCT
CCGAACCTTTCCGTAGCGCTGCCGGATGGCATATCGTGCAGCGTCTGGGCACCCGCCAGACAGATGTCACCAGGGAGAAC
CAGCGTGCCCAGATTCGTGACACGATTGGCCAACGCAAGTTAGAAGAATCTTATGAGCGTTTTTTGCGGGAACTCCGTAG
TGAAGCGTATGTGAGTCTTCAGATTGAGGAGCCAGCTGACGATCACCATACTCCCAGTGCGGCGGTGACCCCGGCAACAG
GGGCCGTATTACCGGCCGCAACGAAGCACTGA

Upstream 100 bases:

>100_bases
TACGCCGTGCTATTCTCGGTTACTATCGCGATGACCTTTACTTGGTTCCGCCTAGTAATACGACGACCGATCCAGACGCT
TACGATCCAAATAAGATTCC

Downstream 100 bases:

>100_bases
TTTATGTTGCACCCCGCGCTTGCTTTGGTTCCTGGCGAACCGGCGGGCGTTGGCCCTGAATTGTGCGTGCGGTTGGTACA
ACAGCCGCGTCAAGATTGCC

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTRYFSIVLSLLLAVSCVFLPVASARQQQHQPLDRIVAVVDDNVVLKSELDRAIHNVKSQYVGHEGQLPPDEVLQRQVLE
RLILIKLQVARAQTNGIRVSDDELNQAISSIAENNKTSVDGLRQKLVAEGISFPEFRQSVRDEITVHHLRQGFAQSRIVV
SEGEVDTALAQANSGAQYHLQHILVSLPDGATSEQIAIAQKKINGIKSVIDKGELAFSAAAVRYSDSPNALESGDLGWRS
LDEIPEAFAQMVQTMKPGQIVGPLRGTSGFQLLKLVEVRDSTAAAGPRQMATEYHARHILVRITDKQKEAQAKAKIDTLR
ARIAGGADFQTVARESSEDANNSNQGGDLGWFPSDAFGADFGNHVKALADGNVSEPFRSAAGWHIVQRLGTRQTDVTREN
QRAQIRDTIGQRKLEESYERFLRELRSEAYVSLQIEEPADDHHTPSAAVTPATGAVLPAATKH

Sequences:

>Translated_463_residues
MTRYFSIVLSLLLAVSCVFLPVASARQQQHQPLDRIVAVVDDNVVLKSELDRAIHNVKSQYVGHEGQLPPDEVLQRQVLE
RLILIKLQVARAQTNGIRVSDDELNQAISSIAENNKTSVDGLRQKLVAEGISFPEFRQSVRDEITVHHLRQGFAQSRIVV
SEGEVDTALAQANSGAQYHLQHILVSLPDGATSEQIAIAQKKINGIKSVIDKGELAFSAAAVRYSDSPNALESGDLGWRS
LDEIPEAFAQMVQTMKPGQIVGPLRGTSGFQLLKLVEVRDSTAAAGPRQMATEYHARHILVRITDKQKEAQAKAKIDTLR
ARIAGGADFQTVARESSEDANNSNQGGDLGWFPSDAFGADFGNHVKALADGNVSEPFRSAAGWHIVQRLGTRQTDVTREN
QRAQIRDTIGQRKLEESYERFLRELRSEAYVSLQIEEPADDHHTPSAAVTPATGAVLPAATKH
>Mature_462_residues
TRYFSIVLSLLLAVSCVFLPVASARQQQHQPLDRIVAVVDDNVVLKSELDRAIHNVKSQYVGHEGQLPPDEVLQRQVLER
LILIKLQVARAQTNGIRVSDDELNQAISSIAENNKTSVDGLRQKLVAEGISFPEFRQSVRDEITVHHLRQGFAQSRIVVS
EGEVDTALAQANSGAQYHLQHILVSLPDGATSEQIAIAQKKINGIKSVIDKGELAFSAAAVRYSDSPNALESGDLGWRSL
DEIPEAFAQMVQTMKPGQIVGPLRGTSGFQLLKLVEVRDSTAAAGPRQMATEYHARHILVRITDKQKEAQAKAKIDTLRA
RIAGGADFQTVARESSEDANNSNQGGDLGWFPSDAFGADFGNHVKALADGNVSEPFRSAAGWHIVQRLGTRQTDVTRENQ
RAQIRDTIGQRKLEESYERFLRELRSEAYVSLQIEEPADDHHTPSAAVTPATGAVLPAATKH

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=431, Percent_Identity=32.2505800464037, Blast_Score=231, Evalue=6e-62,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 50731; Mature: 50599

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYFSIVLSLLLAVSCVFLPVASARQQQHQPLDRIVAVVDDNVVLKSELDRAIHNVKSQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YVGHEGQLPPDEVLQRQVLERLILIKLQVARAQTNGIRVSDDELNQAISSIAENNKTSVD
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHH
GLRQKLVAEGISFPEFRQSVRDEITVHHLRQGFAQSRIVVSEGEVDTALAQANSGAQYHL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHCCCCHHHHH
QHILVSLPDGATSEQIAIAQKKINGIKSVIDKGELAFSAAAVRYSDSPNALESGDLGWRS
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEECCCCCCCCCCCCCHHH
LDEIPEAFAQMVQTMKPGQIVGPLRGTSGFQLLKLVEVRDSTAAAGPRQMATEYHARHIL
HHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCEEE
VRITDKQKEAQAKAKIDTLRARIAGGADFQTVARESSEDANNSNQGGDLGWFPSDAFGAD
EEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
FGNHVKALADGNVSEPFRSAAGWHIVQRLGTRQTDVTRENQRAQIRDTIGQRKLEESYER
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FLRELRSEAYVSLQIEEPADDHHTPSAAVTPATGAVLPAATKH
HHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRYFSIVLSLLLAVSCVFLPVASARQQQHQPLDRIVAVVDDNVVLKSELDRAIHNVKSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YVGHEGQLPPDEVLQRQVLERLILIKLQVARAQTNGIRVSDDELNQAISSIAENNKTSVD
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHH
GLRQKLVAEGISFPEFRQSVRDEITVHHLRQGFAQSRIVVSEGEVDTALAQANSGAQYHL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHCCCCHHHHH
QHILVSLPDGATSEQIAIAQKKINGIKSVIDKGELAFSAAAVRYSDSPNALESGDLGWRS
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEECCCCCCCCCCCCCHHH
LDEIPEAFAQMVQTMKPGQIVGPLRGTSGFQLLKLVEVRDSTAAAGPRQMATEYHARHIL
HHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCEEE
VRITDKQKEAQAKAKIDTLRARIAGGADFQTVARESSEDANNSNQGGDLGWFPSDAFGAD
EEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
FGNHVKALADGNVSEPFRSAAGWHIVQRLGTRQTDVTRENQRAQIRDTIGQRKLEESYER
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FLRELRSEAYVSLQIEEPADDHHTPSAAVTPATGAVLPAATKH
HHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]