| Definition | Xylella fastidiosa Temecula1, complete genome. |
|---|---|
| Accession | NC_004556 |
| Length | 2,519,802 |
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The map label for this gene is pbpC [H]
Identifier: 28199167
GI number: 28199167
Start: 1494989
End: 1497379
Strand: Reverse
Name: pbpC [H]
Synonym: PD1281
Alternate gene names: 28199167
Gene position: 1497379-1494989 (Counterclockwise)
Preceding gene: 28199168
Following gene: 28199166
Centisome position: 59.42
GC content: 57.55
Gene sequence:
>2391_bases GTGAGTATGTTCGTGCTTCCATCATTGTCGGCCTCCATGTTTGGTCGTTTGCGCGATGATCGTGCATTGACTTGGCTGCG CTGGAGTTGTGCTGGACTGCTTTCGCTGCTTCTTCTGTTGGATGTGCTTTGCCCATTGCCATTACCGACCTCGCACGATA TGGCTTTGCTGGTGGTTGCTCGAGATGGTACTCCATTGCGTGCCTTCCCTGATGCTGATGGTGTATGGCGCTACCCGGCG CAGTTGGGACAGGTGTCGCCGTTGTATGTGCAGGCTCTGTTGACCTATGAGGACCGTATGTTCTGGCGCCATCCGGGGGT GAATCCTTGGGCGTTGTTACGTGCTGGGGGCCTGTGGCTGCGTTATGGTCATGTCGTTTCCGGTGGCTCGACGTTGACAA TGCAGGCGGCACGGATTCTTGAGCCGCATGGCCGTACTCCTTGGGGCAAACTCAAGCAGTTGTTGCGTGCAGTACAGTTA GAAGTCCATTTGAGTAAGCGCCAGATTTTGCAGTTGTATTTGGAACGTGCCCCTTACGGAGGGACGATCCAGGGCGTTGA GGCGGCAAGCTGGGCTTATCTTGGCAAGTCGGCGGCACGCTTATCGCATGCTGAGGCGGCGTTGCTGGCGGTATTGCCGC AGTCGCCAAGCCGGTTGCGTCCGGACCGTAATCCGCAGTTGGCACGGCAAGCACGCGATAAGGTGCTGGCACGCATGGCA GTGCTTGGTGTCTGGTCTGATGAAGAGGTGAAAGATGCGCGGCTGGAGCCGGTGGTTGCACGTGCATTGCAGCCACCCAT GTACGCGGCGTTGTTGGCGCAGCGTCTGCGTGTGCAACGGCCACATGCTGCACGCATTGTGACCACGTTGGACATTGATT TGCAGCGTACTCTTGAGGAAAGAGTGAGTACCTATTTCTCACCGTTACCTGAGCGCACTTCTGCTGCGGTGCTGGTGATG GATAATCAAAGCCTGGAAGCACGTGCCTACGTTGGTTCGGTGACATTCGGTGATGCCAAGCGGTTGGGTCACGTGGATAT GGTGCGGGCTTGGCGTTCGCCGGGTTCCACACTTAAACCGTTTCTTTATGGAATGGCGTTGGATCAGGGCTTGATTCATT CTGAGAGTTTGTTGGTCGATGCGCCACAGCATTTTGGTGATTATCGTCCGGGTAATTTCGATGCTGCGTTCACTGGCCCT ATTGGTGCGTCCAGTGCATTGCGACAGTCGTTGAACGTGCCTGCAGTCGATTTGTTGGAACGGATTGGGCCGGCTCGGTT TGCGACGCGTCTGGCGCATGCAGGGGTGCAGTTGCGTTTCCCACGCGGTGCCACCCCGAATTTGGCGTTGATCCTCGGGG GTGCAGGGGCACAGTTGCAGGAGCTGGTGGGTGCCTTCTCGGTGTTCAACCGCGGTGGCGTGGCAGGACGGGTGCGTTAT ACCCCGGAGGATCCGCGTATTGAGCGTCGTTTGATCTCCCCTGGTGCGGCTTGGATTGTGCGCGAGATTCTTGCTGCTAA CCCGCGCCCTGGGTATGGCAGGGGCACGTTCGATACTGCGATGCGTCCGTCCGTGGCTTGGAAGACTGGTACCAGCTATG GCTTCCGTGATGCTTGGGCGCTGGGGAGTACCCGCCGCTACACAGTGGGTGTTTGGGTTGGGCGTCCGGATGGTACCCCG CTGCCGGGTCAGTATGGTGCGATTACGGCATTACCGTTGTTGTTTGATGTGATTGATGTGTTACCACGCGCGCCTGGTGA TGCTGTGCCGGAGCCGATGCCAGCCAGTGTGGAGCAGGTTGATATCTGTTGGCCGCTGGGTTTTGCTGCTGCTAGCACGC CGCCGGAATTGTGCCGACGGCGCTACAGTGCCTACGTATTGGATGGGGTGGTGCCGCCGACCTTCGCTGAGCGTGATGCG AAATTGTGGCGTAGCGGTTTGGAACGATTCCAGGTCGATGTGCGTAGTGGTTTGCGTGTTAGGCCTGATTGTCGTCTGCC GCATCTGATCAGGGAGCAGCAGATTGCACGTTGGCCGACGTTGGTGATCCCATGGCTTGATGCTGTGGAGCGTCGTGCGA CGCATCTGCCTCGGCTGGCCTCAGACTGTTCTGAGGATGATCGTGCTGATGCTGGGGTGCTGTACATTGATGGTCTCGTT GAAGGTGCCACATTGCAGCGTCCACCTGGTAGTACCAAGCCGGTACATCTGCAGTTGCGTGCATTGGGCAGTGAAACACG GATCGACTGGCTCTTGGATGGGCGCTGGATTGCTCAAACTGTGGGGGGACAGACCTTTCAGCGTGATTTCCCAGAACCAG GGACGTATATCTTGACTGCGTTGGCTGAGGATGGTGCTTGGAACAGGATGCAGTTCCGCGTTTTACGTTAA
Upstream 100 bases:
>100_bases TGCAGAGTGACCGAAGCGCATGATCGCTCGTTAACTTCCCATAAGGCTTTGATTTTATGAGATCTTGGCGGAGCAGGCAC AATAGCCATCCCGTCCAGCA
Downstream 100 bases:
>100_bases GTAGGTGTGATGCAAAGTGTTTTCATTCCATCTCGGCAATGGGGGGAGGGAGTGCTCGTCTTTTGTTTCAATGTGTTGTT TCTTCCGCGCTTTGGTGAAT
Product: bifunctional penicillin-binding protein 1C precursor
Products: NA
Alternate protein names: PBP-1c; PBP1c; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Transpeptidase-like module [H]
Number of amino acids: Translated: 796; Mature: 795
Protein sequence:
>796_residues MSMFVLPSLSASMFGRLRDDRALTWLRWSCAGLLSLLLLLDVLCPLPLPTSHDMALLVVARDGTPLRAFPDADGVWRYPA QLGQVSPLYVQALLTYEDRMFWRHPGVNPWALLRAGGLWLRYGHVVSGGSTLTMQAARILEPHGRTPWGKLKQLLRAVQL EVHLSKRQILQLYLERAPYGGTIQGVEAASWAYLGKSAARLSHAEAALLAVLPQSPSRLRPDRNPQLARQARDKVLARMA VLGVWSDEEVKDARLEPVVARALQPPMYAALLAQRLRVQRPHAARIVTTLDIDLQRTLEERVSTYFSPLPERTSAAVLVM DNQSLEARAYVGSVTFGDAKRLGHVDMVRAWRSPGSTLKPFLYGMALDQGLIHSESLLVDAPQHFGDYRPGNFDAAFTGP IGASSALRQSLNVPAVDLLERIGPARFATRLAHAGVQLRFPRGATPNLALILGGAGAQLQELVGAFSVFNRGGVAGRVRY TPEDPRIERRLISPGAAWIVREILAANPRPGYGRGTFDTAMRPSVAWKTGTSYGFRDAWALGSTRRYTVGVWVGRPDGTP LPGQYGAITALPLLFDVIDVLPRAPGDAVPEPMPASVEQVDICWPLGFAAASTPPELCRRRYSAYVLDGVVPPTFAERDA KLWRSGLERFQVDVRSGLRVRPDCRLPHLIREQQIARWPTLVIPWLDAVERRATHLPRLASDCSEDDRADAGVLYIDGLV EGATLQRPPGSTKPVHLQLRALGSETRIDWLLDGRWIAQTVGGQTFQRDFPEPGTYILTALAEDGAWNRMQFRVLR
Sequences:
>Translated_796_residues MSMFVLPSLSASMFGRLRDDRALTWLRWSCAGLLSLLLLLDVLCPLPLPTSHDMALLVVARDGTPLRAFPDADGVWRYPA QLGQVSPLYVQALLTYEDRMFWRHPGVNPWALLRAGGLWLRYGHVVSGGSTLTMQAARILEPHGRTPWGKLKQLLRAVQL EVHLSKRQILQLYLERAPYGGTIQGVEAASWAYLGKSAARLSHAEAALLAVLPQSPSRLRPDRNPQLARQARDKVLARMA VLGVWSDEEVKDARLEPVVARALQPPMYAALLAQRLRVQRPHAARIVTTLDIDLQRTLEERVSTYFSPLPERTSAAVLVM DNQSLEARAYVGSVTFGDAKRLGHVDMVRAWRSPGSTLKPFLYGMALDQGLIHSESLLVDAPQHFGDYRPGNFDAAFTGP IGASSALRQSLNVPAVDLLERIGPARFATRLAHAGVQLRFPRGATPNLALILGGAGAQLQELVGAFSVFNRGGVAGRVRY TPEDPRIERRLISPGAAWIVREILAANPRPGYGRGTFDTAMRPSVAWKTGTSYGFRDAWALGSTRRYTVGVWVGRPDGTP LPGQYGAITALPLLFDVIDVLPRAPGDAVPEPMPASVEQVDICWPLGFAAASTPPELCRRRYSAYVLDGVVPPTFAERDA KLWRSGLERFQVDVRSGLRVRPDCRLPHLIREQQIARWPTLVIPWLDAVERRATHLPRLASDCSEDDRADAGVLYIDGLV EGATLQRPPGSTKPVHLQLRALGSETRIDWLLDGRWIAQTVGGQTFQRDFPEPGTYILTALAEDGAWNRMQFRVLR >Mature_795_residues SMFVLPSLSASMFGRLRDDRALTWLRWSCAGLLSLLLLLDVLCPLPLPTSHDMALLVVARDGTPLRAFPDADGVWRYPAQ LGQVSPLYVQALLTYEDRMFWRHPGVNPWALLRAGGLWLRYGHVVSGGSTLTMQAARILEPHGRTPWGKLKQLLRAVQLE VHLSKRQILQLYLERAPYGGTIQGVEAASWAYLGKSAARLSHAEAALLAVLPQSPSRLRPDRNPQLARQARDKVLARMAV LGVWSDEEVKDARLEPVVARALQPPMYAALLAQRLRVQRPHAARIVTTLDIDLQRTLEERVSTYFSPLPERTSAAVLVMD NQSLEARAYVGSVTFGDAKRLGHVDMVRAWRSPGSTLKPFLYGMALDQGLIHSESLLVDAPQHFGDYRPGNFDAAFTGPI GASSALRQSLNVPAVDLLERIGPARFATRLAHAGVQLRFPRGATPNLALILGGAGAQLQELVGAFSVFNRGGVAGRVRYT PEDPRIERRLISPGAAWIVREILAANPRPGYGRGTFDTAMRPSVAWKTGTSYGFRDAWALGSTRRYTVGVWVGRPDGTPL PGQYGAITALPLLFDVIDVLPRAPGDAVPEPMPASVEQVDICWPLGFAAASTPPELCRRRYSAYVLDGVVPPTFAERDAK LWRSGLERFQVDVRSGLRVRPDCRLPHLIREQQIARWPTLVIPWLDAVERRATHLPRLASDCSEDDRADAGVLYIDGLVE GATLQRPPGSTKPVHLQLRALGSETRIDWLLDGRWIAQTVGGQTFQRDFPEPGTYILTALAEDGAWNRMQFRVLR
Specific function: Cell wall formation. The enzyme has a penicillin- insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a transpeptidase C-terminal domain which may not be functional [H]
COG id: COG4953
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein PbpC
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1788867, Length=760, Percent_Identity=48.5526315789474, Blast_Score=652, Evalue=0.0, Organism=Escherichia coli, GI1786343, Length=590, Percent_Identity=26.9491525423729, Blast_Score=115, Evalue=8e-27, Organism=Escherichia coli, GI87082258, Length=303, Percent_Identity=30.3630363036304, Blast_Score=115, Evalue=1e-26, Organism=Escherichia coli, GI1789601, Length=178, Percent_Identity=30.8988764044944, Blast_Score=65, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011815 - InterPro: IPR009647 - InterPro: IPR001460 [H]
Pfam domain/function: PF06832 BiPBP_C; PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-
Molecular weight: Translated: 87929; Mature: 87798
Theoretical pI: Translated: 10.01; Mature: 10.01
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSMFVLPSLSASMFGRLRDDRALTWLRWSCAGLLSLLLLLDVLCPLPLPTSHDMALLVVA CCEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE RDGTPLRAFPDADGVWRYPAQLGQVSPLYVQALLTYEDRMFWRHPGVNPWALLRAGGLWL CCCCCCEECCCCCCCEECHHHHCCCCHHHHHHHHHHHHHHEEECCCCCHHHHHHCCCEEE RYGHVVSGGSTLTMQAARILEPHGRTPWGKLKQLLRAVQLEVHLSKRQILQLYLERAPYG EECEEECCCCEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC GTIQGVEAASWAYLGKSAARLSHAEAALLAVLPQSPSRLRPDRNPQLARQARDKVLARMA CCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHH VLGVWSDEEVKDARLEPVVARALQPPMYAALLAQRLRVQRPHAARIVTTLDIDLQRTLEE HHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHH RVSTYFSPLPERTSAAVLVMDNQSLEARAYVGSVTFGDAKRLGHVDMVRAWRSPGSTLKP HHHHHHCCCCCCCCEEEEEEECCCCEEEEEEEEEEECCHHHCCHHHHHHHHCCCCCHHHH FLYGMALDQGLIHSESLLVDAPQHFGDYRPGNFDAAFTGPIGASSALRQSLNVPAVDLLE HHHHHHHHCCCCCCCCEEEECHHHCCCCCCCCCCCEECCCCCCHHHHHHHCCCCHHHHHH RIGPARFATRLAHAGVQLRFPRGATPNLALILGGAGAQLQELVGAFSVFNRGGVAGRVRY HHCHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEE TPEDPRIERRLISPGAAWIVREILAANPRPGYGRGTFDTAMRPSVAWKTGTSYGFRDAWA CCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHCCCCCEEEECCCCCCCCHHHH LGSTRRYTVGVWVGRPDGTPLPGQYGAITALPLLFDVIDVLPRAPGDAVPEPMPASVEQV CCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEE DICWPLGFAAASTPPELCRRRYSAYVLDGVVPPTFAERDAKLWRSGLERFQVDVRSGLRV EEEECCCCCCCCCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE RPDCRLPHLIREQQIARWPTLVIPWLDAVERRATHLPRLASDCSEDDRADAGVLYIDGLV CCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEECCC EGATLQRPPGSTKPVHLQLRALGSETRIDWLLDGRWIAQTVGGQTFQRDFPEPGTYILTA CCCEECCCCCCCCCEEEEEEECCCCCCEEEEECCCHHHHHHCCCHHHHCCCCCCCEEEEE LAEDGAWNRMQFRVLR EECCCCCCCEEEEEEC >Mature Secondary Structure SMFVLPSLSASMFGRLRDDRALTWLRWSCAGLLSLLLLLDVLCPLPLPTSHDMALLVVA CEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE RDGTPLRAFPDADGVWRYPAQLGQVSPLYVQALLTYEDRMFWRHPGVNPWALLRAGGLWL CCCCCCEECCCCCCCEECHHHHCCCCHHHHHHHHHHHHHHEEECCCCCHHHHHHCCCEEE RYGHVVSGGSTLTMQAARILEPHGRTPWGKLKQLLRAVQLEVHLSKRQILQLYLERAPYG EECEEECCCCEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC GTIQGVEAASWAYLGKSAARLSHAEAALLAVLPQSPSRLRPDRNPQLARQARDKVLARMA CCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHH VLGVWSDEEVKDARLEPVVARALQPPMYAALLAQRLRVQRPHAARIVTTLDIDLQRTLEE HHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHH RVSTYFSPLPERTSAAVLVMDNQSLEARAYVGSVTFGDAKRLGHVDMVRAWRSPGSTLKP HHHHHHCCCCCCCCEEEEEEECCCCEEEEEEEEEEECCHHHCCHHHHHHHHCCCCCHHHH FLYGMALDQGLIHSESLLVDAPQHFGDYRPGNFDAAFTGPIGASSALRQSLNVPAVDLLE HHHHHHHHCCCCCCCCEEEECHHHCCCCCCCCCCCEECCCCCCHHHHHHHCCCCHHHHHH RIGPARFATRLAHAGVQLRFPRGATPNLALILGGAGAQLQELVGAFSVFNRGGVAGRVRY HHCHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEE TPEDPRIERRLISPGAAWIVREILAANPRPGYGRGTFDTAMRPSVAWKTGTSYGFRDAWA CCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHCCCCCEEEECCCCCCCCHHHH LGSTRRYTVGVWVGRPDGTPLPGQYGAITALPLLFDVIDVLPRAPGDAVPEPMPASVEQV CCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEE DICWPLGFAAASTPPELCRRRYSAYVLDGVVPPTFAERDAKLWRSGLERFQVDVRSGLRV EEEECCCCCCCCCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE RPDCRLPHLIREQQIARWPTLVIPWLDAVERRATHLPRLASDCSEDDRADAGVLYIDGLV CCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEECCC EGATLQRPPGSTKPVHLQLRALGSETRIDWLLDGRWIAQTVGGQTFQRDFPEPGTYILTA CCCEECCCCCCCCCEEEEEEECCCCCCEEEEECCCHHHHHHCCCHHHHCCCCCCCEEEEE LAEDGAWNRMQFRVLR EECCCCCCCEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10542235; 9205837; 9278503; 9841666 [H]