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The map label for this gene is fabH [H]

Identifier: 28198945

GI number: 28198945

Start: 1251445

End: 1252419

Strand: Reverse

Name: fabH [H]

Synonym: PD1048

Alternate gene names: 28198945

Gene position: 1252419-1251445 (Counterclockwise)

Preceding gene: 28198946

Following gene: 28198932

Centisome position: 49.7

GC content: 50.87

Gene sequence:

>975_bases
ATGAGCAAGCGGATCTTCGCTAGAATCGCAGGCACAGGCGGTTATTTGCCGGAAAAAGTGCTAACTAATAACGATCTGGC
CCATATCGTCGATACCAGCGATGAATGGATCCGCACTCGCACTGGTATCCGTGAGCGGCATATTGCTGCCGAAGGCGAAA
CGACCAGCGATTTGGCTTATGAGGCTGCGATACGTGCACTTGAAGCTGCTGAGGTGCGGTCCGCTGATTTGGATTTGATT
GTTGTCGGGACCACAACGCCGGACTTGATTTTTCCGTCTACTGCTTGCTTGTTACAGGCACGTCTTGGAGCTGTTGGTTG
TGGTGCGTTCGACGTGAATGCTGCATGTTCCGGTTTTGTATATGCGTTGAGCGTGGCAGAAAAATTTGTGTCTTCGGGTT
GCTCCAAAACAGTGTTAGTTGTGGGGGCCGATACCTTGACCCGAATTATCGATTGGAGTGACCGCACGACTTGCGTACTA
TTCGGGGATGGTGCCGGAGCGGTGGTGCTCAAGGCTGATGAAGATACAGGGATTCTCAGTACCCATCTGCATGCTGATGG
GAGCAAAAAAGAATTGTTGTGGGATCCTGTTGGTGTGTCAGTTGGTTTTGGTGAAGGTAAAGATTGCGGCGCGCTGTTGA
TGAAGGGAAATGAGGTGTTTAAATATGCCGTTAAAGCCCTTGATAGAGTGGTTGATGAGACGTTGGAAGCGAATCATCTG
GATAAGCACGAACTCGATTGGTTAATTCCTCACCAAGCAAACTTACGCATTATCGAAGCCACCGCAAGGCGTTTAGATAT
GTCGATGAATCAGGTGGTGGTCACGGTTGATCGTCACGGCAACACTTCCACGGCTTCGGTGCCACTCGCGCTTGACGAGG
CTATCCGTTCTGGTCGTGTGCAGCGTGGTCAGTTACTGCTCCTGGAAGCATTCGGCGGTGGTTTTACTTGGGGATCGGCG
TTACTGCGCTATTAA

Upstream 100 bases:

>100_bases
GATTAATTGAAGAGTAAAAAATCCTACTTGTTTACTGCATGTGCTTTGAAAGTCGCGTCCGTCCCGGCGCGGCTTTTTTA
ATAAATTTAGGAACTTCGAT

Downstream 100 bases:

>100_bases
TCCAATTTGCCAGCGTTTTTGGGTGGGACCTTTATCATAGTTAACGGCCACTAATCAACAATGAACAAATGTCCAGGGAA
TGTTTAGGGCGAGTTCCGCA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSKRIFARIAGTGGYLPEKVLTNNDLAHIVDTSDEWIRTRTGIRERHIAAEGETTSDLAYEAAIRALEAAEVRSADLDLI
VVGTTTPDLIFPSTACLLQARLGAVGCGAFDVNAACSGFVYALSVAEKFVSSGCSKTVLVVGADTLTRIIDWSDRTTCVL
FGDGAGAVVLKADEDTGILSTHLHADGSKKELLWDPVGVSVGFGEGKDCGALLMKGNEVFKYAVKALDRVVDETLEANHL
DKHELDWLIPHQANLRIIEATARRLDMSMNQVVVTVDRHGNTSTASVPLALDEAIRSGRVQRGQLLLLEAFGGGFTWGSA
LLRY

Sequences:

>Translated_324_residues
MSKRIFARIAGTGGYLPEKVLTNNDLAHIVDTSDEWIRTRTGIRERHIAAEGETTSDLAYEAAIRALEAAEVRSADLDLI
VVGTTTPDLIFPSTACLLQARLGAVGCGAFDVNAACSGFVYALSVAEKFVSSGCSKTVLVVGADTLTRIIDWSDRTTCVL
FGDGAGAVVLKADEDTGILSTHLHADGSKKELLWDPVGVSVGFGEGKDCGALLMKGNEVFKYAVKALDRVVDETLEANHL
DKHELDWLIPHQANLRIIEATARRLDMSMNQVVVTVDRHGNTSTASVPLALDEAIRSGRVQRGQLLLLEAFGGGFTWGSA
LLRY
>Mature_323_residues
SKRIFARIAGTGGYLPEKVLTNNDLAHIVDTSDEWIRTRTGIRERHIAAEGETTSDLAYEAAIRALEAAEVRSADLDLIV
VGTTTPDLIFPSTACLLQARLGAVGCGAFDVNAACSGFVYALSVAEKFVSSGCSKTVLVVGADTLTRIIDWSDRTTCVLF
GDGAGAVVLKADEDTGILSTHLHADGSKKELLWDPVGVSVGFGEGKDCGALLMKGNEVFKYAVKALDRVVDETLEANHLD
KHELDWLIPHQANLRIIEATARRLDMSMNQVVVTVDRHGNTSTASVPLALDEAIRSGRVQRGQLLLLEAFGGGFTWGSAL
LRY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=320, Percent_Identity=61.875, Blast_Score=394, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34786; Mature: 34655

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRIFARIAGTGGYLPEKVLTNNDLAHIVDTSDEWIRTRTGIRERHIAAEGETTSDLAY
CCCEEEEEEECCCCCCCCHHHCCCCEEEEECCCHHHHHHHCCCHHHEEECCCCCCHHHHH
EAAIRALEAAEVRSADLDLIVVGTTTPDLIFPSTACLLQARLGAVGCGAFDVNAACSGFV
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCEEECCCEECCHHHHHHH
YALSVAEKFVSSGCSKTVLVVGADTLTRIIDWSDRTTCVLFGDGAGAVVLKADEDTGILS
HHHHHHHHHHHCCCCCEEEEEECHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCEEE
THLHADGSKKELLWDPVGVSVGFGEGKDCGALLMKGNEVFKYAVKALDRVVDETLEANHL
EEEECCCCCCCEEECCCCEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCC
DKHELDWLIPHQANLRIIEATARRLDMSMNQVVVTVDRHGNTSTASVPLALDEAIRSGRV
CCCCCCEECCCCCCEEEEEEHHHHHCCCCCEEEEEEECCCCCCCCEECHHHHHHHHCCCC
QRGQLLLLEAFGGGFTWGSALLRY
CCCCEEEEEECCCCCHHHHHHHCC
>Mature Secondary Structure 
SKRIFARIAGTGGYLPEKVLTNNDLAHIVDTSDEWIRTRTGIRERHIAAEGETTSDLAY
CCEEEEEEECCCCCCCCHHHCCCCEEEEECCCHHHHHHHCCCHHHEEECCCCCCHHHHH
EAAIRALEAAEVRSADLDLIVVGTTTPDLIFPSTACLLQARLGAVGCGAFDVNAACSGFV
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCEEECCCEECCHHHHHHH
YALSVAEKFVSSGCSKTVLVVGADTLTRIIDWSDRTTCVLFGDGAGAVVLKADEDTGILS
HHHHHHHHHHHCCCCCEEEEEECHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCEEE
THLHADGSKKELLWDPVGVSVGFGEGKDCGALLMKGNEVFKYAVKALDRVVDETLEANHL
EEEECCCCCCCEEECCCCEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCC
DKHELDWLIPHQANLRIIEATARRLDMSMNQVVVTVDRHGNTSTASVPLALDEAIRSGRV
CCCCCCEECCCCCCEEEEEEHHHHHCCCCCEEEEEEECCCCCCCCEECHHHHHHHHCCCC
QRGQLLLLEAFGGGFTWGSALLRY
CCCCEEEEEECCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]