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The map label for this gene is ygcA [C]

Identifier: 62185452

GI number: 62185452

Start: 986480

End: 987685

Strand: Direct

Name: ygcA [C]

Synonym: CAB849

Alternate gene names: 62185452

Gene position: 986480-987685 (Clockwise)

Preceding gene: 62185451

Following gene: 62185453

Centisome position: 86.2

GC content: 39.72

Gene sequence:

>1206_bases
ATGCTTACAGTCTCCAATTGTAAACATCTAGGCATTTGCGGTGGGTGTTCCTCACCGCACTCTGCCTATGCAGACTCTTT
AAAAGCTAAAGAACGTATCTTACACGAGCTCTTTGCTCCTATTTTCCCTGCGTCAGATATTCTACCTATCATTCCATGCG
ATCCTCTTTTGCGGGGAAGAAATAAAATGGAATTTTCTTTTTTCCAAACTAAAGAGGGGGAGAAAAGTCTAGGATTCATT
ACTCCTACAAAACCGAAGCAAGGCATTCCCATTACAGAATGTCTTATGATTCACGAACATGCCATGGATATTCTAGAGAT
CACACGCACATGGTGGGACCGTCATCCTGAGATTACAGCTTACTACCCTCCCTTCAATAAAGGCTCTCTTTGCACCTTAA
CTGTACGTATTGGCAGCCCTGAACACACGCTCATGGTCATTCTCACAACATCTGCAAGAGAAGAATATGCCGTTGATAAA
AAGATAATTGAAGAATGGAAAACTCTGCTTTTAGATTCTGATCTTCCTATAGTTTCTATTGTATGGGAAGAACGCGTTAG
TGCGAAAAACGTTCCTACCTATTTCCGCTCTAACCTACTTTACGGAGAAGCATTTATTCAACAAAAGTTCGTCTTACCTA
AAGATGGAAATTCCGCTGTATTTCATGTGCGCCCTAGAAGCTTCTTTCAACCACAAACTCTTCAGGGAGCAAAAATCATA
GAAGTTGCCAAAGAGTTTATGGATCCACAACGATCGGAAACGCTCTTAGACCTCTATTGCGGTGCGGGAACTATAGGGAT
TATGCTTTCACAATATGTAAAAAAAGTTATAGGAGTAGAAATCGTCCCTGATGCTATAGATTCTGCAAAAGAAAATATCT
TAATAAATAAAAAAGAACATCTCATGGAAGTACATCTAGAGGATGTAAAAACTTTCTGTAAGCGGTATCAAGATCATCCT
TCTCCTGACGTTGCGATCATTGATCCCCCACGCTGTGGCATACAAAACAAAGTACTGAAATACTTAATAAGAATCGCCCC
TAGAAAAATTATTTATATCTCATGTAACCCAAAAATACAGTTTGTGGAGTGTTATAGCCTAATTGCTGCAGGTTACCGCA
TGAAAAAAGTCCAGCCTTTAGATCAATTTCCGCATTCTCCGCACTTAGAAAATATCATTTTGTTAGAAAGAGAAGGTCAC
CTCTAG

Upstream 100 bases:

>100_bases
TGTTTAACTGCTGAGTGGACGCATAGTCATTCTATCCCGCAGGCACGTGAATTTTGCACATAAAATTCGATTCTAAAATT
AGAGCCCTTACACATAGACC

Downstream 100 bases:

>100_bases
GAAAAGCATTGAATGCACGCTTCCTATTATGTTAACCTTTCTTTGAAATAACCGAAGTAAAGGTGGTTTAATGTTATCTC
GTTTATTCATGTGTTTTTTA

Product: putative RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MLTVSNCKHLGICGGCSSPHSAYADSLKAKERILHELFAPIFPASDILPIIPCDPLLRGRNKMEFSFFQTKEGEKSLGFI
TPTKPKQGIPITECLMIHEHAMDILEITRTWWDRHPEITAYYPPFNKGSLCTLTVRIGSPEHTLMVILTTSAREEYAVDK
KIIEEWKTLLLDSDLPIVSIVWEERVSAKNVPTYFRSNLLYGEAFIQQKFVLPKDGNSAVFHVRPRSFFQPQTLQGAKII
EVAKEFMDPQRSETLLDLYCGAGTIGIMLSQYVKKVIGVEIVPDAIDSAKENILINKKEHLMEVHLEDVKTFCKRYQDHP
SPDVAIIDPPRCGIQNKVLKYLIRIAPRKIIYISCNPKIQFVECYSLIAAGYRMKKVQPLDQFPHSPHLENIILLEREGH
L

Sequences:

>Translated_401_residues
MLTVSNCKHLGICGGCSSPHSAYADSLKAKERILHELFAPIFPASDILPIIPCDPLLRGRNKMEFSFFQTKEGEKSLGFI
TPTKPKQGIPITECLMIHEHAMDILEITRTWWDRHPEITAYYPPFNKGSLCTLTVRIGSPEHTLMVILTTSAREEYAVDK
KIIEEWKTLLLDSDLPIVSIVWEERVSAKNVPTYFRSNLLYGEAFIQQKFVLPKDGNSAVFHVRPRSFFQPQTLQGAKII
EVAKEFMDPQRSETLLDLYCGAGTIGIMLSQYVKKVIGVEIVPDAIDSAKENILINKKEHLMEVHLEDVKTFCKRYQDHP
SPDVAIIDPPRCGIQNKVLKYLIRIAPRKIIYISCNPKIQFVECYSLIAAGYRMKKVQPLDQFPHSPHLENIILLEREGH
L
>Mature_401_residues
MLTVSNCKHLGICGGCSSPHSAYADSLKAKERILHELFAPIFPASDILPIIPCDPLLRGRNKMEFSFFQTKEGEKSLGFI
TPTKPKQGIPITECLMIHEHAMDILEITRTWWDRHPEITAYYPPFNKGSLCTLTVRIGSPEHTLMVILTTSAREEYAVDK
KIIEEWKTLLLDSDLPIVSIVWEERVSAKNVPTYFRSNLLYGEAFIQQKFVLPKDGNSAVFHVRPRSFFQPQTLQGAKII
EVAKEFMDPQRSETLLDLYCGAGTIGIMLSQYVKKVIGVEIVPDAIDSAKENILINKKEHLMEVHLEDVKTFCKRYQDHP
SPDVAIIDPPRCGIQNKVLKYLIRIAPRKIIYISCNPKIQFVECYSLIAAGYRMKKVQPLDQFPHSPHLENIILLEREGH
L

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=199, Percent_Identity=32.6633165829146, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI51173878, Length=199, Percent_Identity=32.6633165829146, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI269784680, Length=383, Percent_Identity=24.0208877284595, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI269784676, Length=383, Percent_Identity=24.0208877284595, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI20149688, Length=383, Percent_Identity=24.0208877284595, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI269784678, Length=377, Percent_Identity=23.342175066313, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI1789148, Length=401, Percent_Identity=23.6907730673317, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1787083, Length=196, Percent_Identity=29.0816326530612, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790403, Length=200, Percent_Identity=26, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71997438, Length=165, Percent_Identity=29.6969696969697, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24666579, Length=427, Percent_Identity=25.9953161592506, Blast_Score=112, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010280 [H]

Pfam domain/function: PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 45668; Mature: 45668

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTVSNCKHLGICGGCSSPHSAYADSLKAKERILHELFAPIFPASDILPIIPCDPLLRGR
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCC
NKMEFSFFQTKEGEKSLGFITPTKPKQGIPITECLMIHEHAMDILEITRTWWDRHPEITA
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
YYPPFNKGSLCTLTVRIGSPEHTLMVILTTSAREEYAVDKKIIEEWKTLLLDSDLPIVSI
ECCCCCCCCEEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEE
VWEERVSAKNVPTYFRSNLLYGEAFIQQKFVLPKDGNSAVFHVRPRSFFQPQTLQGAKII
EEHHHHCCCCCCHHHHHCCHHHHHHHHHEECCCCCCCCCEEEECCCCCCCCCCCCCHHHH
EVAKEFMDPQRSETLLDLYCGAGTIGIMLSQYVKKVIGVEIVPDAIDSAKENILINKKEH
HHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCEECCHHHHHHHHCEEECCHHH
LMEVHLEDVKTFCKRYQDHPSPDVAIIDPPRCGIQNKVLKYLIRIAPRKIIYISCNPKIQ
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCCEE
FVECYSLIAAGYRMKKVQPLDQFPHSPHLENIILLEREGHL
HHHHHHHHHCCCHHHCCCCHHHCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MLTVSNCKHLGICGGCSSPHSAYADSLKAKERILHELFAPIFPASDILPIIPCDPLLRGR
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCC
NKMEFSFFQTKEGEKSLGFITPTKPKQGIPITECLMIHEHAMDILEITRTWWDRHPEITA
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
YYPPFNKGSLCTLTVRIGSPEHTLMVILTTSAREEYAVDKKIIEEWKTLLLDSDLPIVSI
ECCCCCCCCEEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEE
VWEERVSAKNVPTYFRSNLLYGEAFIQQKFVLPKDGNSAVFHVRPRSFFQPQTLQGAKII
EEHHHHCCCCCCHHHHHCCHHHHHHHHHEECCCCCCCCCEEEECCCCCCCCCCCCCHHHH
EVAKEFMDPQRSETLLDLYCGAGTIGIMLSQYVKKVIGVEIVPDAIDSAKENILINKKEH
HHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCEECCHHHHHHHHCEEECCHHH
LMEVHLEDVKTFCKRYQDHPSPDVAIIDPPRCGIQNKVLKYLIRIAPRKIIYISCNPKIQ
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCCEE
FVECYSLIAAGYRMKKVQPLDQFPHSPHLENIILLEREGHL
HHHHHHHHHCCCHHHCCCCHHHCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]