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The map label for this gene is aaxB

Identifier: 62185310

GI number: 62185310

Start: 808162

End: 808749

Strand: Direct

Name: aaxB

Synonym: CAB697

Alternate gene names: 62185310

Gene position: 808162-808749 (Clockwise)

Preceding gene: 62185309

Following gene: 62185311

Centisome position: 70.62

GC content: 39.8

Gene sequence:

>588_bases
ATGCCTTACGGAACACGCTACCCGACATTAGCTTTCCATACGGGAGGAGTCGGTGAATCTGATGATGGAATGCCTCCTCA
ACCTTTTGAAACTTTCTGTTATGACTCAGCTCTATTACAAGCAAAAATTGAGAATTTTAATATCGTCCCTTACACATCAG
TACTACCTAAAGAACTCTTTGGCAATATTGTTCCTGTAGATCAATGTGTCAAATTCTTCAAACATGGTGCTGTTTTAGAA
GTCATCATGGCTGGACGCGGAGCTTCCACAGTAGAAGGCACGCATGCTATTACTACAGGTGTAGGTATTTGCTGGGGACA
AGACAAAAATGGCGAGCTCATCGGTGGATGGGCAGCAGAATATGTAGAGTTTTTCCCTACATGGATTAACGATGAAATCG
CAGAATCCCATGCTAAAATGTGGTTGAAGAAATCCCTTCAACATGAACTAGATCTTCGCTCAGTTGTCAAACATAGTGAA
TTTCAATATTTCCATAACTACATTAACATTAAGCAAAAATATGGTTTCTCATTAACTGCATTAGGGTTTCTCAACTTTGA
AAATGCCGATCCGGTAACAATTAAGTAA

Upstream 100 bases:

>100_bases
CCTGCACGAAGACCCGATAAACGTGCCGCTAAAGTTTACGGCGTCCGAGCGAATTTCTCTACCTAACATCCTACAACTTG
ATATCCTTAGGAGTTTGTAC

Downstream 100 bases:

>100_bases
GGAGAATACATGATTTCTAATGGGAGTAAATCCGGGAAAAATCTCGGAGCCATAGCTTTAGCAGGCATGGTCATTAGCTC
CATGATTGGGGGAGGGATTT

Product: hypothetical protein

Products: NA

Alternate protein names: PvlArgDC; Biodegradative arginine decarboxylase

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MPYGTRYPTLAFHTGGVGESDDGMPPQPFETFCYDSALLQAKIENFNIVPYTSVLPKELFGNIVPVDQCVKFFKHGAVLE
VIMAGRGASTVEGTHAITTGVGICWGQDKNGELIGGWAAEYVEFFPTWINDEIAESHAKMWLKKSLQHELDLRSVVKHSE
FQYFHNYINIKQKYGFSLTALGFLNFENADPVTIK

Sequences:

>Translated_195_residues
MPYGTRYPTLAFHTGGVGESDDGMPPQPFETFCYDSALLQAKIENFNIVPYTSVLPKELFGNIVPVDQCVKFFKHGAVLE
VIMAGRGASTVEGTHAITTGVGICWGQDKNGELIGGWAAEYVEFFPTWINDEIAESHAKMWLKKSLQHELDLRSVVKHSE
FQYFHNYINIKQKYGFSLTALGFLNFENADPVTIK
>Mature_194_residues
PYGTRYPTLAFHTGGVGESDDGMPPQPFETFCYDSALLQAKIENFNIVPYTSVLPKELFGNIVPVDQCVKFFKHGAVLEV
IMAGRGASTVEGTHAITTGVGICWGQDKNGELIGGWAAEYVEFFPTWINDEIAESHAKMWLKKSLQHELDLRSVVKHSEF
QYFHNYINIKQKYGFSLTALGFLNFENADPVTIK

Specific function: Part of the AaxABC system, catalyzes the decarboxylation of L-arginine. The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response

COG id: COG1945

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyruvoyl-dependent arginine decarboxylase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AAXB_CHLAB (Q5L5E7)

Other databases:

- EMBL:   CR848038
- RefSeq:   YP_220095.1
- GeneID:   3337603
- GenomeReviews:   CR848038_GR
- KEGG:   cab:CAB697
- HOGENOM:   HBG414056
- OMA:   WIDDEIA
- ProtClustDB:   CLSK403032
- BioCyc:   CABO218497:CAB697-MONOMER
- GO:   GO:0005737
- GO:   GO:0009405
- InterPro:   IPR016104
- InterPro:   IPR016105
- InterPro:   IPR002724
- Gene3D:   G3DSA:3.50.20.10
- ProDom:   PD010449

Pfam domain/function: PF01862 PvlArgDC; SSF56271 His_carbxylase

EC number: =4.1.1.19

Molecular weight: Translated: 21831; Mature: 21700

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYGTRYPTLAFHTGGVGESDDGMPPQPFETFCYDSALLQAKIENFNIVPYTSVLPKELF
CCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
GNIVPVDQCVKFFKHGAVLEVIMAGRGASTVEGTHAITTGVGICWGQDKNGELIGGWAAE
CCCCCHHHHHHHHHCCHHEEHHHCCCCCCCCCCCHHHHHCCEEEECCCCCCCEECHHHHH
YVEFFPTWINDEIAESHAKMWLKKSLQHELDLRSVVKHSEFQYFHNYINIKQKYGFSLTA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LGFLNFENADPVTIK
EEEEECCCCCCCEEC
>Mature Secondary Structure 
PYGTRYPTLAFHTGGVGESDDGMPPQPFETFCYDSALLQAKIENFNIVPYTSVLPKELF
CCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
GNIVPVDQCVKFFKHGAVLEVIMAGRGASTVEGTHAITTGVGICWGQDKNGELIGGWAAE
CCCCCHHHHHHHHHCCHHEEHHHCCCCCCCCCCCHHHHHCCEEEECCCCCCCEECHHHHH
YVEFFPTWINDEIAESHAKMWLKKSLQHELDLRSVVKHSEFQYFHNYINIKQKYGFSLTA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LGFLNFENADPVTIK
EEEEECCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA