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The map label for this gene is aroM [H]

Identifier: 62185304

GI number: 62185304

Start: 801682

End: 802203

Strand: Direct

Name: aroM [H]

Synonym: CAB691

Alternate gene names: 62185304

Gene position: 801682-802203 (Clockwise)

Preceding gene: 62185303

Following gene: 62185305

Centisome position: 70.05

GC content: 40.8

Gene sequence:

>522_bases
ATGAACATATTTCTCTGCGGCCTGCCGACAGTAGGCAAGACGTTGTTTGGCAAGGCTCTCGCTAAATATCTTTCGGTGCC
TTTCTTTGATGTCGATGATTTAATCGTAAGTAACTACGGCAATAAGCTATATCCCTCGGCCTGCGAAATATTCCAGGCTA
TTGGAGAACAAGAGTTTACAAAATTAGAAATTGCAGCTCTCCGTTCTCCCTGCCTAGATCATAGTGTTACAGCTTTAGGT
GGAGGCACTATCATGCATCAAGAAGCATGTGATATAATTAAACATCGAGGAACGCTAGTTTATCTATCCCTGCCTATGGC
TCAGATTCGTGAAAGACTCTTAAAACGTGGTCTCCCTGAAAGATTAAAACGCGCTCCAAATATGGAAGAAATCTTACAAC
AACGTATAGAGCGTATGCAACGCATCTGTGACTATCACTTCCCTCTTGATGAGGTAAATCTTTTAGATGAACGTTCATTA
TTCTCTGCGTGTGAATCTTTTACTACTTTACTAAATCAATGA

Upstream 100 bases:

>100_bases
TCTGGGGATAGCATTATCTATGATACCGATTGCGTAAAAAAAACTTTCCCGAATTTCATCCAGATTCTAAATTCCTTGCA
TACGAATATCCAGGAACATT

Downstream 100 bases:

>100_bases
GAAATCGCTTTGGTTCTTTATTTTCTCTAACGACATGGGGAGAATCTCATGGACCTTGTCTTGGGGTTGTTATCGACGGG
TGCCCTGCAGGGCTACAACT

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MNIFLCGLPTVGKTLFGKALAKYLSVPFFDVDDLIVSNYGNKLYPSACEIFQAIGEQEFTKLEIAALRSPCLDHSVTALG
GGTIMHQEACDIIKHRGTLVYLSLPMAQIRERLLKRGLPERLKRAPNMEEILQQRIERMQRICDYHFPLDEVNLLDERSL
FSACESFTTLLNQ

Sequences:

>Translated_173_residues
MNIFLCGLPTVGKTLFGKALAKYLSVPFFDVDDLIVSNYGNKLYPSACEIFQAIGEQEFTKLEIAALRSPCLDHSVTALG
GGTIMHQEACDIIKHRGTLVYLSLPMAQIRERLLKRGLPERLKRAPNMEEILQQRIERMQRICDYHFPLDEVNLLDERSL
FSACESFTTLLNQ
>Mature_173_residues
MNIFLCGLPTVGKTLFGKALAKYLSVPFFDVDDLIVSNYGNKLYPSACEIFQAIGEQEFTKLEIAALRSPCLDHSVTALG
GGTIMHQEACDIIKHRGTLVYLSLPMAQIRERLLKRGLPERLKRAPNMEEILQQRIERMQRICDYHFPLDEVNLLDERSL
FSACESFTTLLNQ

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 19637; Mature: 19637

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFLCGLPTVGKTLFGKALAKYLSVPFFDVDDLIVSNYGNKLYPSACEIFQAIGEQEFT
CCEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCHHHHH
KLEIAALRSPCLDHSVTALGGGTIMHQEACDIIKHRGTLVYLSLPMAQIRERLLKRGLPE
HHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCHH
RLKRAPNMEEILQQRIERMQRICDYHFPLDEVNLLDERSLFSACESFTTLLNQ
HHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIFLCGLPTVGKTLFGKALAKYLSVPFFDVDDLIVSNYGNKLYPSACEIFQAIGEQEFT
CCEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCHHHHH
KLEIAALRSPCLDHSVTALGGGTIMHQEACDIIKHRGTLVYLSLPMAQIRERLLKRGLPE
HHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCHH
RLKRAPNMEEILQQRIERMQRICDYHFPLDEVNLLDERSLFSACESFTTLLNQ
HHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]