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The map label for this gene is purQ [H]

Identifier: 23501727

GI number: 23501727

Start: 817488

End: 818159

Strand: Reverse

Name: purQ [H]

Synonym: BR0840

Alternate gene names: 23501727

Gene position: 818159-817488 (Counterclockwise)

Preceding gene: 23501728

Following gene: 23501726

Centisome position: 38.82

GC content: 60.71

Gene sequence:

>672_bases
ATGAAATCCGCAGTCATTCTTCTTCCCGGCCTCAACCGTGATCGCGATATGATCGCGGCACTCACCAAGATCACCGGGCA
GGCTCCTGTGACGGTCTGGCAGACTGACACCAGCATTCCAGACGATGTGGATCTGATCCTTATTCCCGGCGGTTTTTCCT
ATGGTGACTATCTGCGCTGCGGCGCAATTGCCGCGCGTATGCCGGTGATGCAGGCCGTGCGCGAGAAGGCCGACAAGGGC
GTGATGGTCATGGGCGTGTGCAACGGCTTCCAGATCCTCCTTGAGGCCGGGCTTCTGCCGGGCGCGCTGATGCGCAATGC
CTCGCTGAAATTCGTCTGCCGCGAAGTGAAGCTCGAAGTAACCAACGCCAACACGTCGTTCACACGCGGTTACAAGCCGG
GCCAGATCATCCGCTGCCCGGTCGCGCATCACGACGGCAATTATTTCGCCGACGCCGAAACGCTGAAGCGTCTCGAAGGC
GAAGGCCAGGTCGTGTTCCGCTATGCCGAAGGCACCAACCCGAACGGATCGGTCAACGACATTGCCGGTATCGTCAATGC
GCGCGGCAATGTGCTGGGCATGATGCCGCATCCGGAAAACCTGATCGAAGCCGCCCATGGCGGCGATGACGGCCGGGCGC
TTTTTGCAGGCGCACTCGGCATCACAGCCTGA

Upstream 100 bases:

>100_bases
GAAGCGGACCTCAAGGCCATGTGCGAGAAGCTGCTCGCCAACACCGTGATTGAAGATTATTCTATCGCCATCGCCTGAGC
CCAAAAAGGAAGCAGACGCC

Downstream 100 bases:

>100_bases
CAGATCTTGCATATATGAAAACGGGCGGCCCAATCGGAGCCGCCTTTTTTATTGCGCCTGCTTCATCTCAAAACTGCACT
GGCAAAGCATCTGTTTTCAT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKSAVILLPGLNRDRDMIAALTKITGQAPVTVWQTDTSIPDDVDLILIPGGFSYGDYLRCGAIAARMPVMQAVREKADKG
VMVMGVCNGFQILLEAGLLPGALMRNASLKFVCREVKLEVTNANTSFTRGYKPGQIIRCPVAHHDGNYFADAETLKRLEG
EGQVVFRYAEGTNPNGSVNDIAGIVNARGNVLGMMPHPENLIEAAHGGDDGRALFAGALGITA

Sequences:

>Translated_223_residues
MKSAVILLPGLNRDRDMIAALTKITGQAPVTVWQTDTSIPDDVDLILIPGGFSYGDYLRCGAIAARMPVMQAVREKADKG
VMVMGVCNGFQILLEAGLLPGALMRNASLKFVCREVKLEVTNANTSFTRGYKPGQIIRCPVAHHDGNYFADAETLKRLEG
EGQVVFRYAEGTNPNGSVNDIAGIVNARGNVLGMMPHPENLIEAAHGGDDGRALFAGALGITA
>Mature_223_residues
MKSAVILLPGLNRDRDMIAALTKITGQAPVTVWQTDTSIPDDVDLILIPGGFSYGDYLRCGAIAARMPVMQAVREKADKG
VMVMGVCNGFQILLEAGLLPGALMRNASLKFVCREVKLEVTNANTSFTRGYKPGQIIRCPVAHHDGNYFADAETLKRLEG
EGQVVFRYAEGTNPNGSVNDIAGIVNARGNVLGMMPHPENLIEAAHGGDDGRALFAGALGITA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=227, Percent_Identity=30.8370044052863, Blast_Score=74, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6321498, Length=203, Percent_Identity=32.512315270936, Blast_Score=75, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24582111, Length=232, Percent_Identity=30.6034482758621, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24582109, Length=232, Percent_Identity=30.6034482758621, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17137292, Length=232, Percent_Identity=30.6034482758621, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 23769; Mature: 23769

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSAVILLPGLNRDRDMIAALTKITGQAPVTVWQTDTSIPDDVDLILIPGGFSYGDYLRC
CCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCHHHH
GAIAARMPVMQAVREKADKGVMVMGVCNGFQILLEAGLLPGALMRNASLKFVCREVKLEV
HHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCHHHHCCCCCEEEEEEEEEEE
TNANTSFTRGYKPGQIIRCPVAHHDGNYFADAETLKRLEGEGQVVFRYAEGTNPNGSVND
ECCCCCCCCCCCCCCEEEEEEEECCCCEEECHHHHHHHCCCCEEEEEEECCCCCCCCHHH
IAGIVNARGNVLGMMPHPENLIEAAHGGDDGRALFAGALGITA
HHHHHCCCCCEEEECCCCHHHHHHHCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MKSAVILLPGLNRDRDMIAALTKITGQAPVTVWQTDTSIPDDVDLILIPGGFSYGDYLRC
CCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCHHHH
GAIAARMPVMQAVREKADKGVMVMGVCNGFQILLEAGLLPGALMRNASLKFVCREVKLEV
HHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCHHHHCCCCCEEEEEEEEEEE
TNANTSFTRGYKPGQIIRCPVAHHDGNYFADAETLKRLEGEGQVVFRYAEGTNPNGSVND
ECCCCCCCCCCCCCCEEEEEEEECCCCEEECHHHHHHHCCCCEEEEEEECCCCCCCCHHH
IAGIVNARGNVLGMMPHPENLIEAAHGGDDGRALFAGALGITA
HHHHHCCCCCEEEECCCCHHHHHHHCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA