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The map label for this gene is speB [H]

Identifier: 23501676

GI number: 23501676

Start: 770788

End: 771738

Strand: Reverse

Name: speB [H]

Synonym: BR0789

Alternate gene names: 23501676

Gene position: 771738-770788 (Counterclockwise)

Preceding gene: 23501677

Following gene: 23501675

Centisome position: 36.61

GC content: 59.31

Gene sequence:

>951_bases
ATGCCTTCAAAGACCATCGACCATGCGATCACTGCCCGCAGCCTGACCAGTGCGGCCACCGACCCAACCCATGCGGGCGT
CTTGTCCTTCATGCGGCGCACTTACTCCAAGTCGCTCAAAGGCGCGGAAGCAGTTGTCTGGGGCATTCCTTTCGATGCCG
CCGTTTCCAACCGGCCCGGCGCACGCTTCGGCCCGCAGGCGATCCGGCGCGCCTCGGCGATCTTCGACAACGATCCGCAA
TATCCGTTCGAGCGTGATCTTTTCGAGAATCTCGCTGTCATCGATTATGGCGACTGCCTGCTCGACTATGGCAATCACAC
CAAGACACCCTCCACCATCGAGCGTGAAGCAGCAAAAATCCTGAAATCCGATGCATTTCTGCTGACGCTCGGCGGCGATC
ATTTCATCACATGGCCGCTTCTCAAGGCCCATGCCGCAAAATACGGCCCCCTCGCTCTGGTGCAGTTCGATGCGCATCAG
GATACATGGTTCAATGATGGCAGGCGGATCGACCACGGCTCCTTCGTGGCCCGCGCGGTGCGCGACGGCATCATCGATCC
CGACCTTTCGATCCAGATTGGCATCCGCACGCATGCGCCGGAAGATTGCGGCATCAGGATCATTTATGGCCACGAGGTCG
AGGATATGCCAGCGGCGGCGATTGCCGATGCAATCCTGAAACGCACCAATGGCAGGAAAGCCTATCTGACCTTCGACATT
GACTGTCTCGATCCGGCTTTTGCGCCGGGAACCGGCACGCCGGTTGCAGGCGGCCCCTCCTCGGCAAAGATGCTGTCTGT
CCTGCGCAAGCTGACGGCTCTTGACTTCGTGGGCGCCGATGTAGTCGAGGTTGCACCGGCCTATGACCATGCCGATATAA
CAGCCATCGCGGGAGCGACGATCGCAATGTATTATCTGGGCCTTCTGGGCGAACGGAAAGAACGACGATGA

Upstream 100 bases:

>100_bases
GAAGCGTTAATCCTTATCGCTTTGGACTTACAGAAAAGCGGGCCTTCGGGTCCGCTTTTTTGCTATGTAATAGGAGACTC
AAGCCAGCACGGAAGCGGCC

Downstream 100 bases:

>100_bases
AGCGTCGCGCTTGTTCATAGATTGATTCAAGCGGCTCGAAAACTGATTCCGAATATCGCCGTAACTTTCTGAATTCAAAG
GCAAAACGCATGAAACCGAA

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MPSKTIDHAITARSLTSAATDPTHAGVLSFMRRTYSKSLKGAEAVVWGIPFDAAVSNRPGARFGPQAIRRASAIFDNDPQ
YPFERDLFENLAVIDYGDCLLDYGNHTKTPSTIEREAAKILKSDAFLLTLGGDHFITWPLLKAHAAKYGPLALVQFDAHQ
DTWFNDGRRIDHGSFVARAVRDGIIDPDLSIQIGIRTHAPEDCGIRIIYGHEVEDMPAAAIADAILKRTNGRKAYLTFDI
DCLDPAFAPGTGTPVAGGPSSAKMLSVLRKLTALDFVGADVVEVAPAYDHADITAIAGATIAMYYLGLLGERKERR

Sequences:

>Translated_316_residues
MPSKTIDHAITARSLTSAATDPTHAGVLSFMRRTYSKSLKGAEAVVWGIPFDAAVSNRPGARFGPQAIRRASAIFDNDPQ
YPFERDLFENLAVIDYGDCLLDYGNHTKTPSTIEREAAKILKSDAFLLTLGGDHFITWPLLKAHAAKYGPLALVQFDAHQ
DTWFNDGRRIDHGSFVARAVRDGIIDPDLSIQIGIRTHAPEDCGIRIIYGHEVEDMPAAAIADAILKRTNGRKAYLTFDI
DCLDPAFAPGTGTPVAGGPSSAKMLSVLRKLTALDFVGADVVEVAPAYDHADITAIAGATIAMYYLGLLGERKERR
>Mature_315_residues
PSKTIDHAITARSLTSAATDPTHAGVLSFMRRTYSKSLKGAEAVVWGIPFDAAVSNRPGARFGPQAIRRASAIFDNDPQY
PFERDLFENLAVIDYGDCLLDYGNHTKTPSTIEREAAKILKSDAFLLTLGGDHFITWPLLKAHAAKYGPLALVQFDAHQD
TWFNDGRRIDHGSFVARAVRDGIIDPDLSIQIGIRTHAPEDCGIRIIYGHEVEDMPAAAIADAILKRTNGRKAYLTFDID
CLDPAFAPGTGTPVAGGPSSAKMLSVLRKLTALDFVGADVVEVAPAYDHADITAIAGATIAMYYLGLLGERKERR

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=294, Percent_Identity=36.0544217687075, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI10947139, Length=282, Percent_Identity=27.3049645390071, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1789306, Length=253, Percent_Identity=44.6640316205534, Blast_Score=219, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 34295; Mature: 34164

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSKTIDHAITARSLTSAATDPTHAGVLSFMRRTYSKSLKGAEAVVWGIPFDAAVSNRPG
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHCCCCCC
ARFGPQAIRRASAIFDNDPQYPFERDLFENLAVIDYGDCLLDYGNHTKTPSTIEREAAKI
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEECCHHHEECCCCCCCCHHHHHHHHHH
LKSDAFLLTLGGDHFITWPLLKAHAAKYGPLALVQFDAHQDTWFNDGRRIDHGSFVARAV
HHCCCEEEEECCCCEEEHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEECHHHHHHHHH
RDGIIDPDLSIQIGIRTHAPEDCGIRIIYGHEVEDMPAAAIADAILKRTNGRKAYLTFDI
HCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEE
DCLDPAFAPGTGTPVAGGPSSAKMLSVLRKLTALDFVGADVVEVAPAYDHADITAIAGAT
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHH
IAMYYLGLLGERKERR
HHHHHHHHHCCHHCCC
>Mature Secondary Structure 
PSKTIDHAITARSLTSAATDPTHAGVLSFMRRTYSKSLKGAEAVVWGIPFDAAVSNRPG
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHCCCCCC
ARFGPQAIRRASAIFDNDPQYPFERDLFENLAVIDYGDCLLDYGNHTKTPSTIEREAAKI
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEECCHHHEECCCCCCCCHHHHHHHHHH
LKSDAFLLTLGGDHFITWPLLKAHAAKYGPLALVQFDAHQDTWFNDGRRIDHGSFVARAV
HHCCCEEEEECCCCEEEHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEECHHHHHHHHH
RDGIIDPDLSIQIGIRTHAPEDCGIRIIYGHEVEDMPAAAIADAILKRTNGRKAYLTFDI
HCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEE
DCLDPAFAPGTGTPVAGGPSSAKMLSVLRKLTALDFVGADVVEVAPAYDHADITAIAGAT
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHH
IAMYYLGLLGERKERR
HHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]