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The map label for this gene is yheS [H]

Identifier: 23501579

GI number: 23501579

Start: 679395

End: 681278

Strand: Reverse

Name: yheS [H]

Synonym: BR0692

Alternate gene names: 23501579

Gene position: 681278-679395 (Counterclockwise)

Preceding gene: 23501580

Following gene: 23501575

Centisome position: 32.32

GC content: 58.7

Gene sequence:

>1884_bases
ATGCTTATCCTTGACGATATTTCCGTACGAATTGCCGGACGCCTATTGATCGACCACGCCAGCGTGACGCTGCCTGCGGG
ATCGAAGACAGGCTTTGTCGGCCGCAACGGCACCGGCAAATCAACCCTGTTTCGCGTGATTACGGGCGATCTGGCGCCGG
AAACCGGCAGCATATCGTTTCCGAAGAACACCCGCATCGGCCAGGTGGCGCAGGAAGCGCCGGGCACTGAGGAACCGCTG
ATCGAAATCGTCATGAAGGCGGACAAGGAGCGCGCCGCCCTTCTGGAAGAAGCAGCCACCGCCACAGACCCGCACCGGAT
TGCGGAAATCCACACGCGGCTTGCCGATATCGACGCGCATTCGGCAGAAGCGCGCGCGGGAGCCATCCTGTCCGGCCTTG
GCTTCGATGCACAAGCGCAGCGCCAGCCTGCTTCCGCCTTTTCCGGCGGGTGGCGGATGCGCGTGGCGCTTGCCGCCGTT
CTGTTTGCCGAACCCGATCTTCTTCTTCTCGATGAGCCGACCAACTATCTCGACCTTGAAGGCGTCTTGTGGCTGGTGGA
TTATGTGAAGCGTTATCCGCACACGGTCATCATCATCAGCCATGATCGCGATCTGTTGAACTCGGCCACATCATCGATCA
TGCATCTCGACCAGAAGAAGATCAGCTTCTGGCGCGGCAATTACGATCAATTTGAGCGGCAGCGGCATGAAATGCTGGAA
CTTCAGCAAAAGGCCCATGCCAGGCAGGAAGCCCACCGCAAGCACATGGAAAGCTTCGTGGAGCGTTTCCGCGCCAAGGC
GACCAAGGCGCGCCAGGCGCAATCACGCCTGAAAGCATTGCAAAAGCTGAAGCCCATCGAGCTTTATGTGGAAAGCCATG
TGCAGCCTTTCCGCTTTCCCGATGCGGAAAAGAAGGCCGCCTCGCCCATTATCGCGCTTGACGGCGCGGATGTGGGCTAT
GTGCCGGGAAAGCCGGTGCTGCGCAATGTGACGCTGCGCATCGACAATGACGACCGCATCGCACTGCTTGGCTCAAACGG
CAACGGTAAATCCACGCTCGCCAAGCTGATTGCCGGGCGATTGGCCCCGGAAAAAGGCACCCTTACCATTTCGCCCAATC
TGAAGGTTGCATTTTTCGCGCAGCACCAGCTTGACGATCTGGTGCCGGAAGACAATGCGATCGAGCATGTGCGCAAGCTG
ATGCCGGCCGAGCCGGAAGCCAGAGTGCGTGCCCGTGTCGCGCAGATGGGCCTTTCGACGGAAAAAATGCTGACACCCGC
CAAGGATTTGTCGGGCGGCGAAAAGGCGCGCCTTCTCATGGGCCTTGCGACATTCCACGGCCCGAACCTGCTCATCCTCG
ACGAGCCGACAAACCATCTCGATATCGACAGCCGCGAGGAGCTGGTGCACGCGCTCAACGCCTTCAACGGCGCGGTGATC
CTGATTGCCCACGACCGCCACCTTATCGAAGCCACGATGGAGCGGCTCTGGCTTGTGCGCGAAGGCGGCGTGAAACCATT
TGAAGGCGATCTTGATGAATATCGCCAGATCGTGCTGGCAGACGCGAAGGGCGAGCCTGCTGCGGACCGCGACGAAGGGC
CGAAGGTGAACAAGGCCGAGCAGCGCAAGCTTGCAGCACAAAAGCGCGAAGCCCTTGCGCCGTTGCAGAAAAAGATCAAG
GAAACCGAAAGCTTGATCCAGAAATTGCAGAAACAGATTCAAGACTTCAGCATGCAGTTGGAAGACCCGGCTCTTTATGA
GAAGGAACCGCAGAAAGCCATTCGCATCAACAAGGATATGAGCGACGCCAAATCAACCCTTGCCGAAGCCGAGGATAAGT
GGCTGGAGCTTTCAGCCGAATATGAGGAAGCCATGGCGGAGTGA

Upstream 100 bases:

>100_bases
ACCATCGCTGGATCTTGTGCATTTTCTGCAACAGGAGACGGGACGCCGCTTCGCTTGAGGCTTGCGGAAAAAGCGGAAGC
CGTGCAAAAGCCCTCTTACC

Downstream 100 bases:

>100_bases
TCCGCGCCAGCCCTTAGCACTCCAGTTGCATTCTTCGTGATGCCGGGCTGCAAATGGCGACTTTTGGAACAGGCTCTTAT
GTTTGGGGGCGGCGAAGGCG

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MLILDDISVRIAGRLLIDHASVTLPAGSKTGFVGRNGTGKSTLFRVITGDLAPETGSISFPKNTRIGQVAQEAPGTEEPL
IEIVMKADKERAALLEEAATATDPHRIAEIHTRLADIDAHSAEARAGAILSGLGFDAQAQRQPASAFSGGWRMRVALAAV
LFAEPDLLLLDEPTNYLDLEGVLWLVDYVKRYPHTVIIISHDRDLLNSATSSIMHLDQKKISFWRGNYDQFERQRHEMLE
LQQKAHARQEAHRKHMESFVERFRAKATKARQAQSRLKALQKLKPIELYVESHVQPFRFPDAEKKAASPIIALDGADVGY
VPGKPVLRNVTLRIDNDDRIALLGSNGNGKSTLAKLIAGRLAPEKGTLTISPNLKVAFFAQHQLDDLVPEDNAIEHVRKL
MPAEPEARVRARVAQMGLSTEKMLTPAKDLSGGEKARLLMGLATFHGPNLLILDEPTNHLDIDSREELVHALNAFNGAVI
LIAHDRHLIEATMERLWLVREGGVKPFEGDLDEYRQIVLADAKGEPAADRDEGPKVNKAEQRKLAAQKREALAPLQKKIK
ETESLIQKLQKQIQDFSMQLEDPALYEKEPQKAIRINKDMSDAKSTLAEAEDKWLELSAEYEEAMAE

Sequences:

>Translated_627_residues
MLILDDISVRIAGRLLIDHASVTLPAGSKTGFVGRNGTGKSTLFRVITGDLAPETGSISFPKNTRIGQVAQEAPGTEEPL
IEIVMKADKERAALLEEAATATDPHRIAEIHTRLADIDAHSAEARAGAILSGLGFDAQAQRQPASAFSGGWRMRVALAAV
LFAEPDLLLLDEPTNYLDLEGVLWLVDYVKRYPHTVIIISHDRDLLNSATSSIMHLDQKKISFWRGNYDQFERQRHEMLE
LQQKAHARQEAHRKHMESFVERFRAKATKARQAQSRLKALQKLKPIELYVESHVQPFRFPDAEKKAASPIIALDGADVGY
VPGKPVLRNVTLRIDNDDRIALLGSNGNGKSTLAKLIAGRLAPEKGTLTISPNLKVAFFAQHQLDDLVPEDNAIEHVRKL
MPAEPEARVRARVAQMGLSTEKMLTPAKDLSGGEKARLLMGLATFHGPNLLILDEPTNHLDIDSREELVHALNAFNGAVI
LIAHDRHLIEATMERLWLVREGGVKPFEGDLDEYRQIVLADAKGEPAADRDEGPKVNKAEQRKLAAQKREALAPLQKKIK
ETESLIQKLQKQIQDFSMQLEDPALYEKEPQKAIRINKDMSDAKSTLAEAEDKWLELSAEYEEAMAE
>Mature_627_residues
MLILDDISVRIAGRLLIDHASVTLPAGSKTGFVGRNGTGKSTLFRVITGDLAPETGSISFPKNTRIGQVAQEAPGTEEPL
IEIVMKADKERAALLEEAATATDPHRIAEIHTRLADIDAHSAEARAGAILSGLGFDAQAQRQPASAFSGGWRMRVALAAV
LFAEPDLLLLDEPTNYLDLEGVLWLVDYVKRYPHTVIIISHDRDLLNSATSSIMHLDQKKISFWRGNYDQFERQRHEMLE
LQQKAHARQEAHRKHMESFVERFRAKATKARQAQSRLKALQKLKPIELYVESHVQPFRFPDAEKKAASPIIALDGADVGY
VPGKPVLRNVTLRIDNDDRIALLGSNGNGKSTLAKLIAGRLAPEKGTLTISPNLKVAFFAQHQLDDLVPEDNAIEHVRKL
MPAEPEARVRARVAQMGLSTEKMLTPAKDLSGGEKARLLMGLATFHGPNLLILDEPTNHLDIDSREELVHALNAFNGAVI
LIAHDRHLIEATMERLWLVREGGVKPFEGDLDEYRQIVLADAKGEPAADRDEGPKVNKAEQRKLAAQKREALAPLQKKIK
ETESLIQKLQKQIQDFSMQLEDPALYEKEPQKAIRINKDMSDAKSTLAEAEDKWLELSAEYEEAMAE

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=529, Percent_Identity=39.3194706994329, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI10947137, Length=525, Percent_Identity=35.6190476190476, Blast_Score=323, Evalue=3e-88,
Organism=Homo sapiens, GI27881506, Length=525, Percent_Identity=35.6190476190476, Blast_Score=323, Evalue=4e-88,
Organism=Homo sapiens, GI69354671, Length=556, Percent_Identity=35.0719424460432, Blast_Score=293, Evalue=4e-79,
Organism=Homo sapiens, GI10947135, Length=556, Percent_Identity=35.0719424460432, Blast_Score=292, Evalue=5e-79,
Organism=Escherichia coli, GI1789751, Length=639, Percent_Identity=39.906103286385, Blast_Score=470, Evalue=1e-133,
Organism=Escherichia coli, GI1787041, Length=524, Percent_Identity=34.1603053435114, Blast_Score=332, Evalue=4e-92,
Organism=Escherichia coli, GI1787182, Length=630, Percent_Identity=29.2063492063492, Blast_Score=255, Evalue=6e-69,
Organism=Escherichia coli, GI2367384, Length=528, Percent_Identity=30.4924242424242, Blast_Score=196, Evalue=5e-51,
Organism=Escherichia coli, GI1788165, Length=197, Percent_Identity=27.9187817258883, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87081834, Length=202, Percent_Identity=31.1881188118812, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789891, Length=219, Percent_Identity=26.9406392694064, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1786345, Length=214, Percent_Identity=29.4392523364486, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788506, Length=229, Percent_Identity=25.764192139738, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786319, Length=203, Percent_Identity=33.4975369458128, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI145693107, Length=453, Percent_Identity=22.9580573951435, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787164, Length=187, Percent_Identity=31.5508021390374, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1788053, Length=242, Percent_Identity=28.099173553719, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787370, Length=222, Percent_Identity=26.5765765765766, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787758, Length=210, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI48994943, Length=228, Percent_Identity=26.7543859649123, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1789586, Length=207, Percent_Identity=29.4685990338164, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1788897, Length=199, Percent_Identity=30.1507537688442, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=534, Percent_Identity=37.4531835205993, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17555318, Length=525, Percent_Identity=34.8571428571429, Blast_Score=335, Evalue=6e-92,
Organism=Caenorhabditis elegans, GI17559834, Length=560, Percent_Identity=34.8214285714286, Blast_Score=328, Evalue=4e-90,
Organism=Caenorhabditis elegans, GI115533608, Length=221, Percent_Identity=25.7918552036199, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=545, Percent_Identity=35.9633027522936, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6320874, Length=526, Percent_Identity=30.9885931558935, Blast_Score=292, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6325030, Length=438, Percent_Identity=28.7671232876712, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6323278, Length=425, Percent_Identity=26.5882352941176, Blast_Score=133, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6324314, Length=424, Percent_Identity=24.7641509433962, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24666836, Length=531, Percent_Identity=37.6647834274953, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24642252, Length=522, Percent_Identity=35.2490421455939, Blast_Score=336, Evalue=3e-92,
Organism=Drosophila melanogaster, GI18859989, Length=522, Percent_Identity=35.2490421455939, Blast_Score=336, Evalue=3e-92,
Organism=Drosophila melanogaster, GI24641342, Length=542, Percent_Identity=34.5018450184502, Blast_Score=325, Evalue=5e-89,
Organism=Drosophila melanogaster, GI24666092, Length=203, Percent_Identity=29.064039408867, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007184, Length=155, Percent_Identity=31.6129032258064, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221500365, Length=155, Percent_Identity=31.6129032258064, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 69645; Mature: 69645

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILDDISVRIAGRLLIDHASVTLPAGSKTGFVGRNGTGKSTLFRVITGDLAPETGSISF
CEEECCCHHEEEEEEEEECCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
PKNTRIGQVAQEAPGTEEPLIEIVMKADKERAALLEEAATATDPHRIAEIHTRLADIDAH
CCCCCHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
SAEARAGAILSGLGFDAQAQRQPASAFSGGWRMRVALAAVLFAEPDLLLLDEPTNYLDLE
CCHHHHHHHHHCCCCCCHHHCCCHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCEECHH
GVLWLVDYVKRYPHTVIIISHDRDLLNSATSSIMHLDQKKISFWRGNYDQFERQRHEMLE
HHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQQKAHARQEAHRKHMESFVERFRAKATKARQAQSRLKALQKLKPIELYVESHVQPFRFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCC
DAEKKAASPIIALDGADVGYVPGKPVLRNVTLRIDNDDRIALLGSNGNGKSTLAKLIAGR
CCHHHHCCCEEEECCCCCCCCCCCCCEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHH
LAPEKGTLTISPNLKVAFFAQHQLDDLVPEDNAIEHVRKLMPAEPEARVRARVAQMGLST
CCCCCCEEEECCCCEEEEEEHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCH
EKMLTPAKDLSGGEKARLLMGLATFHGPNLLILDEPTNHLDIDSREELVHALNAFNGAVI
HHHCCCHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEE
LIAHDRHLIEATMERLWLVREGGVKPFEGDLDEYRQIVLADAKGEPAADRDEGPKVNKAE
EEECCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEEEEECCCCCCCCCCCCCCCCCHHH
QRKLAAQKREALAPLQKKIKETESLIQKLQKQIQDFSMQLEDPALYEKEPQKAIRINKDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEECCCH
SDAKSTLAEAEDKWLELSAEYEEAMAE
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLILDDISVRIAGRLLIDHASVTLPAGSKTGFVGRNGTGKSTLFRVITGDLAPETGSISF
CEEECCCHHEEEEEEEEECCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
PKNTRIGQVAQEAPGTEEPLIEIVMKADKERAALLEEAATATDPHRIAEIHTRLADIDAH
CCCCCHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
SAEARAGAILSGLGFDAQAQRQPASAFSGGWRMRVALAAVLFAEPDLLLLDEPTNYLDLE
CCHHHHHHHHHCCCCCCHHHCCCHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCEECHH
GVLWLVDYVKRYPHTVIIISHDRDLLNSATSSIMHLDQKKISFWRGNYDQFERQRHEMLE
HHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQQKAHARQEAHRKHMESFVERFRAKATKARQAQSRLKALQKLKPIELYVESHVQPFRFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCC
DAEKKAASPIIALDGADVGYVPGKPVLRNVTLRIDNDDRIALLGSNGNGKSTLAKLIAGR
CCHHHHCCCEEEECCCCCCCCCCCCCEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHH
LAPEKGTLTISPNLKVAFFAQHQLDDLVPEDNAIEHVRKLMPAEPEARVRARVAQMGLST
CCCCCCEEEECCCCEEEEEEHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCH
EKMLTPAKDLSGGEKARLLMGLATFHGPNLLILDEPTNHLDIDSREELVHALNAFNGAVI
HHHCCCHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEE
LIAHDRHLIEATMERLWLVREGGVKPFEGDLDEYRQIVLADAKGEPAADRDEGPKVNKAE
EEECCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEEEEECCCCCCCCCCCCCCCCCHHH
QRKLAAQKREALAPLQKKIKETESLIQKLQKQIQDFSMQLEDPALYEKEPQKAIRINKDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEECCCH
SDAKSTLAEAEDKWLELSAEYEEAMAE
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]