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The map label for this gene is xylR [H]

Identifier: 23100880

GI number: 23100880

Start: 3562940

End: 3564148

Strand: Reverse

Name: xylR [H]

Synonym: OB3425

Alternate gene names: 23100880

Gene position: 3564148-3562940 (Counterclockwise)

Preceding gene: 23100881

Following gene: 23100879

Centisome position: 98.17

GC content: 31.76

Gene sequence:

>1209_bases
GTGTCTAGAACAGGGAATTTAAAATTGATACAAGAATTAAATAGGTCATTAATTTTAGATACGATTAGAAAGAAAGGTCC
TATTTCAAGAAGTGATATAGCAAAAAAACTAACGATTAGCCCTACTACTGTTACCACTGCTGTTAGCGAATTAATCGAAG
GAAAGATAGTATATGAAGATGGTGTTGGGAATTCAAATGGCGGTAGAAAACCAGTATTACTCCGTTTTAATCCTGATACA
CATTCTATTATAGGAGTATCTATCACAAATTCGAAAATAAAAATTGCAGAAATGAATTTAGAAGGAAAGGTTAAAAAAAA
GAGTGTAGAGATAACTAATAATGAACAAGGTGAAGATATTATTAAGCTTGTAATAGAGACTTTAAAAACTTTTATCAAAA
ATGAGAAGGTTAATTTGGACTATTGTGAAGGTGTCTCTATTATTACACCAGGAATTGTGAATTCGGAAGAAGGGTGCATT
TCATATAATTCACATCTTGGCTTATATAATATCCCTCTTAAGAAGATGGTTGAATCCACCATTGGTTTACCAACATTTCT
TGAAAATGATGTTAATGCGTTTGTATCTGCTGAGAGTTATTTTGGTTCTTATAATCATTACAATAGTATTTTATTTTTAA
CGATTGGAGATGGTATTGGTTCAGGAATTATGATTAATGACAGTATTTATAAGGGTTACAAGGGAAGTGCTGGTGAGATA
GGACATACAACAGTCGTTCCAGGGGGGATTAAATGCAAGTGTGGAAATAGTGGATGTGTAGAGAATTATGTAAATTGGCC
TTCCATTCATTCTCGAATTGTATCAGCAATAATTACTAAAGGACGTGATACGTTAATTAAAAATTATATTGGAAATGACT
TTACTAAGATAACACCAGACATGTTTGTTTTGGCTATTCGTGAAAATGACGAGTTATGTAAGGAAATAATGGACGATATG
GTTAATTATCTATCTATCACTATTGTTAATGCTATTCATACGCTAAGTCCTGAATTAATTATTTTAAGTGGAGCTATTAT
TCATGGAAATCAGGTGTTTATAGATCAATTACAGGAGGAGGTAAAGAAAAGATTATTACCTATTATTAGGGAAGATGTTA
ACTTCCAAAGTACTTCATTAGGACCTGATTTTGATTTATTAGGGGCTGCTTCTGTAATTTTACAGGGACGTTTTCGATTT
CAATTGTAA

Upstream 100 bases:

>100_bases
TAAATAATACGGATAAGTTACAAATTATAAAATGATACGCTTCAATATTTTTAAAACTAATTTCAACCAAAAAATAAAGT
TTAAAAAGAGGTTAAATATT

Downstream 100 bases:

>100_bases
GAATGGGTAAAAGATAATGAATTCAGGAAACATAATAAAATTTTGGAGGTATATCATGAAAAAATTAACTATTCTAATTG
TATTGTTAATGGTTGGTTTC

Product: transcriptional repressor of the xylose operon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSRTGNLKLIQELNRSLILDTIRKKGPISRSDIAKKLTISPTTVTTAVSELIEGKIVYEDGVGNSNGGRKPVLLRFNPDT
HSIIGVSITNSKIKIAEMNLEGKVKKKSVEITNNEQGEDIIKLVIETLKTFIKNEKVNLDYCEGVSIITPGIVNSEEGCI
SYNSHLGLYNIPLKKMVESTIGLPTFLENDVNAFVSAESYFGSYNHYNSILFLTIGDGIGSGIMINDSIYKGYKGSAGEI
GHTTVVPGGIKCKCGNSGCVENYVNWPSIHSRIVSAIITKGRDTLIKNYIGNDFTKITPDMFVLAIRENDELCKEIMDDM
VNYLSITIVNAIHTLSPELIILSGAIIHGNQVFIDQLQEEVKKRLLPIIREDVNFQSTSLGPDFDLLGAASVILQGRFRF
QL

Sequences:

>Translated_402_residues
MSRTGNLKLIQELNRSLILDTIRKKGPISRSDIAKKLTISPTTVTTAVSELIEGKIVYEDGVGNSNGGRKPVLLRFNPDT
HSIIGVSITNSKIKIAEMNLEGKVKKKSVEITNNEQGEDIIKLVIETLKTFIKNEKVNLDYCEGVSIITPGIVNSEEGCI
SYNSHLGLYNIPLKKMVESTIGLPTFLENDVNAFVSAESYFGSYNHYNSILFLTIGDGIGSGIMINDSIYKGYKGSAGEI
GHTTVVPGGIKCKCGNSGCVENYVNWPSIHSRIVSAIITKGRDTLIKNYIGNDFTKITPDMFVLAIRENDELCKEIMDDM
VNYLSITIVNAIHTLSPELIILSGAIIHGNQVFIDQLQEEVKKRLLPIIREDVNFQSTSLGPDFDLLGAASVILQGRFRF
QL
>Mature_401_residues
SRTGNLKLIQELNRSLILDTIRKKGPISRSDIAKKLTISPTTVTTAVSELIEGKIVYEDGVGNSNGGRKPVLLRFNPDTH
SIIGVSITNSKIKIAEMNLEGKVKKKSVEITNNEQGEDIIKLVIETLKTFIKNEKVNLDYCEGVSIITPGIVNSEEGCIS
YNSHLGLYNIPLKKMVESTIGLPTFLENDVNAFVSAESYFGSYNHYNSILFLTIGDGIGSGIMINDSIYKGYKGSAGEIG
HTTVVPGGIKCKCGNSGCVENYVNWPSIHSRIVSAIITKGRDTLIKNYIGNDFTKITPDMFVLAIRENDELCKEIMDDMV
NYLSITIVNAIHTLSPELIILSGAIIHGNQVFIDQLQEEVKKRLLPIIREDVNFQSTSLGPDFDLLGAASVILQGRFRFQ
L

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=321, Percent_Identity=26.1682242990654, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI298566315, Length=321, Percent_Identity=26.1682242990654, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI190014632, Length=321, Percent_Identity=26.1682242990654, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI4885285, Length=321, Percent_Identity=26.1682242990654, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1786891, Length=385, Percent_Identity=25.4545454545455, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1787878, Length=393, Percent_Identity=22.3918575063613, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI87082127, Length=346, Percent_Identity=22.8323699421965, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787363, Length=240, Percent_Identity=22.5, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081733, Length=251, Percent_Identity=20.3187250996016, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44234; Mature: 44102

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00962 RIBOSOMAL_S2_1 ; PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTGNLKLIQELNRSLILDTIRKKGPISRSDIAKKLTISPTTVTTAVSELIEGKIVYED
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEEECCHHHHHHHHHHHCCEEEEEC
GVGNSNGGRKPVLLRFNPDTHSIIGVSITNSKIKIAEMNLEGKVKKKSVEITNNEQGEDI
CCCCCCCCCCCEEEEECCCCCEEEEEEEECCEEEEEEECCCCCEEEEEEEECCCCCHHHH
IKLVIETLKTFIKNEKVNLDYCEGVSIITPGIVNSEEGCISYNSHLGLYNIPLKKMVEST
HHHHHHHHHHHHCCCCCCCCHHCCCEEECCCCCCCCCCCEEECCCCCEEECCHHHHHHHH
IGLPTFLENDVNAFVSAESYFGSYNHYNSILFLTIGDGIGSGIMINDSIYKGYKGSAGEI
CCCCHHHHCCHHHEEEHHHHCCCCCCCCEEEEEEECCCCCCCEEEECHHHCCCCCCCCCC
GHTTVVPGGIKCKCGNSGCVENYVNWPSIHSRIVSAIITKGRDTLIKNYIGNDFTKITPD
CCEEECCCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEECCC
MFVLAIRENDELCKEIMDDMVNYLSITIVNAIHTLSPELIILSGAIIHGNQVFIDQLQEE
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHH
VKKRLLPIIREDVNFQSTSLGPDFDLLGAASVILQGRFRFQL
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCEEEECC
>Mature Secondary Structure 
SRTGNLKLIQELNRSLILDTIRKKGPISRSDIAKKLTISPTTVTTAVSELIEGKIVYED
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEEECCHHHHHHHHHHHCCEEEEEC
GVGNSNGGRKPVLLRFNPDTHSIIGVSITNSKIKIAEMNLEGKVKKKSVEITNNEQGEDI
CCCCCCCCCCCEEEEECCCCCEEEEEEEECCEEEEEEECCCCCEEEEEEEECCCCCHHHH
IKLVIETLKTFIKNEKVNLDYCEGVSIITPGIVNSEEGCISYNSHLGLYNIPLKKMVEST
HHHHHHHHHHHHCCCCCCCCHHCCCEEECCCCCCCCCCCEEECCCCCEEECCHHHHHHHH
IGLPTFLENDVNAFVSAESYFGSYNHYNSILFLTIGDGIGSGIMINDSIYKGYKGSAGEI
CCCCHHHHCCHHHEEEHHHHCCCCCCCCEEEEEEECCCCCCCEEEECHHHCCCCCCCCCC
GHTTVVPGGIKCKCGNSGCVENYVNWPSIHSRIVSAIITKGRDTLIKNYIGNDFTKITPD
CCEEECCCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEECCC
MFVLAIRENDELCKEIMDDMVNYLSITIVNAIHTLSPELIILSGAIIHGNQVFIDQLQEE
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHH
VKKRLLPIIREDVNFQSTSLGPDFDLLGAASVILQGRFRFQL
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8920183 [H]