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The map label for this gene is acyII [H]

Identifier: 23100760

GI number: 23100760

Start: 3443199

End: 3445601

Strand: Reverse

Name: acyII [H]

Synonym: OB3305

Alternate gene names: 23100760

Gene position: 3445601-3443199 (Counterclockwise)

Preceding gene: 23100761

Following gene: 23100759

Centisome position: 94.91

GC content: 46.94

Gene sequence:

>2403_bases
ATGGGGGAAAGACAGAGAGAACAAGTGTCGCAACCAAAGAAAAAGCGACGCATTCGTACAAAGAAGATACTGCTGGGTGG
GTTAGGATCTATTTTTTTGCTTGCACTTATTGCGTTTTTATTTGTAAACGGATACATAAATAAATCACTCCCGCAGACAG
AAGGCACAATGGAGCTTCCAATGCTGGATAACGAAGTAACCGTGATTACTGATGAGGATGGAGTGCCGCATATTCAAGCG
GAGACTGCCCGGGATATGTATATTGCACAGGGATATATTCAGGCGGATCGTCGAATGTTTCAGATGGAATTATCGCGAAG
ACAAGCCTCTGGCACATTAAGTGAGGTTGTCGGGGAAGACGCGCTGAATCAGGATAAATATTTTCGCACGCTTGGGCTGA
GAAGGGCCGCAGAGAAATCGTATGAGGTGTACTCGGAAGAATCCGTCGAGGTGCTGGAGTGGTTTTCAACGGGGGTGAAT
GCCTACATGGAAGAAGCCAAAGCGAATAATAGCTTGCCTGTGGAGTTTACGCTAATGGACTTTGAGCCGGAAGAATGGAC
ACCTGTCGATTCATTGACAATTGGAAAATTTATGGCATTTGACCTCGGCGGACATTGGCAGCAGCAAGCGTTCAACTATT
ACCTTTTGGACAATTATGAACAAGAAAAAGCTTATGAGCTGTTCCCATCCTATCCGGAAAATAAACCAACAATAATTCAG
GATGAGGAAATAGATATCGCGGCGAGTTTTGAGCATGCGGTTATTCCGCATCCATTCAATGGCAGCAACAACTGGGTGGT
GAGCGGAGATAAGACAGCGTCTGGAATGCCATTATTGGCAGACGACCCGCATCTCGGGCTGGCAACGCCATCGATCTGGC
TACAGATGCATTTGGAGTCAGGAGATGGACTGAATGTGAGCGGGGTTATTTTTGCGGGTGTCCCTGGCATTATCCTTGGT
CATAATGAGCAAATCGCTTGGGGGGTGACCAATACGGGACCAGACGTGCAGCAATTATATATTGAGCAACGTAACCCGGA
CAACCCACATGAATTCCTTTTTGAAGACGAGTGGGAAGAAGCGACCGTTATGGAAGAGCCAATTAAAGTGAAAGATGGTG
AAACGGTGGATTATGAAGTGGTCGAGACGAGACACGGGCCGATTGTTTCCGAGTTTGCCTCTGAATCTGGAAAGGATACC
GTACTTTCCTTACGATGGACGGCGCTCGATGCCAGCACAGAGCTCGAAGCGATTATGGAAATGAACCGAGCAACGGGCTG
GGAGGAATTTGAACAGGGGTTAGAAAAGTTCCTCGTACCAGCGCAGAATTTTGTTTTTGCCTCCAACGATGGAACCATTG
CCTATAAAGCAAATGGAAAAATTCCAATTTATGAGGACGGCCAAGATGCATTATTGCCACTGAATGGCTGGGAAGCAGAG
AGTGAATGGCAAGGCTATATCCCTTATGATGAATTGCCGACCGTCATTAACCCGGAAAAAGGATTTATCGCAACGGCTAA
CAATCAGATTGCACCCGACAGTTACCCGTACCATATCAGTAACGTGTGGGCGCAACCATATCGCTATGAACGGATTGCGG
AAGTGCTTGAATCGGGTGATAATTTTACAGCAGAAGATATGCAAGATTTACAAATGGATCAGACCGACTTACGTGCAAGG
GAGTTCGTACCGATTTTTCAAAAAGTGCTGGAAGATACAGAACTTACCGAGCAAGAAAAAGAAGCATTGGATGCACTGTC
GGAATGGGATTTCGTCGCAGATAAGGATGCACCACAGCCACTTATCTTTGAACATTGGATGCAAGCAATTCAAAGCACCA
TTTATCAACAGGAAATACCACAAGTGATGCGAGAATTATTCTCCACACAATCCCAATCAACCGAAAACGTATTACGCAAA
GCCGCGAGCGGTCAGAAATCACAATGGATAGAAGACAAAGGCGGCATCGAAGTAGTATTGCATGACGCACTAGAGAACAC
GATGGAAAAACTAACAGAAACCTATGGAGAAGACCTATCCGCCTGGAAATGGGGCGACTACCACCAAGTGCAATTCCACC
ACCCATTATCGAGCGTCAGTCCTTTACTCGCATTTTTCCTCAACAATGAAGATGCAATCCCCGTTGGCGGCAGTGGTGTA
ACGCCAATGGCAACAAGCTATGATAAAGAAACTGGAGAAGTCGATCACGGTGCTTCCTGGCGATTCGTCATTGACACAAG
CGACATGCAATCGGGCTACCATATCGTCGGCCCAGGCCAGGACGGACATTTCCGAAGCGATTGGTATCACGACCAAATGA
ACGACTGGGTCGAAGGAAATTTTCACGAGACCAGGTTGGATGGAGCTGAGGGTGAGGAATTGGTGTTAGAGCCTGGGGAG
TAG

Upstream 100 bases:

>100_bases
GAAATTCCCACATGCGTCTTGCCCATCTGCGCCCAAAGTGCTATGATTCTCTTAAACTAAAATATTTCTAAAAATTTTGT
GAATAAGAGAGGTCTTGCTA

Downstream 100 bases:

>100_bases
ACTTATATAACATGAGGCTGTACCATTTGAAAGGTACAGCCTTTTCTTGCGGGATTCTATTACAAGTTGTTGTTTTATTA
TAAATTGCTTACAGATAGGT

Product: penicillin acylase

Products: NA

Alternate protein names: Cephalosporin acylase II; Penicillin acylase II; Penicillin amidase II; Penicillin acylase II small subunit; Penicillin acylase II large subunit [H]

Number of amino acids: Translated: 800; Mature: 799

Protein sequence:

>800_residues
MGERQREQVSQPKKKRRIRTKKILLGGLGSIFLLALIAFLFVNGYINKSLPQTEGTMELPMLDNEVTVITDEDGVPHIQA
ETARDMYIAQGYIQADRRMFQMELSRRQASGTLSEVVGEDALNQDKYFRTLGLRRAAEKSYEVYSEESVEVLEWFSTGVN
AYMEEAKANNSLPVEFTLMDFEPEEWTPVDSLTIGKFMAFDLGGHWQQQAFNYYLLDNYEQEKAYELFPSYPENKPTIIQ
DEEIDIAASFEHAVIPHPFNGSNNWVVSGDKTASGMPLLADDPHLGLATPSIWLQMHLESGDGLNVSGVIFAGVPGIILG
HNEQIAWGVTNTGPDVQQLYIEQRNPDNPHEFLFEDEWEEATVMEEPIKVKDGETVDYEVVETRHGPIVSEFASESGKDT
VLSLRWTALDASTELEAIMEMNRATGWEEFEQGLEKFLVPAQNFVFASNDGTIAYKANGKIPIYEDGQDALLPLNGWEAE
SEWQGYIPYDELPTVINPEKGFIATANNQIAPDSYPYHISNVWAQPYRYERIAEVLESGDNFTAEDMQDLQMDQTDLRAR
EFVPIFQKVLEDTELTEQEKEALDALSEWDFVADKDAPQPLIFEHWMQAIQSTIYQQEIPQVMRELFSTQSQSTENVLRK
AASGQKSQWIEDKGGIEVVLHDALENTMEKLTETYGEDLSAWKWGDYHQVQFHHPLSSVSPLLAFFLNNEDAIPVGGSGV
TPMATSYDKETGEVDHGASWRFVIDTSDMQSGYHIVGPGQDGHFRSDWYHDQMNDWVEGNFHETRLDGAEGEELVLEPGE

Sequences:

>Translated_800_residues
MGERQREQVSQPKKKRRIRTKKILLGGLGSIFLLALIAFLFVNGYINKSLPQTEGTMELPMLDNEVTVITDEDGVPHIQA
ETARDMYIAQGYIQADRRMFQMELSRRQASGTLSEVVGEDALNQDKYFRTLGLRRAAEKSYEVYSEESVEVLEWFSTGVN
AYMEEAKANNSLPVEFTLMDFEPEEWTPVDSLTIGKFMAFDLGGHWQQQAFNYYLLDNYEQEKAYELFPSYPENKPTIIQ
DEEIDIAASFEHAVIPHPFNGSNNWVVSGDKTASGMPLLADDPHLGLATPSIWLQMHLESGDGLNVSGVIFAGVPGIILG
HNEQIAWGVTNTGPDVQQLYIEQRNPDNPHEFLFEDEWEEATVMEEPIKVKDGETVDYEVVETRHGPIVSEFASESGKDT
VLSLRWTALDASTELEAIMEMNRATGWEEFEQGLEKFLVPAQNFVFASNDGTIAYKANGKIPIYEDGQDALLPLNGWEAE
SEWQGYIPYDELPTVINPEKGFIATANNQIAPDSYPYHISNVWAQPYRYERIAEVLESGDNFTAEDMQDLQMDQTDLRAR
EFVPIFQKVLEDTELTEQEKEALDALSEWDFVADKDAPQPLIFEHWMQAIQSTIYQQEIPQVMRELFSTQSQSTENVLRK
AASGQKSQWIEDKGGIEVVLHDALENTMEKLTETYGEDLSAWKWGDYHQVQFHHPLSSVSPLLAFFLNNEDAIPVGGSGV
TPMATSYDKETGEVDHGASWRFVIDTSDMQSGYHIVGPGQDGHFRSDWYHDQMNDWVEGNFHETRLDGAEGEELVLEPGE
>Mature_799_residues
GERQREQVSQPKKKRRIRTKKILLGGLGSIFLLALIAFLFVNGYINKSLPQTEGTMELPMLDNEVTVITDEDGVPHIQAE
TARDMYIAQGYIQADRRMFQMELSRRQASGTLSEVVGEDALNQDKYFRTLGLRRAAEKSYEVYSEESVEVLEWFSTGVNA
YMEEAKANNSLPVEFTLMDFEPEEWTPVDSLTIGKFMAFDLGGHWQQQAFNYYLLDNYEQEKAYELFPSYPENKPTIIQD
EEIDIAASFEHAVIPHPFNGSNNWVVSGDKTASGMPLLADDPHLGLATPSIWLQMHLESGDGLNVSGVIFAGVPGIILGH
NEQIAWGVTNTGPDVQQLYIEQRNPDNPHEFLFEDEWEEATVMEEPIKVKDGETVDYEVVETRHGPIVSEFASESGKDTV
LSLRWTALDASTELEAIMEMNRATGWEEFEQGLEKFLVPAQNFVFASNDGTIAYKANGKIPIYEDGQDALLPLNGWEAES
EWQGYIPYDELPTVINPEKGFIATANNQIAPDSYPYHISNVWAQPYRYERIAEVLESGDNFTAEDMQDLQMDQTDLRARE
FVPIFQKVLEDTELTEQEKEALDALSEWDFVADKDAPQPLIFEHWMQAIQSTIYQQEIPQVMRELFSTQSQSTENVLRKA
ASGQKSQWIEDKGGIEVVLHDALENTMEKLTETYGEDLSAWKWGDYHQVQFHHPLSSVSPLLAFFLNNEDAIPVGGSGVT
PMATSYDKETGEVDHGASWRFVIDTSDMQSGYHIVGPGQDGHFRSDWYHDQMNDWVEGNFHETRLDGAEGEELVLEPGE

Specific function: Unknown

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.11 [H]

Molecular weight: Translated: 90598; Mature: 90467

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGERQREQVSQPKKKRRIRTKKILLGGLGSIFLLALIAFLFVNGYINKSLPQTEGTMELP
CCCHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECC
MLDNEVTVITDEDGVPHIQAETARDMYIAQGYIQADRRMFQMELSRRQASGTLSEVVGED
EECCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHH
ALNQDKYFRTLGLRRAAEKSYEVYSEESVEVLEWFSTGVNAYMEEAKANNSLPVEFTLMD
HCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
FEPEEWTPVDSLTIGKFMAFDLGGHWQQQAFNYYLLDNYEQEKAYELFPSYPENKPTIIQ
CCCCCCCCCCCEEHHHHEEEECCCCHHHHHCCEEEECCCCHHHHHHHCCCCCCCCCCEEE
DEEIDIAASFEHAVIPHPFNGSNNWVVSGDKTASGMPLLADDPHLGLATPSIWLQMHLES
CCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCEEECCCCCCCCCCEEEEEEEECC
GDGLNVSGVIFAGVPGIILGHNEQIAWGVTNTGPDVQQLYIEQRNPDNPHEFLFEDEWEE
CCCCCCCEEEEECCCEEEEECCCEEEEECCCCCCCHHHHHHHCCCCCCHHHCCCCCCCCH
ATVMEEPIKVKDGETVDYEVVETRHGPIVSEFASESGKDTVLSLRWTALDASTELEAIME
HHHHCCCEEECCCCCCEEEEEECCCCCHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHHH
MNRATGWEEFEQGLEKFLVPAQNFVFASNDGTIAYKANGKIPIYEDGQDALLPLNGWEAE
HHHCCCHHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCEEEEECCCCCEEECCCCCCC
SEWQGYIPYDELPTVINPEKGFIATANNQIAPDSYPYHISNVWAQPYRYERIAEVLESGD
CCCCCCCCHHHCCCCCCCCCCEEEECCCCCCCCCCCEEHHHHHCCCHHHHHHHHHHHCCC
NFTAEDMQDLQMDQTDLRAREFVPIFQKVLEDTELTEQEKEALDALSEWDFVADKDAPQP
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LIFEHWMQAIQSTIYQQEIPQVMRELFSTQSQSTENVLRKAASGQKSQWIEDKGGIEVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCCCCCEEEEE
HDALENTMEKLTETYGEDLSAWKWGDYHQVQFHHPLSSVSPLLAFFLNNEDAIPVGGSGV
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCC
TPMATSYDKETGEVDHGASWRFVIDTSDMQSGYHIVGPGQDGHFRSDWYHDQMNDWVEGN
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCC
FHETRLDGAEGEELVLEPGE
CCEEECCCCCCCEEEECCCC
>Mature Secondary Structure 
GERQREQVSQPKKKRRIRTKKILLGGLGSIFLLALIAFLFVNGYINKSLPQTEGTMELP
CCHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECC
MLDNEVTVITDEDGVPHIQAETARDMYIAQGYIQADRRMFQMELSRRQASGTLSEVVGED
EECCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHH
ALNQDKYFRTLGLRRAAEKSYEVYSEESVEVLEWFSTGVNAYMEEAKANNSLPVEFTLMD
HCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
FEPEEWTPVDSLTIGKFMAFDLGGHWQQQAFNYYLLDNYEQEKAYELFPSYPENKPTIIQ
CCCCCCCCCCCEEHHHHEEEECCCCHHHHHCCEEEECCCCHHHHHHHCCCCCCCCCCEEE
DEEIDIAASFEHAVIPHPFNGSNNWVVSGDKTASGMPLLADDPHLGLATPSIWLQMHLES
CCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCEEECCCCCCCCCCEEEEEEEECC
GDGLNVSGVIFAGVPGIILGHNEQIAWGVTNTGPDVQQLYIEQRNPDNPHEFLFEDEWEE
CCCCCCCEEEEECCCEEEEECCCEEEEECCCCCCCHHHHHHHCCCCCCHHHCCCCCCCCH
ATVMEEPIKVKDGETVDYEVVETRHGPIVSEFASESGKDTVLSLRWTALDASTELEAIME
HHHHCCCEEECCCCCCEEEEEECCCCCHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHHH
MNRATGWEEFEQGLEKFLVPAQNFVFASNDGTIAYKANGKIPIYEDGQDALLPLNGWEAE
HHHCCCHHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCEEEEECCCCCEEECCCCCCC
SEWQGYIPYDELPTVINPEKGFIATANNQIAPDSYPYHISNVWAQPYRYERIAEVLESGD
CCCCCCCCHHHCCCCCCCCCCEEEECCCCCCCCCCCEEHHHHHCCCHHHHHHHHHHHCCC
NFTAEDMQDLQMDQTDLRAREFVPIFQKVLEDTELTEQEKEALDALSEWDFVADKDAPQP
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LIFEHWMQAIQSTIYQQEIPQVMRELFSTQSQSTENVLRKAASGQKSQWIEDKGGIEVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCCCCCEEEEE
HDALENTMEKLTETYGEDLSAWKWGDYHQVQFHHPLSSVSPLLAFFLNNEDAIPVGGSGV
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCC
TPMATSYDKETGEVDHGASWRFVIDTSDMQSGYHIVGPGQDGHFRSDWYHDQMNDWVEGN
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCC
FHETRLDGAEGEELVLEPGE
CCEEECCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3680178 [H]