Click here to switch to the map view.

The map label for this gene is aroD [H]

Identifier: 23100697

GI number: 23100697

Start: 3380305

End: 3381063

Strand: Reverse

Name: aroD [H]

Synonym: OB3242

Alternate gene names: 23100697

Gene position: 3381063-3380305 (Counterclockwise)

Preceding gene: 23100699

Following gene: 23100695

Centisome position: 93.13

GC content: 35.18

Gene sequence:

>759_bases
ATGACAGCTGATTTATTTACTAATAAGAACATCCCTTACATTTGCACTCCAATCACTGGTAAAAGTAAAGAAGAGATTAT
TACAGAATTACATTCGTTGATCCTTGAAGAACCGGATTTAATTGAATGGCGATTGGACTATTTTGATTCCATTAGCGATA
CAACTGAAGTCTTGTCCACTTTAAAGCAACTAACCTCTGCTAGTTCTATACCATTATTAGTTACGATAAGGTCTGAAAAA
GAAGGTGGCGAGAACATACCACTATCAGAAAAAGAAAAAGTTCAATTGCTCTTAGAAGTTTGTGAGAATTCATCTGTAGA
AATGGTAGATTATGAAGTAGGAAATGACTGTGTTTACGTAAAACAATTAAGAGAAGCATCAAGAAAATATAATAAAAAAT
TGATCCTCTCTTATCATAATTTTGATTATACTCCTAATAGACAAGTTATTTTAAAACGATTATATCAAATGGAGTTTTAT
GGAGCGGATATAGCTAAGGTAGCTGTAATGCCGCAAACAAAAGACGATGTGCTACGCCTTTTAGAATTGACGAAGGAAGC
AAATGAATCAATGGATATACCCGTCGTCACAATGTCTATGGGAGCTCTAGGCAGTTTAAGTAGAATCGTAGGTTGGGCAT
ATGGCTCAATTATCACCTTTGGATTGGGAGTTCAAAGTTCAGCACCTGGACAGGTTCCAATCGCTAATTTAAAACGAATG
ATTCAGATGATGAAAGATACAATCGGTGAATGGAAGTAG

Upstream 100 bases:

>100_bases
TCTAGAATTATATCGAACAATATTCATTTTGCTTAAAAAGAATAACTCTTGTATAATAAGATTCAAATTATTTAGATCGA
TCTAAAAGGAGGGATAAACA

Downstream 100 bases:

>100_bases
TGACAAGATAAAGAAGCAGCAGTTATATATTAAATGAAAATAGCAGTTGAAATCGATACAACCATTATGAAAAAAGGTAG
TAAAATCATACTCTTCTAAT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MTADLFTNKNIPYICTPITGKSKEEIITELHSLILEEPDLIEWRLDYFDSISDTTEVLSTLKQLTSASSIPLLVTIRSEK
EGGENIPLSEKEKVQLLLEVCENSSVEMVDYEVGNDCVYVKQLREASRKYNKKLILSYHNFDYTPNRQVILKRLYQMEFY
GADIAKVAVMPQTKDDVLRLLELTKEANESMDIPVVTMSMGALGSLSRIVGWAYGSIITFGLGVQSSAPGQVPIANLKRM
IQMMKDTIGEWK

Sequences:

>Translated_252_residues
MTADLFTNKNIPYICTPITGKSKEEIITELHSLILEEPDLIEWRLDYFDSISDTTEVLSTLKQLTSASSIPLLVTIRSEK
EGGENIPLSEKEKVQLLLEVCENSSVEMVDYEVGNDCVYVKQLREASRKYNKKLILSYHNFDYTPNRQVILKRLYQMEFY
GADIAKVAVMPQTKDDVLRLLELTKEANESMDIPVVTMSMGALGSLSRIVGWAYGSIITFGLGVQSSAPGQVPIANLKRM
IQMMKDTIGEWK
>Mature_251_residues
TADLFTNKNIPYICTPITGKSKEEIITELHSLILEEPDLIEWRLDYFDSISDTTEVLSTLKQLTSASSIPLLVTIRSEKE
GGENIPLSEKEKVQLLLEVCENSSVEMVDYEVGNDCVYVKQLREASRKYNKKLILSYHNFDYTPNRQVILKRLYQMEFYG
ADIAKVAVMPQTKDDVLRLLELTKEANESMDIPVVTMSMGALGSLSRIVGWAYGSIITFGLGVQSSAPGQVPIANLKRMI
QMMKDTIGEWK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family [H]

Homologues:

Organism=Escherichia coli, GI1787984, Length=243, Percent_Identity=33.3333333333333, Blast_Score=142, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320332, Length=212, Percent_Identity=27.3584905660377, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001381 [H]

Pfam domain/function: PF01487 DHquinase_I [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 28454; Mature: 28323

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADLFTNKNIPYICTPITGKSKEEIITELHSLILEEPDLIEWRLDYFDSISDTTEVLST
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHH
LKQLTSASSIPLLVTIRSEKEGGENIPLSEKEKVQLLLEVCENSSVEMVDYEVGNDCVYV
HHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHH
KQLREASRKYNKKLILSYHNFDYTPNRQVILKRLYQMEFYGADIAKVAVMPQTKDDVLRL
HHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
LELTKEANESMDIPVVTMSMGALGSLSRIVGWAYGSIITFGLGVQSSAPGQVPIANLKRM
HHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
IQMMKDTIGEWK
HHHHHHHHCCCC
>Mature Secondary Structure 
TADLFTNKNIPYICTPITGKSKEEIITELHSLILEEPDLIEWRLDYFDSISDTTEVLST
CCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHH
LKQLTSASSIPLLVTIRSEKEGGENIPLSEKEKVQLLLEVCENSSVEMVDYEVGNDCVYV
HHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHH
KQLREASRKYNKKLILSYHNFDYTPNRQVILKRLYQMEFYGADIAKVAVMPQTKDDVLRL
HHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
LELTKEANESMDIPVVTMSMGALGSLSRIVGWAYGSIITFGLGVQSSAPGQVPIANLKRM
HHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
IQMMKDTIGEWK
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA