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The map label for this gene is walR [H]

Identifier: 23099970

GI number: 23099970

Start: 2571738

End: 2572415

Strand: Reverse

Name: walR [H]

Synonym: OB2515

Alternate gene names: 23099970

Gene position: 2572415-2571738 (Counterclockwise)

Preceding gene: 23099971

Following gene: 23099969

Centisome position: 70.86

GC content: 34.96

Gene sequence:

>678_bases
ATGAAAAAAATATTGATTATAGAGGATGAATATCCGATTAGTCAGGTGATTAAGGTTTATTTAAAAAAAGCAGGATATGA
TGTAGAACAAGTATTTGATGGTTCGAATGCTATGGATACTTTTAAACATGTTGAACCTGATTTGGTTATTCTAGATGTGA
TGCTACCGGGGGTAGACGGTTGGACATTACTACAGGATATACGTAGTAAATGTGCAGTGATCATGCTTACTGCTCTAGGA
GATGTGAATTATCGTTTAGATGGATTAAATCAAGGTGCAGATGACTATATAGCAAAACCTTTTCACGGAGAAGAACTTGT
AGCACGTGTACAGGCAGTTCTTCGACGAATAGGTAATAAAAACAACAACTCGAATGTAATAAAGTTTGGAACATTGGAGA
TTGATGTTGTTGCACACCGTGTTCGCTTATTAGGAACAATCATTGAATTAACTCCAAGAGATTTATCATTATTATTATTT
TTCGCAGATAATCCAAACCGTACGTTTACGAGAGAACAATTACTCGATAGCATTTGGGGTTGGGATTATGATGGTAGTGA
TCGAGCAGTAGATTTATCGATTAAACGGTTACGTAAATCATTAAAAGACTGGCCAAAATCTGAAGGAGAAATAAAAACAT
TTCGTGGATTGGGGTATCAATTCTGTGTTTATAAATAA

Upstream 100 bases:

>100_bases
ATGCTTTTACACTTCTAAGAGGATAATAATTAGACATAATTCTGACATAAAACTGTTGTATACTTTTATTGTATATCAAT
TGGTTACAGGAAGTGGAAAT

Downstream 100 bases:

>100_bases
GTCTAAACGAATTCCTATGCGACGTTACTGGACTAGTCGTTATCTTATAACATTATGTGTTGGTTTATTGATTATAGCAA
TTTTATCTGTATGGTGGATT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKKILIIEDEYPISQVIKVYLKKAGYDVEQVFDGSNAMDTFKHVEPDLVILDVMLPGVDGWTLLQDIRSKCAVIMLTALG
DVNYRLDGLNQGADDYIAKPFHGEELVARVQAVLRRIGNKNNNSNVIKFGTLEIDVVAHRVRLLGTIIELTPRDLSLLLF
FADNPNRTFTREQLLDSIWGWDYDGSDRAVDLSIKRLRKSLKDWPKSEGEIKTFRGLGYQFCVYK

Sequences:

>Translated_225_residues
MKKILIIEDEYPISQVIKVYLKKAGYDVEQVFDGSNAMDTFKHVEPDLVILDVMLPGVDGWTLLQDIRSKCAVIMLTALG
DVNYRLDGLNQGADDYIAKPFHGEELVARVQAVLRRIGNKNNNSNVIKFGTLEIDVVAHRVRLLGTIIELTPRDLSLLLF
FADNPNRTFTREQLLDSIWGWDYDGSDRAVDLSIKRLRKSLKDWPKSEGEIKTFRGLGYQFCVYK
>Mature_225_residues
MKKILIIEDEYPISQVIKVYLKKAGYDVEQVFDGSNAMDTFKHVEPDLVILDVMLPGVDGWTLLQDIRSKCAVIMLTALG
DVNYRLDGLNQGADDYIAKPFHGEELVARVQAVLRRIGNKNNNSNVIKFGTLEIDVVAHRVRLLGTIIELTPRDLSLLLF
FADNPNRTFTREQLLDSIWGWDYDGSDRAVDLSIKRLRKSLKDWPKSEGEIKTFRGLGYQFCVYK

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=38.3259911894273, Blast_Score=160, Evalue=5e-41,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=37.7777777777778, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=35.7466063348416, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=35.8407079646018, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=35.4260089686099, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=32.0175438596491, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=32.0175438596491, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=32.7354260089686, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=35.8649789029536, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=30.2222222222222, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=35.2422907488987, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=32.1428571428571, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=32.4444444444444, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=29.1479820627803, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=31.3559322033898, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=126, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25666; Mature: 25666

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILIIEDEYPISQVIKVYLKKAGYDVEQVFDGSNAMDTFKHVEPDLVILDVMLPGVDG
CCEEEEEECCCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCH
WTLLQDIRSKCAVIMLTALGDVNYRLDGLNQGADDYIAKPFHGEELVARVQAVLRRIGNK
HHHHHHHHHHHHEEEEEHHCCCCEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCC
NNNSNVIKFGTLEIDVVAHRVRLLGTIIELTPRDLSLLLFFADNPNRTFTREQLLDSIWG
CCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHCC
WDYDGSDRAVDLSIKRLRKSLKDWPKSEGEIKTFRGLGYQFCVYK
CCCCCCCCEEHHHHHHHHHHHHHCCCCCCCEEHHHCCCEEEEEEC
>Mature Secondary Structure
MKKILIIEDEYPISQVIKVYLKKAGYDVEQVFDGSNAMDTFKHVEPDLVILDVMLPGVDG
CCEEEEEECCCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCH
WTLLQDIRSKCAVIMLTALGDVNYRLDGLNQGADDYIAKPFHGEELVARVQAVLRRIGNK
HHHHHHHHHHHHEEEEEHHCCCCEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCC
NNNSNVIKFGTLEIDVVAHRVRLLGTIIELTPRDLSLLLFFADNPNRTFTREQLLDSIWG
CCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHCC
WDYDGSDRAVDLSIKRLRKSLKDWPKSEGEIKTFRGLGYQFCVYK
CCCCCCCCEEHHHHHHHHHHHHHCCCCCCCEEHHHCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA