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The map label for this gene is cotH [H]

Identifier: 23099966

GI number: 23099966

Start: 2566903

End: 2568492

Strand: Reverse

Name: cotH [H]

Synonym: OB2511

Alternate gene names: 23099966

Gene position: 2568492-2566903 (Counterclockwise)

Preceding gene: 23099967

Following gene: 23099965

Centisome position: 70.75

GC content: 36.48

Gene sequence:

>1590_bases
TTGAGGGTAACCAATCGACGGAAGAAAATGTTTATTTTGCTTACAATCACGTTAATGACGATGTTTAGTTATCGAATCAA
TCCTGCATCTGCAGCTGATCAAAATACTGATAAGATCTTTCAACAAGATGAAATAAGTGAAGTGAATATAGAGTTAGATG
AGCAGGATTTTCAGAGTATGCTAGATAATCCGATGGAAGAAGAATACCAGGTAGCATCAGTTACGTACAATGGACAAACA
ATTGAAAACACTGGAGTTCGCGTGAAAGGAAATTCATCACTTCGTAGTGTTGCTAGTTCTGAATCAGATCGATATAGTTT
TAAGCTGAAATTTGATGAATATATAGATCAAGATTTAGAAGGATATACGAAAATCAATTTAAATAATAATTTTGCCGATC
CATCATATATGCGTGAATACTTAACATATGAGTTGATGGAAAAAATGGGTCTACCTACTCCGAATTATAGCTATGTCAAT
GTATATGTCAATGGTGAACATTATGGGTTTTATTTAGCTGTTGAAAATATTGAAGAAAACTATTTAGATCGTAATTTTAA
TGATACATCAGGAAATCTATATAAAGCTGATTCAGGTGCATCCCTTATTTGGGAAGAAGGAATGGAAGTAGAGGATACCT
CACTTAATTTAAAAATCGGACTAGAAGGGAATACTTCGTTGTTATCCTTCATTGAGGGACTTAATACTGGTGAGAAGGTA
GAGGATTATTTTGATGTTGACACATATTTAAGATATTTAGCAGTGAGTACTGTAGTTGCTAATATGGATAGCTATCAGGG
GATGATGAGTCATAATTATTATTTATATGAGCAGGATGGTAAATTCACGTTTTTACCATGGGATCATAATATGTCATTTG
CAGGCATGATGGGATCAGACCCATCGGAACTATTGATAGATGAACCAACCGCCGGAGCAGTGGAGAATTTTCCTCTTGTC
GATTATGTACTCTCTAATGATGATTACAAACAAATATATCATCAATATGTGCAAGAGACGGTTGATTTACTAGATAATTT
TGAGGAGAGAGTGAATTCACTAGAGAATTTAATCGGTACTGCTGTGGAGAATGATCCAACTGCATTTTATAGCTATGAAG
AATTTACAGCAAATATTGGAGATCAAGAGGTTGATGGCTATCCAGGATTGGTTGGATTTATAACAAATCGATTAGAACAC
GTACAACAACAATTGGATGGTGAAATTGCAAGTTATAATAATGGAGAAGGTTTGCAATCCAACATGCCGGCTGGTGGTAT
GCCTGATGATGCAGCAGGAGCTATGCCGCAAATGAATGGTGACTTAGAAGACGGTGTGGGTGGTATGCAACGGAACGGAG
AGCAAATGCAAGAAGGTGGTATGCCGGAGGTAAATGGCGAAGAAATGCCAGATATGCAAGAAGGAGGCATGCCAGGGATG
CGGCAAGAAGGAATGCCTGGTAGAATGCAAGGTACAAATCAAGATGCAACCGAAAATCAAAAGTTTGAATTTTGGGTGGT
TGTGATTAGTGTTATTGTATTAATCTGTAGCATTCTCTTTGTTAATTTATTTAAAAGGTATCATCGATGA

Upstream 100 bases:

>100_bases
TTTGTAAATTCAATTTCTGACATACAAGGAGTTGGAAATGCTGTACTAATTAGTTATAACGGGGATTATGTTCAATAAGG
CAAAAAAGAAGGTGAATATT

Downstream 100 bases:

>100_bases
AGTAAATGAATCGTAATTAGGAAAAACAAGTTTGAGACATAACGTATGTTCAAAAGATGTAATGTAATCAGAAATGGTGA
AAACCAATCTGTTTTAAATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MRVTNRRKKMFILLTITLMTMFSYRINPASAADQNTDKIFQQDEISEVNIELDEQDFQSMLDNPMEEEYQVASVTYNGQT
IENTGVRVKGNSSLRSVASSESDRYSFKLKFDEYIDQDLEGYTKINLNNNFADPSYMREYLTYELMEKMGLPTPNYSYVN
VYVNGEHYGFYLAVENIEENYLDRNFNDTSGNLYKADSGASLIWEEGMEVEDTSLNLKIGLEGNTSLLSFIEGLNTGEKV
EDYFDVDTYLRYLAVSTVVANMDSYQGMMSHNYYLYEQDGKFTFLPWDHNMSFAGMMGSDPSELLIDEPTAGAVENFPLV
DYVLSNDDYKQIYHQYVQETVDLLDNFEERVNSLENLIGTAVENDPTAFYSYEEFTANIGDQEVDGYPGLVGFITNRLEH
VQQQLDGEIASYNNGEGLQSNMPAGGMPDDAAGAMPQMNGDLEDGVGGMQRNGEQMQEGGMPEVNGEEMPDMQEGGMPGM
RQEGMPGRMQGTNQDATENQKFEFWVVVISVIVLICSILFVNLFKRYHR

Sequences:

>Translated_529_residues
MRVTNRRKKMFILLTITLMTMFSYRINPASAADQNTDKIFQQDEISEVNIELDEQDFQSMLDNPMEEEYQVASVTYNGQT
IENTGVRVKGNSSLRSVASSESDRYSFKLKFDEYIDQDLEGYTKINLNNNFADPSYMREYLTYELMEKMGLPTPNYSYVN
VYVNGEHYGFYLAVENIEENYLDRNFNDTSGNLYKADSGASLIWEEGMEVEDTSLNLKIGLEGNTSLLSFIEGLNTGEKV
EDYFDVDTYLRYLAVSTVVANMDSYQGMMSHNYYLYEQDGKFTFLPWDHNMSFAGMMGSDPSELLIDEPTAGAVENFPLV
DYVLSNDDYKQIYHQYVQETVDLLDNFEERVNSLENLIGTAVENDPTAFYSYEEFTANIGDQEVDGYPGLVGFITNRLEH
VQQQLDGEIASYNNGEGLQSNMPAGGMPDDAAGAMPQMNGDLEDGVGGMQRNGEQMQEGGMPEVNGEEMPDMQEGGMPGM
RQEGMPGRMQGTNQDATENQKFEFWVVVISVIVLICSILFVNLFKRYHR
>Mature_529_residues
MRVTNRRKKMFILLTITLMTMFSYRINPASAADQNTDKIFQQDEISEVNIELDEQDFQSMLDNPMEEEYQVASVTYNGQT
IENTGVRVKGNSSLRSVASSESDRYSFKLKFDEYIDQDLEGYTKINLNNNFADPSYMREYLTYELMEKMGLPTPNYSYVN
VYVNGEHYGFYLAVENIEENYLDRNFNDTSGNLYKADSGASLIWEEGMEVEDTSLNLKIGLEGNTSLLSFIEGLNTGEKV
EDYFDVDTYLRYLAVSTVVANMDSYQGMMSHNYYLYEQDGKFTFLPWDHNMSFAGMMGSDPSELLIDEPTAGAVENFPLV
DYVLSNDDYKQIYHQYVQETVDLLDNFEERVNSLENLIGTAVENDPTAFYSYEEFTANIGDQEVDGYPGLVGFITNRLEH
VQQQLDGEIASYNNGEGLQSNMPAGGMPDDAAGAMPQMNGDLEDGVGGMQRNGEQMQEGGMPEVNGEEMPDMQEGGMPGM
RQEGMPGRMQGTNQDATENQKFEFWVVVISVIVLICSILFVNLFKRYHR

Specific function: Involved in the assembly of several proteins in the inner and outer layer of the spore coat. Stabilizes CotC and CotU in the mother cell compartment of sporulating cells and promotes the assembly of both early and late forms of CotC-related polypeptides o

COG id: COG5337

COG function: function code M; Spore coat assembly protein

Gene ontology:

Cell location: Spore wall, spore coat [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CotH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014867 [H]

Pfam domain/function: PF08757 CotH [H]

EC number: NA

Molecular weight: Translated: 60037; Mature: 60037

Theoretical pI: Translated: 3.89; Mature: 3.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVTNRRKKMFILLTITLMTMFSYRINPASAADQNTDKIFQQDEISEVNIELDEQDFQSM
CCCCCCCHHEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCEEEEEECHHHHHHH
LDNPMEEEYQVASVTYNGQTIENTGVRVKGNSSLRSVASSESDRYSFKLKFDEYIDQDLE
HCCCCCCCEEEEEEEECCEEEECCCEEEECCHHHHHHHCCCCCCEEEEEEEHHHHCHHCC
GYTKINLNNNFADPSYMREYLTYELMEKMGLPTPNYSYVNVYVNGEHYGFYLAVENIEEN
CEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEEEEECCHHH
YLDRNFNDTSGNLYKADSGASLIWEEGMEVEDTSLNLKIGLEGNTSLLSFIEGLNTGEKV
HHCCCCCCCCCCEEECCCCCEEHHHCCCCEECCEEEEEEECCCCHHHHHHHHCCCCCCHH
EDYFDVDTYLRYLAVSTVVANMDSYQGMMSHNYYLYEQDGKFTFLPWDHNMSFAGMMGSD
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCEEECCCCC
PSELLIDEPTAGAVENFPLVDYVLSNDDYKQIYHQYVQETVDLLDNFEERVNSLENLIGT
CCCEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVENDPTAFYSYEEFTANIGDQEVDGYPGLVGFITNRLEHVQQQLDGEIASYNNGEGLQS
HCCCCCCEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NMPAGGMPDDAAGAMPQMNGDLEDGVGGMQRNGEQMQEGGMPEVNGEEMPDMQEGGMPGM
CCCCCCCCCCCCCCCCCCCCCHHHCCCCHHCCCHHHHHCCCCCCCCCCCCCHHHCCCCCC
RQEGMPGRMQGTNQDATENQKFEFWVVVISVIVLICSILFVNLFKRYHR
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVTNRRKKMFILLTITLMTMFSYRINPASAADQNTDKIFQQDEISEVNIELDEQDFQSM
CCCCCCCHHEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCEEEEEECHHHHHHH
LDNPMEEEYQVASVTYNGQTIENTGVRVKGNSSLRSVASSESDRYSFKLKFDEYIDQDLE
HCCCCCCCEEEEEEEECCEEEECCCEEEECCHHHHHHHCCCCCCEEEEEEEHHHHCHHCC
GYTKINLNNNFADPSYMREYLTYELMEKMGLPTPNYSYVNVYVNGEHYGFYLAVENIEEN
CEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEEEEECCHHH
YLDRNFNDTSGNLYKADSGASLIWEEGMEVEDTSLNLKIGLEGNTSLLSFIEGLNTGEKV
HHCCCCCCCCCCEEECCCCCEEHHHCCCCEECCEEEEEEECCCCHHHHHHHHCCCCCCHH
EDYFDVDTYLRYLAVSTVVANMDSYQGMMSHNYYLYEQDGKFTFLPWDHNMSFAGMMGSD
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCEEECCCCC
PSELLIDEPTAGAVENFPLVDYVLSNDDYKQIYHQYVQETVDLLDNFEERVNSLENLIGT
CCCEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVENDPTAFYSYEEFTANIGDQEVDGYPGLVGFITNRLEHVQQQLDGEIASYNNGEGLQS
HCCCCCCEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NMPAGGMPDDAAGAMPQMNGDLEDGVGGMQRNGEQMQEGGMPEVNGEEMPDMQEGGMPGM
CCCCCCCCCCCCCCCCCCCCCHHHCCCCHHCCCHHHHHCCCCCCCCCCCCCHHHCCCCCC
RQEGMPGRMQGTNQDATENQKFEFWVVVISVIVLICSILFVNLFKRYHR
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8755863; 8991897; 9353933; 9384377; 7814326; 10198031 [H]