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The map label for this gene is hbpA [H]

Identifier: 23099906

GI number: 23099906

Start: 2507880

End: 2509541

Strand: Reverse

Name: hbpA [H]

Synonym: OB2451

Alternate gene names: 23099906

Gene position: 2509541-2507880 (Counterclockwise)

Preceding gene: 23099907

Following gene: 23099905

Centisome position: 69.12

GC content: 38.27

Gene sequence:

>1662_bases
ATGAAAAAGAAATATCTGATTTTGTTAATGCTTGCATTTGTATTATTGATAATGGCTGCATGTTCCGGCGATGGTGGAGC
AAATCCGGAAGATGCTAATGATGATGCAGGAACAGAAGATAATGGTTCTGATGCTTCCGCTTCTGAGGATCAAGTACTTG
TTTTTGCACGAGGTGGAGATTCTGAAAGTTTAGATCCTGGGAGTACCACTGATGGAGAATCCTCAAGAGTAACTAGACAA
ATTCTCGAAAGTTTACTAGATTTTGATAAAGAATCGTTCGAAATAAAACCAGGTTTAGCACATGATTGGGATATATCAGA
AGATGGTCTTACGTACACTTTCTATTTAGAAGAAGGGGTTACTTTCCATGATGGGACAGATTTTAATGCTGAAGCTGTAA
AAACGAATTTTGAACGCTGGGCAGATCCAAATCATGAGTATGCCTTTACGGATGAAGGATTTGTTTACAATATTTACGGT
ACGATGTTTGGCGGTTTTGAAGGTGATGAAGGACATGTTATAGACGAAATCAATGCGGTTAGTGAACATGAAGTGGAATT
CGTATTAAAAGAACCACTAGGATTCTTTTTACAGAATCTAGCGATGTCTTATTTTGCAATAACTTCTCCTGCTGCCTTAG
AGGAATATGGTCCAGATATTACTGAAAACCCAGTGGGTACAGGGCCGTTTAAATTTAATAATTGGAGTAAGAATGACTCC
ATTGTATTAGATAAGTTTGAAGATTATCGAGTTGAAGGGCTTCCTAAACTAGATCAGGTTATTTTCCAAGTAATACCGGA
TAATTCAGCACGACTAATTGCTTTGCAATCAGGTGAAATTGATATGATGGATGGTTTAAATCCGGATGATGCTGCTGGTC
TCGAAGGGGAAGAAGGAATTGAATTATTAACTCGTGGTGAGAATAACTTTGGATATGTAGGATTCCATACCCAAAAAGAA
CCAGTTGATCAAAAAGAAGTGAGACAGGCAATTAATTATGCAATTAATAAACAAGCAATCGCTGATGCATTATATGCGGG
TTATGCAACTACTGCAAAGAACCCACTGCCACCAAGCTATCTAGGATATAACGATGGAGTAGAGGGATATGAATATAATC
CTGATCGAGCGAGAGAATTGTTAGAGGAAGCAGGACACGCAGACGGTCTTGAAATTGAATTAATGATTTCTCCAACCGCT
CGACCTTACATGCCAGATCCGGAAACAGTTGCTCAAATTGTACAAGAAAACCTATCTGAAGTTGGTATTGAGTTAACAAT
TACGTCACATGAATGGGCTCCATACCTCGAGTTAACAGAACAAGGAGAACACCAAATGTACATTTTAGGATGGTCTGGTA
CAAATGGTGATCCGGATTATTTCCTAAGTAGTTTATTGCATAGCTCTAACATTGGAAGTAGTAACAATACGTTCTATGAA
AACTCTGAAGTAGATGATTTATTAAATCAGGCTAAACGTGCGGTTGATCAAGATGAACGTGCAGATTTATATATGCAGGC
TCAAGAATTAATATCTGAAGATTCACCAATGGTGACACTTGTGCACTCGACGCCGGTAATGGCTATCTCGTCAAATGTAC
AAAATTATGTTCCACACCCATCTACAAGTGAATCCTTAGCAGAAGTACAATTAGGAGAATAA

Upstream 100 bases:

>100_bases
TACCGCAGTTTTTACCAGTTGAGGATAATCATGTTGTTGCTTGTCATTTATATAGTGATGAACAGCAATATTTATCAAAA
CAAAAAGAGGGGGAACTAGT

Downstream 100 bases:

>100_bases
AGGTAAGAGGTTGGGATAAAAGTATAGCAATTGATAAATTCGAATGGGTGACTTTGTACACCCGTTCAGAAATACAATGT
GCTTATCTAACGGCGGATGG

Product: dipeptide ABC transporter dipeptide-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MKKKYLILLMLAFVLLIMAACSGDGGANPEDANDDAGTEDNGSDASASEDQVLVFARGGDSESLDPGSTTDGESSRVTRQ
ILESLLDFDKESFEIKPGLAHDWDISEDGLTYTFYLEEGVTFHDGTDFNAEAVKTNFERWADPNHEYAFTDEGFVYNIYG
TMFGGFEGDEGHVIDEINAVSEHEVEFVLKEPLGFFLQNLAMSYFAITSPAALEEYGPDITENPVGTGPFKFNNWSKNDS
IVLDKFEDYRVEGLPKLDQVIFQVIPDNSARLIALQSGEIDMMDGLNPDDAAGLEGEEGIELLTRGENNFGYVGFHTQKE
PVDQKEVRQAINYAINKQAIADALYAGYATTAKNPLPPSYLGYNDGVEGYEYNPDRARELLEEAGHADGLEIELMISPTA
RPYMPDPETVAQIVQENLSEVGIELTITSHEWAPYLELTEQGEHQMYILGWSGTNGDPDYFLSSLLHSSNIGSSNNTFYE
NSEVDDLLNQAKRAVDQDERADLYMQAQELISEDSPMVTLVHSTPVMAISSNVQNYVPHPSTSESLAEVQLGE

Sequences:

>Translated_553_residues
MKKKYLILLMLAFVLLIMAACSGDGGANPEDANDDAGTEDNGSDASASEDQVLVFARGGDSESLDPGSTTDGESSRVTRQ
ILESLLDFDKESFEIKPGLAHDWDISEDGLTYTFYLEEGVTFHDGTDFNAEAVKTNFERWADPNHEYAFTDEGFVYNIYG
TMFGGFEGDEGHVIDEINAVSEHEVEFVLKEPLGFFLQNLAMSYFAITSPAALEEYGPDITENPVGTGPFKFNNWSKNDS
IVLDKFEDYRVEGLPKLDQVIFQVIPDNSARLIALQSGEIDMMDGLNPDDAAGLEGEEGIELLTRGENNFGYVGFHTQKE
PVDQKEVRQAINYAINKQAIADALYAGYATTAKNPLPPSYLGYNDGVEGYEYNPDRARELLEEAGHADGLEIELMISPTA
RPYMPDPETVAQIVQENLSEVGIELTITSHEWAPYLELTEQGEHQMYILGWSGTNGDPDYFLSSLLHSSNIGSSNNTFYE
NSEVDDLLNQAKRAVDQDERADLYMQAQELISEDSPMVTLVHSTPVMAISSNVQNYVPHPSTSESLAEVQLGE
>Mature_553_residues
MKKKYLILLMLAFVLLIMAACSGDGGANPEDANDDAGTEDNGSDASASEDQVLVFARGGDSESLDPGSTTDGESSRVTRQ
ILESLLDFDKESFEIKPGLAHDWDISEDGLTYTFYLEEGVTFHDGTDFNAEAVKTNFERWADPNHEYAFTDEGFVYNIYG
TMFGGFEGDEGHVIDEINAVSEHEVEFVLKEPLGFFLQNLAMSYFAITSPAALEEYGPDITENPVGTGPFKFNNWSKNDS
IVLDKFEDYRVEGLPKLDQVIFQVIPDNSARLIALQSGEIDMMDGLNPDDAAGLEGEEGIELLTRGENNFGYVGFHTQKE
PVDQKEVRQAINYAINKQAIADALYAGYATTAKNPLPPSYLGYNDGVEGYEYNPDRARELLEEAGHADGLEIELMISPTA
RPYMPDPETVAQIVQENLSEVGIELTITSHEWAPYLELTEQGEHQMYILGWSGTNGDPDYFLSSLLHSSNIGSSNNTFYE
NSEVDDLLNQAKRAVDQDERADLYMQAQELISEDSPMVTLVHSTPVMAISSNVQNYVPHPSTSESLAEVQLGE

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=510, Percent_Identity=34.5098039215686, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1787052, Length=518, Percent_Identity=35.7142857142857, Blast_Score=291, Evalue=5e-80,
Organism=Escherichia coli, GI1787762, Length=510, Percent_Identity=27.2549019607843, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1787551, Length=556, Percent_Identity=26.6187050359712, Blast_Score=191, Evalue=8e-50,
Organism=Escherichia coli, GI1787495, Length=510, Percent_Identity=26.2745098039216, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1789397, Length=512, Percent_Identity=23.4375, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1789887, Length=451, Percent_Identity=25.7206208425721, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87081878, Length=490, Percent_Identity=24.4897959183673, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61073; Mature: 61073

Theoretical pI: Translated: 3.84; Mature: 3.84

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKYLILLMLAFVLLIMAACSGDGGANPEDANDDAGTEDNGSDASASEDQVLVFARGGD
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
SESLDPGSTTDGESSRVTRQILESLLDFDKESFEIKPGLAHDWDISEDGLTYTFYLEEGV
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEEEEEECCC
TFHDGTDFNAEAVKTNFERWADPNHEYAFTDEGFVYNIYGTMFGGFEGDEGHVIDEINAV
EEECCCCCCHHHHHHHHHHHCCCCCCEEECCCCEEEEEEEHHCCCCCCCCCCEEHHHHCC
SEHEVEFVLKEPLGFFLQNLAMSYFAITSPAALEEYGPDITENPVGTGPFKFNNWSKNDS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCEECCCCCCCCC
IVLDKFEDYRVEGLPKLDQVIFQVIPDNSARLIALQSGEIDMMDGLNPDDAAGLEGEEGI
EEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCEEECCCCCCCCCCCCCCCCCC
ELLTRGENNFGYVGFHTQKEPVDQKEVRQAINYAINKQAIADALYAGYATTAKNPLPPSY
HHEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCC
LGYNDGVEGYEYNPDRARELLEEAGHADGLEIELMISPTARPYMPDPETVAQIVQENLSE
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
VGIELTITSHEWAPYLELTEQGEHQMYILGWSGTNGDPDYFLSSLLHSSNIGSSNNTFYE
CCEEEEEECCCCCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEC
NSEVDDLLNQAKRAVDQDERADLYMQAQELISEDSPMVTLVHSTPVMAISSNVQNYVPHP
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCHHHCCCCC
STSESLAEVQLGE
CCCHHHHHEECCC
>Mature Secondary Structure
MKKKYLILLMLAFVLLIMAACSGDGGANPEDANDDAGTEDNGSDASASEDQVLVFARGGD
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
SESLDPGSTTDGESSRVTRQILESLLDFDKESFEIKPGLAHDWDISEDGLTYTFYLEEGV
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEEEEEECCC
TFHDGTDFNAEAVKTNFERWADPNHEYAFTDEGFVYNIYGTMFGGFEGDEGHVIDEINAV
EEECCCCCCHHHHHHHHHHHCCCCCCEEECCCCEEEEEEEHHCCCCCCCCCCEEHHHHCC
SEHEVEFVLKEPLGFFLQNLAMSYFAITSPAALEEYGPDITENPVGTGPFKFNNWSKNDS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCEECCCCCCCCC
IVLDKFEDYRVEGLPKLDQVIFQVIPDNSARLIALQSGEIDMMDGLNPDDAAGLEGEEGI
EEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCEEECCCCCCCCCCCCCCCCCC
ELLTRGENNFGYVGFHTQKEPVDQKEVRQAINYAINKQAIADALYAGYATTAKNPLPPSY
HHEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCC
LGYNDGVEGYEYNPDRARELLEEAGHADGLEIELMISPTARPYMPDPETVAQIVQENLSE
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
VGIELTITSHEWAPYLELTEQGEHQMYILGWSGTNGDPDYFLSSLLHSSNIGSSNNTFYE
CCEEEEEECCCCCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEC
NSEVDDLLNQAKRAVDQDERADLYMQAQELISEDSPMVTLVHSTPVMAISSNVQNYVPHP
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCHHHCCCCC
STSESLAEVQLGE
CCCHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]