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The map label for this gene is dppB [H]

Identifier: 23099905

GI number: 23099905

Start: 2506388

End: 2507389

Strand: Reverse

Name: dppB [H]

Synonym: OB2450

Alternate gene names: 23099905

Gene position: 2507389-2506388 (Counterclockwise)

Preceding gene: 23099906

Following gene: 23099904

Centisome position: 69.06

GC content: 34.83

Gene sequence:

>1002_bases
ATGCTAGCTTACATAGGTCGTAGATTATTAATGCTCATACCAGTTCTACTCGGAATGACGATTATAACATTTTCCATTGT
ACATTTAATTCCTGGTAATCCAGCTAAGGTTATACTAGGAGAAACAGCCACGGAACAATCCATAAAAAGCCTTGAAGAAT
CCATGGGGTTAAATGAACCGTATCTTGTACAATATTCTCGCTATCTCGGTGATTTGGTACAAGGCGATTTGGGGACTTCG
TTACGAACAAAGGCAGATATTTCAAGTGAAATTTGGCCTTATATAGCTGCTACATTCGAATTGACACTTTTTGCAATGCT
TTTTGCTATTGTAATTGGTGTAAATGCAGGAATTATTAGTGCTTGGAAGCAAAACTCCTGGTTTGATTTTCTTGCTATGT
TGTTTGCTTTAATTGGGGTGTCAATGCCTGTATTCTGGCTTGCGCTTATGGAGCAATGGGTATTTGCACAAGAACTCGGA
TGGTTGCCTGCAAATAGTAGACAGAACCCAAGGGATCCAATAGCTGTAATTACTCACTTCTATGTTCTTGATTCTCTAAT
TCATCTTGATTTTGAACGAACATTAACTATCTTAAAACATTTAGTATTACCTAGTATTGCATTAGGAACTATACCAATGG
CGATTATTGCTCGTATGACAAGATCAAGTATGTTAGAGGTAATGAAATCAGACTACATTAGAACAGTGCGTGCAAAAGGA
TCAGGTCAATTTTTAGTCATTTATAAGCATGCATTAAAAAATGCAATTATACCTGTTATTACTGTTATTGGACTACAAAC
TGGAGTGCTATTAGGTGGAGCAATATTAACAGAAACAATATTTAGTTGGCCAGGTATAGGAAGGTATGTATATGAAGCAA
TTAGTTTCCGAGATTATCCTGTAATTCAATCTGGAATTTTAGTGATTGCATTTTTATTTGTCATTATTAATCTAATTGTA
GATATTTTGTACAAGAAAATTGATCCAAGGATTAATTATTAA

Upstream 100 bases:

>100_bases
ATAATCATCGTTTGTGTGTGCAAATAACCCATACTTTTTGATTATCTATGGACCTTTAACACATAGAATAAAGTGAAAAC
CATTAGTCTGAGGTGATGAT

Downstream 100 bases:

>100_bases
GGGGGATGGAAAATAATGAAGAGCAAACATTCACATGCAGAACAGCAAACTGCTGATCCATCTCTTGTAAGTCAATTACA
ACAAGATCATATAGAAGAAA

Product: dipeptide ABC transporter permease

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MLAYIGRRLLMLIPVLLGMTIITFSIVHLIPGNPAKVILGETATEQSIKSLEESMGLNEPYLVQYSRYLGDLVQGDLGTS
LRTKADISSEIWPYIAATFELTLFAMLFAIVIGVNAGIISAWKQNSWFDFLAMLFALIGVSMPVFWLALMEQWVFAQELG
WLPANSRQNPRDPIAVITHFYVLDSLIHLDFERTLTILKHLVLPSIALGTIPMAIIARMTRSSMLEVMKSDYIRTVRAKG
SGQFLVIYKHALKNAIIPVITVIGLQTGVLLGGAILTETIFSWPGIGRYVYEAISFRDYPVIQSGILVIAFLFVIINLIV
DILYKKIDPRINY

Sequences:

>Translated_333_residues
MLAYIGRRLLMLIPVLLGMTIITFSIVHLIPGNPAKVILGETATEQSIKSLEESMGLNEPYLVQYSRYLGDLVQGDLGTS
LRTKADISSEIWPYIAATFELTLFAMLFAIVIGVNAGIISAWKQNSWFDFLAMLFALIGVSMPVFWLALMEQWVFAQELG
WLPANSRQNPRDPIAVITHFYVLDSLIHLDFERTLTILKHLVLPSIALGTIPMAIIARMTRSSMLEVMKSDYIRTVRAKG
SGQFLVIYKHALKNAIIPVITVIGLQTGVLLGGAILTETIFSWPGIGRYVYEAISFRDYPVIQSGILVIAFLFVIINLIV
DILYKKIDPRINY
>Mature_333_residues
MLAYIGRRLLMLIPVLLGMTIITFSIVHLIPGNPAKVILGETATEQSIKSLEESMGLNEPYLVQYSRYLGDLVQGDLGTS
LRTKADISSEIWPYIAATFELTLFAMLFAIVIGVNAGIISAWKQNSWFDFLAMLFALIGVSMPVFWLALMEQWVFAQELG
WLPANSRQNPRDPIAVITHFYVLDSLIHLDFERTLTILKHLVLPSIALGTIPMAIIARMTRSSMLEVMKSDYIRTVRAKG
SGQFLVIYKHALKNAIIPVITVIGLQTGVLLGGAILTETIFSWPGIGRYVYEAISFRDYPVIQSGILVIAFLFVIINLIV
DILYKKIDPRINY

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=44.3786982248521, Blast_Score=290, Evalue=8e-80,
Organism=Escherichia coli, GI1787053, Length=333, Percent_Identity=39.9399399399399, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI1787761, Length=327, Percent_Identity=42.5076452599388, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1789888, Length=335, Percent_Identity=33.7313432835821, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1787497, Length=338, Percent_Identity=34.9112426035503, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1787550, Length=265, Percent_Identity=33.9622641509434, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1788504, Length=378, Percent_Identity=24.8677248677249, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37269; Mature: 37269

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAYIGRRLLMLIPVLLGMTIITFSIVHLIPGNPAKVILGETATEQSIKSLEESMGLNEP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCC
YLVQYSRYLGDLVQGDLGTSLRTKADISSEIWPYIAATFELTLFAMLFAIVIGVNAGIIS
HHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AWKQNSWFDFLAMLFALIGVSMPVFWLALMEQWVFAQELGWLPANSRQNPRDPIAVITHF
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
YVLDSLIHLDFERTLTILKHLVLPSIALGTIPMAIIARMTRSSMLEVMKSDYIRTVRAKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SGQFLVIYKHALKNAIIPVITVIGLQTGVLLGGAILTETIFSWPGIGRYVYEAISFRDYP
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCH
VIQSGILVIAFLFVIINLIVDILYKKIDPRINY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLAYIGRRLLMLIPVLLGMTIITFSIVHLIPGNPAKVILGETATEQSIKSLEESMGLNEP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCC
YLVQYSRYLGDLVQGDLGTSLRTKADISSEIWPYIAATFELTLFAMLFAIVIGVNAGIIS
HHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AWKQNSWFDFLAMLFALIGVSMPVFWLALMEQWVFAQELGWLPANSRQNPRDPIAVITHF
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
YVLDSLIHLDFERTLTILKHLVLPSIALGTIPMAIIARMTRSSMLEVMKSDYIRTVRAKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SGQFLVIYKHALKNAIIPVITVIGLQTGVLLGGAILTETIFSWPGIGRYVYEAISFRDYP
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCH
VIQSGILVIAFLFVIINLIVDILYKKIDPRINY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9680333 [H]