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The map label for this gene is ccpA [H]

Identifier: 23099681

GI number: 23099681

Start: 2264345

End: 2265343

Strand: Reverse

Name: ccpA [H]

Synonym: OB2226

Alternate gene names: 23099681

Gene position: 2265343-2264345 (Counterclockwise)

Preceding gene: 23099682

Following gene: 23099680

Centisome position: 62.4

GC content: 35.14

Gene sequence:

>999_bases
ATGAATGTGACTATTTACGATGTAGCAAGAGAAGCAAATGTCTCCATGGCTACGGTTTCTCGTGTGGTTAACGGAAACCC
GAATGTGAAACCAACAACAAGAAAGAAAGTATTAGCAACAATTGAACAACTTGGATATCGTCCCAATGCTGTAGCAAGAG
GGCTTGCAAGTAAAAAGACAACAACTGTTGGAGCGATTATTCCTGATATCTCCAATATATTCTTTTCAGAACTAGCGCGT
GGGATTGAAGATATTGCTACCATGTATAAATATAATATAATTTTGAGTAGTTCGGATCAAAACAAGGATAAGGAATTAGA
ATTAATTAATACCATGCTGGAAAAGCAGGTTGATGGAATACTGTTTATGGGTGGTAATATTTCAGAAGAACATATTCACC
AATTTCAAACTTCGTCAGTTCCTGTCGTATTAGCTTCCACATATGATCCAACAGATACTATTCCTTCAGTGAATATTGAT
TATGAACTTGCTGCATATGAAGCAACAAAGCAATTAATACAAAAAGGAAATAAGCAGCCTGCATTAGTTGGAAGTAAAGC
AGACACTAGTGTAAACAACTTGAAAACCAGTGGTTATCTAAGAGCGTTAAAAGAAGCAAATATAGAAGTAAATGAAGATT
ATATATATAAAGATGAGTATGCTTATCAAACTGGAATTGAAGCAGTAGAATATCTTATAGGTTTAGATGACCAGCCTAAT
GCTGTGTTTGTTATGTACGATGAAATAGCATTAGGAGTTATCCATGGAGCTCAGGATAAAGGACTTGATGTGCCTAATGA
CTTAGAAGTATTTGGCTTTGATAACATTCGCTTATCAACAATGGTTCGACCTACATTGACAACTATCGTACAACCAACAT
ATGATATAGGCGCAGTAGGGATGCGATTGTTAACGAAATATATGAACAAAGAGCAAGTCGATGAAAAAAATGTTGTTTTA
CCTCATCGAATTGAGTTTAGAAACTCAACAATTCAATAA

Upstream 100 bases:

>100_bases
CAGTTTAGAAAGTATAAATATTCTTTACTACATGATCGCAAATGAAGCTTGCACCACTAGATTTTGGTGATGAGTGAGTG
TCTAATAGGAGGTATATATA

Downstream 100 bases:

>100_bases
TAATACCGATAAAAGGTATAGATGAATAGAAGTTCAAAAGGTTATCTTATAGGTAACATTTTGAACTTCTCTTATGTCAG
AAAAGCTATGGGAGAATGAT

Product: transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLATIEQLGYRPNAVARGLASKKTTTVGAIIPDISNIFFSELAR
GIEDIATMYKYNIILSSSDQNKDKELELINTMLEKQVDGILFMGGNISEEHIHQFQTSSVPVVLASTYDPTDTIPSVNID
YELAAYEATKQLIQKGNKQPALVGSKADTSVNNLKTSGYLRALKEANIEVNEDYIYKDEYAYQTGIEAVEYLIGLDDQPN
AVFVMYDEIALGVIHGAQDKGLDVPNDLEVFGFDNIRLSTMVRPTLTTIVQPTYDIGAVGMRLLTKYMNKEQVDEKNVVL
PHRIEFRNSTIQ

Sequences:

>Translated_332_residues
MNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLATIEQLGYRPNAVARGLASKKTTTVGAIIPDISNIFFSELAR
GIEDIATMYKYNIILSSSDQNKDKELELINTMLEKQVDGILFMGGNISEEHIHQFQTSSVPVVLASTYDPTDTIPSVNID
YELAAYEATKQLIQKGNKQPALVGSKADTSVNNLKTSGYLRALKEANIEVNEDYIYKDEYAYQTGIEAVEYLIGLDDQPN
AVFVMYDEIALGVIHGAQDKGLDVPNDLEVFGFDNIRLSTMVRPTLTTIVQPTYDIGAVGMRLLTKYMNKEQVDEKNVVL
PHRIEFRNSTIQ
>Mature_332_residues
MNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLATIEQLGYRPNAVARGLASKKTTTVGAIIPDISNIFFSELAR
GIEDIATMYKYNIILSSSDQNKDKELELINTMLEKQVDGILFMGGNISEEHIHQFQTSSVPVVLASTYDPTDTIPSVNID
YELAAYEATKQLIQKGNKQPALVGSKADTSVNNLKTSGYLRALKEANIEVNEDYIYKDEYAYQTGIEAVEYLIGLDDQPN
AVFVMYDEIALGVIHGAQDKGLDVPNDLEVFGFDNIRLSTMVRPTLTTIVQPTYDIGAVGMRLLTKYMNKEQVDEKNVVL
PHRIEFRNSTIQ

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=327, Percent_Identity=33.3333333333333, Blast_Score=207, Evalue=6e-55,
Organism=Escherichia coli, GI1787948, Length=328, Percent_Identity=30.1829268292683, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1790194, Length=321, Percent_Identity=31.1526479750779, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1788474, Length=301, Percent_Identity=29.2358803986711, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789202, Length=289, Percent_Identity=31.1418685121107, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1789068, Length=299, Percent_Identity=28.0936454849498, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787580, Length=329, Percent_Identity=29.1793313069909, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI48994940, Length=313, Percent_Identity=26.8370607028754, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787906, Length=333, Percent_Identity=23.1231231231231, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1790715, Length=331, Percent_Identity=22.6586102719033, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786268, Length=301, Percent_Identity=26.2458471760797, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786540, Length=332, Percent_Identity=26.5060240963855, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789456, Length=342, Percent_Identity=23.3918128654971, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1790689, Length=297, Percent_Identity=24.9158249158249, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36881; Mature: 36881

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLATIEQLGYRPNAVARGLASKKT
CCEEEEEHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCC
TTVGAIIPDISNIFFSELARGIEDIATMYKYNIILSSSDQNKDKELELINTMLEKQVDGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHCCE
LFMGGNISEEHIHQFQTSSVPVVLASTYDPTDTIPSVNIDYELAAYEATKQLIQKGNKQP
EEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCC
ALVGSKADTSVNNLKTSGYLRALKEANIEVNEDYIYKDEYAYQTGIEAVEYLIGLDDQPN
EEECCCCCCCHHHHHHHHHHHHHHHCCCEECCCEEECCCHHHHHHHHHHHHHHCCCCCCC
AVFVMYDEIALGVIHGAQDKGLDVPNDLEVFGFDNIRLSTMVRPTLTTIVQPTYDIGAVG
EEEEEECCEEEEEEECCCCCCCCCCCCCEEEECCCEEEEEEHHHHHHHHHCCCCCHHHHH
MRLLTKYMNKEQVDEKNVVLPHRIEFRNSTIQ
HHHHHHHHCHHHCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLATIEQLGYRPNAVARGLASKKT
CCEEEEEHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCC
TTVGAIIPDISNIFFSELARGIEDIATMYKYNIILSSSDQNKDKELELINTMLEKQVDGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHCCE
LFMGGNISEEHIHQFQTSSVPVVLASTYDPTDTIPSVNIDYELAAYEATKQLIQKGNKQP
EEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCC
ALVGSKADTSVNNLKTSGYLRALKEANIEVNEDYIYKDEYAYQTGIEAVEYLIGLDDQPN
EEECCCCCCCHHHHHHHHHHHHHHHCCCEECCCEEECCCHHHHHHHHHHHHHHCCCCCCC
AVFVMYDEIALGVIHGAQDKGLDVPNDLEVFGFDNIRLSTMVRPTLTTIVQPTYDIGAVG
EEEEEECCEEEEEEECCCCCCCCCCCCCEEEECCCEEEEEEHHHHHHHHHCCCCCHHHHH
MRLLTKYMNKEQVDEKNVVLPHRIEFRNSTIQ
HHHHHHHHCHHHCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]