Click here to switch to the map view.

The map label for this gene is etfA [H]

Identifier: 23099573

GI number: 23099573

Start: 2151846

End: 2152817

Strand: Reverse

Name: etfA [H]

Synonym: OB2118

Alternate gene names: 23099573

Gene position: 2152817-2151846 (Counterclockwise)

Preceding gene: 23099574

Following gene: 23099572

Centisome position: 59.3

GC content: 36.42

Gene sequence:

>972_bases
ATGAGCGACAAAATTTTAGTAATTGGTGAATTGAGAGATGACGAAGTACGTAACGTTTCATACGAAGCGATTGCTGCTGC
TAAAAAGATTGATCATAATGCAGAAATTGTAGGGCTGTTAATAGGTAGTGGAGATATTGAAAGCCAAGGTCAATCATTAA
TTGCTTACGGTGCTGATCGTGTGATTGTAGTTTCTCACGATAATTTGAAAACGTATACATCAGAAGGTTATGGGCAAGCA
GTTATGGAAGTGGTTAATAATGAATCTCCTACAGGAATAGTTATGGGACACACTTCGATTGGAAAAGATTTAACTCCAAA
AATTGCTAGTAAATTAAACACTGGACTTGTATCCGATGTGGTAGATATCGAAGATGATGGTGTATTTGTACGTCCGATTT
ATTCTGGAAAAGCATTTGAAAAAAAGGTTATCACGGATGGGATTACTTTTATAACAATACGTCCAAACAATATACCTGCG
CTTGAGAAAGATGGATCTAGATCAGGAGAAGTTAGCTCTGTAGATGTGAATATTACTGATTTACGAACAGTAATTAAAGA
TGTTATTAGAAAAGCATCTGAAGGAGTGGATTTATCTGAAGCAAATGTAATTGTAGCAGGTGGTAGAGGTGTAAAAAGTG
CGGATGGCTTCAAACCATTATATGAATTAGCGGAAGTACTTGGAGGTGCAGTTGGTGCTTCACGTGGTGCATGTGATGCA
GACTACTGTGATTATGCACTTCAAATTGGTCAAACTGGTAAAGTAGTAACTCCAGATTTATATATTGCAGTAGGAATATC
TGGAGCGATCCAACACTTAGCGGGGATGTCAAACTCGAAAGTAATCGTTGCTATAAACAAGGATCCTGAATCCAATATTT
TTAATGTAGCGGATTATGGTATAGTTGGAGATCTATTTGAAGTCATTCCATTGCTTATTGAAGAAATAAAAAAAGTTAAA
GTGACAGTTTAA

Upstream 100 bases:

>100_bases
CTCGAAGGGGAACCTGCTGATCAAGTGAAAGAATTAGTATCCTTATTGAAAAACGAGAAAAAAGTACTTTAATGTTTTAT
TGCAGAAAGGGGCTTAAATA

Downstream 100 bases:

>100_bases
TCTAAGAGACAATAGGGTTTGCATGAAAGCTTTCATAGATTAATAGCTAACCCTATTGTCTTTAATAATACTCATCTAAA
ATTCAACAATTTCTCAAAAA

Product: electron transfer flavoprotein alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSDKILVIGELRDDEVRNVSYEAIAAAKKIDHNAEIVGLLIGSGDIESQGQSLIAYGADRVIVVSHDNLKTYTSEGYGQA
VMEVVNNESPTGIVMGHTSIGKDLTPKIASKLNTGLVSDVVDIEDDGVFVRPIYSGKAFEKKVITDGITFITIRPNNIPA
LEKDGSRSGEVSSVDVNITDLRTVIKDVIRKASEGVDLSEANVIVAGGRGVKSADGFKPLYELAEVLGGAVGASRGACDA
DYCDYALQIGQTGKVVTPDLYIAVGISGAIQHLAGMSNSKVIVAINKDPESNIFNVADYGIVGDLFEVIPLLIEEIKKVK
VTV

Sequences:

>Translated_323_residues
MSDKILVIGELRDDEVRNVSYEAIAAAKKIDHNAEIVGLLIGSGDIESQGQSLIAYGADRVIVVSHDNLKTYTSEGYGQA
VMEVVNNESPTGIVMGHTSIGKDLTPKIASKLNTGLVSDVVDIEDDGVFVRPIYSGKAFEKKVITDGITFITIRPNNIPA
LEKDGSRSGEVSSVDVNITDLRTVIKDVIRKASEGVDLSEANVIVAGGRGVKSADGFKPLYELAEVLGGAVGASRGACDA
DYCDYALQIGQTGKVVTPDLYIAVGISGAIQHLAGMSNSKVIVAINKDPESNIFNVADYGIVGDLFEVIPLLIEEIKKVK
VTV
>Mature_322_residues
SDKILVIGELRDDEVRNVSYEAIAAAKKIDHNAEIVGLLIGSGDIESQGQSLIAYGADRVIVVSHDNLKTYTSEGYGQAV
MEVVNNESPTGIVMGHTSIGKDLTPKIASKLNTGLVSDVVDIEDDGVFVRPIYSGKAFEKKVITDGITFITIRPNNIPAL
EKDGSRSGEVSSVDVNITDLRTVIKDVIRKASEGVDLSEANVIVAGGRGVKSADGFKPLYELAEVLGGAVGASRGACDAD
YCDYALQIGQTGKVVTPDLYIAVGISGAIQHLAGMSNSKVIVAINKDPESNIFNVADYGIVGDLFEVIPLLIEEIKKVKV
TV

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=314, Percent_Identity=39.8089171974522, Blast_Score=212, Evalue=4e-55,
Organism=Homo sapiens, GI189181759, Length=262, Percent_Identity=42.3664122137405, Blast_Score=205, Evalue=3e-53,
Organism=Escherichia coli, GI1787990, Length=274, Percent_Identity=33.5766423357664, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786226, Length=249, Percent_Identity=29.718875502008, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI87082157, Length=228, Percent_Identity=27.1929824561404, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17506929, Length=311, Percent_Identity=40.1929260450161, Blast_Score=212, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6325261, Length=270, Percent_Identity=37.7777777777778, Blast_Score=187, Evalue=2e-48,
Organism=Drosophila melanogaster, GI17136898, Length=311, Percent_Identity=41.1575562700965, Blast_Score=218, Evalue=6e-57,
Organism=Drosophila melanogaster, GI24652801, Length=311, Percent_Identity=41.1575562700965, Blast_Score=218, Evalue=6e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 34207; Mature: 34076

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00018 EF_HAND_1 ; PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKILVIGELRDDEVRNVSYEAIAAAKKIDHNAEIVGLLIGSGDIESQGQSLIAYGADR
CCCCEEEEEECCCCHHHCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEEEEECCCE
VIVVSHDNLKTYTSEGYGQAVMEVVNNESPTGIVMGHTSIGKDLTPKIASKLNTGLVSDV
EEEEECCCCEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHCCCHHHHH
VDIEDDGVFVRPIYSGKAFEKKVITDGITFITIRPNNIPALEKDGSRSGEVSSVDVNITD
EEECCCCEEEEEECCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHH
LRTVIKDVIRKASEGVDLSEANVIVAGGRGVKSADGFKPLYELAEVLGGAVGASRGACDA
HHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
DYCDYALQIGQTGKVVTPDLYIAVGISGAIQHLAGMSNSKVIVAINKDPESNIFNVADYG
HHHHHHHEECCCCCEECCCEEEEEECHHHHHHHHCCCCCEEEEEECCCCCCCEEECHHHH
IVGDLFEVIPLLIEEIKKVKVTV
HHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure 
SDKILVIGELRDDEVRNVSYEAIAAAKKIDHNAEIVGLLIGSGDIESQGQSLIAYGADR
CCCEEEEEECCCCHHHCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEEEEECCCE
VIVVSHDNLKTYTSEGYGQAVMEVVNNESPTGIVMGHTSIGKDLTPKIASKLNTGLVSDV
EEEEECCCCEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHCCCHHHHH
VDIEDDGVFVRPIYSGKAFEKKVITDGITFITIRPNNIPALEKDGSRSGEVSSVDVNITD
EEECCCCEEEEEECCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHH
LRTVIKDVIRKASEGVDLSEANVIVAGGRGVKSADGFKPLYELAEVLGGAVGASRGACDA
HHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
DYCDYALQIGQTGKVVTPDLYIAVGISGAIQHLAGMSNSKVIVAINKDPESNIFNVADYG
HHHHHHHEECCCCCEECCCEEEEEECHHHHHHHHCCCCCEEEEEECCCCCCCEEECHHHH
IVGDLFEVIPLLIEEIKKVKVTV
HHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]