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The map label for this gene is ccdA [H]

Identifier: 23099132

GI number: 23099132

Start: 1718349

End: 1719053

Strand: Direct

Name: ccdA [H]

Synonym: OB1677

Alternate gene names: 23099132

Gene position: 1718349-1719053 (Clockwise)

Preceding gene: 23099131

Following gene: 23099133

Centisome position: 47.33

GC content: 32.62

Gene sequence:

>705_bases
ATGTCAGAAATTAATATTTTTCTTGCCTTTAGTGCAGGATTTCTATCGTTTATATCGCCTTGTGTGTTACCGCTTTATCC
AATTTTTCTTTCATATATCACTGGTATGAGTATGAATGAAATTACAGATGACAATAAACGAATGGATAAAAAAGCAATAC
TACATACACTTTGTTTTCTAATCGGATTTTCTAGTATTTTCATTATGATTGGTTTTACCACAACGTTTATTTCTGAGTTT
TTAATGACCTATCAGGCAACAATCAGACAAGTTGGGGCTATATTAATAATATTTTTTGGCCTTGTCATTGTCGGAGTATT
GAATTTTGAATTTCTGATGAAAGATCGAAAAATTCATTTTAAAAATCGTCCCGCAGGATATATTGGATCTCTATTAATAG
GGATGGCTTTTTCATTGGGATGGACTCCATGTACTGGACCAATATTAGCAATTGTCTTGTCACTAGCAGCTACACAACCG
GATATTGGTATGATTATGATGATAAGTTACATATTAGGTTTTTCTATTCCATTCTTCGTACTCGCATTTTTCATTGGAAA
ATTAACCTGGTTTAAAAAACATAGTCAGTTGTTAGTAAAAATAGGTGGCTGGGTGATGATTTTGATGGGAATCGCATTAT
TTTTTGATTGGATGACGAAGCTAACTTCTTATCTAGCATCCTTATTTGGTTTTTCGGGTTTCTAA

Upstream 100 bases:

>100_bases
AAAAAATGAATAAAATGTATAGATATTGTCATAATATCTTCTTTTATTTAATAATACATCTGTTAAAATAGAAATTGACT
TGTTAGGGGGCAGTTAGCTT

Downstream 100 bases:

>100_bases
TTATACTATATAATGTATAATAGACTGTAGAATAATTCATAGTAATCATTTTAGTTCAGCTTAGGGAAAGAGTGATACCA
TGTATTGGGCAATAGCAAGT

Product: holocytochrome c synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSEINIFLAFSAGFLSFISPCVLPLYPIFLSYITGMSMNEITDDNKRMDKKAILHTLCFLIGFSSIFIMIGFTTTFISEF
LMTYQATIRQVGAILIIFFGLVIVGVLNFEFLMKDRKIHFKNRPAGYIGSLLIGMAFSLGWTPCTGPILAIVLSLAATQP
DIGMIMMISYILGFSIPFFVLAFFIGKLTWFKKHSQLLVKIGGWVMILMGIALFFDWMTKLTSYLASLFGFSGF

Sequences:

>Translated_234_residues
MSEINIFLAFSAGFLSFISPCVLPLYPIFLSYITGMSMNEITDDNKRMDKKAILHTLCFLIGFSSIFIMIGFTTTFISEF
LMTYQATIRQVGAILIIFFGLVIVGVLNFEFLMKDRKIHFKNRPAGYIGSLLIGMAFSLGWTPCTGPILAIVLSLAATQP
DIGMIMMISYILGFSIPFFVLAFFIGKLTWFKKHSQLLVKIGGWVMILMGIALFFDWMTKLTSYLASLFGFSGF
>Mature_233_residues
SEINIFLAFSAGFLSFISPCVLPLYPIFLSYITGMSMNEITDDNKRMDKKAILHTLCFLIGFSSIFIMIGFTTTFISEFL
MTYQATIRQVGAILIIFFGLVIVGVLNFEFLMKDRKIHFKNRPAGYIGSLLIGMAFSLGWTPCTGPILAIVLSLAATQPD
IGMIMMISYILGFSIPFFVLAFFIGKLTWFKKHSQLLVKIGGWVMILMGIALFFDWMTKLTSYLASLFGFSGF

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 26252; Mature: 26121

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEINIFLAFSAGFLSFISPCVLPLYPIFLSYITGMSMNEITDDNKRMDKKAILHTLCFL
CCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHH
IGFSSIFIMIGFTTTFISEFLMTYQATIRQVGAILIIFFGLVIVGVLNFEFLMKDRKIHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCC
KNRPAGYIGSLLIGMAFSLGWTPCTGPILAIVLSLAATQPDIGMIMMISYILGFSIPFFV
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHH
LAFFIGKLTWFKKHSQLLVKIGGWVMILMGIALFFDWMTKLTSYLASLFGFSGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SEINIFLAFSAGFLSFISPCVLPLYPIFLSYITGMSMNEITDDNKRMDKKAILHTLCFL
CCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHH
IGFSSIFIMIGFTTTFISEFLMTYQATIRQVGAILIIFFGLVIVGVLNFEFLMKDRKIHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCC
KNRPAGYIGSLLIGMAFSLGWTPCTGPILAIVLSLAATQPDIGMIMMISYILGFSIPFFV
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHH
LAFFIGKLTWFKKHSQLLVKIGGWVMILMGIALFFDWMTKLTSYLASLFGFSGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]