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The map label for this gene is 23099080

Identifier: 23099080

GI number: 23099080

Start: 1664607

End: 1666169

Strand: Direct

Name: 23099080

Synonym: OB1625

Alternate gene names: NA

Gene position: 1664607-1666169 (Clockwise)

Preceding gene: 23099079

Following gene: 23099081

Centisome position: 45.85

GC content: 41.01

Gene sequence:

>1563_bases
ATGGACATCGTTATCGTCGTCATCTCCATTTTGCTTGCTCTGATCGTCGGTATTGTTGTTGGTTATCTGGTACGCAGATC
TATTGCAGAAGCAAAGATCTCTAGTGCGGAGAGACTTGCAAAGCAAATTGTCGAAGAAGCACACAGAAATGCAGATGCCG
CCAAGAAAGAAGCGCTTCTTGAAGCAAAAGATGAAACTCATAAATTCCGTCAACAAGCGGAAGATGAAATAAGAGAGCGC
CGCATGGAAGCTCAGAAGCAAGAAAATCGTCTGATGCAAAAAGAAGAGAATCTGGACCGAAAAAGTGAAACCTTAGACAA
ACGTGAGTCGAGTTTAGAGAGTAAAGAACAATCTCTAACCGAACAACAACAACAAATTGAAGAAATGAAAAGCAAAGTGG
AAGCTATGAAAGACGAGCAGCAAGCTGAGCTTGAGCGCATTTCAGGATATACATCTGAACAGGCGAAACAGATTATTTTA
GAGCGTATCGAAAAAGAGGTACAGCATGAATCAGCAGTGTTGATTAAAGAGTCTGAAACACGTGCAAAAGAGGAAGCTGA
TAAAAAAGCCAAAAACATTTTATCCCTTGCCTTACAGCGTTGTGCTGCAGACCATGTTGCTGAGACAACGGTTTCTGTTG
TTAATTTGCCGAATGATGAAATGAAAGGTCGTATCATTGGTCGTGAAGGTAGAAACATAAGAACTCTAGAAACCTTAACT
GGAATTGATTTAATTATAGATGACACTCCAGAAGCAGTTATACTCTCTGGTTTCGATCCAATTCGACGTGAAATTGCACG
TATGGCATTAGAAAAGCTCGTGCAAGATGGAAGAATACACCCTGCACGTATCGAAGAAATGGTTGAGAAATCTAGACGCG
AAGTAGACGAATATATTCGAGAAGTAGGCGAGGAAACTACTTTCGAAGTTGGAGTTCACGGATTACATCCGGATCTAGTG
AAAATCTTAGGTCGTCTAAAATATCGTACAAGCTATGGTCAGAACGGACTGAAACACTCGGCAGAAGTTGCTTACTTGTC
AGGACTGTTAGCGGCTGAACTTGGAGAAGATGTGACACTAGCTAGAAGAGCTGGTCTACTGCATGATATCGGGAAAGCTA
TCGACCATGAAGTAGAAGGAAGTCATGTTGAAATAGGTAAAGAGCTAGCGATGAAGTATAAAGAACACGAAGTCGTGATT
AATTCAATTGCTTCCCACCATGGAGATGAAGAAGCAACATCTATTATTGCAGTATTGGTTGCTGCTGCGGACGCATTATC
TGCAGCGAGACCTGGTGCTAGAAGTGAAACGCTGGAAAATTACATTAAACGACTAGAGAAACTAGAAGAAATCTCAGAAT
CCTTTGATGGCGTTGAAAAATCATTTGCTATTCAAGCGGGTAGAGAAATTCGTATCATGGTTAGACCTGATGAAATAGAT
GATATTGAATCTATAAGCATCGCACGTGATATCCGCAAGCGAATTGAAGGCGAACTTGACTATCCTGGACATATAAAAGT
TACTGTAATAAGGGAAACAAGAGCAGTTGAATACGCGAAATAA

Upstream 100 bases:

>100_bases
TATAATTTCCATTATGAAATTAATATTTGATGCATTTAGAAAATGTTACATGCCGACACATATGAAATGTATAATTTTAT
AGGCAATAGGAGGTGAAATC

Downstream 100 bases:

>100_bases
GTACAGTGGCTGATATATTATACGTCGCTGTAAGAAAAAATCCGGTTATCTAATTGATAACCGGATTTTTTAGCATTATC
GGTTTGACTATGTATCTCTT

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MDIVIVVISILLALIVGIVVGYLVRRSIAEAKISSAERLAKQIVEEAHRNADAAKKEALLEAKDETHKFRQQAEDEIRER
RMEAQKQENRLMQKEENLDRKSETLDKRESSLESKEQSLTEQQQQIEEMKSKVEAMKDEQQAELERISGYTSEQAKQIIL
ERIEKEVQHESAVLIKESETRAKEEADKKAKNILSLALQRCAADHVAETTVSVVNLPNDEMKGRIIGREGRNIRTLETLT
GIDLIIDDTPEAVILSGFDPIRREIARMALEKLVQDGRIHPARIEEMVEKSRREVDEYIREVGEETTFEVGVHGLHPDLV
KILGRLKYRTSYGQNGLKHSAEVAYLSGLLAAELGEDVTLARRAGLLHDIGKAIDHEVEGSHVEIGKELAMKYKEHEVVI
NSIASHHGDEEATSIIAVLVAAADALSAARPGARSETLENYIKRLEKLEEISESFDGVEKSFAIQAGREIRIMVRPDEID
DIESISIARDIRKRIEGELDYPGHIKVTVIRETRAVEYAK

Sequences:

>Translated_520_residues
MDIVIVVISILLALIVGIVVGYLVRRSIAEAKISSAERLAKQIVEEAHRNADAAKKEALLEAKDETHKFRQQAEDEIRER
RMEAQKQENRLMQKEENLDRKSETLDKRESSLESKEQSLTEQQQQIEEMKSKVEAMKDEQQAELERISGYTSEQAKQIIL
ERIEKEVQHESAVLIKESETRAKEEADKKAKNILSLALQRCAADHVAETTVSVVNLPNDEMKGRIIGREGRNIRTLETLT
GIDLIIDDTPEAVILSGFDPIRREIARMALEKLVQDGRIHPARIEEMVEKSRREVDEYIREVGEETTFEVGVHGLHPDLV
KILGRLKYRTSYGQNGLKHSAEVAYLSGLLAAELGEDVTLARRAGLLHDIGKAIDHEVEGSHVEIGKELAMKYKEHEVVI
NSIASHHGDEEATSIIAVLVAAADALSAARPGARSETLENYIKRLEKLEEISESFDGVEKSFAIQAGREIRIMVRPDEID
DIESISIARDIRKRIEGELDYPGHIKVTVIRETRAVEYAK
>Mature_520_residues
MDIVIVVISILLALIVGIVVGYLVRRSIAEAKISSAERLAKQIVEEAHRNADAAKKEALLEAKDETHKFRQQAEDEIRER
RMEAQKQENRLMQKEENLDRKSETLDKRESSLESKEQSLTEQQQQIEEMKSKVEAMKDEQQAELERISGYTSEQAKQIIL
ERIEKEVQHESAVLIKESETRAKEEADKKAKNILSLALQRCAADHVAETTVSVVNLPNDEMKGRIIGREGRNIRTLETLT
GIDLIIDDTPEAVILSGFDPIRREIARMALEKLVQDGRIHPARIEEMVEKSRREVDEYIREVGEETTFEVGVHGLHPDLV
KILGRLKYRTSYGQNGLKHSAEVAYLSGLLAAELGEDVTLARRAGLLHDIGKAIDHEVEGSHVEIGKELAMKYKEHEVVI
NSIASHHGDEEATSIIAVLVAAADALSAARPGARSETLENYIKRLEKLEEISESFDGVEKSFAIQAGREIRIMVRPDEID
DIESISIARDIRKRIEGELDYPGHIKVTVIRETRAVEYAK

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD_OCEIH (Q8EQR7)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692546.1
- ProteinModelPortal:   Q8EQR7
- SMR:   Q8EQR7
- GeneID:   1018120
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1625
- NMPDR:   fig|221109.1.peg.1627
- HOGENOM:   HBG734610
- OMA:   HPGRIEE
- ProtClustDB:   PRK12704
- BioCyc:   OIHE221109:OB1625-MONOMER
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 58626; Mature: 58626

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc5e7fd8)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIVIVVISILLALIVGIVVGYLVRRSIAEAKISSAERLAKQIVEEAHRNADAAKKEALL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EAKDETHKFRQQAEDEIRERRMEAQKQENRLMQKEENLDRKSETLDKRESSLESKEQSLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EQQQQIEEMKSKVEAMKDEQQAELERISGYTSEQAKQIILERIEKEVQHESAVLIKESET
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCHH
RAKEEADKKAKNILSLALQRCAADHVAETTVSVVNLPNDEMKGRIIGREGRNIRTLETLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHCCCEECCCCCCCCHHHHHC
GIDLIIDDTPEAVILSGFDPIRREIARMALEKLVQDGRIHPARIEEMVEKSRREVDEYIR
CCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
EVGEETTFEVGVHGLHPDLVKILGRLKYRTSYGQNGLKHSAEVAYLSGLLAAELGEDVTL
HHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
ARRAGLLHDIGKAIDHEVEGSHVEIGKELAMKYKEHEVVINSIASHHGDEEATSIIAVLV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AAADALSAARPGARSETLENYIKRLEKLEEISESFDGVEKSFAIQAGREIRIMVRPDEID
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCC
DIESISIARDIRKRIEGELDYPGHIKVTVIRETRAVEYAK
CHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHCCCH
>Mature Secondary Structure
MDIVIVVISILLALIVGIVVGYLVRRSIAEAKISSAERLAKQIVEEAHRNADAAKKEALL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EAKDETHKFRQQAEDEIRERRMEAQKQENRLMQKEENLDRKSETLDKRESSLESKEQSLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EQQQQIEEMKSKVEAMKDEQQAELERISGYTSEQAKQIILERIEKEVQHESAVLIKESET
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCHH
RAKEEADKKAKNILSLALQRCAADHVAETTVSVVNLPNDEMKGRIIGREGRNIRTLETLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHCCCEECCCCCCCCHHHHHC
GIDLIIDDTPEAVILSGFDPIRREIARMALEKLVQDGRIHPARIEEMVEKSRREVDEYIR
CCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
EVGEETTFEVGVHGLHPDLVKILGRLKYRTSYGQNGLKHSAEVAYLSGLLAAELGEDVTL
HHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
ARRAGLLHDIGKAIDHEVEGSHVEIGKELAMKYKEHEVVINSIASHHGDEEATSIIAVLV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AAADALSAARPGARSETLENYIKRLEKLEEISESFDGVEKSFAIQAGREIRIMVRPDEID
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCC
DIESISIARDIRKRIEGELDYPGHIKVTVIRETRAVEYAK
CHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12235376