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The map label for this gene is ftsK

Identifier: 23099069

GI number: 23099069

Start: 1651983

End: 1654331

Strand: Direct

Name: ftsK

Synonym: OB1614

Alternate gene names: 23099069

Gene position: 1651983-1654331 (Clockwise)

Preceding gene: 23099068

Following gene: 23099070

Centisome position: 45.5

GC content: 36.87

Gene sequence:

>2349_bases
ATGGCCGCGAAAAAGAGAAAGAAAAAAAGAAAAAATTCAAAGCAAGTAAAACGATTAAAAATAGAGTTAGTTGGCCTACT
TCTTATATTTCTTGCTATATTTGGTAGCGGAGCAGCAGCGCTAAGTGATGGTGCTATACCAGGATGGTTGGAGAATTTAT
TTCAATTCTTCTTCGGTATATGGTATTTTATTGCATCTGTATTTCTGCTTGTAACTGGATTTTACTTATTAGTAAAACGA
AAATTACCAGATTTTCTACACCGAAGAATGATTGGATTTTACATTCTATTAGCGGGTGTACTGATGTTGACGCATATACA
AGTATTGGAGAGTTTACTAGTAACAACAGAAAATACGTCCATTATCGGGATGAGCTGGACGCTATTTTTTGATTATGTAA
ATGGAACTGGTACTTTAGTACAAACTGGTGGAGGAATGATTGGGGCAATCCTTTTTACTTTTTCACACTATATGTTCTCC
ATTACAGGATCTAAAATTGTTGTTGTATTTTGTTTATTAATTGGTGCTATTTTCCTTACTAATTTATCTATTGGAGAAGT
CGCTTCTAAGCTATTTGCGAGGGTAAAAGCTGTTAGCAATATAGCTATAGAAAAATGGACCCAATATCAAACCGAAAGAA
GAGAAAGAAAACAACAAGCATATATGGATGATGAAAGCAGACAAGCTGTAAATGAATCAGAAGATAATATGGTGACAGAG
ATTGAAGTGTCAGAAAGAGAAGAGCCATTTATCAATGATTTTACAGATGTGGCTTATCAAAATAATGCAACACAAGCAAC
AGAGAATAAATCACCAGCTAAACAAGCGCAAAGTATAAAAAGTGATCAAGAAGGGCAATCTGATCACTCAGCTGAGGATA
GTAAAGATGAAGCAATGCCAATGACAGCAAGGGAGAATCATGATTATGAACTTCCTATGCCAGATTTATTAGCAGATCCA
TCTTATAACTCACAACAGCAAGAAAAATCGCAAATCCAAGCTACAGTACGTAAATTGGAAAAAACATTTACAAGTTTTGG
TGTAAAGGCAAAAATAACGAAGGTGCATGTTGGCCCAGCTGTTACGAAATATGAGGTATATCCTGAAGCAGGGGTGAAAG
TTAGTAAGATTGTTAATCTTCATGATGATATAGCACTTGCCTTAGCTGCAAAAGATATACGTATTGAAGCACCAATTCCA
GGGAAATCTGCAGTTGGAATAGAAGTTCCAAATAAAGAAATCGCGATGGTTTCTTTACGTGAAGTGTTAGATAAAACATG
GTCTAATAAAACTTCTAAACTCCTTTATGCACTTGGTAGAGACATATCTGGTGAAGCTGTTGTTGGTGAATTGAATAAAA
TGCCACACCTCTTAATTGCTGGTGCAACAGGAAGCGGGAAAAGTGTGTGTGTAAATGGGATAATTACAAGTATTTTAATG
CGTGCAAAACCTCATGAAGTTAAAATGATGATGATTGATCCTAAAAAAGTAGAACTAAATGTTTATAATGGTATTCCACA
CTTGTTAGCACCAGTTGTAACTGATCCTAAGAAAGCATCAAGAGCATTAAAAAAAGTTGTTGCTGAAATGGAAAGACGAT
ACGACTTATTCTCTGAAACGGGAACAAGAAATATTGAAGGATATAATGAATATATTCGAAAGCAAAATCTAGCATCTGAA
GATCAGCAGCCACACTTACCTTATATTGTTGTTCTTGTGGATGAGTTGGCAGATTTAATGATGGTAGCGTCAAATGATGT
GGAAGATTCTATTACGAGATTGGCGCAAATGGCTCGTGCAGCAGGAATTCACTTAATTATTGCTACACAACGTCCATCGG
TAGATGTTATCACTGGTGTCATTAAAGCAAACATACCGTCACGCATTGCATTTAGTGTATCCTCTGCGACAGATTCACGC
ACGATCCTTGATTCTGGAGGAGCTGAAAAATTATTAGGTAGAGGCGATATGTTATTTATGCCCGTAGGCTCTTCGAAACC
AACACGTGTTCAAGGTGCGTTTTTATCTGATGAAGAGGTAGAACGTATTGTAGACCATTGTGTAGAACAACAAAAAGCAA
CTTATCAAGAAGAAATGATTCCCGAAGAAACAAATGAAGTGGTAGAAGATGTAGATGATGATCTTTTTGAGGATGCGGTT
CAACTTATTTCAGAAATGCAAAGTGCAAGTGTCTCGATGTTACAGCGTCGATTCCGGATTGGATATACTAGAGCTGCGAG
ACTGATTGATGCAATGGAAGATCGAGGAATAGTAGGTCCATATGAAGGGAGTAAACCAAGGTCCGTCTTGGTGCCAAAAC
CTACAGAAGAACAAACAACCTCTTCGTAA

Upstream 100 bases:

>100_bases
TTTCCCAAATCTATGCTATAATGGAAGTAGAAAAACCCTTGCCGCTTTTGTGGGGCAAGGGTTTGCTATTCGCAAAAGTA
ATGGATGTTGGGGTGAGAAA

Downstream 100 bases:

>100_bases
AAGCTTTAATATAATCCTTATTCTAGTAATCTCATGAATAAGGATTATATTTTTGATTGCGAAAATAACTGACAATGAAT
TTGCTTTGTCGAGGAAAAAG

Product: stage III sporulation protein E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 782; Mature: 781

Protein sequence:

>782_residues
MAAKKRKKKRKNSKQVKRLKIELVGLLLIFLAIFGSGAAALSDGAIPGWLENLFQFFFGIWYFIASVFLLVTGFYLLVKR
KLPDFLHRRMIGFYILLAGVLMLTHIQVLESLLVTTENTSIIGMSWTLFFDYVNGTGTLVQTGGGMIGAILFTFSHYMFS
ITGSKIVVVFCLLIGAIFLTNLSIGEVASKLFARVKAVSNIAIEKWTQYQTERRERKQQAYMDDESRQAVNESEDNMVTE
IEVSEREEPFINDFTDVAYQNNATQATENKSPAKQAQSIKSDQEGQSDHSAEDSKDEAMPMTARENHDYELPMPDLLADP
SYNSQQQEKSQIQATVRKLEKTFTSFGVKAKITKVHVGPAVTKYEVYPEAGVKVSKIVNLHDDIALALAAKDIRIEAPIP
GKSAVGIEVPNKEIAMVSLREVLDKTWSNKTSKLLYALGRDISGEAVVGELNKMPHLLIAGATGSGKSVCVNGIITSILM
RAKPHEVKMMMIDPKKVELNVYNGIPHLLAPVVTDPKKASRALKKVVAEMERRYDLFSETGTRNIEGYNEYIRKQNLASE
DQQPHLPYIVVLVDELADLMMVASNDVEDSITRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFSVSSATDSR
TILDSGGAEKLLGRGDMLFMPVGSSKPTRVQGAFLSDEEVERIVDHCVEQQKATYQEEMIPEETNEVVEDVDDDLFEDAV
QLISEMQSASVSMLQRRFRIGYTRAARLIDAMEDRGIVGPYEGSKPRSVLVPKPTEEQTTSS

Sequences:

>Translated_782_residues
MAAKKRKKKRKNSKQVKRLKIELVGLLLIFLAIFGSGAAALSDGAIPGWLENLFQFFFGIWYFIASVFLLVTGFYLLVKR
KLPDFLHRRMIGFYILLAGVLMLTHIQVLESLLVTTENTSIIGMSWTLFFDYVNGTGTLVQTGGGMIGAILFTFSHYMFS
ITGSKIVVVFCLLIGAIFLTNLSIGEVASKLFARVKAVSNIAIEKWTQYQTERRERKQQAYMDDESRQAVNESEDNMVTE
IEVSEREEPFINDFTDVAYQNNATQATENKSPAKQAQSIKSDQEGQSDHSAEDSKDEAMPMTARENHDYELPMPDLLADP
SYNSQQQEKSQIQATVRKLEKTFTSFGVKAKITKVHVGPAVTKYEVYPEAGVKVSKIVNLHDDIALALAAKDIRIEAPIP
GKSAVGIEVPNKEIAMVSLREVLDKTWSNKTSKLLYALGRDISGEAVVGELNKMPHLLIAGATGSGKSVCVNGIITSILM
RAKPHEVKMMMIDPKKVELNVYNGIPHLLAPVVTDPKKASRALKKVVAEMERRYDLFSETGTRNIEGYNEYIRKQNLASE
DQQPHLPYIVVLVDELADLMMVASNDVEDSITRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFSVSSATDSR
TILDSGGAEKLLGRGDMLFMPVGSSKPTRVQGAFLSDEEVERIVDHCVEQQKATYQEEMIPEETNEVVEDVDDDLFEDAV
QLISEMQSASVSMLQRRFRIGYTRAARLIDAMEDRGIVGPYEGSKPRSVLVPKPTEEQTTSS
>Mature_781_residues
AAKKRKKKRKNSKQVKRLKIELVGLLLIFLAIFGSGAAALSDGAIPGWLENLFQFFFGIWYFIASVFLLVTGFYLLVKRK
LPDFLHRRMIGFYILLAGVLMLTHIQVLESLLVTTENTSIIGMSWTLFFDYVNGTGTLVQTGGGMIGAILFTFSHYMFSI
TGSKIVVVFCLLIGAIFLTNLSIGEVASKLFARVKAVSNIAIEKWTQYQTERRERKQQAYMDDESRQAVNESEDNMVTEI
EVSEREEPFINDFTDVAYQNNATQATENKSPAKQAQSIKSDQEGQSDHSAEDSKDEAMPMTARENHDYELPMPDLLADPS
YNSQQQEKSQIQATVRKLEKTFTSFGVKAKITKVHVGPAVTKYEVYPEAGVKVSKIVNLHDDIALALAAKDIRIEAPIPG
KSAVGIEVPNKEIAMVSLREVLDKTWSNKTSKLLYALGRDISGEAVVGELNKMPHLLIAGATGSGKSVCVNGIITSILMR
AKPHEVKMMMIDPKKVELNVYNGIPHLLAPVVTDPKKASRALKKVVAEMERRYDLFSETGTRNIEGYNEYIRKQNLASED
QQPHLPYIVVLVDELADLMMVASNDVEDSITRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFSVSSATDSRT
ILDSGGAEKLLGRGDMLFMPVGSSKPTRVQGAFLSDEEVERIVDHCVEQQKATYQEEMIPEETNEVVEDVDDDLFEDAVQ
LISEMQSASVSMLQRRFRIGYTRAARLIDAMEDRGIVGPYEGSKPRSVLVPKPTEEQTTSS

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain

Homologues:

Organism=Escherichia coli, GI1787117, Length=499, Percent_Identity=47.8957915831663, Blast_Score=423, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSK_OCEIH (Q8EQS7)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692535.1
- ProteinModelPortal:   Q8EQS7
- SMR:   Q8EQS7
- GeneID:   1018109
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1614
- NMPDR:   fig|221109.1.peg.1616
- HOGENOM:   HBG662140
- ProtClustDB:   CLSK873312
- BioCyc:   OIHE221109:OB1614-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- SMART:   SM00382
- SMART:   SM00843

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE

EC number: NA

Molecular weight: Translated: 86826; Mature: 86695

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xefac4a4)-; HASH(0xec211b8)-; HASH(0xe0d5ea8)-; HASH(0xead1550)-; HASH(0xee42150)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKKRKKKRKNSKQVKRLKIELVGLLLIFLAIFGSGAAALSDGAIPGWLENLFQFFFGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHH
WYFIASVFLLVTGFYLLVKRKLPDFLHRRMIGFYILLAGVLMLTHIQVLESLLVTTENTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
IIGMSWTLFFDYVNGTGTLVQTGGGMIGAILFTFSHYMFSITGSKIVVVFCLLIGAIFLT
EEEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
NLSIGEVASKLFARVKAVSNIAIEKWTQYQTERRERKQQAYMDDESRQAVNESEDNMVTE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEE
IEVSEREEPFINDFTDVAYQNNATQATENKSPAKQAQSIKSDQEGQSDHSAEDSKDEAMP
EEECCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
MTARENHDYELPMPDLLADPSYNSQQQEKSQIQATVRKLEKTFTSFGVKAKITKVHVGPA
CCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCC
VTKYEVYPEAGVKVSKIVNLHDDIALALAAKDIRIEAPIPGKSAVGIEVPNKEIAMVSLR
EEEEEECCCCCCCHHHHHHHHHHHHHEEEEECEEEECCCCCCCEEEEECCCCHHHHHHHH
EVLDKTWSNKTSKLLYALGRDISGEAVVGELNKMPHLLIAGATGSGKSVCVNGIITSILM
HHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH
RAKPHEVKMMMIDPKKVELNVYNGIPHLLAPVVTDPKKASRALKKVVAEMERRYDLFSET
HCCCCCEEEEEECCCEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GTRNIEGYNEYIRKQNLASEDQQPHLPYIVVLVDELADLMMVASNDVEDSITRLAQMARA
CCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AGIHLIIATQRPSVDVITGVIKANIPSRIAFSVSSATDSRTILDSGGAEKLLGRGDMLFM
CCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHCCCCHHHHHCCCCEEEE
PVGSSKPTRVQGAFLSDEEVERIVDHCVEQQKATYQEEMIPEETNEVVEDVDDDLFEDAV
ECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QLISEMQSASVSMLQRRFRIGYTRAARLIDAMEDRGIVGPYEGSKPRSVLVPKPTEEQTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCC
SS
CH
>Mature Secondary Structure 
AAKKRKKKRKNSKQVKRLKIELVGLLLIFLAIFGSGAAALSDGAIPGWLENLFQFFFGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHH
WYFIASVFLLVTGFYLLVKRKLPDFLHRRMIGFYILLAGVLMLTHIQVLESLLVTTENTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
IIGMSWTLFFDYVNGTGTLVQTGGGMIGAILFTFSHYMFSITGSKIVVVFCLLIGAIFLT
EEEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
NLSIGEVASKLFARVKAVSNIAIEKWTQYQTERRERKQQAYMDDESRQAVNESEDNMVTE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEE
IEVSEREEPFINDFTDVAYQNNATQATENKSPAKQAQSIKSDQEGQSDHSAEDSKDEAMP
EEECCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
MTARENHDYELPMPDLLADPSYNSQQQEKSQIQATVRKLEKTFTSFGVKAKITKVHVGPA
CCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCC
VTKYEVYPEAGVKVSKIVNLHDDIALALAAKDIRIEAPIPGKSAVGIEVPNKEIAMVSLR
EEEEEECCCCCCCHHHHHHHHHHHHHEEEEECEEEECCCCCCCEEEEECCCCHHHHHHHH
EVLDKTWSNKTSKLLYALGRDISGEAVVGELNKMPHLLIAGATGSGKSVCVNGIITSILM
HHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH
RAKPHEVKMMMIDPKKVELNVYNGIPHLLAPVVTDPKKASRALKKVVAEMERRYDLFSET
HCCCCCEEEEEECCCEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GTRNIEGYNEYIRKQNLASEDQQPHLPYIVVLVDELADLMMVASNDVEDSITRLAQMARA
CCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AGIHLIIATQRPSVDVITGVIKANIPSRIAFSVSSATDSRTILDSGGAEKLLGRGDMLFM
CCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHCCCCHHHHHCCCCEEEE
PVGSSKPTRVQGAFLSDEEVERIVDHCVEQQKATYQEEMIPEETNEVVEDVDDDLFEDAV
ECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QLISEMQSASVSMLQRRFRIGYTRAARLIDAMEDRGIVGPYEGSKPRSVLVPKPTEEQTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCC
SS
CH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12235376