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The map label for this gene is coaD

Identifier: 23098906

GI number: 23098906

Start: 1489194

End: 1489679

Strand: Direct

Name: coaD

Synonym: OB1451

Alternate gene names: 23098906

Gene position: 1489194-1489679 (Clockwise)

Preceding gene: 23098905

Following gene: 23098908

Centisome position: 41.02

GC content: 30.45

Gene sequence:

>486_bases
ATGGGAAAGTTAGCAATATGTCCAGGAAGTTTTGATCCGATTACGAATGGACATCTAGATATTATACAAAGAGGAGCAAA
TGTATTTGAGGAAGTGATTGTAACCGTTTTTAATAATCAGTCAAAGTCTCCTTTATTTTCAGTTACAGAACGGATTGAAT
TATTAGAGGATTCAATTAAGCATATTCCGAATGTTTCAGTTGATTCATCTAGTCGCTTATTAATGGACTATGCTAGAGAG
AAGAAAGCACATGCAGTTATTCGGGGATTAAGAGCAGTAAGCGATTTTGAATATGAAATGCAAATTACTTCTATGAACAG
AAAATTAAATGAAGATATTGAAACCTTGTTTATGATGACTAACAATCAATATTCTTTTTTAAGTTCGAGTATGGTTAAAG
AAATAGCTAAATATGATGGAAATATAAGTGGTTTAGTACCAGAACCAGTAGAAAAAGCATTAAAAGCAAAATTTAATTAT
TTATAA

Upstream 100 bases:

>100_bases
TTCCGCATGAATATGGTCCATTCCAAGCAATAAAACAAGAAAACTATGGCGGCCTAATTAATATCACTATTTATCAAGTT
AATCATGAAGGAGCGTAACT

Downstream 100 bases:

>100_bases
AAATGAATGAGGATGGGCATATCAAAAGTTCTAGTTAAAAGGCGAATGAAAGCTAGAATAAGTGTAAGAAATATACGGAG
ACTCCTTCAATTTTCTGCGT

Product: phosphopantetheine adenyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MGKLAICPGSFDPITNGHLDIIQRGANVFEEVIVTVFNNQSKSPLFSVTERIELLEDSIKHIPNVSVDSSSRLLMDYARE
KKAHAVIRGLRAVSDFEYEMQITSMNRKLNEDIETLFMMTNNQYSFLSSSMVKEIAKYDGNISGLVPEPVEKALKAKFNY
L

Sequences:

>Translated_161_residues
MGKLAICPGSFDPITNGHLDIIQRGANVFEEVIVTVFNNQSKSPLFSVTERIELLEDSIKHIPNVSVDSSSRLLMDYARE
KKAHAVIRGLRAVSDFEYEMQITSMNRKLNEDIETLFMMTNNQYSFLSSSMVKEIAKYDGNISGLVPEPVEKALKAKFNY
L
>Mature_160_residues
GKLAICPGSFDPITNGHLDIIQRGANVFEEVIVTVFNNQSKSPLFSVTERIELLEDSIKHIPNVSVDSSSRLLMDYAREK
KAHAVIRGLRAVSDFEYEMQITSMNRKLNEDIETLFMMTNNQYSFLSSSMVKEIAKYDGNISGLVPEPVEKALKAKFNYL

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=158, Percent_Identity=46.8354430379747, Blast_Score=168, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_OCEIH (Q8ER64)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692372.1
- ProteinModelPortal:   Q8ER64
- SMR:   Q8ER64
- GeneID:   1017691
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1451
- NMPDR:   fig|221109.1.peg.1453
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- BioCyc:   OIHE221109:OB1451-MONOMER
- BRENDA:   2.7.7.3
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18181; Mature: 18050

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLAICPGSFDPITNGHLDIIQRGANVFEEVIVTVFNNQSKSPLFSVTERIELLEDSIK
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
HIPNVSVDSSSRLLMDYAREKKAHAVIRGLRAVSDFEYEMQITSMNRKLNEDIETLFMMT
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
NNQYSFLSSSMVKEIAKYDGNISGLVPEPVEKALKAKFNYL
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GKLAICPGSFDPITNGHLDIIQRGANVFEEVIVTVFNNQSKSPLFSVTERIELLEDSIK
CCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
HIPNVSVDSSSRLLMDYAREKKAHAVIRGLRAVSDFEYEMQITSMNRKLNEDIETLFMMT
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
NNQYSFLSSSMVKEIAKYDGNISGLVPEPVEKALKAKFNYL
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376