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The map label for this gene is dapH

Identifier: 23098857

GI number: 23098857

Start: 1443269

End: 1443979

Strand: Direct

Name: dapH

Synonym: OB1402

Alternate gene names: 23098857

Gene position: 1443269-1443979 (Clockwise)

Preceding gene: 23098856

Following gene: 23098858

Centisome position: 39.75

GC content: 34.46

Gene sequence:

>711_bases
ATGATGGATGCTAATGAAATTATACAATTTATATCAGATAGTAAAAAAAGTACACCTGTAAAGGTATATGTAAAGGGCGA
ATTAGACAAGCTTTCAGCTTCTAATACAATAAAAACCTTTGTTGATTCTAAAAGTGGAACGATATTTGGTGAGTGGAAGG
ACATTCAAGCTTACTTAGAAGAAAATAAATCTTTAATTGAAGACTATATTATTGAAAATGATCGCAGAAATTCGGCTATT
CCCATGCTTGATTTGAAAAATATTAATGCTCGTATTGAACCTGGTGCAATCATTCGTGACCAAGTTGAAATTGGTGATGG
TGCTGTTATTATGATGGGAGCTTCGATTAATATTGGATCAGTTATTGGCGAAGGAACTATGATAGATATGAATGCAGTAT
TAGGCGGTAGAGCAACTGTAGGTAAGAATTGTCATATTGGAGCAGGTTCTGTTCTTGCAGGGGTAATTGAGCCACCTTCT
GCTAAACCAGTAATTGTAGAAGATGATGTTGTGATTGGAGCTAACGTAGTAATTCTAGAAGGAATTACTGTTGGAAAAGG
ATCTATTGTTGCAGCTGGTTCAATTGTGACAAAAGATGTTGCTCCTAATACGCTTGTTGGTGGAACACCAGCAAAAGTAT
TAAAGGAAATTGATGAACAGACAAAATCTAAAACTGAAATTAAACAAGAGCTTCGTAAATTAGATAATTAA

Upstream 100 bases:

>100_bases
TTTTGAATTCTAGTACCAAAATCTACATAGTCTTAGTTGCGACATAACTTACCGTCTGCTAAAGTAATAAAGAGATTATA
ATATTGGAGGAATAGAAATA

Downstream 100 bases:

>100_bases
GGTTGCTGCAGGTATGATGTTACAATTAGAACAAATTCGAAGAGATTTACATCAAATACCAGAATTAGGCTTTCAGGAAT
TTAAAACGCAAGCGTATCTA

Product: tetrahydrodipicolinate succinylase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-acetyltransferase; THP acetyltransferase; Tetrahydropicolinate acetylase

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MMDANEIIQFISDSKKSTPVKVYVKGELDKLSASNTIKTFVDSKSGTIFGEWKDIQAYLEENKSLIEDYIIENDRRNSAI
PMLDLKNINARIEPGAIIRDQVEIGDGAVIMMGASINIGSVIGEGTMIDMNAVLGGRATVGKNCHIGAGSVLAGVIEPPS
AKPVIVEDDVVIGANVVILEGITVGKGSIVAAGSIVTKDVAPNTLVGGTPAKVLKEIDEQTKSKTEIKQELRKLDN

Sequences:

>Translated_236_residues
MMDANEIIQFISDSKKSTPVKVYVKGELDKLSASNTIKTFVDSKSGTIFGEWKDIQAYLEENKSLIEDYIIENDRRNSAI
PMLDLKNINARIEPGAIIRDQVEIGDGAVIMMGASINIGSVIGEGTMIDMNAVLGGRATVGKNCHIGAGSVLAGVIEPPS
AKPVIVEDDVVIGANVVILEGITVGKGSIVAAGSIVTKDVAPNTLVGGTPAKVLKEIDEQTKSKTEIKQELRKLDN
>Mature_236_residues
MMDANEIIQFISDSKKSTPVKVYVKGELDKLSASNTIKTFVDSKSGTIFGEWKDIQAYLEENKSLIEDYIIENDRRNSAI
PMLDLKNINARIEPGAIIRDQVEIGDGAVIMMGASINIGSVIGEGTMIDMNAVLGGRATVGKNCHIGAGSVLAGVIEPPS
AKPVIVEDDVVIGANVVILEGITVGKGSIVAAGSIVTKDVAPNTLVGGTPAKVLKEIDEQTKSKTEIKQELRKLDN

Specific function: Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. DapH subfamily

Homologues:

Organism=Escherichia coli, GI1786362, Length=176, Percent_Identity=30.6818181818182, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786537, Length=61, Percent_Identity=44.2622950819672, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPH_OCEIH (Q8ERA4)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692323.1
- HSSP:   P50870
- ProteinModelPortal:   Q8ERA4
- SMR:   Q8ERA4
- GeneID:   1017627
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1402
- NMPDR:   fig|221109.1.peg.1408
- HOGENOM:   HBG704071
- OMA:   KNAVIMM
- BioCyc:   OIHE221109:OB1402-MONOMER
- HAMAP:   MF_01691
- InterPro:   IPR013710
- InterPro:   IPR018357
- InterPro:   IPR019873
- InterPro:   IPR011004
- TIGRFAMs:   TIGR03532

Pfam domain/function: PF08503 DapD_N; SSF51161 Trimer_LpxA_like

EC number: =2.3.1.89

Molecular weight: Translated: 25076; Mature: 25076

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDANEIIQFISDSKKSTPVKVYVKGELDKLSASNTIKTFVDSKSGTIFGEWKDIQAYLE
CCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHEEEECCCCCEEEECHHHHHHHHH
ENKSLIEDYIIENDRRNSAIPMLDLKNINARIEPGAIIRDQVEIGDGAVIMMGASINIGS
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCEECCCCEEEEEEEECCCEEEEEECCCCCCC
VIGEGTMIDMNAVLGGRATVGKNCHIGAGSVLAGVIEPPSAKPVIVEDDVVIGANVVILE
EECCCEEEEEHHHCCCCCCCCCCCCCCCCHHHEEEECCCCCCCEEEECCEEECCCEEEEE
GITVGKGSIVAAGSIVTKDVAPNTLVGGTPAKVLKEIDEQTKSKTEIKQELRKLDN
EEEECCCCEEEECCEEECCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMDANEIIQFISDSKKSTPVKVYVKGELDKLSASNTIKTFVDSKSGTIFGEWKDIQAYLE
CCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHEEEECCCCCEEEECHHHHHHHHH
ENKSLIEDYIIENDRRNSAIPMLDLKNINARIEPGAIIRDQVEIGDGAVIMMGASINIGS
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCEECCCCEEEEEEEECCCEEEEEECCCCCCC
VIGEGTMIDMNAVLGGRATVGKNCHIGAGSVLAGVIEPPSAKPVIVEDDVVIGANVVILE
EECCCEEEEEHHHCCCCCCCCCCCCCCCCHHHEEEECCCCCCCEEEECCEEECCCEEEEE
GITVGKGSIVAAGSIVTKDVAPNTLVGGTPAKVLKEIDEQTKSKTEIKQELRKLDN
EEEECCCCEEEECCEEECCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376