Click here to switch to the map view.

The map label for this gene is spxA2

Identifier: 23098818

GI number: 23098818

Start: 1412328

End: 1412735

Strand: Direct

Name: spxA2

Synonym: OB1363

Alternate gene names: 23098818

Gene position: 1412328-1412735 (Clockwise)

Preceding gene: 23098817

Following gene: 23098819

Centisome position: 38.9

GC content: 31.37

Gene sequence:

>408_bases
ATGACAGTCAATATATACGGAGCATCTTGTTCATCAACCAGAAAAGCTCGACAGTGGTTTAAAAAACACGGAATAGCTTA
TAAAGAAAGAAATATATTAAGACAACCGTTAACAATTAATGAATTACAAGAAATCTTACGAATGACGGTAGAAGGAACAG
ATGAGATTATTTCTACACGCTCAAAAATATTTAAGGAACTTAATTTAAATTTAGACGAATTACCATTACAAAAATTATTA
GAATTAATACACGAACACCCTAGGTTATTAAAAAGTCCGATATTAATGGATGAAAAACGTTTTCAAGTAGGCTATCATGA
AGACGATATACGACAATTTCTTCCAAGAAAAACAAGAGAACACTTGTGGTTACAGTGGAAATTAGATCTAGGTCTCGTGA
AAGGTTAA

Upstream 100 bases:

>100_bases
ACTACTTTACCATAGTTTTACCACATTTCGGTGATAAGGTATAGATGTAGGATGCTAGATGTCCTCTTTAAGAATGTCAA
AAAAAATAAGGAGAATGAAC

Downstream 100 bases:

>100_bases
TATGTAGACGAAAAAGGGATGAAGAATCGTTAAGCGGTTTTTCATCCCTTTTTATCCTATATAACAAGATTGAATTATTT
CCATTTCCTAAAACAAATTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MTVNIYGASCSSTRKARQWFKKHGIAYKERNILRQPLTINELQEILRMTVEGTDEIISTRSKIFKELNLNLDELPLQKLL
ELIHEHPRLLKSPILMDEKRFQVGYHEDDIRQFLPRKTREHLWLQWKLDLGLVKG

Sequences:

>Translated_135_residues
MTVNIYGASCSSTRKARQWFKKHGIAYKERNILRQPLTINELQEILRMTVEGTDEIISTRSKIFKELNLNLDELPLQKLL
ELIHEHPRLLKSPILMDEKRFQVGYHEDDIRQFLPRKTREHLWLQWKLDLGLVKG
>Mature_134_residues
TVNIYGASCSSTRKARQWFKKHGIAYKERNILRQPLTINELQEILRMTVEGTDEIISTRSKIFKELNLNLDELPLQKLLE
LIHEHPRLLKSPILMDEKRFQVGYHEDDIRQFLPRKTREHLWLQWKLDLGLVKG

Specific function: Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes invo

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family. Spx subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPX2_OCEIH (Q8ERE2)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692284.1
- ProteinModelPortal:   Q8ERE2
- SMR:   Q8ERE2
- GeneID:   1017543
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1363
- NMPDR:   fig|221109.1.peg.1369
- HOGENOM:   HBG734370
- OMA:   NCNIDEL
- ProtClustDB:   CLSK302082
- BioCyc:   OIHE221109:OB1363-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_01132
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335
- InterPro:   IPR006504
- Gene3D:   G3DSA:3.40.30.10
- TIGRFAMs:   TIGR01617

Pfam domain/function: PF03960 ArsC; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 16090; Mature: 15959

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS51353 ARSC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVNIYGASCSSTRKARQWFKKHGIAYKERNILRQPLTINELQEILRMTVEGTDEIISTR
CEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHH
SKIFKELNLNLDELPLQKLLELIHEHPRLLKSPILMDEKRFQVGYHEDDIRQFLPRKTRE
HHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHCCCCCCCHHHHCCCCHHHHHHHCCHHHHH
HLWLQWKLDLGLVKG
HEEEEEEECCCCCCC
>Mature Secondary Structure 
TVNIYGASCSSTRKARQWFKKHGIAYKERNILRQPLTINELQEILRMTVEGTDEIISTR
EEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHH
SKIFKELNLNLDELPLQKLLELIHEHPRLLKSPILMDEKRFQVGYHEDDIRQFLPRKTRE
HHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHCCCCCCCHHHHCCCCHHHHHHHCCHHHHH
HLWLQWKLDLGLVKG
HEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376