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The map label for this gene is dacC [H]

Identifier: 23098817

GI number: 23098817

Start: 1410707

End: 1412086

Strand: Direct

Name: dacC [H]

Synonym: OB1362

Alternate gene names: 23098817

Gene position: 1410707-1412086 (Clockwise)

Preceding gene: 23098813

Following gene: 23098818

Centisome position: 38.86

GC content: 37.17

Gene sequence:

>1380_bases
GTGAGAGTATTGAAAGAGCTTATAACATATATCAGTAAACAAGAAAAATGGGCAGGGGGGATACTTGGTTTAAGTGTACG
ATCTGCGGATACGGGGGATATTTATTTTAGTCATAATGGAGATATACGTCTTCATCCTGCATCAAATATGAAAATCCTAA
CTGCTGTAGCTGCTTTAAAAATATTAGGGCCCGGCTATAGATTTACCACGGAGATAAGGTTAGAAGGGAAACTTGTTGGA
GATGTGTGGGAAGGAGATGTCTATATTGTCGGAAAAGGCGATCCTACATTGCAATTGAATGATTATCAGAGGTTTGCAAC
TATACTCCATAAGTATGGTATCAGAAAAATTACAGGTAGTATTATTGCGGATGATACATGGTACGATGACATACGTTTAT
CGGAGGATTTAATTTGGTCGGATGCACAATATTATTATGGAGCGGAAGTATCAGCATTAACACTATCTCCTGATAAGGAT
TATGATACTGGGTCTGTAAAAATTATTATTAAACCAGGTCAATTAGGTGATCCTCCTGAGTATCAACTGTATCCTAATAC
ATCTTATGTCATGATAGAGAATCATGCAGTTACCGTAGATCACGCTGAGGAAGAAGAATTGTGCATTACTAGAGAACATA
ATGGTAATCGTATTTATATAAAAGGGAAAATCGGTATTAATCAAGACATAAGGAAAGAGTGGATGGCTGTATGGGGAGTG
ACAGATTATGTAGTAAATACATTTGTGCAAGCATTAAATGAAACGGGGATAACTATAAAGGATAAATCTAAAACAGGAAG
GTCCGTTCCAAGCGGTACAGCGTGTATACATGTACATTCTTCTCCTACATTAGCAGAGATCTTAATCCCATTTATGAAAC
TAAGTAATAATGGAATTGGGGAAATGCTTGTAAAAGAAATGGGACGTTTTGTATATGAAGAAGGTACGTGGGAAGCGGGA
TTGAAGGTAATGAAAGAACAAATTCAGTCCTATGGAGTAAATATGAAGACGTTGCAAATAAAGGATGGTTCCGGAATCTC
GCACAATAATTTGTTACCCGCAAATGAATTGACCCATTTATTACATTGTATTCAAACGGAAGAATGGTTTCCTTTGTTGT
TAGATACTTTACCATTAGCGGGCGAGCAGAATCGAATGGTCGGTGGGACTTTACGAGAACGAATGAAGGGGCTCTCTGTT
AAAGCAAAGACTGGAACAATAGAAGGGGTAAGTACTTTATCTGGGTACATCAAAATGGAAACGGACCAAAGGGTGATCTT
CTCCATTTTGTTGAATAATTTAATTGATGGAGAAATAGGTAAAGAGATTGAGGATGAAATAGTCACTTACTTACATGAAC
ATGAATTAGCAAAGGTATAG

Upstream 100 bases:

>100_bases
ATATGAATTACGGCACGTATATATGTTTACGATTAAAAAGGAATCTCGTTCGTTTCTGTAGAAATATAAATATTAGATAT
AGTTCAACTTGAGAACAGGG

Downstream 100 bases:

>100_bases
TGTTTAAATTTACCACTGTGTCAGTATATGCCTGGTCGGTACAAGGACTTTAGTTTAATCCTCCGTGGGACTAACTTTCA
AAGCTGGAAACGAATGCCTA

Product: penicillin binding protein

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 4a; PBP-4a [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MRVLKELITYISKQEKWAGGILGLSVRSADTGDIYFSHNGDIRLHPASNMKILTAVAALKILGPGYRFTTEIRLEGKLVG
DVWEGDVYIVGKGDPTLQLNDYQRFATILHKYGIRKITGSIIADDTWYDDIRLSEDLIWSDAQYYYGAEVSALTLSPDKD
YDTGSVKIIIKPGQLGDPPEYQLYPNTSYVMIENHAVTVDHAEEEELCITREHNGNRIYIKGKIGINQDIRKEWMAVWGV
TDYVVNTFVQALNETGITIKDKSKTGRSVPSGTACIHVHSSPTLAEILIPFMKLSNNGIGEMLVKEMGRFVYEEGTWEAG
LKVMKEQIQSYGVNMKTLQIKDGSGISHNNLLPANELTHLLHCIQTEEWFPLLLDTLPLAGEQNRMVGGTLRERMKGLSV
KAKTGTIEGVSTLSGYIKMETDQRVIFSILLNNLIDGEIGKEIEDEIVTYLHEHELAKV

Sequences:

>Translated_459_residues
MRVLKELITYISKQEKWAGGILGLSVRSADTGDIYFSHNGDIRLHPASNMKILTAVAALKILGPGYRFTTEIRLEGKLVG
DVWEGDVYIVGKGDPTLQLNDYQRFATILHKYGIRKITGSIIADDTWYDDIRLSEDLIWSDAQYYYGAEVSALTLSPDKD
YDTGSVKIIIKPGQLGDPPEYQLYPNTSYVMIENHAVTVDHAEEEELCITREHNGNRIYIKGKIGINQDIRKEWMAVWGV
TDYVVNTFVQALNETGITIKDKSKTGRSVPSGTACIHVHSSPTLAEILIPFMKLSNNGIGEMLVKEMGRFVYEEGTWEAG
LKVMKEQIQSYGVNMKTLQIKDGSGISHNNLLPANELTHLLHCIQTEEWFPLLLDTLPLAGEQNRMVGGTLRERMKGLSV
KAKTGTIEGVSTLSGYIKMETDQRVIFSILLNNLIDGEIGKEIEDEIVTYLHEHELAKV
>Mature_459_residues
MRVLKELITYISKQEKWAGGILGLSVRSADTGDIYFSHNGDIRLHPASNMKILTAVAALKILGPGYRFTTEIRLEGKLVG
DVWEGDVYIVGKGDPTLQLNDYQRFATILHKYGIRKITGSIIADDTWYDDIRLSEDLIWSDAQYYYGAEVSALTLSPDKD
YDTGSVKIIIKPGQLGDPPEYQLYPNTSYVMIENHAVTVDHAEEEELCITREHNGNRIYIKGKIGINQDIRKEWMAVWGV
TDYVVNTFVQALNETGITIKDKSKTGRSVPSGTACIHVHSSPTLAEILIPFMKLSNNGIGEMLVKEMGRFVYEEGTWEAG
LKVMKEQIQSYGVNMKTLQIKDGSGISHNNLLPANELTHLLHCIQTEEWFPLLLDTLPLAGEQNRMVGGTLRERMKGLSV
KAKTGTIEGVSTLSGYIKMETDQRVIFSILLNNLIDGEIGKEIEDEIVTYLHEHELAKV

Specific function: Catalyzes DD-carboxypeptidase and transpeptidation reactions [H]

COG id: COG2027

COG function: function code M; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)

Gene ontology:

Cell location: Secreted (Probable). Note=May be anchored in the membrane via a C-terminal amphiphatic alpha helix [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S13 family [H]

Homologues:

Organism=Escherichia coli, GI1789573, Length=421, Percent_Identity=27.3159144893112, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR000667 [H]

Pfam domain/function: PF02113 Peptidase_S13 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 51397; Mature: 51397

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLKELITYISKQEKWAGGILGLSVRSADTGDIYFSHNGDIRLHPASNMKILTAVAALK
CHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEECCCCEEEECCCCCCHHHHHHHHH
ILGPGYRFTTEIRLEGKLVGDVWEGDVYIVGKGDPTLQLNDYQRFATILHKYGIRKITGS
HCCCCCEEEEEEEEEEEEEEEEECCCEEEEECCCCEEEECCHHHHHHHHHHHCHHHCCCC
IIADDTWYDDIRLSEDLIWSDAQYYYGAEVSALTLSPDKDYDTGSVKIIIKPGQLGDPPE
EEECCCCCCCEECCCHHEECCCCEEECCEEEEEEECCCCCCCCCEEEEEEECCCCCCCCC
YQLYPNTSYVMIENHAVTVDHAEEEELCITREHNGNRIYIKGKIGINQDIRKEWMAVWGV
EEEECCCEEEEEECCEEEECCCCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHCH
TDYVVNTFVQALNETGITIKDKSKTGRSVPSGTACIHVHSSPTLAEILIPFMKLSNNGIG
HHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCHH
EMLVKEMGRFVYEEGTWEAGLKVMKEQIQSYGVNMKTLQIKDGSGISHNNLLPANELTHL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHH
LHCIQTEEWFPLLLDTLPLAGEQNRMVGGTLRERMKGLSVKAKTGTIEGVSTLSGYIKME
HHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCCHHHCCCEEEEC
TDQRVIFSILLNNLIDGEIGKEIEDEIVTYLHEHELAKV
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVLKELITYISKQEKWAGGILGLSVRSADTGDIYFSHNGDIRLHPASNMKILTAVAALK
CHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEECCCCEEEECCCCCCHHHHHHHHH
ILGPGYRFTTEIRLEGKLVGDVWEGDVYIVGKGDPTLQLNDYQRFATILHKYGIRKITGS
HCCCCCEEEEEEEEEEEEEEEEECCCEEEEECCCCEEEECCHHHHHHHHHHHCHHHCCCC
IIADDTWYDDIRLSEDLIWSDAQYYYGAEVSALTLSPDKDYDTGSVKIIIKPGQLGDPPE
EEECCCCCCCEECCCHHEECCCCEEECCEEEEEEECCCCCCCCCEEEEEEECCCCCCCCC
YQLYPNTSYVMIENHAVTVDHAEEEELCITREHNGNRIYIKGKIGINQDIRKEWMAVWGV
EEEECCCEEEEEECCEEEECCCCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHCH
TDYVVNTFVQALNETGITIKDKSKTGRSVPSGTACIHVHSSPTLAEILIPFMKLSNNGIG
HHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCHH
EMLVKEMGRFVYEEGTWEAGLKVMKEQIQSYGVNMKTLQIKDGSGISHNNLLPANELTHL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHH
LHCIQTEEWFPLLLDTLPLAGEQNRMVGGTLRERMKGLSVKAKTGTIEGVSTLSGYIKME
HHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCCHHHCCCEEEEC
TDQRVIFSILLNNLIDGEIGKEIEDEIVTYLHEHELAKV
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7711903; 9384377 [H]