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The map label for this gene is ycnB [H]

Identifier: 23097943

GI number: 23097943

Start: 516597

End: 518009

Strand: Direct

Name: ycnB [H]

Synonym: OB0488

Alternate gene names: 23097943

Gene position: 516597-518009 (Clockwise)

Preceding gene: 23097939

Following gene: 23097946

Centisome position: 14.23

GC content: 37.79

Gene sequence:

>1413_bases
GTGAATCAAATCCATCGACCAACCGTAGTAGCACTATTATTAGCTGGTTCTTTTATTGCAATTTTAAATCAAACGCTAAT
GATAACAGCCATTCCCCCAATAATTATAGAAATGGGTATTACGGCAAATAGTGCTCAATGGTTAACAACAGTTTTTATGC
TTGTAAATGGAATCATGATTCCAGTAAGTGCGTTCTTGATTGAACGATTTACAACCAGACAATTATTTATGTCATCAATG
GGGATCTTTGCTATAGGAACATTAGTGGCAGGTGTAGCCCCTGTTTTTGAGATGTTATTAGTTGGAAGAGTTATTCAATC
TATTGGAGCAGGGGTAATGCTGCCACTTATGACGACAGTATTCTTACTGATTTTTCCAATTAATCGCCGTGGCTCTGTAA
TGGGGTTAATTGGTTTAGTTATTTCTTTTGCTCCAGCTATCGGTCCAGCATTATCCGGATGGGTAACAGGACATTTTTCT
TGGAGATATTTGTTCTTTATTATCTTCCCGATTGCAGTCATTGATATGATTATCGCTTACTTTGCTTTAAAAAATGTAAC
AGAGGTAAAAAAGACAAAGCTCGATATCCCATCGGTTATTCTATCTTCGTTTGGGTTTGGTGGAATTTTATATGGTGTGA
CCAATGCAGGGAATTATGGCTGGGGAGCATCAATTACACTAATAACACTGGCTATTGGCGTTATCTCATTAACATTATTT
ATTTTGAGACAGTTAAAACTAACACATCCAATGCTAGAATTTCGTGTGTTCAAATATGCCATTTTCCCGTTCAGTGTTTT
TATTGGTTCGATAACATTTATGGGACTTATTGGTACAGAGACGTTAATTCCATTATTTATGCAGAATATGCGTGAATTCA
GTGCATTTCAAGCGGGGATGGCAATGTTGCCAGGTGCATTAGTAACTGGATTTCTAGCACCTATAATTGGTAGAATGTTT
GATCGATATGGTGGTAAGTGGATTGTCCTTCCAGGTGTAGTCATAATTACCTTGGCCACTGTTCCATTCATTTTTATAGA
TACAGAAACGACGTTTGCATTTATAACTACTTTGTATGCCGTTCGAATGTTAGGTTTAGCATTGATTATGATGCCGATAC
AGACTGCTGCACTGAATCAGCTGCCTAATAATTTAATACCTCATGGAGCAGCAATGGATGGTACGATGCGTATGACAGCA
GCTTCTGTAGGAACTGCTGTCTTGGTTACTGTAATGACCTCAGTAGAATCCATGGCAGAAAATCAAGTGGCTCGCCCGGA
TATTTTAGGTGTGAATGTGTCATTTTCTGTAATTGCAGTGTTAGGACTATGTACGATTATTGCCTATTTCTTTATTAAGT
TCGACCCATCACCGGCTAAAATAGCAAAGATGGAAGAAGACAAGTCAAATTAA

Upstream 100 bases:

>100_bases
TAAAATAAACTTTAAAATATTTTTATAGATTCTTTACGGGTTTTCGTTTAATCTATAAGAAGTGTTTTAATTTTTATGTT
TATTAAAGGGGGACATCATC

Downstream 100 bases:

>100_bases
AGTATCGACGTGTGTAAAACTGGTTGTTGTTGATTTATGTTCAAGGTGAACGATACCAGTTTTAAAAAATATACGTGGAT
TTTTGTAAAGATGACAGCCG

Product: multidrug resistance protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MNQIHRPTVVALLLAGSFIAILNQTLMITAIPPIIIEMGITANSAQWLTTVFMLVNGIMIPVSAFLIERFTTRQLFMSSM
GIFAIGTLVAGVAPVFEMLLVGRVIQSIGAGVMLPLMTTVFLLIFPINRRGSVMGLIGLVISFAPAIGPALSGWVTGHFS
WRYLFFIIFPIAVIDMIIAYFALKNVTEVKKTKLDIPSVILSSFGFGGILYGVTNAGNYGWGASITLITLAIGVISLTLF
ILRQLKLTHPMLEFRVFKYAIFPFSVFIGSITFMGLIGTETLIPLFMQNMREFSAFQAGMAMLPGALVTGFLAPIIGRMF
DRYGGKWIVLPGVVIITLATVPFIFIDTETTFAFITTLYAVRMLGLALIMMPIQTAALNQLPNNLIPHGAAMDGTMRMTA
ASVGTAVLVTVMTSVESMAENQVARPDILGVNVSFSVIAVLGLCTIIAYFFIKFDPSPAKIAKMEEDKSN

Sequences:

>Translated_470_residues
MNQIHRPTVVALLLAGSFIAILNQTLMITAIPPIIIEMGITANSAQWLTTVFMLVNGIMIPVSAFLIERFTTRQLFMSSM
GIFAIGTLVAGVAPVFEMLLVGRVIQSIGAGVMLPLMTTVFLLIFPINRRGSVMGLIGLVISFAPAIGPALSGWVTGHFS
WRYLFFIIFPIAVIDMIIAYFALKNVTEVKKTKLDIPSVILSSFGFGGILYGVTNAGNYGWGASITLITLAIGVISLTLF
ILRQLKLTHPMLEFRVFKYAIFPFSVFIGSITFMGLIGTETLIPLFMQNMREFSAFQAGMAMLPGALVTGFLAPIIGRMF
DRYGGKWIVLPGVVIITLATVPFIFIDTETTFAFITTLYAVRMLGLALIMMPIQTAALNQLPNNLIPHGAAMDGTMRMTA
ASVGTAVLVTVMTSVESMAENQVARPDILGVNVSFSVIAVLGLCTIIAYFFIKFDPSPAKIAKMEEDKSN
>Mature_470_residues
MNQIHRPTVVALLLAGSFIAILNQTLMITAIPPIIIEMGITANSAQWLTTVFMLVNGIMIPVSAFLIERFTTRQLFMSSM
GIFAIGTLVAGVAPVFEMLLVGRVIQSIGAGVMLPLMTTVFLLIFPINRRGSVMGLIGLVISFAPAIGPALSGWVTGHFS
WRYLFFIIFPIAVIDMIIAYFALKNVTEVKKTKLDIPSVILSSFGFGGILYGVTNAGNYGWGASITLITLAIGVISLTLF
ILRQLKLTHPMLEFRVFKYAIFPFSVFIGSITFMGLIGTETLIPLFMQNMREFSAFQAGMAMLPGALVTGFLAPIIGRMF
DRYGGKWIVLPGVVIITLATVPFIFIDTETTFAFITTLYAVRMLGLALIMMPIQTAALNQLPNNLIPHGAAMDGTMRMTA
ASVGTAVLVTVMTSVESMAENQVARPDILGVNVSFSVIAVLGLCTIIAYFFIKFDPSPAKIAKMEEDKSN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1788710, Length=427, Percent_Identity=26.463700234192, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1789042, Length=422, Percent_Identity=26.7772511848341, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI87081983, Length=402, Percent_Identity=23.134328358209, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1790195, Length=460, Percent_Identity=24.3478260869565, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788392, Length=397, Percent_Identity=22.4181360201511, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6325455, Length=228, Percent_Identity=27.6315789473684, Blast_Score=76, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6319770, Length=328, Percent_Identity=23.780487804878, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50987; Mature: 50987

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQIHRPTVVALLLAGSFIAILNQTLMITAIPPIIIEMGITANSAQWLTTVFMLVNGIMI
CCCCCHHHHHHHHHHHHHHHHHCCHHHEEECCHHHHEECCCCCCHHHHHHHHHHHCCHHH
PVSAFLIERFTTRQLFMSSMGIFAIGTLVAGVAPVFEMLLVGRVIQSIGAGVMLPLMTTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FLLIFPINRRGSVMGLIGLVISFAPAIGPALSGWVTGHFSWRYLFFIIFPIAVIDMIIAY
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
FALKNVTEVKKTKLDIPSVILSSFGFGGILYGVTNAGNYGWGASITLITLAIGVISLTLF
HHHHHHHHHHHHHCCHHHHHHHCCCCCHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
ILRQLKLTHPMLEFRVFKYAIFPFSVFIGSITFMGLIGTETLIPLFMQNMREFSAFQAGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLPGALVTGFLAPIIGRMFDRYGGKWIVLPGVVIITLATVPFIFIDTETTFAFITTLYA
HHCCHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHCEEEEECCHHHHHHHHHHH
VRMLGLALIMMPIQTAALNQLPNNLIPHGAAMDGTMRMTAASVGTAVLVTVMTSVESMAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NQVARPDILGVNVSFSVIAVLGLCTIIAYFFIKFDPSPAKIAKMEEDKSN
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHEECCCHHHHHHCCCCCCC
>Mature Secondary Structure
MNQIHRPTVVALLLAGSFIAILNQTLMITAIPPIIIEMGITANSAQWLTTVFMLVNGIMI
CCCCCHHHHHHHHHHHHHHHHHCCHHHEEECCHHHHEECCCCCCHHHHHHHHHHHCCHHH
PVSAFLIERFTTRQLFMSSMGIFAIGTLVAGVAPVFEMLLVGRVIQSIGAGVMLPLMTTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FLLIFPINRRGSVMGLIGLVISFAPAIGPALSGWVTGHFSWRYLFFIIFPIAVIDMIIAY
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
FALKNVTEVKKTKLDIPSVILSSFGFGGILYGVTNAGNYGWGASITLITLAIGVISLTLF
HHHHHHHHHHHHHCCHHHHHHHCCCCCHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
ILRQLKLTHPMLEFRVFKYAIFPFSVFIGSITFMGLIGTETLIPLFMQNMREFSAFQAGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLPGALVTGFLAPIIGRMFDRYGGKWIVLPGVVIITLATVPFIFIDTETTFAFITTLYA
HHCCHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHCEEEEECCHHHHHHHHHHH
VRMLGLALIMMPIQTAALNQLPNNLIPHGAAMDGTMRMTAASVGTAVLVTVMTSVESMAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NQVARPDILGVNVSFSVIAVLGLCTIIAYFFIKFDPSPAKIAKMEEDKSN
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHEECCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]