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The map label for this gene is fhuG [H]

Identifier: 23097908

GI number: 23097908

Start: 479825

End: 480847

Strand: Direct

Name: fhuG [H]

Synonym: OB0453

Alternate gene names: 23097908

Gene position: 479825-480847 (Clockwise)

Preceding gene: 23097907

Following gene: 23097910

Centisome position: 13.22

GC content: 37.15

Gene sequence:

>1023_bases
ATGAATGAATTAGAACAACTGAAGTGGAAACGTTTTTGGACGATTAGTGGAATATTAATTGTATTAATGATTGGTTTTGC
TTTTCTTAGTTTAAATATGGGGGTAATCTCTATATCCCCAAAAGAGGTAATTCAAACATTATTCCAAAATGGTACGGATC
AACAAGAATTGGTGTTATTTAATTTTCGATTACCCGGGATTATTCTTGCATTATTAATTGGAGCTGGATTAGCAGTTTCT
GGAGCTATTATGCAAGGGTTTACCCAAAATGGATTAGCCGATCCTGGTATCCTCGGAATCAATACAGGTGCAGGATTTGC
AATTGTATTATTCTTATTTTTCTTTCAAGGTGTTATACCAAGTTCAAGCCCGCTATCTATTTTTGCCATGCCGTTTGTTG
CTTTAATAGGGGCATTAACAGCTGCAGCAATTATTTATGCACTAGCTTGGAAAAAAGGTGTAACAGCTATTCGTCTCGTG
CTAGTTGGAATTGGTGTGAATGCCGCTTTTAGTGCATTGTTGACCATTATGCAGTTGAAAATGGATCCACAGAACTTTAG
ACAAGTAACCATATGGCTGTCGGGTGATATATGGAATGCGAATTGGAACTTTGTATTTGCTTTGCTACCATGGATGCTTA
TACTCATTCCAGTTGCAATTAAAAAGTCAAAGTCTCTTAATGTGTTCAATTTAGGAGATGATGTAGCTTCTGGTTTAGGT
GTGAGAGTGGAAAAAGAAAGAGGATTACTACTATTTATTGCTGTTGCGTTAGCAGGAGCTTCCGTAGCGGCAGGTGGGGC
AATTGCATTCTTAGGACTGGTAGTACCTCATATTGTCAGAAAGATAGTCGGGCCTATGCATCAATTTGTAATTCCTATAT
CAGCTTTACTTGGTGCAGTTTTATTAATGGTAGCTGACATAATTGGAAGTAATTTATTAGCACCGAGCACCATCCCCGTT
GGTATTGTAGTTTCGATAGTAAGTACACCATACTTTATCTATTTATTAATGAAAACAAAGTAG

Upstream 100 bases:

>100_bases
TGATTAATGCACCGTTTGAAACGCCGGTTGGTGCAATCACATCAATCATTGGTGTGCCATTCTTCCTCTACTTAGCAAGA
GGTAGTGGAGGTGACAAAAA

Downstream 100 bases:

>100_bases
GATAAATTAAAGAGAAGTTAGTTAATCTCTATCTTGCTTTTTATAGCAGATAGCAGAAATATAACTAGAAAAGTTAAAGG
TCAGATGCGAAAAACGCCTC

Product: ferrichrome ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MNELEQLKWKRFWTISGILIVLMIGFAFLSLNMGVISISPKEVIQTLFQNGTDQQELVLFNFRLPGIILALLIGAGLAVS
GAIMQGFTQNGLADPGILGINTGAGFAIVLFLFFFQGVIPSSSPLSIFAMPFVALIGALTAAAIIYALAWKKGVTAIRLV
LVGIGVNAAFSALLTIMQLKMDPQNFRQVTIWLSGDIWNANWNFVFALLPWMLILIPVAIKKSKSLNVFNLGDDVASGLG
VRVEKERGLLLFIAVALAGASVAAGGAIAFLGLVVPHIVRKIVGPMHQFVIPISALLGAVLLMVADIIGSNLLAPSTIPV
GIVVSIVSTPYFIYLLMKTK

Sequences:

>Translated_340_residues
MNELEQLKWKRFWTISGILIVLMIGFAFLSLNMGVISISPKEVIQTLFQNGTDQQELVLFNFRLPGIILALLIGAGLAVS
GAIMQGFTQNGLADPGILGINTGAGFAIVLFLFFFQGVIPSSSPLSIFAMPFVALIGALTAAAIIYALAWKKGVTAIRLV
LVGIGVNAAFSALLTIMQLKMDPQNFRQVTIWLSGDIWNANWNFVFALLPWMLILIPVAIKKSKSLNVFNLGDDVASGLG
VRVEKERGLLLFIAVALAGASVAAGGAIAFLGLVVPHIVRKIVGPMHQFVIPISALLGAVLLMVADIIGSNLLAPSTIPV
GIVVSIVSTPYFIYLLMKTK
>Mature_340_residues
MNELEQLKWKRFWTISGILIVLMIGFAFLSLNMGVISISPKEVIQTLFQNGTDQQELVLFNFRLPGIILALLIGAGLAVS
GAIMQGFTQNGLADPGILGINTGAGFAIVLFLFFFQGVIPSSSPLSIFAMPFVALIGALTAAAIIYALAWKKGVTAIRLV
LVGIGVNAAFSALLTIMQLKMDPQNFRQVTIWLSGDIWNANWNFVFALLPWMLILIPVAIKKSKSLNVFNLGDDVASGLG
VRVEKERGLLLFIAVALAGASVAAGGAIAFLGLVVPHIVRKIVGPMHQFVIPISALLGAVLLMVADIIGSNLLAPSTIPV
GIVVSIVSTPYFIYLLMKTK

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=316, Percent_Identity=37.3417721518987, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1788004, Length=290, Percent_Identity=34.8275862068965, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786804, Length=310, Percent_Identity=31.6129032258064, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790741, Length=306, Percent_Identity=31.6993464052288, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786347, Length=287, Percent_Identity=34.8432055749129, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786805, Length=311, Percent_Identity=33.1189710610932, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36315; Mature: 36315

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELEQLKWKRFWTISGILIVLMIGFAFLSLNMGVISISPKEVIQTLFQNGTDQQELVLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHCCCCCCEEEEE
NFRLPGIILALLIGAGLAVSGAIMQGFTQNGLADPGILGINTGAGFAIVLFLFFFQGVIP
ECCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCC
SSSPLSIFAMPFVALIGALTAAAIIYALAWKKGVTAIRLVLVGIGVNAAFSALLTIMQLK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
MDPQNFRQVTIWLSGDIWNANWNFVFALLPWMLILIPVAIKKSKSLNVFNLGDDVASGLG
CCCCCCEEEEEEEECCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHCCCC
VRVEKERGLLLFIAVALAGASVAAGGAIAFLGLVVPHIVRKIVGPMHQFVIPISALLGAV
EEEECCCCCHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMVADIIGSNLLAPSTIPVGIVVSIVSTPYFIYLLMKTK
HHHHHHHHCCCCCCCCCCCHHHHHHHHHCCEEEEEEEECC
>Mature Secondary Structure
MNELEQLKWKRFWTISGILIVLMIGFAFLSLNMGVISISPKEVIQTLFQNGTDQQELVLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHCCCCCCEEEEE
NFRLPGIILALLIGAGLAVSGAIMQGFTQNGLADPGILGINTGAGFAIVLFLFFFQGVIP
ECCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCC
SSSPLSIFAMPFVALIGALTAAAIIYALAWKKGVTAIRLVLVGIGVNAAFSALLTIMQLK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
MDPQNFRQVTIWLSGDIWNANWNFVFALLPWMLILIPVAIKKSKSLNVFNLGDDVASGLG
CCCCCCEEEEEEEECCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHCCCC
VRVEKERGLLLFIAVALAGASVAAGGAIAFLGLVVPHIVRKIVGPMHQFVIPISALLGAV
EEEECCCCCHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMVADIIGSNLLAPSTIPVGIVVSIVSTPYFIYLLMKTK
HHHHHHHHCCCCCCCCCCCHHHHHHHHHCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]