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The map label for this gene is fhuB [H]

Identifier: 23097907

GI number: 23097907

Start: 478815

End: 479828

Strand: Direct

Name: fhuB [H]

Synonym: OB0452

Alternate gene names: 23097907

Gene position: 478815-479828 (Clockwise)

Preceding gene: 23097898

Following gene: 23097908

Centisome position: 13.19

GC content: 39.15

Gene sequence:

>1014_bases
ATGAAAACATTCACAAAATCTCCCTTTTCTAAATTAGGTTTAAACATTATTGGTTTATGTCTAGTTGTTTTTTCGATGGG
GATATCTATTTCTTATGGTGCCACAAATATAGACTTACATACTGTTTGGGATGCCGTATTACATTTTAATCCAGAAAATC
AATCCCACCAAGTTATTCAGGAGTTACGCATTCCTAGAGCGTTGTCTGCCGTTTTAGTTGGTGCATTTCTAGCTGTTTCT
GGAGCAGTCATGCAGGGGATGACACGAAATCCATTAGCTTCTCCTTCTATTATGGGTGTGACGGATGGTGCTGCATTTGC
GCTAGTTATTATGATGGCATTTTTCCCGTCTGTTTCAAGTGGAGGATTAACGCTAGGATCGTTTATTGGGGCAGGCGTAG
CTGTTACGCTAGTATTTTTAGTCGGATCGTTCTCAAGTAGTGGACTTACTCCAGTGAAATTAGCTTTAGCAGGTGTAGCT
ATTGGTACACTTTTACGGTCTTTATCATCCGTAATTTCATTGCATTTTCAACTGGAAAAAGATATTGGTTTTTGGCTTGC
TGGTGGATTGGATGGGGCCAATTGGGGATCTGTTCAACTCTTAGTCATGATTGGGATTTTCGGAATGCTGATTGCTCTAT
CAATTTCAAAATCTATCACAGTGCTAAGTCTAGGTGATGATTTATCAACAGGTCTAGGTCAAAATAATACGATGATTAAG
ATCATGGGGATCATTTCCGTATTATTATTAACTGGGGTGGCAGTATCAATAGCTGGATCTGTTGGTTTTATCGGGTTAAT
TATTCCTCATATCACAAGGTTTATTATTGGCACAGACTATCGTTGGATTATTCCTACAACAGCTGTGTTTGGTTCGCTTC
TTTTAGTAAATGCGGATTTAATAGCAAGAATGATTAATGCACCGTTTGAAACGCCGGTTGGTGCAATCACATCAATCATT
GGTGTGCCATTCTTCCTCTACTTAGCAAGAGGTAGTGGAGGTGACAAAAAATGA

Upstream 100 bases:

>100_bases
TTGTTGGCAAACCGTCTATTCGAATCTTCCTTAATATATAATTAAGGAGACATTAAACACAATGATTGAAGATGTATAAT
CTTGTATAGGAGTCTTTTTT

Downstream 100 bases:

>100_bases
ATGAATTAGAACAACTGAAGTGGAAACGTTTTTGGACGATTAGTGGAATATTAATTGTATTAATGATTGGTTTTGCTTTT
CTTAGTTTAAATATGGGGGT

Product: ferrichrome ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein B; Ferrichrome transport system permease protein fhuB; Iron(III)-hydroxamate import system permease protein fhuB [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKTFTKSPFSKLGLNIIGLCLVVFSMGISISYGATNIDLHTVWDAVLHFNPENQSHQVIQELRIPRALSAVLVGAFLAVS
GAVMQGMTRNPLASPSIMGVTDGAAFALVIMMAFFPSVSSGGLTLGSFIGAGVAVTLVFLVGSFSSSGLTPVKLALAGVA
IGTLLRSLSSVISLHFQLEKDIGFWLAGGLDGANWGSVQLLVMIGIFGMLIALSISKSITVLSLGDDLSTGLGQNNTMIK
IMGIISVLLLTGVAVSIAGSVGFIGLIIPHITRFIIGTDYRWIIPTTAVFGSLLLVNADLIARMINAPFETPVGAITSII
GVPFFLYLARGSGGDKK

Sequences:

>Translated_337_residues
MKTFTKSPFSKLGLNIIGLCLVVFSMGISISYGATNIDLHTVWDAVLHFNPENQSHQVIQELRIPRALSAVLVGAFLAVS
GAVMQGMTRNPLASPSIMGVTDGAAFALVIMMAFFPSVSSGGLTLGSFIGAGVAVTLVFLVGSFSSSGLTPVKLALAGVA
IGTLLRSLSSVISLHFQLEKDIGFWLAGGLDGANWGSVQLLVMIGIFGMLIALSISKSITVLSLGDDLSTGLGQNNTMIK
IMGIISVLLLTGVAVSIAGSVGFIGLIIPHITRFIIGTDYRWIIPTTAVFGSLLLVNADLIARMINAPFETPVGAITSII
GVPFFLYLARGSGGDKK
>Mature_337_residues
MKTFTKSPFSKLGLNIIGLCLVVFSMGISISYGATNIDLHTVWDAVLHFNPENQSHQVIQELRIPRALSAVLVGAFLAVS
GAVMQGMTRNPLASPSIMGVTDGAAFALVIMMAFFPSVSSGGLTLGSFIGAGVAVTLVFLVGSFSSSGLTPVKLALAGVA
IGTLLRSLSSVISLHFQLEKDIGFWLAGGLDGANWGSVQLLVMIGIFGMLIALSISKSITVLSLGDDLSTGLGQNNTMIK
IMGIISVLLLTGVAVSIAGSVGFIGLIIPHITRFIIGTDYRWIIPTTAVFGSLLLVNADLIARMINAPFETPVGAITSII
GVPFFLYLARGSGGDKK

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=336, Percent_Identity=34.2261904761905, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1790740, Length=290, Percent_Identity=36.551724137931, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1786805, Length=305, Percent_Identity=36.0655737704918, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1788004, Length=290, Percent_Identity=33.448275862069, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1786347, Length=276, Percent_Identity=31.8840579710145, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1786804, Length=316, Percent_Identity=31.0126582278481, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35115; Mature: 35115

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFTKSPFSKLGLNIIGLCLVVFSMGISISYGATNIDLHTVWDAVLHFNPENQSHQVIQ
CCCCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHH
ELRIPRALSAVLVGAFLAVSGAVMQGMTRNPLASPSIMGVTDGAAFALVIMMAFFPSVSS
HHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCC
GGLTLGSFIGAGVAVTLVFLVGSFSSSGLTPVKLALAGVAIGTLLRSLSSVISLHFQLEK
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
DIGFWLAGGLDGANWGSVQLLVMIGIFGMLIALSISKSITVLSLGDDLSTGLGQNNTMIK
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCCCCHHH
IMGIISVLLLTGVAVSIAGSVGFIGLIIPHITRFIIGTDYRWIIPTTAVFGSLLLVNADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHH
IARMINAPFETPVGAITSIIGVPFFLYLARGSGGDKK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKTFTKSPFSKLGLNIIGLCLVVFSMGISISYGATNIDLHTVWDAVLHFNPENQSHQVIQ
CCCCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHH
ELRIPRALSAVLVGAFLAVSGAVMQGMTRNPLASPSIMGVTDGAAFALVIMMAFFPSVSS
HHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCC
GGLTLGSFIGAGVAVTLVFLVGSFSSSGLTPVKLALAGVAIGTLLRSLSSVISLHFQLEK
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
DIGFWLAGGLDGANWGSVQLLVMIGIFGMLIALSISKSITVLSLGDDLSTGLGQNNTMIK
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCCCCHHH
IMGIISVLLLTGVAVSIAGSVGFIGLIIPHITRFIIGTDYRWIIPTTAVFGSLLLVNADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHH
IARMINAPFETPVGAITSIIGVPFFLYLARGSGGDKK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377; 8388528 [H]