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The map label for this gene is mta [H]

Identifier: 23097837

GI number: 23097837

Start: 406314

End: 407078

Strand: Direct

Name: mta [H]

Synonym: OB0382

Alternate gene names: 23097837

Gene position: 406314-407078 (Clockwise)

Preceding gene: 23097834

Following gene: 23097838

Centisome position: 11.19

GC content: 35.69

Gene sequence:

>765_bases
GTGGATTATACCGTAAAGCAAATAGCAGACTTATCAGGTGTTAGTGCACGAACACTTCGATATTATGATCAAATTAATCT
GCTTAAGCCAAAGATGGTAAATGATTCTGGATATCGCATTTATGGTGAGGAAGAAATTAATCGTCTGCAGCAAATACTCC
TTTATCGATCCATGGGGATGAAGTTGGAGCAAATTCAATCTGTTCTCGATGATTCTACATTTGATATCCATATTGCTTTG
GAAGAACACCGTAAACAACTACTGGCAAAACGGAAGCAAATTGACCACTTATTACTGACTGTCGATAAGACGATACGTTA
TCAAAAAGGAGAATTAAATATGTCGAATAACGAGAAGTTCGAAGGGTTTAAAAAAGAACAATTGGAAGAAAATGAGAAGA
TGTTTGGTGATGAAATCCGTCAAAAATATGGAGAAGAGGCAGTAAATGCTTCTAATCAACAATGGATGAATATGAGTGAG
AAAGATTTTAAGAAGATGCAGGAAATAGAAGATGAATTGTTTATGACATTAGACCAATTAGATCAATCAAAAGATTTAGA
TTCCAAAGAAGCACAGCAAGCGTTTGACCTTCATAAGAATTGGTTATTGTATAGTTGGTCAGAGTATTCTGCTGAAGCAC
ACAAAGGGTTAGCGGAAATGTATGCAGCAGATGATCGTTTTAGAAAGTATTATAACGACAAAGCGGGTAAGGAAATTGTA
GATTTACTTCGCGACGTAATAGTGAAGTATGCGAACCAACAATAA

Upstream 100 bases:

>100_bases
TTCTGTTTACCCGATGAACCTTTTCTTGAAACAACCAAAAAAATGTATTGACCTATACGCAGCGTAAACCTTTAAACTGA
AATTATCAGGAGGTGATGAA

Downstream 100 bases:

>100_bases
TTGATTATAAAGAGCCTCTAGTCATTGGTACTAGAGGCTTATAAAATTTTTAGAAACTTTTTTAGCGATGAATCGTAAAA
TAGTTGATAATTCTTTTAAT

Product: transcriptional activator of multidrug-efflux transporters

Products: NA

Alternate protein names: Multidrug transporter activation protein [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MDYTVKQIADLSGVSARTLRYYDQINLLKPKMVNDSGYRIYGEEEINRLQQILLYRSMGMKLEQIQSVLDDSTFDIHIAL
EEHRKQLLAKRKQIDHLLLTVDKTIRYQKGELNMSNNEKFEGFKKEQLEENEKMFGDEIRQKYGEEAVNASNQQWMNMSE
KDFKKMQEIEDELFMTLDQLDQSKDLDSKEAQQAFDLHKNWLLYSWSEYSAEAHKGLAEMYAADDRFRKYYNDKAGKEIV
DLLRDVIVKYANQQ

Sequences:

>Translated_254_residues
MDYTVKQIADLSGVSARTLRYYDQINLLKPKMVNDSGYRIYGEEEINRLQQILLYRSMGMKLEQIQSVLDDSTFDIHIAL
EEHRKQLLAKRKQIDHLLLTVDKTIRYQKGELNMSNNEKFEGFKKEQLEENEKMFGDEIRQKYGEEAVNASNQQWMNMSE
KDFKKMQEIEDELFMTLDQLDQSKDLDSKEAQQAFDLHKNWLLYSWSEYSAEAHKGLAEMYAADDRFRKYYNDKAGKEIV
DLLRDVIVKYANQQ
>Mature_254_residues
MDYTVKQIADLSGVSARTLRYYDQINLLKPKMVNDSGYRIYGEEEINRLQQILLYRSMGMKLEQIQSVLDDSTFDIHIAL
EEHRKQLLAKRKQIDHLLLTVDKTIRYQKGELNMSNNEKFEGFKKEQLEENEKMFGDEIRQKYGEEAVNASNQQWMNMSE
KDFKKMQEIEDELFMTLDQLDQSKDLDSKEAQQAFDLHKNWLLYSWSEYSAEAHKGLAEMYAADDRFRKYYNDKAGKEIV
DLLRDVIVKYANQQ

Specific function: Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself, ydfK and ymfE [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR012925
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; PF07739 TipAS [H]

EC number: NA

Molecular weight: Translated: 30143; Mature: 30143

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYTVKQIADLSGVSARTLRYYDQINLLKPKMVNDSGYRIYGEEEINRLQQILLYRSMGM
CCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCEEECHHHHHHHHHHHHHHHHCC
KLEQIQSVLDDSTFDIHIALEEHRKQLLAKRKQIDHLLLTVDKTIRYQKGELNMSNNEKF
CHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
EGFKKEQLEENEKMFGDEIRQKYGEEAVNASNQQWMNMSEKDFKKMQEIEDELFMTLDQL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DQSKDLDSKEAQQAFDLHKNWLLYSWSEYSAEAHKGLAEMYAADDRFRKYYNDKAGKEIV
HCCCCCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
DLLRDVIVKYANQQ
HHHHHHHHHHCCCC
>Mature Secondary Structure
MDYTVKQIADLSGVSARTLRYYDQINLLKPKMVNDSGYRIYGEEEINRLQQILLYRSMGM
CCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCEEECHHHHHHHHHHHHHHHHCC
KLEQIQSVLDDSTFDIHIALEEHRKQLLAKRKQIDHLLLTVDKTIRYQKGELNMSNNEKF
CHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
EGFKKEQLEENEKMFGDEIRQKYGEEAVNASNQQWMNMSEKDFKKMQEIEDELFMTLDQL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DQSKDLDSKEAQQAFDLHKNWLLYSWSEYSAEAHKGLAEMYAADDRFRKYYNDKAGKEIV
HCCCCCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
DLLRDVIVKYANQQ
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9150240; 9384377 [H]