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The map label for this gene is yycF [H]

Identifier: 23097812

GI number: 23097812

Start: 376111

End: 376881

Strand: Direct

Name: yycF [H]

Synonym: OB0357

Alternate gene names: 23097812

Gene position: 376111-376881 (Clockwise)

Preceding gene: 23097811

Following gene: 23097813

Centisome position: 10.36

GC content: 35.8

Gene sequence:

>771_bases
ATGAAAAAATGTAGAATAAAAGAAATGTTAGAAACCTCAAAGGTGGATGAGTGTAATATGAATATATTAATTGTGGAAGA
CGATAAGACGATTGCGACAGGATTAGAGTACTCGTTAAAACAAGAGGGTTATGATGTGGTAGTTTGTCATAAAGTTCAAG
AAGCGCAGAGGAAGATAAATAATGATTTAGATGATATATCTCTTTGTTTGTTCGATTTGTCATTACCGGATGGCAGTGGG
TATGAGCTTTGTGAAATGGTGAAGCGAAAAGCGGATATTCCGGTAATTTTTCTTACGGTCGTAGATGATGAGGTTAATGT
TGTGATGGGGCTTGATATGGGTGCAGATGATTACATAACGAAGCCCTTTCGAATTCGCGAATTAATCTCTCGAATAAAAA
CAGTTCTCAGGCGCTATGAAAAAAGCAAACCAAATAAAGAGCAATTATCCAGCGTTATTTCTATCGGATCGATTAACATT
CATACTCTCGAGGGGAAAGTTTATAAAGAGACAGAAGAAATACTATTAACAGCCTTGGAATATCGTTTATTAATGATTTT
TGTGAACCATCGCGGACAAGTTTTATCTAGAAAACAATTGCTTCAGTTAATATGGGATATAGCTGGTGACTTTGTGAACG
ATAATACATTAACTGTATATATAAAGCGGCTAAGGAAAAAGATTGAAGAGGATGCACAACATCCAACAGTAATTGAGACT
GTTCGTGGGATGGGATATAGGATGGTAGATACACATGATAAGAAACAATGA

Upstream 100 bases:

>100_bases
TCTGAAGAAGAAAAGGTAACTCATAGGGCCCGAAATCCAGAAGGCTAGTGAAAATAGTCACTCATTGAAGTTAGCGATTG
TATTGAGGATGATAATTAAC

Downstream 100 bases:

>100_bases
GGTTCGGAGATATTTATTTTTTGCAATTACCATTCTCATAATTAGTACGGTTTCGATAGCATTTATTTCGTCTGTTGCTG
CTGGAATTGTTTTTGTATCG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKKCRIKEMLETSKVDECNMNILIVEDDKTIATGLEYSLKQEGYDVVVCHKVQEAQRKINNDLDDISLCLFDLSLPDGSG
YELCEMVKRKADIPVIFLTVVDDEVNVVMGLDMGADDYITKPFRIRELISRIKTVLRRYEKSKPNKEQLSSVISIGSINI
HTLEGKVYKETEEILLTALEYRLLMIFVNHRGQVLSRKQLLQLIWDIAGDFVNDNTLTVYIKRLRKKIEEDAQHPTVIET
VRGMGYRMVDTHDKKQ

Sequences:

>Translated_256_residues
MKKCRIKEMLETSKVDECNMNILIVEDDKTIATGLEYSLKQEGYDVVVCHKVQEAQRKINNDLDDISLCLFDLSLPDGSG
YELCEMVKRKADIPVIFLTVVDDEVNVVMGLDMGADDYITKPFRIRELISRIKTVLRRYEKSKPNKEQLSSVISIGSINI
HTLEGKVYKETEEILLTALEYRLLMIFVNHRGQVLSRKQLLQLIWDIAGDFVNDNTLTVYIKRLRKKIEEDAQHPTVIET
VRGMGYRMVDTHDKKQ
>Mature_256_residues
MKKCRIKEMLETSKVDECNMNILIVEDDKTIATGLEYSLKQEGYDVVVCHKVQEAQRKINNDLDDISLCLFDLSLPDGSG
YELCEMVKRKADIPVIFLTVVDDEVNVVMGLDMGADDYITKPFRIRELISRIKTVLRRYEKSKPNKEQLSSVISIGSINI
HTLEGKVYKETEEILLTALEYRLLMIFVNHRGQVLSRKQLLQLIWDIAGDFVNDNTLTVYIKRLRKKIEEDAQHPTVIET
VRGMGYRMVDTHDKKQ

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=36.9565217391304, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=36.5217391304348, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789809, Length=238, Percent_Identity=33.6134453781513, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=31.8777292576419, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=32.9004329004329, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788394, Length=242, Percent_Identity=34.297520661157, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=32.4675324675325, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=31.6017316017316, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=29.9145299145299, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=33.8983050847458, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1790552, Length=235, Percent_Identity=35.3191489361702, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=33.9130434782609, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789402, Length=232, Percent_Identity=30.1724137931034, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=30.6034482758621, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29571; Mature: 29571

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKCRIKEMLETSKVDECNMNILIVEDDKTIATGLEYSLKQEGYDVVVCHKVQEAQRKIN
CCCCHHHHHHHHCCCCCCCCEEEEEECCCHHHHCCHHHHHHCCCCEEEEHHHHHHHHHHC
NDLDDISLCLFDLSLPDGSGYELCEMVKRKADIPVIFLTVVDDEVNVVMGLDMGADDYIT
CCHHHHEEHEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCC
KPFRIRELISRIKTVLRRYEKSKPNKEQLSSVISIGSINIHTLEGKVYKETEEILLTALE
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHH
YRLLMIFVNHRGQVLSRKQLLQLIWDIAGDFVNDNTLTVYIKRLRKKIEEDAQHPTVIET
HHHHHHEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
VRGMGYRMVDTHDKKQ
HHCCCEEEECCCCCCC
>Mature Secondary Structure
MKKCRIKEMLETSKVDECNMNILIVEDDKTIATGLEYSLKQEGYDVVVCHKVQEAQRKIN
CCCCHHHHHHHHCCCCCCCCEEEEEECCCHHHHCCHHHHHHCCCCEEEEHHHHHHHHHHC
NDLDDISLCLFDLSLPDGSGYELCEMVKRKADIPVIFLTVVDDEVNVVMGLDMGADDYIT
CCHHHHEEHEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCC
KPFRIRELISRIKTVLRRYEKSKPNKEQLSSVISIGSINIHTLEGKVYKETEEILLTALE
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHH
YRLLMIFVNHRGQVLSRKQLLQLIWDIAGDFVNDNTLTVYIKRLRKKIEEDAQHPTVIET
HHHHHHEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
VRGMGYRMVDTHDKKQ
HHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]