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The map label for this gene is yehU [H]

Identifier: 22127756

GI number: 22127756

Start: 4334309

End: 4336006

Strand: Reverse

Name: yehU [H]

Synonym: y3885

Alternate gene names: 22127756

Gene position: 4336006-4334309 (Counterclockwise)

Preceding gene: 161484730

Following gene: 22127754

Centisome position: 94.25

GC content: 48.35

Gene sequence:

>1698_bases
ATGGGCATTAGCCAAACAGAACTGATCTTTTCCCTTTTACAACAGATGTGTGTGTATTTGGTTATTGCCTATCTGCTGAG
TAAAACACCGCTTTTTATCCCCTTGATGCAAGTTACTATCAGGTTGCCCCATAAACTGGTGTGCTATCTCACCTTTTCCA
TGTTTTGCATTATGGGCACCTACTTTGGTCTTAACATTGATGATTCTATCGCGAATACTCGTGCTATCGGCGCAGTCTTG
GGTGGAATGCTAGGGGGGCCATCGGTCGGGTTTCTGGTAGGGCTAACCGGAGGCCTGCATCGTTATTCAATGGGGGGGAT
GACCGCAACCGCCTGTATGTTATCAACCATTGCTGAAGGGTTATTGGGCGGCCTTCTCCACCTTTATCTGACACGTAAAA
ACCGCCTCGATTTATTGTTTCAGCCACTGGTGGTCGCGGGCATTACACTGGTAGCCGAAGTGCTACAAATGATGATTATT
CTGGCCGTCGCCCGCCCCTTCAATGAAGCGGTCGAATTGGTTGAAAATATTGCCTTGCCGATGATGATCACCAATACCAT
TGGTGCCGCCATGTTTATGCGTATCTTATTAGACCGCCGGGCCATTTTCGAAAAATACACCACGGCATTTTCTGCCAAGG
CGCTACAAATTGCTGCACGGGCGGAGGGGCTACTGCGCCATGGCTTTGACCAGCAGAACAGTATGCGGGTGGCTCGTATC
TTGTATGAGGAGTTGGGTGTGGGCGCAGTAGCCATTACTGATCGCGAAAAATTACTGGCCTTTATCGGTAGCGGTGCCGA
CCACCATCAGGTGGGCAGTGCTATTACCTCCAGCCATACCCACCGCGCGATTGAACTCAATCAGGTGGTGTATGCCGACG
GCAATGCCGTGCCTTATACCTGCTCAATTTCACCCACCTGTAAGCTGGGTTCAACACTGGTTATCCCTTTGCGAGGTGAA
GAGCACCGGGTGATCGGCAGTATCAAATTGTATGAGCCAAAAAGTAAATTATTCTCCAGCATTAACCGCACCTTAGGAGA
GGGTATTGCGCACTTATTGTCAGCACAGATTTTGGCGGGAGAATTCGAACAACAAAAACAATTACTGGCGCAATCTGAAA
TCAAACTGCTCCATGCACAGGTCAACCCACATTTCTTGTTTAATGCGCTCAATACCCTATCAGTGGTGATCCGCCGTAAT
CCAGATCATGCCCGCAATTTGGTGCTTTCTTTATCAACCTTTTTCCGTAAAAACCTAAAACGCAGCCATGACGTGGTCAC
GTTAAGTGATGAGATTGAACATGTGAATGCGTATCTTGAAATAGAAAAGGCACGCTTTGCTGATCGTCTGACCGTCACGG
TTTCACTACCGAATGAACTGATGGAGGCGCACTTACCCGCGTTCTCCCTGCAACCCGTGGTAGAAAATGCAATCAAACAT
GGTATCTCACAGATGTTCAGTAACGGACGGGTCACGTTGCGCGGTAAATTGGATGACAACACGTTGGTATTGGAAGTCGA
AGATAACGCCGGTTTATATCAGCCGCAGCCGGATGGCGATGGTCTGGGAATGAGTTTGGTTGATCGGCGGATTAAAGCGC
GCTATGGCAAGGAATATGGCATCACCGTCGTCAGTAACGCGGAAGTATTTACCCGTATTATTATTAAGTTACCGTTTATT
ACCGTGAGCGAGCAGTAA

Upstream 100 bases:

>100_bases
GGTGATTAACGTCTCTGGCGCAAAATACGGATACAATAGCGGCAGAAATAACGCTACCCAGAATCACTCCCTCCCAACGT
CATAACAGTGGTCATCCAAC

Downstream 100 bases:

>100_bases
GACGGTTTCATTTCGAGAGACGATCTCGTCAAAGGCGGCATATCTTTTGACGATTAGAAAACCCTATAAAAATTAATGCC
AGAGTATAACCCACCTCTGG

Product: two-component sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MGISQTELIFSLLQQMCVYLVIAYLLSKTPLFIPLMQVTIRLPHKLVCYLTFSMFCIMGTYFGLNIDDSIANTRAIGAVL
GGMLGGPSVGFLVGLTGGLHRYSMGGMTATACMLSTIAEGLLGGLLHLYLTRKNRLDLLFQPLVVAGITLVAEVLQMMII
LAVARPFNEAVELVENIALPMMITNTIGAAMFMRILLDRRAIFEKYTTAFSAKALQIAARAEGLLRHGFDQQNSMRVARI
LYEELGVGAVAITDREKLLAFIGSGADHHQVGSAITSSHTHRAIELNQVVYADGNAVPYTCSISPTCKLGSTLVIPLRGE
EHRVIGSIKLYEPKSKLFSSINRTLGEGIAHLLSAQILAGEFEQQKQLLAQSEIKLLHAQVNPHFLFNALNTLSVVIRRN
PDHARNLVLSLSTFFRKNLKRSHDVVTLSDEIEHVNAYLEIEKARFADRLTVTVSLPNELMEAHLPAFSLQPVVENAIKH
GISQMFSNGRVTLRGKLDDNTLVLEVEDNAGLYQPQPDGDGLGMSLVDRRIKARYGKEYGITVVSNAEVFTRIIIKLPFI
TVSEQ

Sequences:

>Translated_565_residues
MGISQTELIFSLLQQMCVYLVIAYLLSKTPLFIPLMQVTIRLPHKLVCYLTFSMFCIMGTYFGLNIDDSIANTRAIGAVL
GGMLGGPSVGFLVGLTGGLHRYSMGGMTATACMLSTIAEGLLGGLLHLYLTRKNRLDLLFQPLVVAGITLVAEVLQMMII
LAVARPFNEAVELVENIALPMMITNTIGAAMFMRILLDRRAIFEKYTTAFSAKALQIAARAEGLLRHGFDQQNSMRVARI
LYEELGVGAVAITDREKLLAFIGSGADHHQVGSAITSSHTHRAIELNQVVYADGNAVPYTCSISPTCKLGSTLVIPLRGE
EHRVIGSIKLYEPKSKLFSSINRTLGEGIAHLLSAQILAGEFEQQKQLLAQSEIKLLHAQVNPHFLFNALNTLSVVIRRN
PDHARNLVLSLSTFFRKNLKRSHDVVTLSDEIEHVNAYLEIEKARFADRLTVTVSLPNELMEAHLPAFSLQPVVENAIKH
GISQMFSNGRVTLRGKLDDNTLVLEVEDNAGLYQPQPDGDGLGMSLVDRRIKARYGKEYGITVVSNAEVFTRIIIKLPFI
TVSEQ
>Mature_564_residues
GISQTELIFSLLQQMCVYLVIAYLLSKTPLFIPLMQVTIRLPHKLVCYLTFSMFCIMGTYFGLNIDDSIANTRAIGAVLG
GMLGGPSVGFLVGLTGGLHRYSMGGMTATACMLSTIAEGLLGGLLHLYLTRKNRLDLLFQPLVVAGITLVAEVLQMMIIL
AVARPFNEAVELVENIALPMMITNTIGAAMFMRILLDRRAIFEKYTTAFSAKALQIAARAEGLLRHGFDQQNSMRVARIL
YEELGVGAVAITDREKLLAFIGSGADHHQVGSAITSSHTHRAIELNQVVYADGNAVPYTCSISPTCKLGSTLVIPLRGEE
HRVIGSIKLYEPKSKLFSSINRTLGEGIAHLLSAQILAGEFEQQKQLLAQSEIKLLHAQVNPHFLFNALNTLSVVIRRNP
DHARNLVLSLSTFFRKNLKRSHDVVTLSDEIEHVNAYLEIEKARFADRLTVTVSLPNELMEAHLPAFSLQPVVENAIKHG
ISQMFSNGRVTLRGKLDDNTLVLEVEDNAGLYQPQPDGDGLGMSLVDRRIKARYGKEYGITVVSNAEVFTRIIIKLPFIT
VSEQ

Specific function: Unknown

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788446, Length=552, Percent_Identity=67.7536231884058, Blast_Score=766, Evalue=0.0,
Organism=Escherichia coli, GI1788723, Length=545, Percent_Identity=28.9908256880734, Blast_Score=243, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: NA

Molecular weight: Translated: 62187; Mature: 62056

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGISQTELIFSLLQQMCVYLVIAYLLSKTPLFIPLMQVTIRLPHKLVCYLTFSMFCIMGT
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
YFGLNIDDSIANTRAIGAVLGGMLGGPSVGFLVGLTGGLHRYSMGGMTATACMLSTIAEG
HCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCHHHHCCCCHHHHHHHHHHHHHH
LLGGLLHLYLTRKNRLDLLFQPLVVAGITLVAEVLQMMIILAVARPFNEAVELVENIALP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCH
MMITNTIGAAMFMRILLDRRAIFEKYTTAFSAKALQIAARAEGLLRHGFDQQNSMRVARI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
LYEELGVGAVAITDREKLLAFIGSGADHHQVGSAITSSHTHRAIELNQVVYADGNAVPYT
HHHHHCCCEEEECCHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEECEEEEECCCCCEEE
CSISPTCKLGSTLVIPLRGEEHRVIGSIKLYEPKSKLFSSINRTLGEGIAHLLSAQILAG
ECCCCCCCCCCEEEEEECCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFEQQKQLLAQSEIKLLHAQVNPHFLFNALNTLSVVIRRNPDHARNLVLSLSTFFRKNLK
HHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHC
RSHDVVTLSDEIEHVNAYLEIEKARFADRLTVTVSLPNELMEAHLPAFSLQPVVENAIKH
CCCCEEEECHHHHHHHHHEEEHHHHCCCEEEEEEECCHHHHHHHCCCCCCCHHHHHHHHH
GISQMFSNGRVTLRGKLDDNTLVLEVEDNAGLYQPQPDGDGLGMSLVDRRIKARYGKEYG
HHHHHHCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
ITVVSNAEVFTRIIIKLPFITVSEQ
EEEEECHHHHHHHHHHCCCEEECCC
>Mature Secondary Structure 
GISQTELIFSLLQQMCVYLVIAYLLSKTPLFIPLMQVTIRLPHKLVCYLTFSMFCIMGT
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
YFGLNIDDSIANTRAIGAVLGGMLGGPSVGFLVGLTGGLHRYSMGGMTATACMLSTIAEG
HCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCHHHHCCCCHHHHHHHHHHHHHH
LLGGLLHLYLTRKNRLDLLFQPLVVAGITLVAEVLQMMIILAVARPFNEAVELVENIALP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCH
MMITNTIGAAMFMRILLDRRAIFEKYTTAFSAKALQIAARAEGLLRHGFDQQNSMRVARI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
LYEELGVGAVAITDREKLLAFIGSGADHHQVGSAITSSHTHRAIELNQVVYADGNAVPYT
HHHHHCCCEEEECCHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEECEEEEECCCCCEEE
CSISPTCKLGSTLVIPLRGEEHRVIGSIKLYEPKSKLFSSINRTLGEGIAHLLSAQILAG
ECCCCCCCCCCEEEEEECCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFEQQKQLLAQSEIKLLHAQVNPHFLFNALNTLSVVIRRNPDHARNLVLSLSTFFRKNLK
HHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHC
RSHDVVTLSDEIEHVNAYLEIEKARFADRLTVTVSLPNELMEAHLPAFSLQPVVENAIKH
CCCCEEEECHHHHHHHHHEEEHHHHCCCEEEEEEECCHHHHHHHCCCCCCCHHHHHHHHH
GISQMFSNGRVTLRGKLDDNTLVLEVEDNAGLYQPQPDGDGLGMSLVDRRIKARYGKEYG
HHHHHHCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
ITVVSNAEVFTRIIIKLPFITVSEQ
EEEEECHHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]