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The map label for this gene is prtC [H]

Identifier: 22127728

GI number: 22127728

Start: 4295303

End: 4296640

Strand: Reverse

Name: prtC [H]

Synonym: y3857

Alternate gene names: 22127728

Gene position: 4296640-4295303 (Counterclockwise)

Preceding gene: 22127729

Following gene: 22127725

Centisome position: 93.39

GC content: 42.08

Gene sequence:

>1338_bases
GTGATGTTTATGAGTTACTCCAGGGAATACAGCAATACTATAATTAAAAATGAACAGGTCATGCGTAGAGGCATTCATTA
TAAGAATGAAGTTAAAGGTGTTATAGCACCACAAATATCTAGCCGTCAGTCATGGAAAGAAAACACCATTCATAATAAAA
ATACAAACCTGACATATTCATTTAGTCGAGCCTATACATTATGGGATTATGATCGAACATTCCAACAGAACGCTTACATC
TCATTATTTAATCCAGCCCAAATCCATCAGGCAAAAATCGCGATGCAATCTTGGGCTGATGTAGCCAACATCTCCTTCAC
CGAAGCATCAGCAGACTCCTCCGCCAATATTCTATTTTTAAATTTTCAGCGCCCAAGTAATGTGGCAGGTTATGCCTATT
ATCCTAATCCAGGTAGCTTCAGCCCAATATGGATTAATTACAGTTTCAGCGATAACCAACATCCCAGCAGATTAAATGAT
GGTGGCGGAGTATTAACACATGAGATCGGCCATGCTCTGGGGTTGGGTCATTCTCATGCCCCCCATGGCTATACACAGCA
AATGAGTGTAATGAGCTATTTATCCGAACAGGGTTCAGGTGCAAATTATGGCCAACATTACTTATCCACACCACAAATGT
ACGATATCGCCGCAATCCAGTATCTGTATGGGGCCAATCTACACACCCGCACCGGTGATACCGTTTATGGCTTCAACTCG
ACGAGTTATAGAGATCATTTCACCGCCACCCACGCCAGTGATGCGTTGATTTTCTGTGTCTGGGATGCTGGCGGCAATGA
TACTTTTGACTTCTCTGGCTATAAGCAAAATCAAATGATTAATCTTAACGAACTCTGTTTTTCTGATGTTGGTGGACTAA
AAGGAAATGTGTCTATTGCAGCGGATGTTACGATTGAAAATGCCATCGGCGGCAGTGGCCATGATGATATTATCGGCAAT
CACACCAATAATATTTTGACCGGTAACGGCGGATCTGATCAACTTTGGGGTAACGGGGGCAATAATACTTTCCGCTATGC
CAGTGCCAGAGATTCAATGACCACCTCGCCCGATACTATTCATGATTTTAAATCAGGCCGTGACAAGATAGATTTGTCGC
AATTAATGCCCTCAACCGACCGTGTTATTTTTGTCGATAGATTAAGTTTTAACGGTCAAACAGAGATGGGGCAGCAATAT
AATGAAGTGGCGGACATAACTTATCTTATGATTGATTTTGACGCTCAAGTCAGCGAGTGCGATATGATGATTAAATTTAC
CGGCAGGCACCATTTCACCGCCAATGACTTTATTTTAAGTACGTCACTGACGGCATAA

Upstream 100 bases:

>100_bases
CTTTAAGATTACGCTTATTTAAAACACCTCTGTCATCATTAATATCTCCCTCGCACATTAATAGAGATCAAAATATTTTA
TTAACACTCAAAAAGAGACG

Downstream 100 bases:

>100_bases
ATATTTATATCTACTTACCCGAATCACTCATTAAAATTTCAGCGATTCGGGTGAGAAAATGCCGCTAACGCGGCGGCGTC
ACCGATGAAGGGTATATGTC

Product: metalloprotease

Products: NA

Alternate protein names: ProC [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MMFMSYSREYSNTIIKNEQVMRRGIHYKNEVKGVIAPQISSRQSWKENTIHNKNTNLTYSFSRAYTLWDYDRTFQQNAYI
SLFNPAQIHQAKIAMQSWADVANISFTEASADSSANILFLNFQRPSNVAGYAYYPNPGSFSPIWINYSFSDNQHPSRLND
GGGVLTHEIGHALGLGHSHAPHGYTQQMSVMSYLSEQGSGANYGQHYLSTPQMYDIAAIQYLYGANLHTRTGDTVYGFNS
TSYRDHFTATHASDALIFCVWDAGGNDTFDFSGYKQNQMINLNELCFSDVGGLKGNVSIAADVTIENAIGGSGHDDIIGN
HTNNILTGNGGSDQLWGNGGNNTFRYASARDSMTTSPDTIHDFKSGRDKIDLSQLMPSTDRVIFVDRLSFNGQTEMGQQY
NEVADITYLMIDFDAQVSECDMMIKFTGRHHFTANDFILSTSLTA

Sequences:

>Translated_445_residues
MMFMSYSREYSNTIIKNEQVMRRGIHYKNEVKGVIAPQISSRQSWKENTIHNKNTNLTYSFSRAYTLWDYDRTFQQNAYI
SLFNPAQIHQAKIAMQSWADVANISFTEASADSSANILFLNFQRPSNVAGYAYYPNPGSFSPIWINYSFSDNQHPSRLND
GGGVLTHEIGHALGLGHSHAPHGYTQQMSVMSYLSEQGSGANYGQHYLSTPQMYDIAAIQYLYGANLHTRTGDTVYGFNS
TSYRDHFTATHASDALIFCVWDAGGNDTFDFSGYKQNQMINLNELCFSDVGGLKGNVSIAADVTIENAIGGSGHDDIIGN
HTNNILTGNGGSDQLWGNGGNNTFRYASARDSMTTSPDTIHDFKSGRDKIDLSQLMPSTDRVIFVDRLSFNGQTEMGQQY
NEVADITYLMIDFDAQVSECDMMIKFTGRHHFTANDFILSTSLTA
>Mature_445_residues
MMFMSYSREYSNTIIKNEQVMRRGIHYKNEVKGVIAPQISSRQSWKENTIHNKNTNLTYSFSRAYTLWDYDRTFQQNAYI
SLFNPAQIHQAKIAMQSWADVANISFTEASADSSANILFLNFQRPSNVAGYAYYPNPGSFSPIWINYSFSDNQHPSRLND
GGGVLTHEIGHALGLGHSHAPHGYTQQMSVMSYLSEQGSGANYGQHYLSTPQMYDIAAIQYLYGANLHTRTGDTVYGFNS
TSYRDHFTATHASDALIFCVWDAGGNDTFDFSGYKQNQMINLNELCFSDVGGLKGNVSIAADVTIENAIGGSGHDDIIGN
HTNNILTGNGGSDQLWGNGGNNTFRYASARDSMTTSPDTIHDFKSGRDKIDLSQLMPSTDRVIFVDRLSFNGQTEMGQQY
NEVADITYLMIDFDAQVSECDMMIKFTGRHHFTANDFILSTSLTA

Specific function: Unknown

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR001818
- InterPro:   IPR016294
- InterPro:   IPR013858
- InterPro:   IPR006026
- InterPro:   IPR011049 [H]

Pfam domain/function: PF00353 HemolysinCabind; PF00413 Peptidase_M10; PF08548 Peptidase_M10_C [H]

EC number: NA

Molecular weight: Translated: 49619; Mature: 49619

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFMSYSREYSNTIIKNEQVMRRGIHYKNEVKGVIAPQISSRQSWKENTIHNKNTNLTYS
CEEECCCHHHHHHHHCCHHHHHHCCCCCHHCCEEECCCCCCCCCHHHCCCCCCCCCEEEE
FSRAYTLWDYDRTFQQNAYISLFNPAQIHQAKIAMQSWADVANISFTEASADSSANILFL
ECCEEEEECCCCHHCCCCEEEEECHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCEEEE
NFQRPSNVAGYAYYPNPGSFSPIWINYSFSDNQHPSRLNDGGGVLTHEIGHALGLGHSHA
EECCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCC
PHGYTQQMSVMSYLSEQGSGANYGQHYLSTPQMYDIAAIQYLYGANLHTRTGDTVYGFNS
CCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCEECCCCCEEEECCC
TSYRDHFTATHASDALIFCVWDAGGNDTFDFSGYKQNQMINLNELCFSDVGGLKGNVSIA
CCCCCCEEEECCCCEEEEEEEECCCCCCEECCCCCCCCEEEHHHHHHHHCCCCCCCEEEE
ADVTIENAIGGSGHDDIIGNHTNNILTGNGGSDQLWGNGGNNTFRYASARDSMTTSPDTI
EEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHH
HDFKSGRDKIDLSQLMPSTDRVIFVDRLSFNGQTEMGQQYNEVADITYLMIDFDAQVSEC
HHHHCCCCCEEHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHCEEEEEEEECCCCCCCC
DMMIKFTGRHHFTANDFILSTSLTA
EEEEEECCCEEEECCCEEEEEECCC
>Mature Secondary Structure
MMFMSYSREYSNTIIKNEQVMRRGIHYKNEVKGVIAPQISSRQSWKENTIHNKNTNLTYS
CEEECCCHHHHHHHHCCHHHHHHCCCCCHHCCEEECCCCCCCCCHHHCCCCCCCCCEEEE
FSRAYTLWDYDRTFQQNAYISLFNPAQIHQAKIAMQSWADVANISFTEASADSSANILFL
ECCEEEEECCCCHHCCCCEEEEECHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCEEEE
NFQRPSNVAGYAYYPNPGSFSPIWINYSFSDNQHPSRLNDGGGVLTHEIGHALGLGHSHA
EECCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCC
PHGYTQQMSVMSYLSEQGSGANYGQHYLSTPQMYDIAAIQYLYGANLHTRTGDTVYGFNS
CCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCEECCCCCEEEECCC
TSYRDHFTATHASDALIFCVWDAGGNDTFDFSGYKQNQMINLNELCFSDVGGLKGNVSIA
CCCCCCEEEECCCCEEEEEEEECCCCCCEECCCCCCCCEEEHHHHHHHHCCCCCCCEEEE
ADVTIENAIGGSGHDDIIGNHTNNILTGNGGSDQLWGNGGNNTFRYASARDSMTTSPDTI
EEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHH
HDFKSGRDKIDLSQLMPSTDRVIFVDRLSFNGQTEMGQQYNEVADITYLMIDFDAQVSEC
HHHHCCCCCEEHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHCEEEEEEEECCCCCCCC
DMMIKFTGRHHFTANDFILSTSLTA
EEEEEECCCEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211513 [H]