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The map label for this gene is ilvH [H]

Identifier: 22127513

GI number: 22127513

Start: 4034298

End: 4034822

Strand: Reverse

Name: ilvH [H]

Synonym: y3639

Alternate gene names: 22127513

Gene position: 4034822-4034298 (Counterclockwise)

Preceding gene: 161484748

Following gene: 22127512

Centisome position: 87.7

GC content: 51.81

Gene sequence:

>525_bases
GTGGCTAAGCAAAACGGAGAGGACTTAATTATGCGCCGCCGGATTTTATCAGTACTGCTGGAAAATGAGTCAGGTGCACT
CTCACGGGTGGTGGGGCTGTTTTCTCAGCGTGGCTATAATATCGAAAGCCTGACGGTCGCGCCAACCGATGACCCAACGC
TTTCCCGCATGACCATCCAGACCGTGGGTGATGCCAAGGTTCTGGAGCAGATTGAAAAGCAGCTGCACAAGTTGGTGGAC
GTCTTACGTGTCAGTGAGTTGGTTTCTGGCTCACATGTTGAGCGCGAAATCATGTTGGTGAAGTTGCAAGCCAGTGGTTA
TGGCCGTGAAGAGGTGAAGCGTTGTGCAGAAATCTTCCGTGGGCAAATTGTGGATGTGACCGCAACGCTCTATACCGTTC
AGCTAGCGGGTACTAGCGAGAAGCTGGATGCGTTTTTGAATGCGGTGCGTGAAGTCGCTGAAATAGTGGAAGTTGCTCGC
TCTGGGATTGTCGGCGTATCGCGTGGTGACAAAATCATGCGTTAA

Upstream 100 bases:

>100_bases
AATTATCCGAAACCAATCGTTTGGTCTTTGTGGATGTGACTGTCGATGAAACAGAACATGTTTACCCGATGCAGATTCGT
GGTGGTGGCATGGACGAAAT

Downstream 100 bases:

>100_bases
TTAATGCTGATTTCGCTCTAATGATCGGGCTCAGCGCATAGCGTTGAGCTTTTTTGTGCCCAGAAAACCCCCAGCTAGGC
TGGGGGTTCAGTAAAGCTTT

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: ALS-III; Acetohydroxy-acid synthase III small subunit; AHAS-III [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MAKQNGEDLIMRRRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDAKVLEQIEKQLHKLVD
VLRVSELVSGSHVEREIMLVKLQASGYGREEVKRCAEIFRGQIVDVTATLYTVQLAGTSEKLDAFLNAVREVAEIVEVAR
SGIVGVSRGDKIMR

Sequences:

>Translated_174_residues
MAKQNGEDLIMRRRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDAKVLEQIEKQLHKLVD
VLRVSELVSGSHVEREIMLVKLQASGYGREEVKRCAEIFRGQIVDVTATLYTVQLAGTSEKLDAFLNAVREVAEIVEVAR
SGIVGVSRGDKIMR
>Mature_173_residues
AKQNGEDLIMRRRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDAKVLEQIEKQLHKLVDV
LRVSELVSGSHVEREIMLVKLQASGYGREEVKRCAEIFRGQIVDVTATLYTVQLAGTSEKLDAFLNAVREVAEIVEVARS
GIVGVSRGDKIMR

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=162, Percent_Identity=87.6543209876543, Blast_Score=287, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6319837, Length=206, Percent_Identity=27.6699029126214, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 19226; Mature: 19094

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQNGEDLIMRRRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRMTIQ
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHH
TVGDAKVLEQIEKQLHKLVDVLRVSELVSGSHVEREIMLVKLQASGYGREEVKRCAEIFR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHC
GQIVDVTATLYTVQLAGTSEKLDAFLNAVREVAEIVEVARSGIVGVSRGDKIMR
CCHHEEEEHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
>Mature Secondary Structure 
AKQNGEDLIMRRRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRMTIQ
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHH
TVGDAKVLEQIEKQLHKLVDVLRVSELVSGSHVEREIMLVKLQASGYGREEVKRCAEIFR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHC
GQIVDVTATLYTVQLAGTSEKLDAFLNAVREVAEIVEVARSGIVGVSRGDKIMR
CCHHEEEEHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6308579; 1630901; 9278503; 1851954; 2198273 [H]