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The map label for this gene is sstT [H]

Identifier: 22127469

GI number: 22127469

Start: 3990393

End: 3991712

Strand: Direct

Name: sstT [H]

Synonym: y3595

Alternate gene names: 22127469

Gene position: 3990393-3991712 (Clockwise)

Preceding gene: 22127467

Following gene: 22127470

Centisome position: 86.73

GC content: 48.18

Gene sequence:

>1320_bases
ATGAAGGGTATAAACGGGCAGAACATATTAAATTTCACTTGGGAAGAGGCATTGCTAGAAGCTATGGAAAAGACACAGTC
TGTATTTATACGATTTATCGTCAACGGTAGTTTAGTGAAACAAATACTGATCGGTTTAGTTGCCGGTATTGTTTTAGCAT
TAGTATCGACTCCTGCAGCGATAGCGGTAGGGTTACTCGGTTCGCTGTTCGTGGGCGCATTAAAAGCCGTCGCGCCAGTT
TTAGTCTTGATGTTGGTCATAGCATCCATCGCCAACCATAAGAAAGGCCAAAAAACCAGTATTCGCCCTATTCTGTTCCT
GTATGTATTAGGGACATTCTCTGCGGCACTGGTTGCGGTTGTCGTCAGTTTTATCTACCCATCAACCCTTATTTTGGTGG
CTGAGAGTGCTGATATCACCCCACCGAGTGGGATTGTTGAAGTGCTACACGGTTTGCTAAACAGCATAATCGCCAACCCT
ATCCATGCGCTGCTCAATGCTAACTACATTGGTATTCTGGCTTGGGCTGTGGGTTTAGGTATTGCCTTGCGTCATGCTGC
CGATACCACCAAAGCATTGATTAATGATATGTCAGATGCCGTCACTTTGGTGGTCCGTGTGGTTATCCGTTTTGCACCGT
TGGGTATTTTTGGTTTGGTCGCGTCCACTATCGCAGCTACCGGCTTCGGTGCCTTACAGCTTTATGCGCAACTGTTAGTG
GTATTGATCGGCTGTATGTTACTGGTGGCATTAGTGGTCAACCCACTGATTGTTTACTGGAAGATTCGCCGTAATCCTTA
TCCATTGGTATTTGCTTGCCTGCGTGAAAGTGGCGTTACTGCCTTCTTTACCCGGAGTTCAGCCGCAAACATTCCAGTGA
ATATGGAAATGTGTAAGAAAATGAACCTGAATGAAGACACCTATTCGATCTCTATTCCGTTAGGTGCCACCATCAATATG
GCTGGTGCAGCCATCACCATCACGGTGCTGACACTGGCGGCGGTTCATACCCTAGGCATTACCGTTGACCTGCCAACAGC
CCTGCTACTGAGTGTGGTTGCGGCGATCTGTGCCTGTGGTGCATCCGGTGTTGCCGGTGGCTCTCTGTTACTGATCCCAC
TGGCTTGCAGCATGTTCGGCATTCCAAACGATGTGGCAATGCAAGTGGTTGGTGTTGGCTTCATTATCGGCGTATTGCAG
GATTCAGCCGAAACTGCACTGAACTCTTCAACCGATGTGTTGTTTACTGCAGCGGTCTGTCAGGCTGAGGATGCCAAACT
GGCTAATCCTGACCCACTGGCAGCGGGTAAGTCAGTCTAA

Upstream 100 bases:

>100_bases
TTGGCGTTGCAGCCAGGTAATAAAAAGCGAGGCCTGCATTACTGGTTTATATCAGTGATTCAGGTATGGAGAGCAGCTAG
CACCGCTGCAACTTCAGGTA

Downstream 100 bases:

>100_bases
ATACTCGGTTTTACCTACGCAAAATGCCAGTCAGTTAAGTTTGACTGGCATTTTTTTGTGCCCAGAAAACCCCCAGCTAG
GCTGGGGGTTCAGTAAAGCT

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MKGINGQNILNFTWEEALLEAMEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPV
LVLMLVIASIANHKKGQKTSIRPILFLYVLGTFSAALVAVVVSFIYPSTLILVAESADITPPSGIVEVLHGLLNSIIANP
IHALLNANYIGILAWAVGLGIALRHAADTTKALINDMSDAVTLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYAQLLV
VLIGCMLLVALVVNPLIVYWKIRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINM
AGAAITITVLTLAAVHTLGITVDLPTALLLSVVAAICACGASGVAGGSLLLIPLACSMFGIPNDVAMQVVGVGFIIGVLQ
DSAETALNSSTDVLFTAAVCQAEDAKLANPDPLAAGKSV

Sequences:

>Translated_439_residues
MKGINGQNILNFTWEEALLEAMEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPV
LVLMLVIASIANHKKGQKTSIRPILFLYVLGTFSAALVAVVVSFIYPSTLILVAESADITPPSGIVEVLHGLLNSIIANP
IHALLNANYIGILAWAVGLGIALRHAADTTKALINDMSDAVTLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYAQLLV
VLIGCMLLVALVVNPLIVYWKIRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINM
AGAAITITVLTLAAVHTLGITVDLPTALLLSVVAAICACGASGVAGGSLLLIPLACSMFGIPNDVAMQVVGVGFIIGVLQ
DSAETALNSSTDVLFTAAVCQAEDAKLANPDPLAAGKSV
>Mature_439_residues
MKGINGQNILNFTWEEALLEAMEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPV
LVLMLVIASIANHKKGQKTSIRPILFLYVLGTFSAALVAVVVSFIYPSTLILVAESADITPPSGIVEVLHGLLNSIIANP
IHALLNANYIGILAWAVGLGIALRHAADTTKALINDMSDAVTLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYAQLLV
VLIGCMLLVALVVNPLIVYWKIRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINM
AGAAITITVLTLAAVHTLGITVDLPTALLLSVVAAICACGASGVAGGSLLLIPLACSMFGIPNDVAMQVVGVGFIIGVLQ
DSAETALNSSTDVLFTAAVCQAEDAKLANPDPLAAGKSV

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI223468564, Length=254, Percent_Identity=28.3464566929134, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI223468566, Length=254, Percent_Identity=28.3464566929134, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI5032093, Length=254, Percent_Identity=28.3464566929134, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI4827012, Length=243, Percent_Identity=24.2798353909465, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI169790839, Length=288, Percent_Identity=24.3055555555556, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI66773030, Length=272, Percent_Identity=24.6323529411765, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI21314632, Length=259, Percent_Identity=27.4131274131274, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI40254478, Length=273, Percent_Identity=26.007326007326, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789473, Length=407, Percent_Identity=77.1498771498772, Blast_Score=609, Evalue=1e-176,
Organism=Escherichia coli, GI1790514, Length=439, Percent_Identity=23.6902050113895, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789947, Length=391, Percent_Identity=24.2966751918159, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17537407, Length=473, Percent_Identity=23.4672304439746, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71983099, Length=276, Percent_Identity=25.7246376811594, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71996953, Length=269, Percent_Identity=26.3940520446097, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71983106, Length=276, Percent_Identity=25.7246376811594, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193206505, Length=292, Percent_Identity=27.7397260273973, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24583025, Length=279, Percent_Identity=27.5985663082437, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17137668, Length=279, Percent_Identity=27.5985663082437, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583023, Length=279, Percent_Identity=27.5985663082437, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 45576; Mature: 45576

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGINGQNILNFTWEEALLEAMEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAA
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCHHH
IAVGLLGSLFVGALKAVAPVLVLMLVIASIANHKKGQKTSIRPILFLYVLGTFSAALVAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VVSFIYPSTLILVAESADITPPSGIVEVLHGLLNSIIANPIHALLNANYIGILAWAVGLG
HHHHHCCHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IALRHAADTTKALINDMSDAVTLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYAQLLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VLIGCMLLVALVVNPLIVYWKIRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKK
HHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHC
MNLNEDTYSISIPLGATINMAGAAITITVLTLAAVHTLGITVDLPTALLLSVVAAICACG
CCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHCC
ASGVAGGSLLLIPLACSMFGIPNDVAMQVVGVGFIIGVLQDSAETALNSSTDVLFTAAVC
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
QAEDAKLANPDPLAAGKSV
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKGINGQNILNFTWEEALLEAMEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAA
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCHHH
IAVGLLGSLFVGALKAVAPVLVLMLVIASIANHKKGQKTSIRPILFLYVLGTFSAALVAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VVSFIYPSTLILVAESADITPPSGIVEVLHGLLNSIIANPIHALLNANYIGILAWAVGLG
HHHHHCCHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IALRHAADTTKALINDMSDAVTLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYAQLLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VLIGCMLLVALVVNPLIVYWKIRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKK
HHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHC
MNLNEDTYSISIPLGATINMAGAAITITVLTLAAVHTLGITVDLPTALLLSVVAAICACG
CCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHCC
ASGVAGGSLLLIPLACSMFGIPNDVAMQVVGVGFIIGVLQDSAETALNSSTDVLFTAAVC
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
QAEDAKLANPDPLAAGKSV
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA