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The map label for this gene is cdd [H]

Identifier: 21910405

GI number: 21910405

Start: 926669

End: 927058

Strand: Reverse

Name: cdd [H]

Synonym: SpyM3_0869

Alternate gene names: 21910405

Gene position: 927058-926669 (Counterclockwise)

Preceding gene: 21910406

Following gene: 21910404

Centisome position: 48.78

GC content: 35.9

Gene sequence:

>390_bases
ATGGGGACTACTGATTTAGTAAGTTGTGCTGTACAAGCTAGTGAGTATGCTTATGTCCCTTACTCTCATTTTCCAGTAGG
AGCAGCTTTAAAAACAAAAGATGGAACGATCTATACTGGCTGTAATATTGAAAATGTTAGTTTTGGTCTGACAAATTGTG
GAGAGCGAACAGCTATATTTAAAGCCATATCTGATGGTCATAAAGAATTGGTTGAAATTGCTATTTATGGAGAAACTATG
CAACCTGTATCTCCTTGTGGGGCTTGTCGTCAGGTAATGGCAGAATTTTTTGCTCCTTCTTCTTTAGTCACTTTAATTGC
TAAAAATGGTCAAACTGTTGAAATGACTGTTGGAGATTTACTCCCCTATTCTTTTACAGATTTAATATAA

Upstream 100 bases:

>100_bases
AAGTTAGATCACGTTAATTATCTATCAAGTCGGGTGCATATTTCGTTAAAGTATCTACAGGGGTTTCAATAGATGTAGCT
ATTATGAAAGGTGATGTTAA

Downstream 100 bases:

>100_bases
TCTGCTTTAATTTCTGTTATCTAGCCGTCTTGGCTTTATATTTACTTTCAGCAACTTATTTGCTAGAAATCTTTTTTAGG
AGGGTTCATATTCATGAACA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIENVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETM
QPVSPCGACRQVMAEFFAPSSLVTLIAKNGQTVEMTVGDLLPYSFTDLI

Sequences:

>Translated_129_residues
MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIENVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETM
QPVSPCGACRQVMAEFFAPSSLVTLIAKNGQTVEMTVGDLLPYSFTDLI
>Mature_128_residues
GTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIENVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETMQ
PVSPCGACRQVMAEFFAPSSLVTLIAKNGQTVEMTVGDLLPYSFTDLI

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=122, Percent_Identity=50.8196721311475, Blast_Score=119, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17540514, Length=122, Percent_Identity=45.0819672131148, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17551074, Length=121, Percent_Identity=45.4545454545455, Blast_Score=102, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6323274, Length=119, Percent_Identity=38.655462184874, Blast_Score=89, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24582741, Length=127, Percent_Identity=40.9448818897638, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19920920, Length=137, Percent_Identity=38.6861313868613, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24582744, Length=142, Percent_Identity=37.3239436619718, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 13800; Mature: 13669

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIENVSFGLTNCGERTAIF
CCCHHHHHHHHHCCCEEECCCCCCCCCCEEECCCCEEEECCCCCCCEECCCCCCCHHHHH
KAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFAPSSLVTLIAKNGQTVEMTVGDL
HHHHCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHEEEEECCCCEEEEECCCC
LPYSFTDLI
CCCHHHHCC
>Mature Secondary Structure 
GTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIENVSFGLTNCGERTAIF
CCHHHHHHHHHCCCEEECCCCCCCCCCEEECCCCEEEECCCCCCCEECCCCCCCHHHHH
KAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFAPSSLVTLIAKNGQTVEMTVGDL
HHHHCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHEEEEECCCCEEEEECCCC
LPYSFTDLI
CCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]