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The map label for this gene is infC [H]

Identifier: 30410815

GI number: 30410815

Start: 132879

End: 133418

Strand: Direct

Name: infC [H]

Synonym: BUsg118

Alternate gene names: 30410815

Gene position: 132879-133418 (Clockwise)

Preceding gene: 21672408

Following gene: 21672409

Centisome position: 20.72

GC content: 30.56

Gene sequence:

>540_bases
ATTAAAGGCGGAAAAAGAATTCAATTCACGCGGCCGAATCGTATTAATAATGAAATTCGTGCCATTAAAGTTCGTCTTAC
TGGTGTCGAAGGCGATCAAATTGGGATAGTTAATTTACGTGAAGCTTTAGAAAAAGCTGAGGAATTAGGATTAGATTTAG
TAGAAATTAGTCCAAATGCAGAACCTCCAGTTTGTCGTATTATGGATTATGGCAAATTTCTTTATGAAAAAAGTAAATCT
TCTAAAGAACAGAAAAAAAAACAAAAGGTAATTCAAGTAAAAGAAATTAAATTTCGTCCTAGTACAGATGAAGGAGATTA
TCAAGTTAAATTACGTAATTTAATTCGTTTTTTAGAAGATGGGGATAAAGTTAAAATTACCCTACGATTTAGAGGACGTG
AAATGGCACATCAAAAAATAGGTATTGATGTGTTGAATAGAGTGAAAAATGATTTAATTGAATTAGCAATTATTGAATCA
TTTCCATCTAAAATCGAAGGTCGTCAAATGATTATGGTATTAGCACCAAAGAAAAAATAA

Upstream 100 bases:

>100_bases
AAATGGTTACAATTTAGGAATTATAGATATTGATTGTTTTATTAAAAAGTTACAAAAAGAAATTTTTACTCGTAGCTTTT
ATCAAATGGAGGAATAAAGT

Downstream 100 bases:

>100_bases
TAATTTTTGACTAAACATGCCAAAAAGAAATATGTAGTTTATTTTTTTTTACAATTAAAATGAAATATTTTATGCCAAAA
ATTAAAACTTTAAGAAGTGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MKGGKRIQFTRPNRINNEIRAIKVRLTGVEGDQIGIVNLREALEKAEELGLDLVEISPNAEPPVCRIMDYGKFLYEKSKS
SKEQKKKQKVIQVKEIKFRPSTDEGDYQVKLRNLIRFLEDGDKVKITLRFRGREMAHQKIGIDVLNRVKNDLIELAIIES
FPSKIEGRQMIMVLAPKKK

Sequences:

>Translated_179_residues
MKGGKRIQFTRPNRINNEIRAIKVRLTGVEGDQIGIVNLREALEKAEELGLDLVEISPNAEPPVCRIMDYGKFLYEKSKS
SKEQKKKQKVIQVKEIKFRPSTDEGDYQVKLRNLIRFLEDGDKVKITLRFRGREMAHQKIGIDVLNRVKNDLIELAIIES
FPSKIEGRQMIMVLAPKKK
>Mature_179_residues
MKGGKRIQFTRPNRINNEIRAIKVRLTGVEGDQIGIVNLREALEKAEELGLDLVEISPNAEPPVCRIMDYGKFLYEKSKS
SKEQKKKQKVIQVKEIKFRPSTDEGDYQVKLRNLIRFLEDGDKVKITLRFRGREMAHQKIGIDVLNRVKNDLIELAIIES
FPSKIEGRQMIMVLAPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=179, Percent_Identity=86.5921787709497, Blast_Score=290, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20660; Mature: 20660

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGGKRIQFTRPNRINNEIRAIKVRLTGVEGDQIGIVNLREALEKAEELGLDLVEISPNA
CCCCCEEEEECCCCCCCCEEEEEEEEEECCCCCEEHHHHHHHHHHHHHCCCEEEEECCCC
EPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPSTDEGDYQVKLRNLIRFLED
CCCEEHHHHHHHHHHHHHCCHHHHHHHHHHEEHEEEEECCCCCCCCEEEHHHHHHHHHCC
GDKVKITLRFRGREMAHQKIGIDVLNRVKNDLIELAIIESFPSKIEGRQMIMVLAPKKK
CCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MKGGKRIQFTRPNRINNEIRAIKVRLTGVEGDQIGIVNLREALEKAEELGLDLVEISPNA
CCCCCEEEEECCCCCCCCEEEEEEEEEECCCCCEEHHHHHHHHHHHHHCCCEEEEECCCC
EPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPSTDEGDYQVKLRNLIRFLED
CCCEEHHHHHHHHHHHHHCCHHHHHHHHHHEEHEEEEECCCCCCCCEEEHHHHHHHHHCC
GDKVKITLRFRGREMAHQKIGIDVLNRVKNDLIELAIIESFPSKIEGRQMIMVLAPKKK
CCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA