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The map label for this gene is fabD

Identifier: 21672614

GI number: 21672614

Start: 385044

End: 385976

Strand: Direct

Name: fabD

Synonym: BUsg338

Alternate gene names: 21672614

Gene position: 385044-385976 (Clockwise)

Preceding gene: 21672613

Following gene: 21672615

Centisome position: 60.03

GC content: 22.62

Gene sequence:

>933_bases
ATGAACTCATTTGCTATGTTATTTCCAGGTCAAGGTTCTCAGTATAAAAACATGTTATCTTCTTTTTTTCAAAAGAAAAA
TAATCTTTTTAAAAAAATATTTGATGAAGCATCAGAATATGTTAATTATAATTTATTAAATTTAATAAAAAATGGAGCTA
AGAAAAAAAGAGATGATTATAAATATATACAATCAGCTATTTTAACTTCATCAATTGCAATTTATCAATTGTGGAAAGAA
AAAAATGGAAGACGTCCTGCATTGATGTCAGGACATAGTTTAGGAGAATATTCAGCATTAGTTTGTGCTAATGCAATAAA
ATTTTCTGATGCTTTAAAAATAGTTAAATTAAGAAGCAAATTAATGCAAAAAATTATTATAAATAAACCATCTTTAGTAC
AGGCAATTATTGGTTTAGATAAAGTCATTATTAAAAATATATGTTTACAATATTTACCAAAAATTGTTTCTATAGCAAGC
ATCAATTCTGATGATCAAATTATTATTTCAGGAGAGAAATTAGCAGTGCGTGAAGTTGGTTTAAAGTGTAAAAAAAAGGG
AGCGAAGTATGTAATAAAATTAAATATTAATACACCAATACATAGTCAATTAATGAAACCTGTTTCAGAACAAATTAAAT
ACTTATTAAAATCTATTAAAATAAAATCTCCACAAATACCTGTCATTAACAATGTAGATGTTATATGTGAAAAAAATGAA
AAAAAAATAAAAAAAGCATTAGTTAGACAATTTTACAGTACTGTAAGGTGGAAAGAAATAATCGATTTAATAAAATCAAA
AAAAATTTTTACAATGTTAGAAATAGGACCAAATAAAATTTTAAGTAATTTAATAAAAAAAAACGATAATATTACTGTAT
TAAATACAAATAATTTAAAAAACTTTTTAATAGCATTCAAAACAATCCATTAG

Upstream 100 bases:

>100_bases
TAATAAATAAAAAAAAGGTACTTTTTTTAAAAAAAGTACCATTTTAAAAAAAATCATATTTATTTTAAAATAATTTATAT
CCTCAAAAAAGATAAATTTA

Downstream 100 bases:

>100_bases
AAAAATAATGAAAATTGAAAAAAAAACCGCATTAGTCACAGGAGCAAACCAAGGTCTTGGAAAAGAAATTGCTATAAAAT
TATCACAAAAGGGAATACAA

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MNSFAMLFPGQGSQYKNMLSSFFQKKNNLFKKIFDEASEYVNYNLLNLIKNGAKKKRDDYKYIQSAILTSSIAIYQLWKE
KNGRRPALMSGHSLGEYSALVCANAIKFSDALKIVKLRSKLMQKIIINKPSLVQAIIGLDKVIIKNICLQYLPKIVSIAS
INSDDQIIISGEKLAVREVGLKCKKKGAKYVIKLNINTPIHSQLMKPVSEQIKYLLKSIKIKSPQIPVINNVDVICEKNE
KKIKKALVRQFYSTVRWKEIIDLIKSKKIFTMLEIGPNKILSNLIKKNDNITVLNTNNLKNFLIAFKTIH

Sequences:

>Translated_310_residues
MNSFAMLFPGQGSQYKNMLSSFFQKKNNLFKKIFDEASEYVNYNLLNLIKNGAKKKRDDYKYIQSAILTSSIAIYQLWKE
KNGRRPALMSGHSLGEYSALVCANAIKFSDALKIVKLRSKLMQKIIINKPSLVQAIIGLDKVIIKNICLQYLPKIVSIAS
INSDDQIIISGEKLAVREVGLKCKKKGAKYVIKLNINTPIHSQLMKPVSEQIKYLLKSIKIKSPQIPVINNVDVICEKNE
KKIKKALVRQFYSTVRWKEIIDLIKSKKIFTMLEIGPNKILSNLIKKNDNITVLNTNNLKNFLIAFKTIH
>Mature_310_residues
MNSFAMLFPGQGSQYKNMLSSFFQKKNNLFKKIFDEASEYVNYNLLNLIKNGAKKKRDDYKYIQSAILTSSIAIYQLWKE
KNGRRPALMSGHSLGEYSALVCANAIKFSDALKIVKLRSKLMQKIIINKPSLVQAIIGLDKVIIKNICLQYLPKIVSIAS
INSDDQIIISGEKLAVREVGLKCKKKGAKYVIKLNINTPIHSQLMKPVSEQIKYLLKSIKIKSPQIPVINNVDVICEKNE
KKIKKALVRQFYSTVRWKEIIDLIKSKKIFTMLEIGPNKILSNLIKKNDNITVLNTNNLKNFLIAFKTIH

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family

Homologues:

Organism=Homo sapiens, GI51243059, Length=300, Percent_Identity=26.6666666666667, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1787334, Length=309, Percent_Identity=38.1877022653722, Blast_Score=235, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI71984332, Length=272, Percent_Identity=27.9411764705882, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17550940, Length=297, Percent_Identity=25.5892255892256, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=26.2458471760797, Blast_Score=101, Evalue=8e-22,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): FABD_BUCAP (Q8K9J6)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660681.1
- ProteinModelPortal:   Q8K9J6
- SMR:   Q8K9J6
- EnsemblBacteria:   EBBUCT00000000246
- GeneID:   1005568
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg338
- GeneTree:   EBGT00050000008204
- HOGENOM:   HBG687898
- OMA:   AQIEFQV
- BioCyc:   BAPH198804:BUSG338-MONOMER
- GO:   GO:0005488
- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036
- Gene3D:   G3DSA:3.40.366.10
- TIGRFAMs:   TIGR00128

Pfam domain/function: PF00698 Acyl_transf_1; SSF52151 Acyl_Trfase/lysoPlipase; SSF55048 Malonyl_transacylase_ACP-bd

EC number: =2.3.1.39

Molecular weight: Translated: 35352; Mature: 35352

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: NA

Important sites: ACT_SITE 93-93 ACT_SITE 201-201

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSFAMLFPGQGSQYKNMLSSFFQKKNNLFKKIFDEASEYVNYNLLNLIKNGAKKKRDDY
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHH
KYIQSAILTSSIAIYQLWKEKNGRRPALMSGHSLGEYSALVCANAIKFSDALKIVKLRSK
HHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LMQKIIINKPSLVQAIIGLDKVIIKNICLQYLPKIVSIASINSDDQIIISGEKLAVREVG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHH
LKCKKKGAKYVIKLNINTPIHSQLMKPVSEQIKYLLKSIKIKSPQIPVINNVDVICEKNE
HHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCH
KKIKKALVRQFYSTVRWKEIIDLIKSKKIFTMLEIGPNKILSNLIKKNDNITVLNTNNLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCEEEEECCCHH
NFLIAFKTIH
HHHHHHHCCC
>Mature Secondary Structure
MNSFAMLFPGQGSQYKNMLSSFFQKKNNLFKKIFDEASEYVNYNLLNLIKNGAKKKRDDY
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHH
KYIQSAILTSSIAIYQLWKEKNGRRPALMSGHSLGEYSALVCANAIKFSDALKIVKLRSK
HHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LMQKIIINKPSLVQAIIGLDKVIIKNICLQYLPKIVSIASINSDDQIIISGEKLAVREVG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHH
LKCKKKGAKYVIKLNINTPIHSQLMKPVSEQIKYLLKSIKIKSPQIPVINNVDVICEKNE
HHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCH
KKIKKALVRQFYSTVRWKEIIDLIKSKKIFTMLEIGPNKILSNLIKKNDNITVLNTNNLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCEEEEECCCHH
NFLIAFKTIH
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438