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The map label for this gene is nuoN

Identifier: 21672449

GI number: 21672449

Start: 178667

End: 180127

Strand: Direct

Name: nuoN

Synonym: BUsg159

Alternate gene names: 21672449

Gene position: 178667-180127 (Clockwise)

Preceding gene: 21672448

Following gene: 21672450

Centisome position: 27.85

GC content: 23.89

Gene sequence:

>1461_bases
ATGATAATTAATCTACAAGAATTAATAGCACTTTTACCTTTTTTAATTTTACTACTAACTGTAGTAATAGTTATTTTATC
TATCTCTTATAATCGCAATCATTTTTTTATTGCTTTTTTAACTATAATCAGTTTAATAGTTAGCCTTTGTTCATTGTATT
TTTTAATTGCTATAGTTCCTATTGATATCACTAGTTTGTTTCATATTACCAAACGTTCTATTTTATATATAAGTATGATT
ATAATTTCTAGTATCGCCACTTGTGTTTTTGCTTATCCTTGGTTGTTAAAATATGCTTTTAATAAAGAAGAATTTTATTT
GTTAACGCTTATTTCGACATTAGGTGCTATTTTTTTAACTATTTCTAATCATATGGCGTCTTTATTTATTAGTGTTGAGT
TAATGTCTTTACCAATCTTTGGTTTGATTGCTTATTCTAATTCTCAAAAATATTCTTTAGAAGCATCTTTTAAATATCTT
GTTTTATCTGGTGTTTCTTCTTCTTTTTTATTGCTTGGTATTTCATGGATATATGCTATTTCTGGAAATCTTAGTCTTTT
GTGCTTAAATCAAATTTTTTCCGATTTATCAAATAGTGAAAAAATGATGGTTTTATTCGGTATAATTATGGTATTAATGT
CTTTTTTCTTTAAATTATCTATGGTTCCTTTTCATTTATGGACAGCTGATATTTATCAAGGAACTCCTGCATCTGTTTTG
TCTTTTTTTTCTGTTTCTGGAAAAATCGCAATTTTTAGTATTTTACTTTATTTTTTTTCATACTTTTCAGTTTTTGATAA
TAAAGTAATATTTTTAATATTGTCATTAATTAGTTTTTTTTCAATATTATTTGGTAATTTAATGGCTATATTTCAAACGA
ATATCAAAAGGTTTTTTGGTTATTCATCTATATCACAAATAGGTTATTTATTAATAATACTGCTTGTATCAAAAGATGAG
TATTTTTTTTCTGTGCAAACTGGTGGGATTTTTTTACTTAATTATTTGTGTACTAATATAGTATATTTTGGTGTTATTAA
TTTATTTTCTAATTCTTGTGACTATGATATAGATTCAATTCATTTATACAAAGGTTTATTTTGGGTACAACCTCTTTTAG
CTAGTATAGTTACAATTGTACTACTTTCTTTAGGAGGAATTCCTATAACTTTAGGATTTTTTGGGAAATTTTGTATTTTT
TCTATTATTATAAAAAATCATTTATGGACTATTGGTGCTTCATTCTTGATTGGTACAATATTAGGTTTATATGGCTATTT
AAGATTAATTGTTAATATGTATTTAAATCCATCGGAACAATCATTCATTAATGATATAAAAAAATCTAATTTTTGGTTAT
GTAGTCCTTCCGGGATTTTAATATTCATTTCTGGAATAATGTTATTGATATTAGGAATATATCCTAATCCATTAATTAAC
TTGATAAATTCAGTTCAATAA

Upstream 100 bases:

>100_bases
CAAAAAATATTAAATATTTCATTTGAATCGATACATTTTATATATAATTTTTCAAAAAGAATTCAGTAATTCTATTTTAA
AGATAAGGTTATGATTAATA

Downstream 100 bases:

>100_bases
TTTAATAAGTTAGTTTTTATATGAAATTGATCATTTTTATTAAAAAATATAATAAGAATATTTTTAATGATTTATTTTTT
TATCTCATCATTGTTTTTTT

Product: NADH dehydrogenase I chain N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MIINLQELIALLPFLILLLTVVIVILSISYNRNHFFIAFLTIISLIVSLCSLYFLIAIVPIDITSLFHITKRSILYISMI
IISSIATCVFAYPWLLKYAFNKEEFYLLTLISTLGAIFLTISNHMASLFISVELMSLPIFGLIAYSNSQKYSLEASFKYL
VLSGVSSSFLLLGISWIYAISGNLSLLCLNQIFSDLSNSEKMMVLFGIIMVLMSFFFKLSMVPFHLWTADIYQGTPASVL
SFFSVSGKIAIFSILLYFFSYFSVFDNKVIFLILSLISFFSILFGNLMAIFQTNIKRFFGYSSISQIGYLLIILLVSKDE
YFFSVQTGGIFLLNYLCTNIVYFGVINLFSNSCDYDIDSIHLYKGLFWVQPLLASIVTIVLLSLGGIPITLGFFGKFCIF
SIIIKNHLWTIGASFLIGTILGLYGYLRLIVNMYLNPSEQSFINDIKKSNFWLCSPSGILIFISGIMLLILGIYPNPLIN
LINSVQ

Sequences:

>Translated_486_residues
MIINLQELIALLPFLILLLTVVIVILSISYNRNHFFIAFLTIISLIVSLCSLYFLIAIVPIDITSLFHITKRSILYISMI
IISSIATCVFAYPWLLKYAFNKEEFYLLTLISTLGAIFLTISNHMASLFISVELMSLPIFGLIAYSNSQKYSLEASFKYL
VLSGVSSSFLLLGISWIYAISGNLSLLCLNQIFSDLSNSEKMMVLFGIIMVLMSFFFKLSMVPFHLWTADIYQGTPASVL
SFFSVSGKIAIFSILLYFFSYFSVFDNKVIFLILSLISFFSILFGNLMAIFQTNIKRFFGYSSISQIGYLLIILLVSKDE
YFFSVQTGGIFLLNYLCTNIVYFGVINLFSNSCDYDIDSIHLYKGLFWVQPLLASIVTIVLLSLGGIPITLGFFGKFCIF
SIIIKNHLWTIGASFLIGTILGLYGYLRLIVNMYLNPSEQSFINDIKKSNFWLCSPSGILIFISGIMLLILGIYPNPLIN
LINSVQ
>Mature_486_residues
MIINLQELIALLPFLILLLTVVIVILSISYNRNHFFIAFLTIISLIVSLCSLYFLIAIVPIDITSLFHITKRSILYISMI
IISSIATCVFAYPWLLKYAFNKEEFYLLTLISTLGAIFLTISNHMASLFISVELMSLPIFGLIAYSNSQKYSLEASFKYL
VLSGVSSSFLLLGISWIYAISGNLSLLCLNQIFSDLSNSEKMMVLFGIIMVLMSFFFKLSMVPFHLWTADIYQGTPASVL
SFFSVSGKIAIFSILLYFFSYFSVFDNKVIFLILSLISFFSILFGNLMAIFQTNIKRFFGYSSISQIGYLLIILLVSKDE
YFFSVQTGGIFLLNYLCTNIVYFGVINLFSNSCDYDIDSIHLYKGLFWVQPLLASIVTIVLLSLGGIPITLGFFGKFCIF
SIIIKNHLWTIGASFLIGTILGLYGYLRLIVNMYLNPSEQSFINDIKKSNFWLCSPSGILIFISGIMLLILGIYPNPLIN
LINSVQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Homo sapiens, GI251831108, Length=316, Percent_Identity=24.3670886075949, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI145693160, Length=485, Percent_Identity=46.5979381443299, Blast_Score=440, Evalue=1e-125,
Organism=Escherichia coli, GI1788829, Length=266, Percent_Identity=22.1804511278195, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1788831, Length=353, Percent_Identity=23.5127478753541, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON_BUCAP (Q8K9X5)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660516.1
- EnsemblBacteria:   EBBUCT00000000362
- GeneID:   1005357
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg159
- GeneTree:   EBGT00050000007699
- HOGENOM:   HBG747830
- OMA:   ILSISYN
- ProtClustDB:   CLSK315621
- BioCyc:   BAPH198804:BUSG159-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 54819; Mature: 54819

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xbf80a6c)-; HASH(0xb277558)-; HASH(0xbfac994)-; HASH(0xbbfff24)-; HASH(0xbfac9b8)-; HASH(0xb3b6338)-; HASH(0xb3492fc)-; HASH(0xb2f57e0)-; HASH(0xc4c1ff8)-; HASH(0xc17698c)-; HASH(0xbbe98fc)-; HASH(0xb359084)-; HASH(0xb2f557c)-; HASH(0xbbf97c4)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIINLQELIALLPFLILLLTVVIVILSISYNRNHFFIAFLTIISLIVSLCSLYFLIAIVP
CEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IDITSLFHITKRSILYISMIIISSIATCVFAYPWLLKYAFNKEEFYLLTLISTLGAIFLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ISNHMASLFISVELMSLPIFGLIAYSNSQKYSLEASFKYLVLSGVSSSFLLLGISWIYAI
HHHHHHHHHHHHHHHHCCHHHEEEECCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHH
SGNLSLLCLNQIFSDLSNSEKMMVLFGIIMVLMSFFFKLSMVPFHLWTADIYQGTPASVL
CCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHH
SFFSVSGKIAIFSILLYFFSYFSVFDNKVIFLILSLISFFSILFGNLMAIFQTNIKRFFG
HHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YSSISQIGYLLIILLVSKDEYFFSVQTGGIFLLNYLCTNIVYFGVINLFSNSCDYDIDSI
CHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
HLYKGLFWVQPLLASIVTIVLLSLGGIPITLGFFGKFCIFSIIIKNHLWTIGASFLIGTI
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLYGYLRLIVNMYLNPSEQSFINDIKKSNFWLCSPSGILIFISGIMLLILGIYPNPLIN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCCCHHHH
LINSVQ
HHHCCH
>Mature Secondary Structure
MIINLQELIALLPFLILLLTVVIVILSISYNRNHFFIAFLTIISLIVSLCSLYFLIAIVP
CEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IDITSLFHITKRSILYISMIIISSIATCVFAYPWLLKYAFNKEEFYLLTLISTLGAIFLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ISNHMASLFISVELMSLPIFGLIAYSNSQKYSLEASFKYLVLSGVSSSFLLLGISWIYAI
HHHHHHHHHHHHHHHHCCHHHEEEECCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHH
SGNLSLLCLNQIFSDLSNSEKMMVLFGIIMVLMSFFFKLSMVPFHLWTADIYQGTPASVL
CCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHH
SFFSVSGKIAIFSILLYFFSYFSVFDNKVIFLILSLISFFSILFGNLMAIFQTNIKRFFG
HHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YSSISQIGYLLIILLVSKDEYFFSVQTGGIFLLNYLCTNIVYFGVINLFSNSCDYDIDSI
CHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
HLYKGLFWVQPLLASIVTIVLLSLGGIPITLGFFGKFCIFSIIIKNHLWTIGASFLIGTI
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLYGYLRLIVNMYLNPSEQSFINDIKKSNFWLCSPSGILIFISGIMLLILGIYPNPLIN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCCCHHHH
LINSVQ
HHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12089438