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The map label for this gene is argC

Identifier: 21672338

GI number: 21672338

Start: 52469

End: 53473

Strand: Direct

Name: argC

Synonym: BUsg045

Alternate gene names: 21672338

Gene position: 52469-53473 (Clockwise)

Preceding gene: 21672336

Following gene: 21672339

Centisome position: 8.18

GC content: 27.06

Gene sequence:

>1005_bases
ATGTTGAATGTGTTAATTGTTGGTGCTAGTGGATATTCTGGTGCGGAATTAGTTAATTATATTAACCGTCATATGTTTTC
TAAAATTAAAAAAATTTTTGTTTCAGAAAATAGTTCTCATATAGGTAAATTATTTTCAGAATTACATCAAGAATTTAAAA
ATATTATAGATTTACCATTTGAAGCAATCAACTATGATACTTTAATTGAAAAAGATATTGATGCTGTTTTTTTAGCTACT
GATCATCACGTTAGTTACTCTCTTGTGCCCTTTTTTTTATCTCTTAATTGTGTTGTTTTTGATTTATCTGGTGCTTATAG
AGTTAAAAACACTGATACTTATTTAAAGTATTATGGTTTTTCTCATCAACATCAAGATATCTTAAAACGATCTGTATATG
GATTGGCTGAATGGAATAAGCAAGAAATTAAAAAAGCTGAATTAATTGCTGTTCCAGGATGTTACGCAACGTGTATACAA
TTGGCATTAAAACCTCTTATAAAAGAAAATTTTTTAAATGATGAATTTATTCCAATTATTAATGCTATAAGTGGTGTTAG
CGGAGCTGGTAGAAAAGCTAATATTACTAATAGTTTTTGTGAAGTTAGTTTGCATCCATATAATGTTTTTACTCATCGTC
ATACTCCTGAAATTATAGAGCATTTAGGTATCCCAGTGATTTTTATTCCTCATTTAGGTTCCTTTTCACGTGGAATTCTT
GCTAGTATTACATGTAAGTTAAAATGTAATTTTACATTCCAGGATATTTATAATTTATATAATACAGTTTATAAAGAAAA
ACCATTAATTCGAGTATATGAAAAAAATTTTCCTAGTATTAAAGCTGTGGTAAAATTACCTTTTTGTGATATTGGATTTA
TCATCCAAGATAAATATATCGTTATTATAGCTGCTGAAGATAATTTATTGAAAGGTGCAGCTGCACAAGCTATACAATGT
TTTAATATTCGTTTTGGATTTTCTGAAATTGAATCAATTATTTAA

Upstream 100 bases:

>100_bases
AAAATAAAAAATATCAATAAAATTTAATAATTAATAGAATTTATTTTAATTAACTGATTCTTTTTTTTAATATTTTTATT
TTTTTAAGGTTTATTAATTT

Downstream 100 bases:

>100_bases
ATGAGGTATTTTTTGATGATGAGTCCTTTGGTTATTAAATTAGGTGGAGTTCTTTTAGAAAGTGATAATGCAATGATGCG
TTTGTTTAAAGCGCTTCTTG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MLNVLIVGASGYSGAELVNYINRHMFSKIKKIFVSENSSHIGKLFSELHQEFKNIIDLPFEAINYDTLIEKDIDAVFLAT
DHHVSYSLVPFFLSLNCVVFDLSGAYRVKNTDTYLKYYGFSHQHQDILKRSVYGLAEWNKQEIKKAELIAVPGCYATCIQ
LALKPLIKENFLNDEFIPIINAISGVSGAGRKANITNSFCEVSLHPYNVFTHRHTPEIIEHLGIPVIFIPHLGSFSRGIL
ASITCKLKCNFTFQDIYNLYNTVYKEKPLIRVYEKNFPSIKAVVKLPFCDIGFIIQDKYIVIIAAEDNLLKGAAAQAIQC
FNIRFGFSEIESII

Sequences:

>Translated_334_residues
MLNVLIVGASGYSGAELVNYINRHMFSKIKKIFVSENSSHIGKLFSELHQEFKNIIDLPFEAINYDTLIEKDIDAVFLAT
DHHVSYSLVPFFLSLNCVVFDLSGAYRVKNTDTYLKYYGFSHQHQDILKRSVYGLAEWNKQEIKKAELIAVPGCYATCIQ
LALKPLIKENFLNDEFIPIINAISGVSGAGRKANITNSFCEVSLHPYNVFTHRHTPEIIEHLGIPVIFIPHLGSFSRGIL
ASITCKLKCNFTFQDIYNLYNTVYKEKPLIRVYEKNFPSIKAVVKLPFCDIGFIIQDKYIVIIAAEDNLLKGAAAQAIQC
FNIRFGFSEIESII
>Mature_334_residues
MLNVLIVGASGYSGAELVNYINRHMFSKIKKIFVSENSSHIGKLFSELHQEFKNIIDLPFEAINYDTLIEKDIDAVFLAT
DHHVSYSLVPFFLSLNCVVFDLSGAYRVKNTDTYLKYYGFSHQHQDILKRSVYGLAEWNKQEIKKAELIAVPGCYATCIQ
LALKPLIKENFLNDEFIPIINAISGVSGAGRKANITNSFCEVSLHPYNVFTHRHTPEIIEHLGIPVIFIPHLGSFSRGIL
ASITCKLKCNFTFQDIYNLYNTVYKEKPLIRVYEKNFPSIKAVVKLPFCDIGFIIQDKYIVIIAAEDNLLKGAAAQAIQC
FNIRFGFSEIESII

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=334, Percent_Identity=57.7844311377245, Blast_Score=410, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6320913, Length=350, Percent_Identity=29.4285714285714, Blast_Score=110, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_BUCAP (Q8KA61)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660405.1
- ProteinModelPortal:   Q8KA61
- SMR:   Q8KA61
- EnsemblBacteria:   EBBUCT00000000220
- GeneID:   1005861
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg045
- GeneTree:   EBGT00050000007856
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- BioCyc:   BAPH198804:BUSG045-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37835; Mature: 37835

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 154-154

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNVLIVGASGYSGAELVNYINRHMFSKIKKIFVSENSSHIGKLFSELHQEFKNIIDLPF
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCH
EAINYDTLIEKDIDAVFLATDHHVSYSLVPFFLSLNCVVFDLSGAYRVKNTDTYLKYYGF
HHCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCEEEEEECCCCEEECCCCCEEEECCC
SHQHQDILKRSVYGLAEWNKQEIKKAELIAVPGCYATCIQLALKPLIKENFLNDEFIPII
CCHHHHHHHHHHHHHHCCCHHHCCHHHEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
NAISGVSGAGRKANITNSFCEVSLHPYNVFTHRHTPEIIEHLGIPVIFIPHLGSFSRGIL
HHHCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCHHHHHHCCCCEEEECCCCCCCCCCE
ASITCKLKCNFTFQDIYNLYNTVYKEKPLIRVYEKNFPSIKAVVKLPFCDIGFIIQDKYI
EEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCCEEEECCEE
VIIAAEDNLLKGAAAQAIQCFNIRFGFSEIESII
EEEECCCCHHHHHHHHHEEEEEEEECHHHHHHCC
>Mature Secondary Structure
MLNVLIVGASGYSGAELVNYINRHMFSKIKKIFVSENSSHIGKLFSELHQEFKNIIDLPF
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCH
EAINYDTLIEKDIDAVFLATDHHVSYSLVPFFLSLNCVVFDLSGAYRVKNTDTYLKYYGF
HHCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCEEEEEECCCCEEECCCCCEEEECCC
SHQHQDILKRSVYGLAEWNKQEIKKAELIAVPGCYATCIQLALKPLIKENFLNDEFIPII
CCHHHHHHHHHHHHHHCCCHHHCCHHHEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
NAISGVSGAGRKANITNSFCEVSLHPYNVFTHRHTPEIIEHLGIPVIFIPHLGSFSRGIL
HHHCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCHHHHHHCCCCEEEECCCCCCCCCCE
ASITCKLKCNFTFQDIYNLYNTVYKEKPLIRVYEKNFPSIKAVVKLPFCDIGFIIQDKYI
EEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCCEEEECCEE
VIIAAEDNLLKGAAAQAIQCFNIRFGFSEIESII
EEEECCCCHHHHHHHHHEEEEEEEECHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438